scholarly journals Risk Factors Analysis for Abnormal Semen Characteristics in Sub-Fertile Male

2019 ◽  
Vol 31 (1) ◽  
pp. 31-35
Author(s):  
Afroza Akhter ◽  
Liza Chowdury ◽  
Mahbuba Akhter ◽  
Samira Haque
Keyword(s):  
Risk Factors ◽  
Sperm Count ◽  
Semen Analysis ◽  
Male Partner ◽  
Semen Parameters ◽  
Military Hospital ◽  
Surgical Trauma ◽  
Heavy Smoking ◽  
Sperm Abnormality ◽  
The Mean

Introduction: This study aimed to identify the risk factors for abnormal semen parameters in male partner of sub-fertile couples. Materials & Methods: This was a prospective study of 100 diagnosed infertile & sub-fertile couples in the age group between 23-58 yrs old male were from 1st March 2013 to 28th Feb 2014 treated in Dhaka Combined Military Hospital (CMH). On the basis of sperm count the cases were grouped as follows. normozoospermia, oligozoospermia & azoospermia. Semen analysis was done in all the cases, The results were described with arithmetic mean and standard deviation. Male partners with normal semen parameters was undertaken among the sub-fertile couples attending the General Outpatient Department (GOPD) of CMH Dhaka. The history was taken from selected individual and it includes personal, socio-economics, occupational, medical, surgical history and drug intake to find out risk factors for abnormal semen parameters. Results: In Normozoospermia mean and SD of sperm count, sperm abnormally, sperm motillity were 65.98±5.05, 24.44±1.57 and 45.5±2.94 respectively. In 0ligozoospermia the mean and SD of sperm count, sperm abnormality, sperm mtility were 7.74±1.23, 41.1±3.78, 14.54±2.77 respectively. In azoospermia the mean and SD of sperm count, sperm abnormality, sperm motility were absent. Conclusion: Here data statistically showed person with normozoospermia having good sperm morphology & motility than oligozoospermia and azoospermic subjects thereby causing male infertility which was responsible for hindrance in achieving pregnancy clinically. Using tight undergarment or working in hot atmosphere depresses spermatogenesis. Mumps orchitis permanently damage spermatogenesis. Bacterial or viral infection depresses the sperm count. Diabetes, malnutrition, heavy smoking reduces spermatogenesis. β-blocker, antihypertensive were likely to hinder spermatogenesis. The efferent ducts might be obstructed by infection like tubercular, gonococcal or by surgical trauma. Medicine Today 2019 Vol.31(1): 31-35

scholarly journals ASSOCIATION OF VARICOCELE WITH OLIGOSPERMIA AND AZOSPERMIA

1969 ◽  
Vol 3 (2) ◽  
pp. 303-307
Author(s):  
NAIK ZADA ◽  
SHAFI ULLAH KHAN ◽  
RIAZ AHMAD KHAN
Keyword(s):  
Sperm Count ◽  
Human Subjects ◽  
Semen Analysis ◽  
Cross Sectional Study ◽  
Semen Parameters ◽  
Male Factor ◽  
Cross Sectional ◽  
Seminal Parameters ◽  
The Mean ◽  
Age Range

OBJECTIVE: To determine the frequency of abnormal semen parameters among patients presenting withvaricocele1METHODS:It was a descriptive cross-sectional study conducted at the Department of Urology Institute ofkidney diseases Hayat Abad Medical Complex Peshawar and Cenna hospital Saidu Sharif Swat. The studywas carried out on 139 human subjects with clinical evidence of varicocele between age range of 15-45years.The diagnosis of varicocele was based on palpable and/or visible scrotal lump of testicular veins(pampiniform plexus) and was diagnosed on the basis of clinical examination. Semen analysis was carriedout in all these patients and information wascollected on pre designed proforma.RESULTS:The study included a total of 139 patients with varicocele. The mean age of patient was 30 years(15-45) among the patients having symptoms of varicocele. The Mean ±SD for duration of varicocelesymptoms was 9.32 ± 9.70 months. 6.5% (n=9) patients were having azoospermia and 20.1% (n=28)patients had oligozoospermia.CONCLUSION: Patients with varicocele have poor seminal parameters in terms of sperm count i.e.oligozoospermia and azoospermia responsible for male factor infertility in majority ofcases.KEYWORDS:varicocele;seminal parameters;sperm count, infertility

scholarly journals SEMEN ANALYSIS; CORNER STONE IN EVALUATING INFERTILITY

2022 ◽  
Vol 71 (6) ◽  
pp. 2224-27
Author(s):  
Aysha Khan ◽  
Zunera Shahbaz ◽  
Shagufta Yousaf ◽  
Abeera Ahmed ◽  
Fatima Sana ◽  
...  
Keyword(s):  
Sperm Count ◽  
Semen Analysis ◽  
Cross Sectional Study ◽  
World Health ◽  
Semen Parameters ◽  
Military Hospital ◽  
Normal Male ◽  
Cross Sectional ◽  
Normal Sperm ◽  
Health Organization

Objective: To study the patterns and distribution of various abnormal semen parameters in infertile males. Study Design: Cross sectional study. Place and Duration of Study: Department of Pathology, Combined Military Hospital, Karachi, from Nov 2019 to Oct 2020. Methodology: The study included 364 patients who presented with primary and secondary infertility. Consecutive convenient sampling was done. Semen analysis was performed using World Health Organization latest guidelines. Samples were categorized as normospermia, azoospermia, oligospermia, asthenozoospermia and necrospermia. Results: The study comprised of 364 samples of infertile males. Normal sperm count was observed in 317 (87%) males, azoospermia in 28 (7.6%) and oligospermia in 19 (5.2%) males. Low ejaculated volume and higher non-motile sperms were noted in oligospermia samples in comparison with normospermia samples. Asthenozoospermia was observed in 102 (28%) and oligoasthenospermia was noted in 15 (4.1%) samples. Conclusion: Good quality semen analysis is a corner stone to diagnose the cause of male infertility.Sperm concentration and motility are the important markers of normal male reproductive system and are related to each other.

scholarly journals Effect of SARS-CoV-2 infection on semen parameters

2021 ◽  
Vol 16 (3) ◽  
Author(s):  
Mustafa Bilal Hamarat ◽  
Mehmet Serkan Ozkent ◽  
Burak Yılmaz ◽  
Salih Yahya Aksanyar ◽  
Kadir Karabacak
Keyword(s):  
Sperm Count ◽  
Semen Analysis ◽  
Sperm Concentration ◽  
Semen Parameters ◽  
Positive Polymerase Chain Reaction ◽  
Normal Morphology ◽  
Before And After ◽  
Time Of Infection ◽  
The Mean ◽  
Pcr Test

Introduction: There are not enough studies showing the degree to which the SARS-CoV-2 virus affects the semen parameters after coronavirus infection in comparison to before they were infected. In this study, we aimed to assess the effect of SARS-CoV-2 infection on semen parameters. Methods: Patients were screened if they had had semen analysis performed from October 1, 2019, to December 1, 2020, in the assisted reproduction unit and later had positive polymerase chain reaction (PCR) test for SARS-CoV-2 infection. The patients’ semen parameters were recorded before and after SARS-CoV-2 infection, along with degrees of SARS-CoV-2 infection, dates of SARS-CoV-2 infection, durations between the treatment for SARS-CoV-2 infection and the second semen analysis, time of symptom onset, duration of their symptoms, ages, comorbidities, and any medications patients were taking. Results: Forty-one patients were included in the study. The mean age of the patients was 31.29±5.95 years. The mean duration from first semen analysis to the PCR test was 7.74±3.03 months. The mean duration between the PCR test and later semen analysis was 2.35±1.35 months. The median sperm concentration for the patients before and after SARS-CoV-2 infection were 24 mil/ml and 13 mil/ml, respectively (p<0.001). The normal morphology percentage before infection was 3.16±0.92, while it was 2.44±1.04 after infection (p=0.011). In 26 patients, the period from the time of infection to the second semen analysis was over 70 days, while this period was less than 70 days in the other 15 patients; however, in both patient groups, a significant decrease was detected in the sperm concentrations and total sperm count. Conclusions: In the semen samples we assessed, we observed a significant decrease in the mean sperm concentration, total sperm count, and mean percentage of samples with normal morphology after SARS-CoV-2 infection.

scholarly journals Semen analysis and sperm function parameters in patients with infertility in Navi Mumbai and Panvel region

2019 ◽  
Vol 8 (11) ◽  
pp. 4169
Author(s):  
Surekha Bhalekar ◽  
Shweta Ganorkar ◽  
Hemant Bhalekar ◽  
Prakash Roplekar
Keyword(s):  
Sperm Count ◽  
Semen Analysis ◽  
Male Partner ◽  
Age Groups ◽  
Clinical Problem ◽  
Semen Parameters ◽  
Sperm Function ◽  
Male Factor Infertility ◽  
Male Factor ◽  
Cross Sectional

Background: Although semen analysis is routinely used to evaluate male partner in infertile couples, infertility and problems of impaired fecundity have been a concern through ages and is also a significant clinical problem today, which affects 8-12% of couples worldwide. Aim of the study was to study different semen parameters in male factor infertility (MFI) and thus increasing the awareness regarding same.Methods: This is cross sectional study conducted between period of September 2016 to December 2018. Semen of 150 patients were studied and results were analysed as per recent WHO (2010) criteria.Results: The present study included 150 patients whose age ranged from 24 to 51 years. Patients were divided into different age groups and sperm count was studied in each group. Abnormal sperm morphology was studied with respect to sperm head, neck, tail defects and combined defects. Sperm deformity index (SDI) and Teratozoospermic index (TZI) were calculated. Other parameters including semen volume, pH, liquefaction time, sperm vitality and motility were also studied which showed significant variations. Conclusions: Although semen analysis is first and most informative investigation for evaluation of male factor infertility, studying individual semen parameters and sperm function and increasing its awareness in general population especially in developing countries is equally important. Besides, it is necessary to acknowledge its limitation with respect to collection, processing, evaluation and biological variation of samples. Also, a normal semen analysis may not prove successful fertility potential of an individual.

scholarly journals Impact of percutaneous embolization versus subinguinal microsurgical ligation on semen parameters in primary varicocele patients: comparative study

2020 ◽  
Vol 51 (1) ◽  
Author(s):  
Haytham M. Nasser ◽  
Ahmed Hussein ◽  
Gad M. Behairy ◽  
Mostafa Abdo
Keyword(s):  
Sperm Count ◽  
Semen Analysis ◽  
Statistical Significance ◽  
Semen Parameters ◽  
Male Factor ◽  
Percutaneous Embolization ◽  
Significant Difference ◽  
Group 2 ◽  
Group 1

Abstract Background Varicocele is an abnormally dilated pampiniform plexus of the veins within the spermatic cord and is considered the most common correctable cause of male factor infertility. Many approaches are described for treatment either surgical (tradition inguinal, subinguinal, and laparoscopic) or non-surgical percutaneous embolization. During the period from August 2017 to December 2018, we prospectively analyzed the preoperative and post-operative alteration of semen parameters (at 3 and 9 months) of the data collected from 63 patients with clinically evident varicocele referred to our tertiary hospital. Patients were divided into two groups: group 1, thirty-three patients who underwent subinguinal microsurgical ligation, and group 2, thirty patients who underwent percutaneous embolization. Results Sixty-three patients enrolled in this study were divided in two groups: group 1, patients who underwent surgery, and group 2, patients who underwent embolization; the mean age is 24.6 ± 1.27 years in group 1 and 23.7 ± 2 years in group 2; there was no statistically significant difference between the two groups as regards BMI, diabetes, hypertension, and smoking. Bilaterality was present in 15.2% of group 1 patients and 10% in group 2 patients (P value 0.06). Most of the patients were classified as grades 2 and 3 with no statistical significance regarding severity of the disease. Preoperative semen parameters for patients including sperm count, motility, and abnormal forms showed no statistically significant difference between the two groups. Post-intervention semen analysis was done twice during follow-up after 3 months and 9 months from the date of intervention. After 3 months, the semen parameters were improved in both groups in spite of the higher sperm count in group 2 but with no statistical significance. After 9 months follow-up, semen analysis showed persistent increase in sperm mobility in group 1 patients in comparison to group 2 patients. Both groups had better improvement in count of normal form with no statistical significant change. Conclusion Improvement of semen parameters while treating primary varicocele by either subinguinal microsurgery approach or percutaneous embolization shows equivalent outcomes.

scholarly journals SEMEN pH;

2012 ◽  
Vol 19 (02) ◽  
pp. 234-241
Author(s):  
HENRY. A. MWAKYOMA ◽  
ERICK. P. MAGOROSA
Keyword(s):  
Hormonal Regulation ◽  
Seminal Fluid ◽  
Sperm Count ◽  
Semen Analysis ◽  
Staining Technique ◽  
Semen Parameters ◽  
Morphological Examination ◽  
Pathology Laboratory ◽  
Cross Sectional ◽  
The World

Background: Male infertility is a frequent reproductive health problem in the world. It is usually related to abnormal spermproduction or function and these abnormalities can occur anywhere in the production of sperm including hormonal regulation, storage andtransport of sperm. Various factors are known to be responsible for seminal fluid abnormalities. Usually the first step in evaluating for maleinfertility is semen analysis. Setting: The study was conducted at Muhimbili National Hospital mainly in the department of Pathology laboratory,cytology unit. Study design: The study was a hospital based cross-sectional type. Objective: To determine semen pH in patients presenting withinfertility complains and relate how pH of seminal fluid and other semen parameters influence each other. Material and methods: Beforesemen collection, patients were instructed to abstain from sexual intercourse for a minimum of 48 hours to 7 days and collect semen bymasturbation and transport it to the laboratory through shirt pocket. Semen was to reach the laboratory for examination in not more than onehour from time of collection. Semen was examined macroscopically for volume, colour, viscosity and pH by using a pH meter (Consort C830)followed by microscopic examination which included motility of spermatozoa and sperm count by using Neuber counting chamber. The smearwas made on glass slides, fixed in 95% ethyl alcohol for 30 minutes then stained by using Papanicolaou’s staining technique and then analyzedmicroscopically for morphological examination. Results: In the analysis of the influence of semen parameters on semen pH, there wasdecrease in seminal fluid pH with age whereby as age increased the pH of seminal fluid decreased.. The general trend observed was that thepH of seminal fluid tended to decrease with an increase in the days of abstinence. pH tended to decrease with an increase of seminal fluidvolume. The pH of seminal fluid also increased with an increase in viscosity (Hyperviscosity >Hypoviscosity). The pH of seminal fluid in patientswith less than 50% forward progressive movement of spermatozoa was higher when compared to those with more than 50% forwardprogressive movement. pH had an influence on the motility of spermatozoa. Conclusions and recommendation: pH and other parameterstended to have an influence each other during seminal analysis in our study. There is a variation of pH in different parts of the World according tothe studies done. It is recommended that pH should be included during seminal analysis because our study has shown that it affects most of theseminal fluid parameters in and contribute to the problem of infertility.

scholarly journals Time to improvement in semen parameters after microsurgical varicocelectomy in men with severe oligospermia

2018 ◽  
Vol 13 (3) ◽  
Author(s):  
Thomas A. Masterson ◽  
Aubrey B. Greer ◽  
Ranjith Ramasamy
Keyword(s):  
Semen Quality ◽  
Intrauterine Insemination ◽  
Sperm Count ◽  
Semen Analysis ◽  
Semen Parameters ◽  
Vitro Fertilization ◽  
Minimal Improvement ◽  
Quality Upgrading ◽  
Total Motile Sperm Count

Introduction: We aimed to determine the time and predictive factors of semen quality improvement in men with severe oligospermia after microsurgical varicocelectomy. Methods: Men with total motile sperm count (TMSC) <5 million on two semen analyses were identified from May 2015 to August 2017. Postoperative semen analysis was collected at 3–6 months and >6 months. We evaluated preoperative factors for successful semen quality upgrading based on assisted reproductive technology (ART) eligibility: in vitro fertilization [IVF] (<5 million), intrauterine insemination (IUI) (5–9 million), and natural pregnancy (>9 million). We compared men with TMSC <5 million to those with TMSC 5–9 million. Data are reported as means and standard error of the mean (SEM). Pregnancy data was collected by phone interview at >6 months postoperatively. Results: A total of 33 men were included. TMSC improved from 1.5±0.2 to 7.3±1.8 million at 3–6 months (p<0.05) and 12.2±3.6 million at >6 months (p<0.05). There was no statistical difference in TMSC between 3–6 months and >6 months. Sixteen (48.5%) men upgraded semen quality into the range of natural pregnancy. Preoperative TMSC from 2–5 million was predictive of upgrading semen quality. Twenty-four couples were contacted by phone; 20 were attempting pregnancy in the postoperative period and five (25%) of them had achieved natural pregnancy. Conclusions: Men with TMSC <5 million can expect the largest improvement in TMSC from 3–6 months postoperatively with minimal improvement thereafter. Preoperative TMSC >2 million was most predictive of semen quality upgrading.

scholarly journals The Impact of Intense Exercise on Semen Quality

2016 ◽  
Vol 11 (3) ◽  
pp. 654-662 ◽  
Author(s):  
Paweł Jóźków ◽  
Marco Rossato
Keyword(s):  
Physical Activity ◽  
Semen Quality ◽  
Sperm Count ◽  
Semen Analysis ◽  
Semen Parameters ◽  
Male Factor ◽  
Recreational Athletes ◽  
Increasing Demand ◽  
Male Reproductive Health ◽  
The Impact

With expanding knowledge on the health benefits of exercise, there is an increasing demand for information on the andrological consequences of participating in sports. These consequences are especially important in the context of infertility problems worldwide. The so-called “male factor” is reported in up to 50% of couples having trouble with conception. The answer to the question, “Is physical activity good for male reproductive health?” is not straightforward. A number of studies have suggested that significant changes in semen parameters may occur due to sports training of certain types, intensities, and durations. The changes to these parameters vary in scope, direction, and magnitude. Findings in recreational athletes have also differed from those in professional athletes. This review of the current literature suggests that intense physical activity may affect the semen concentration, as well as the number of motile and morphologically normal spermatozoa. Training at higher intensities and with increased loads seems to be associated with more profound changes in semen quality. In recreational athletes, exercise has either a positive or neutral effect on semen parameters. Due to many limitations (e.g., global sperm count trends, concerns about the quality control of sperm evaluations, and new standards for semen analysis), comparisons among historical data and their interpretation are difficult.

scholarly journals Bacteriospermia and Its Impact on Basic Semen Parameters among Infertile Men

2016 ◽  
Vol 2016 ◽  
pp. 1-6 ◽  
Author(s):  
Sangeetha Vilvanathan ◽  
Balan Kandasamy ◽  
Abiramy Lakshmy Jayachandran ◽  
Sarasa Sathiyanarayanan ◽  
Vijayalakshmi Tanjore Singaravelu ◽  
...  
Keyword(s):  
Staphylococcus Aureus ◽  
Semen Quality ◽  
Sperm Count ◽  
Semen Analysis ◽  
Surrogate Marker ◽  
Semen Parameters ◽  
Who Guidelines ◽  
E Coli ◽  
Infertile Men ◽  
Normal Sperm

Introduction. Semen analysis is considered as the surrogate marker for male fecundity while assessing infertile men. There are several reasons for altered semen quality and bacteriospermia could be one among them. Thereby the aim of our work is to study the semen culture and its impact on semen parameters among infertile men.Materials and Methods. Semen samples were collected from men attending infertility clinic. Semen parameters were analysed based on WHO guidelines. Also, samples were subjected to culture using standard bacteriological techniques.Results. A total of 85 samples were collected. A number of 47 (55.30%) had normal sperm count, 37 (43.50%) had oligozoospermia, and one (1.17%) had azoospermia. Teratozoospermia was the most common abnormality observed (81.17%) followed by asthenozoospermia (28.23%). The prevalence of bacteriospermia was 35.3%.Enterococcus faecalis(30%) was the most common organism isolated followed by Coagulase negativeStaphylococcus(23.33%),Staphylococcus aureus(20%), andE. coli(10%). Other less frequently isolated organisms wereKlebsiella pneumoniae(6.66%),Proteussp. (6.66%), andCitrobactersp. (3.33%).Conclusion. The presence of asymptomatic bacteriospermia did not correlate with abnormal semen parameters.

scholarly journals Ambient sulfur dioxide could have an impact on testicular volume from a observational study on a population of infertile male

BMC Urology ◽  
2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Yu-An Chen ◽  
Yi-Kai Chang ◽  
Yann-Rong Su ◽  
Hong-Chiang Chang
Keyword(s):  
Sulfur Dioxide ◽  
Semen Quality ◽  
Sperm Count ◽  
Environmental Pollutants ◽  
Sperm Concentration ◽  
Serum Testosterone ◽  
Testicular Volume ◽  
Semen Parameters ◽  
Negatively Associated ◽  
The Mean

Abstract Background The effect of ambient pollutants on the male reproductive system is controversial. This retrospective study investigated the effect of environmental pollutants on male reproductive health. Methods Male patients with primary infertility (n = 282) were identified from a single center between January 2016 and December 2017. Patients were physically examined for the presence of varicocele and for the volume of both testicles. Semen quality was measured in terms of the total sperm count, sperm concentration, and the percentage of sperm cells with motility and normal morphology. Data were acquired on the concentration of ambient pollutants, namely particulate matters of diameter < 2.5 μm, sulfur dioxide (SO2), nitrogen oxides (NOx), and ozone (O3), measured on daily and hourly basis, from the Environmental Protection Administration Executive Yuan, Taiwan. Individual exposure to pollutants was estimated based on the reported residential address of each participant. Statistical analysis indicated the effect of each pollutant on the testicular volume, sex hormone profile, and semen parameters. Results The mean ± standard deviation of age was 36.7 ± 7.3 years. The average sperm count and concentration were 41.9 million/mL and 34.1 million/mL, respectively. The mean levels of serum testosterone, follicle-stimulating hormone, and luteinizing hormone were 3.57 ± 1.68 ng/mL, 7.59 ± 6.3 IU/L, and 4.68 ± 3.49 IU/L, respectively. According to the multivariate linear regression model, NOx exposure was a risk factor for decreased sperm concentration and motility (p = 0.043 and 0.032). Furthermore, SO2 exposure was negatively associated and testicular volume (p < 0.01). Conclusions NO2 and SO2 exposure were negatively associated with the seminal parameter and decreased testicular volume, respectively, in a population of men with infertility. However, additional prospective studies are needed to ascertain the cause–effect relation of current results.

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