scholarly journals Study of Nail Changes in Psoriasis

2018 ◽  
Vol 29 (1) ◽  
pp. 29-32
Author(s):  
M Moksedur Rahman ◽  
M Abdullah ◽  
M Moazzem Hossain ◽  
MA Siddique ◽  
Moriom Nessa ◽  
...  

Psoriasis is a common, chronic and recurrent inflammatory disease of the skin. Clinically, disease can present with cutaneous and nail lesions. Both fingernails and toenails may be affected. The present study was conducted to study the abnormal nail changes in patients with psoriasis and to find correlation between nail changes and some clinical parameters. The study was undertaken in Skin & VD outpatient department of Rajshahi Medical College Hospital, Rajshahi. One hundred patients of psoriasis of all age and both sexes were enrolled for studying the nail changes, in whom diagnosis of psoriasis was made clinically. In any case of abnormalities clinically suspected of fungal infection, further mycological investigations were performed. Nail changes were present in 60 patients (60%, P<0.05) with psoriasis. Pitting was the most common finding on fingernails (70%), followed by onycholysis (35%). Subungual hyperkeratosis was the most common finding in toenails (34.37%). A very strong association was seen between nail changes and joint pain. There was positive correlation between nail abnormalities and duration of psoriasis. Nail involvement is common in patients with psoriasis. Pitting, onycholysis, subungual hyperkeratosis are the most frequent nail changes in psoriatic patients.TAJ 2016; 29(1): 29-32

KYAMC Journal ◽  
2018 ◽  
Vol 8 (2) ◽  
pp. 24-26 ◽  
Author(s):  
Md Moksedur Rahman ◽  
Md Abdullah ◽  
Moriom Nessa ◽  
Muhammad Afsar Siddiqui ◽  
Md Zillur Rahman ◽  
...  

Background: Psoriasis is a common, chronic and recurrent inflammatory disease of the skin. Clinically, disease can present with cutaneous and nail lesions. Both fingernails and toenails may be affected.Objectives: The present study was conducted to study the abnormal nail changes in patients with psoriasis and to find correlation between nail changes and some clinical parameters.Materials & Methods: The study was undertaken in Skin & VD outpatient department of Rajshahi Medical College Hospital, Rajshahi. One hundred patients of psoriasis of all age and both sexes were enrolled for studying the nail changes, in whom diagnosis of psoriasis was made clinically. In any case of abnormalities clinically suspected of fungal infection, further mycological investigations were performed.Results: Nail changes were present in 60 patients (60%, P<0.05) with psoriasis. Pitting was the most common finding on fingernails (70%), followed by onycholysis (35%). Subungual hyperkeratosis was the most common finding in toenails (34.37%). A very strong association was seen between nail changes and joint pain. There was positive correlation between nail abnormalities and duration of psoriasis.Conclusion: Nail involvement is common in patients with psoriasis. Pitting, onycholysis, subungual hyperkeratosis are the most frequent nail changes in psoriatic patients.KYAMC Journal Vol. 8, No.-2, Jan 2018, Page 24-26


2003 ◽  
Vol 7 (4) ◽  
pp. 317-321 ◽  
Author(s):  
Joanna Salomon ◽  
Jacek C. Szepietowski ◽  
Alina Proniewicz

Background: Psoriasis is a widespread skin disorder in which nail involvement is a common symptom. Many psoriatic patients have nail changes morphologically resembling onychomycosis. Objective: The present study was undertaken (1) to evaluate the frequency of nail involvement in psoriatic patients, (2) to assess the types of nail changes in psoriasis, (3) to find eventual relationships between nail involvement and some clinical parameters, and finally (4) to determine the prevalence of fungal nail infections in psoriatic individuals. Material and Methods: One hundred six patients hospitalized in our department due to exacerbation of psoriasis participated in the study. Each patient underwent dermatologic examination with special attention paid to the nail changes. In any case of abnormalities clinically suspected of fungal infection, further mycological investigations were performed. Results: Nail changes were present in 83 patients (78.3%) with psoriasis. The most common nail abnormality observed on both fingernails and toenails was subungual hyperkeratosis. Hyperkeratosis, onychorrexis, and discoloration of nail plates were observed significantly more often on toenails. Pitting and longitudinal ridges were significantly more frequent on fingernails. Patients with psoriatic nail dystrophy were significantly older than psoriatic patients without nail abnormalities. Nails were involved statistically more often in patients with arthropathic psoriasis. Positive mycological cultures were obtained from 18% of patients with nail changes. The most commonly isolated fungi were molds. Conclusions: Dystrophic nails are frequently found in psoriatic individuals, especially those suffering from arthropathic psoriasis. Subungual hyperkeratosis and pitting are the most typical lesions. It is difficult to assess definitively whether psoriasis is a predisposing factor to the development of fungal infections of the nails.


2020 ◽  
pp. 120347542098255
Author(s):  
Magdalena Żychowska ◽  
Małgorzata Żychowska

Background Lichen planus (LP) is an inflammatory condition that can affect skin, mucous membranes, hair follicles, and/or nails. Nail abnormalities are estimated to occur in around 10% of LP cases. Clinical characteristics of nail involvement have been the subject of very few studies, which have mainly focused on isolated nail LP. Objectives To identify and describe nail alterations in patients with LP. Methods Seventy-five patients with cutaneous lichen planus (CLP) were included in the study. The diagnosis of LP was histologically confirmed in each case. Onychomycosis was excluded in each patient. Results Nail lesions were present in 21 (28%) patients (mean age 58.1 ± 12.55 years) with CLP. On an average, patients had 9.38 nails affected. A slight female preponderance was noted (57%). Nail involvement was independent of age, gender, presence of pruritus, the affected skin area, or the duration of CLP. The most common finding in the fingernails ( n = 122) was longitudinal ridging (85.2%), followed by nail plate thinning (38.2%) and onycholysis (17.2%). Pterygium formation (6.6%) and red lunulae (8.2%) were limited to the fingernails. In the fingernails, matrix involvement (98.4%) was more frequent than nail bed involvement (27%). The most common finding in the toenails ( n = 75) was hyperkeratosis (82.7%) with yellowish discoloration (69.3%). No cases of trachyonychia or anonychia were noted. Conclusions Nail abnormalities in patients with CLP may be more common than initially assessed. Rare formation of pterygium and absence of anonychia in patients with predominant cutaneous involvement might point at mild course of the nail disease in such cases.


2018 ◽  
Vol 5 (2) ◽  
pp. 68-72 ◽  
Author(s):  
Shila Rani Das ◽  
Chinmay Biswas

Background: Medical students are in a huge pressure due to their academic syllabus. Objective: The purpose of the present study was to assess the relationship between anxiety and academic performance among private medical college.Methodology: This cross sectional study was done in private medical College Hospital, Dhaka, Bangladesh and 3rd and 4th year medical student were included. Data was   collected by using semi structured Socio-demographic questionnaire and Burn Anxiety Inventory scale and Checklist. Finally all data and results were analyzed using latest version of SPSS software. For descriptive statistics means, medians, SD and range will be calculated as required. Data will be presented in frequency table, bar, pie and scattered diagram as per need.  Statistical test chi-square test were used and p<0.05 was consider to be statistically significant.Results: A total number of 200 medical students were studied after fulfilling the inclusion and exclusion criteria. Among them 87.0% were Muslim; 98.0% were unmarried; 83.0% were in nuclear family; family member of 42.5% respondents had 4 to 6 persons; monthly income of 64.7% respondents were less than 50,000 Taka; 47.0% of the respondents’ father occupation was businessman. In 1st profession examination 68.0% in Anatomy, 73% in Physiology, 76% in Biochemistry were passed in anatomy. In 1st professional exam, students suffered from moderate to extreme anxiety were passed 78% and referred 22% as well as suffered from minimal to mild anxiety were passed 43% and referred 57% in Physiology. So there was strong association between the two variables (p<0.05).Conclusion: Three fifth of the students are suffered from moderate anxiety level and those who are suffered moderate to extreme anxiety passed more and their class attendance are good.Journal of Current and Advance Medical Research 2018;5(2):68-72


2016 ◽  
Vol 30 (2) ◽  
pp. 80-85 ◽  
Author(s):  
Sankar Kumar Basak ◽  
Kohinoor Begum ◽  
Maliha Rashid ◽  
Nahid Yasmin ◽  
Hasina Begum

Objective(s): To assess the association between the haematocrit value and severity of preeclampsia.Materials & Methods: This cross sectional study was conducted in the department of Obstetrics & Gynaecology of Dhaka Medical College Hospital, Dhaka during the period of January 2012 to December 2013. Total of 100 patients were studied and they were divided into two groups – group-A and group-B. Fifty preeclamptic patients were included in the group-A and 50 normal pregnant women were included in the group-B.Results: Majority of preeclamptic women (68%) and normal pregnant women (76%) were in the age group of 20-30 years with the mean ages of group-A and group-B subjects were 26.50±5.71 and 26.26±4.91 years respectively. Eighty six percent of group-A and 70% of group-B women were of lower socioeconomic status. Majority of the study subjects (74% of group-A and 80% of group-B) were housewife. More than half (54%) of the preeclamptic women were primigravid and 60% of normal pregnant women were multigravid. Among the preeclamptic subjects 16 (32%) had mild hypertension (DBP<110mmHg) and 34 (68%) had severe hypertension (DBP ? 110 mmHg). Out of 50 preeclamptic subjects 45 (90%) had severe proteinuria (+++) and only 5 (10%) had moderate (++) proteinuria.The mean haematocrit value of preeclamptic patients was 34.881±3.03 and that of normal pregnant women was 31.94±1.2. It was statistically significant (P value 0.001). The mean haematocrit value of normal pregnant, mild and severe preeclamptic women were 31.94±1.2, 33.31±2.57 and 35.62±2.95 respectively. It was also statistically significant (P value 0.001).Conclusion: This study shows that haematocrit value of preeclamptic patients is significantly higher compared to that of the normal pregnant women (P<0.05). There is a strong association of increasead haematocrit and preeclampsia.Bangladesh J Obstet Gynaecol, 2015; Vol. 30(2) : 80-85


2021 ◽  
Vol 29 (2) ◽  
pp. 100-105
Author(s):  
Joysree Saha ◽  
Sohana Siddique ◽  
Sumaya Akter ◽  
Md Abdul Quader ◽  
Indrajit Prasad ◽  
...  

Background: Ovarian tumors are a heterogeneous group of neoplasm that have become increasingly important now-a-days because of their large variety of neoplastic entities and gradually increased rate of mortality due to female genital cancers. Objectives: The aim of this study was to analyze the histopathological pattern and clinical presentation of malignant ovarian tumors according to the WHO classification of ovarian tumors [2003] in a tertiary care center of Dhaka, Bangladesh. Materials and Methods: This retrospective study included and studied a total of 54 cases of malignant ovarian tumors at the Department of Obstetrics and Gynecology, Popular Medical College Hospital, Dhaka, Bangladesh over a period of 3 years from Jan 2015 to Dec 2017. Results: The mean age was 47.44±14.24 years old (age ranged from 20-70 years). Of the 54 malignant ovarian tumors studied, the commonest histological pattern observed in the study was serous cyst adenocarcinoma constituting 26 cases (48.15%) followed by adenocarcinoma of ovary (25.9%), mucinous cyst adenocarcinoma (14.8%), endometriod adenocarcinoma (3.7%), dysgerminoma (3.7%) and ovarian choriocarcinoma (3.7%). High level of serum CA125 was found in most of the cases (n=48; 88.89%). The chief complaints were abdominal pain (n=38; 70.37%) and abdominal distension (n=29; 53.70%). Majority were admitted with less than one month duration of symptoms. The size of the tumor varied from 2.2 to 20 cm. All the patients were admitted in III and IV stage. Conclusions: Serous cyst adenocarcinoma was the common finding of this study. The prognosis and varying therapeutic strategies of malignant ovarian tumors necessitate an accurate histopathological evaluation. J Dhaka Medical College, Vol. 29, No.2, October, 2020, Page 100-105


KYAMC Journal ◽  
2021 ◽  
Vol 12 (1) ◽  
pp. 18-21
Author(s):  
Muntasir Mahbub ◽  
Md Mahbubur Rahman

Background: Hypertrophy of the adenoid is a common finding in children under 12 years of age, which commonly leads to impairment of hearing.Nasoendoscopyand audiological tests are frequently included in the workup of these patients. Objectives:Aim for this study was to find out whether any correlation exists between the size of adenoids on nasoendoscopy and the audiological parameters. Materials & Methods: This is cross-sectional study conducted from Jan 2019 to Jan 2020 in Khwaja Yunus Ali Medical College Hospital, Enayetpur, Shirajganj. Total 50 patients were included in this study. In all patients, Flexible nasoendoscopy, Pure tone audiometry and Tympanometry was done. Findings were evaluated to assess the correlation of degree of adenoid hypertrophy to the severity of hearing impairment. Results: In this study, mean age of participants was 7.46 (3.62) years. Findings of hypertrophy were – Grade I 7(13%), Grade II 24(47%), Grade III 14(28%), Grade IV 6(12%).Findings of hearing status were – upto 25 dB 14(28%), Between 26–40 dB 32(64%), Above 40 dB 4(8%). Mean hearing loss according to adenoid hypertrophy were – Grade I –19.42dB, Grade II –30.41dB, Grade III – 35.64dB, Grade IV – 38.60dB. Type B curve percentage on adenoid groups were – Grade I – 3(43%), Grade II – 16(67%), Grade III – 11(79%), Grade IV – 6(100%). Conclusion: Adenoid hypertrophy as seen on nasoendoscopy correlates well with the expected audiological parameters in children. KYAMC Journal.2021;12(01): 18-21


2018 ◽  
Vol 4 (2) ◽  
pp. 129-132
Author(s):  
Nadira Khan ◽  
Firoza Rahman ◽  
Nilufar Jahan ◽  
Rahela Khatun ◽  
Nebadita Saha

Background: Pelvic Inflammatory disease is presented with different clinical presentation among the sexually active women.Objectives: The purpose of the present study was to see the clinical profiles of women presented with pelvic inflammatory diseases.Methodology: This cross-sectional study was carried out in the Department of Obstetrics and Gynaecology at Dhaka Medical College Hospital, Dhaka, Bangladesh from November 2001 to April 2002 during the period of six (06) months and December 2002 to February 2003 for three (03) months with the total duration of nine (09) months. Women at any age who were suffering from chronic pelvic inflammatory disease (PID) attended at the OPD of gynecology Department at Dhaka Medical College Hospital, Dhaka, Bangladesh were selected as study population. Epidemiological aspects and clinical presentation have been mainly highlighted in this study.Result: A total number of 150 cases were recruited for this study. Among 150 case of chronic pelvic inflammatory disease (PID) majority of the patients (54%) belonged to the age group of 26 to 35 years of age group followed by 16 to 25 years which was 33.3% cases. Majority 96.0% patients had pain in the lower abdomen; 78.6% cases had backache; 76.6% cases had dyspareunia; 64.0% had congestive dysmenorrhea and 60.0% cases had vaginal discharge. Regarding menstrual problems, 72.7% cases had dysmenorrhea. Majority (84.0%) cases were multipara.Conclusion: In conclusion lower abdominal pain, backache, dyspareunia, congestive dysmenorrhea are the major complaints among the PID patients.Journal of National Institute of Neurosciences Bangladesh, 2018;4(2): 129-132


2019 ◽  
Vol 16 (2) ◽  
pp. 65-69
Author(s):  
Nadira Khan ◽  
Firoza Rahman ◽  
Nilufar Jahan ◽  
Rahela Khatun ◽  
Shafeya Khanam

Background: Pelvic Inflammatory disease is a very common gynaecological condition among the women. Objectives: The purpose of the present study was to see the obstetrics factors related with the pelvic inflammatory disease. Methodology: This cross-sectional study was carried out in the Department of Obstetrics and Gynaecology at Dhaka Medical College Hospital, Dhaka, Bangladesh from November 2001 to April 2002 during the period of six (06) months and December 2002 to February 2003 for three (03) months with the total duration of nine (09) months. Women in child bearing age who were suffering from chronic pelvic inflammatory disease (PID) attended at the OPD of gynecology Department at Dhaka Medical College Hospital, Dhaka, Bangladesh were selected as study population. Relevant data from each patient were recorded in a questionnaire. Result: A total number of 150 cases were studied. Out of 146 patients 75.3% were delivered at home, 8.2% at hospital and 16.4% cases had their deliveries at home and at hospital also. Out of 146 patients 63.0% were delivered by untrained birth attendants at home and 36.99% were delivered by trained birth attendants. Out of 146 patients 54.1% had history of puerperal sepsis. However, the rest of the 67(45.9%) cases were normal puerperium. In this study 84.0% patients had history of MR, 18 percent had spontaneous abortion and 4.7 percent had induced abortion. Out of these 115 patients with history of pregnancy termination, 47.3% patients had history of pelvic infection following that event. Also, 2.7% gave history of ectopic pregnancy. Conclusion: In conclusion most of the PID patients are delivered at home with untrained birth attendants with the history of puerperal sepsis Journal of Science Foundation 2018;16(2):65-69


2016 ◽  
Vol 11 (1) ◽  
pp. 20-22
Author(s):  
Md Towhid Alam ◽  
Shakh Abdul Fattah ◽  
MM Shahin Ul Islam ◽  
Md Anisur Rahman Howlader ◽  
Ahmed Manadir Hossain ◽  
...  

Significant number of Encephalitis patient was admitted in Faridpur Medical College Hospital (FMCH) in last years. There was an outbreak of Nipah Virus encephalitis in Faridpur in 2004. Among the 34 cases 26 patients were expired. After that, occurrence of disease is continuing. In this study a total number of 100 cases of clinically suspected encephalitis patients were studied for different clinical parameters and observed their clinical outcome. This is a retrospective study using data from hospital records. Among them 62% were male and 38% were female. Largest numbers of patients were under age group of 21-35 years, 46% of patients were from Faridpur district then 24% from Rajbari. Majority of patients were presented with neurological features (74%), 10% with pulmonary, 4% gastrointestinal, rest 12 % with combined neurological and pulmonary features. Maximum numbers (30%) of patients were attained treatment within 25 to 48 hours of onset of symptoms. Among them 78% of the patients recovered, 17% expired and 5% were referred. In this context, further prospective study is required to find out the epidemiological characteristics of Encephalitis in Faridpur region.Faridpur Med. Coll. J. Jan 2016;11(1): 20-22


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