scholarly journals Comparison of efficacy of Ledermix and Calcium hydroxide in the management of deep caries

2020 ◽  
Vol 10 (1) ◽  
pp. 6-12
Author(s):  
Fahd AA Karim ◽  
Asma Sultana ◽  
Hanann Shiekh ◽  
Md Ashif Iqbal ◽  
Puja Shrestha ◽  
...  
Keyword(s):  
Calcium Hydroxide ◽  
Permanent Teeth ◽  
Protective Agent ◽  
Pulp Capping ◽  
Conservative Dentistry ◽  
Group 2 ◽  
One Year ◽  
And Function ◽  
Indirect Pulp Capping

Background:Pulp capping is a treatment that enables pulp to recover and maintain its vitality and function by applying a protective agent to an exposed pulp. Ca (OH)2 has been considered the gold standard for this procedure. Despite its wide use, Ca (OH)2 is not ideally suited for pulp capping. Recently ledermix cement used for indirect pulp capping material in the outer world broadly. Objective: To assess the clinical and radiological evidence of the formation of secondary dentin and compare the degree of short time post operating pain after indirect pulp treatment. Methods: A Randomized control trial in vivo study was directed in the Department of Conservative Dentistry and Endodontics, Faculty of Dentistry, Bangabandhu Sheikh Mujib Medical University for one year (January 2012-January 2013). We took the patients with 40 deep carious permanent teeth as a sample. The selected teeth were divided into two test groups. All odd number teeth (20) were included in group-1(where pulp capping was done with ledermix cement). All even number teeth (20) were included in group-2(where pulp capping was done with Ca(OH)2). We assessed all the patients clinically and radiographically at the interval of 3, 6, and 12 months simultaneously for the assessment of dentinal bridge formation and also collected data was analyzed using statistical package for social science (SPSS) version 17. Results: Among the full scale 40 models, ledermix (20) and Ca(OH)2(20), minor to direct irritaion of the teeth was experienced premium to treatment and found comparable in the two gatherings. Regardless, after 24 hrs of treatment, this value was shockingly higher in the Ca(OH)2 (p<0.01)group than in the Ledermix gathering (p < 0.001, t-test). Following 7 days, there was no basic differentiation between them. Follow up evaluation revealed, failure of 3 teeth treated with Ca(OH)2 and 2 teeth treated with ledermix due to pain and swelling. The remaining 35 teeth radiated an impression of being clinically and radiologically successful a year postoperatively. Conclusion: No post-operative pain was experienced in both groups in the long term. However, within the first hours after cementation, there was a sensation of pain significantly higher in the Ca(OH)2 group than in the Ledermix group. Ledermix can be considered a predictable treatment and may be an alternative to calcium hydroxide in indirect pulp capping. Update Dent. Coll. j: 2020; 10 (1): 6-12

scholarly journals Evaluation of clinical and radiological outcomes of mineral trioxide aggregate and calcium hydroxide as indirect pulp capping agents in the treatment of deep carious lesion of permanent teeth

2016 ◽  
Vol 9 (3) ◽  
pp. 140 ◽  
Author(s):  
Rafeza Sultana ◽  
Mozammal Hossain ◽  
Md. Shamsul Alam
Keyword(s):  
Calcium Hydroxide ◽  
Mineral Trioxide Aggregate ◽  
Permanent Teeth ◽  
Capping Agents ◽  
Pulp Capping ◽  
Carious Lesions ◽  
Reparative Dentin ◽  
Deep Carious Lesions ◽  
Pulp Vitality ◽  
Indirect Pulp Capping

<p>The maintenance of pulp vitality and conduction of reparative dentin can be possible by indirect pulp capping with mineral trioxide aggregate (MTA) and calcium hydroxide as pulp capping agents. The objective of the study is to assess the clinical and radiological outcomes of MTA and calcium hydroxide as indirect pulp capping agents in deep carious lesions of permanent teeth. The present study included 50 permanent teeth having deep carious lesions with reversible pulp status were selected and then randomly divided into two groups of 25 teeth in a group. Standard indirect pulp capping procedures were followed. Patients were recalled at 3, 6 and 12 months interval to assess postoperative pain, the vitality of the pulp and formation of reparative dentin. In all observation periods, MTA showed more capable of reducing pain and maintain pulp vitality which was statistically significant than that of calcium hydroxide. At 12 months observation period, 24 teeth (96%) of MTA and 19 teeth (76%) of calcium hydroxide showed reparative dentin formation. It can be concluded that MTA is more effective than that of calcium hydroxide.</p><p> </p>

scholarly journals A Retrospective Analysis of The Correlation Between the Type of Pulp Exposure and The Choice of Pulp Capping Agents

2020 ◽  
Vol 11 (SPL3) ◽  
pp. 901-906
Author(s):  
Vignesh S ◽  
Iffat Nasim ◽  
Arvina Rajasekar
Keyword(s):  
Dental Caries ◽  
Calcium Hydroxide ◽  
Total Sample ◽  
Direct Pulp Capping ◽  
Chi Square ◽  
Pulp Capping ◽  
Conservative Dentistry ◽  
Chi Square Test ◽  
Pulp Exposure ◽  
Indirect Pulp Capping

The aim was mainly to determine the correlation between the type of pulp capping method and the material of choice in this study. Pulp capping in the carious teeth has been considered as unpredictable and they mainly have a lesser success rate. The pulp capping can be mainly done in two methods; they are direct and indirect pulp capping which can be mainly done with the help of different materials of choice like calcium hydroxide,MTA etc. The study was conducted in Saveetha Dental College . The data collection has been done from the department of Conservative dentistry and Endodontics for patients undergoing pulp capping treatment. A total sample data of 140 patients were obtained for a period of nine months ( June 2019 – April 2020.). Statistical analysis was done by using chi-square test with SPSS software version 23. The results were obtained and tabulated, the type of pulp capping method were 67% of indirect pulp capping and 33% of direct pulp capping method in which 81% of calcium hydroxide, 8% of MTA and 11% of RMGIC was used as the materials of choice. Among which indirect pulp capping method was most commonly used than the direct pulp capping method with calcium hydroxide as the material of choice for the treatment (p < 0.05 which is statistically significant).   The pulpal exposure was mainly due to the dental caries and mechanical preparation of the tooth. Within the limits of the present study, the most common type of the pulp exposure was due to the dental caries and mechanical exposure during the cavity preparation of the tooth and the most common method of pulp capping was the indirect method with calcium hydroxide (CaOH) as the most common material of choice.

scholarly journals Microbiological Findings in Deep Caries Lesions

2016 ◽  
Vol 63 (1) ◽  
pp. 7-14 ◽  
Author(s):  
Irena Kuzmanović Radman ◽  
Aleksandra Djeri ◽  
Adriana Arbutina ◽  
Jelena Milašin
Keyword(s):  
Calcium Hydroxide ◽  
Bacterial Species ◽  
Permanent Teeth ◽  
Microbiological Analysis ◽  
Oral Diseases ◽  
Pulp Capping ◽  
Carious Lesions ◽  
Deep Carious Lesions ◽  
Caries Lesions ◽  
Indirect Pulp Capping

SUMMARY Introduction Caries is one of the most significant and widespread oral diseases. It has been confirmed that dental plaque, i.e. microorganisms in it, are the most important factor in the development of dental caries. Caries profunda represents deep carious lesion from where bacterial toxins may affect pulp through dentinal tubules. The aim of this study is to assess the efficacy of indirect pulp capping based on microbiological findings of bacteria present in deep carious lesions before and after the treatment. Material and Methods The clinical study included 29 patients of both genders, aged 16 to 40 and 45 permanent teeth with deep caries lesions. The first microbiological sample was taken after cavity preparation and removal of soft dentin from the bottom of the cavity. The second sample was taken after the removal of temporary filling and calcium hydroxide paste 60 days after the indirect pulp capping treatment. The collected samples were stored in special sterile micro tubes (Eppendorf) and kept at the temperature of −80°C until microbiological analysis was performed. Samples were tested for the presence of the following microorganisms: Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans and Enterococcus faecalis using the multiplex polymerase chain reaction (PCR) method. Results The results showed that prior to the treatment of deep carious lesions the most common species was E. faecalis (80% of samples), followed by A. actinomycetemcomitans (32% of samples), while the least common was P. gingivalis (16% of samples). After the treatment with products based on calcium hydroxide, E. faecalis was registered in 18% of samples, A. actinomycetemcomitans in 16% of samples and P. gingivalis was not registered in any sample. Conclusion The most common bacterial species in teeth with deep caries lesions was E. faecalis, whereas A. actinomycetemcomitans and P. gingivalis were found in lower number of samples.

COMPARATIVE EVALUATION OF ANTIMICROBIAL ACTIVITY OF CALCIUM HYDROXIDE AND SILVER NANOPARTICLES AS INTRACANAL MEDICAMENT: AN IN-VIVO STUDY

2021 ◽  
pp. 13-15
Author(s):  
Aditi Kohli ◽  
Rakesh Mittal ◽  
Monika Tandan
Keyword(s):  
Antimicrobial Activity ◽  
Silver Nanoparticles ◽  
Calcium Hydroxide ◽  
Wilcoxon Test ◽  
Permanent Teeth ◽  
Working Length ◽  
Intergroup Comparison ◽  
Group 2 ◽  
Group 1

The aim of this study was to evaluate and compare the antimicrobial activity of calcium hydroxide and silver nanoparticles as an intracanal medicament in patients with necrotic/infected pulp. Materials And Methods– 30 single rooted permanent teeth diagnosed clinically and radiographically with necrotic/infected pulp were included. After complete disinfection, access opening was done and working length was determined. The rst microbiological pre-treatment sample (S1) was collected by paper points. After completion of instrumentation, a post-instrumentation sample (S2) was taken and the teeth were divided into two groups: Group 1: calcium hydroxide, Group 2: Silver nanoparticles. The intracanal medicaments were left in place for 7 days. Post 1 week, S3 was taken. Samples collected were cultured on BHI agar and colony forming units were counted after 24 hours. Results- Intergroup comparison was done using Mann Whitney U test & intragroup comparison was done using Friedman test & Wilcoxon test. It was observed that the percentage reduction was better with Group 2 (Silver nanoparticles), however, it was not statistically signicant when compared to Group 1 (Calcium hydroxide). Conclusion – It was concluded that silver nanoparticles showed signicant antimicrobial activity and can be used as an effective root canal medicament as an alternative to calcium hydroxide dressing.

Osseointegration interface of calcified bone and endosseous implants

1992 ◽  
Vol 50 (2) ◽  
pp. 1096-1097
Author(s):  
K.E. Krizan ◽  
J.E. Laffoon ◽  
M.J. Buckley
Keyword(s):  
Structure And Function ◽  
Titanium Implants ◽  
En Bloc ◽  
Endosseous Implants ◽  
Ultrastructural Studies ◽  
The Past ◽  
Cacodylate Buffer ◽  
One Year ◽  
And Function

With increase use of tissue-integrated prostheses in recent years it is a goal to understand what is happening at the interface between haversion bone and bulk metal. This study uses electron microscopy (EM) techniques to establish parameters for osseointegration (structure and function between bone and nonload-carrying implants) in an animal model. In the past the interface has been evaluated extensively with light microscopy methods. Today researchers are using the EM for ultrastructural studies of the bone tissue and implant responses to an in vivo environment. Under general anesthesia nine adult mongrel dogs received three Brånemark (Nobelpharma) 3.75 × 7 mm titanium implants surgical placed in their left zygomatic arch. After a one year healing period the animals were injected with a routine bone marker (oxytetracycline), euthanized and perfused via aortic cannulation with 3% glutaraldehyde in 0.1M cacodylate buffer pH 7.2. Implants were retrieved en bloc, harvest radiographs made (Fig. 1), and routinely embedded in plastic. Tissue and implants were cut into 300 micron thick wafers, longitudinally to the implant with an Isomet saw and diamond wafering blade [Beuhler] until the center of the implant was reached.

Decision-Making and Management of Immature Permanent Teeth with Crown Fractures in Small Animals—A Review

2021 ◽  
pp. 089875642110463
Author(s):  
Amalia Zacher ◽  
Sandra Manfra Marretta
Keyword(s):  
Treatment Options ◽  
Mineral Trioxide Aggregate ◽  
Permanent Teeth ◽  
Small Animals ◽  
Unique Challenge ◽  
Pulp Capping ◽  
Pulp Therapy ◽  
Vital Pulp Therapy ◽  
Pulp Vitality ◽  
And Function

Immature permanent teeth with crown fractures present a unique challenge in human and animal patients. Immature permanent teeth have not yet developed completely, often presenting with thin dentin walls, incomplete apical formation, and increased crown-to-root ratios. Loss of pulp function at this stage has devastating long-term implications for these teeth. Ideally, attempts should be made to preserve pulp vitality in immature permanent teeth to allow for continued dental development. The range of treatment options for vital teeth includes odontoplasty with bonding and sealing +/− restoration, indirect pulp capping, and direct pulp capping/vital pulp therapy. These treatments have long been established in human and veterinary medicine, and cases have been reported in dogs and cats. Apexification using calcium hydroxide is a well-established treatment for nonvital immature teeth. The advent of mineral trioxide aggregate and other bioceramic materials for use in vital pulp therapy and apexification has reduced treatment sessions and improved outcomes. Recent developments in the field of regenerative endodontic therapy further expand treatment options and provide the possibility for continued development of a formerly nonvital tooth. Selecting the appropriate treatment based on the severity of tooth fracture and status of pulp vitality can avoid a lifetime of poor structure and function for the affected tooth. This article provides multiple step-by-step protocols for the management of immature permanent teeth with crown fractures in small animals.

scholarly journals Activation of group 2 innate lymphoid cells alleviates aging-associated cognitive decline

2020 ◽  
Vol 217 (4) ◽  
Author(s):  
Ivan Ting Hin Fung ◽  
Poornima Sankar ◽  
Yuanyue Zhang ◽  
Lisa S. Robison ◽  
Xiuli Zhao ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Innate Lymphoid Cells ◽  
Lymphoid Cells ◽  
Brain Physiology ◽  
Aged Brain ◽  
Group 2 ◽  
Resident Group ◽  
And Function

Increasing evidence has challenged the traditional view about the immune privilege of the brain, but the precise roles of immune cells in regulating brain physiology and function remain poorly understood. Here, we report that tissue-resident group 2 innate lymphoid cells (ILC2) accumulate in the choroid plexus of aged brains. ILC2 in the aged brain are long-lived, are relatively resistant to cellular senescence and exhaustion, and are capable of switching between cell cycle dormancy and proliferation. They are functionally quiescent at homeostasis but can be activated by IL-33 to produce large amounts of type 2 cytokines and other effector molecules in vitro and in vivo. Intracerebroventricular transfer of activated ILC2 revitalized the aged brain and enhanced the cognitive function of aged mice. Administration of IL-5, a major ILC2 product, was sufficient to repress aging-associated neuroinflammation and alleviate aging-associated cognitive decline. Targeting ILC2 in the aged brain may provide new avenues to combat aging-associated neurodegenerative disorders.

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