The Value of Cardiovascular Risk Factors in Predicting Hearing Recovery of Sudden Sensorineural Hearing Loss

AbstractObjective:To evaluate the presence of cardiovascular risk factors and recovery of idiopathic sudden sensorineural hearing loss in hospitalised patients.Methods:A single-centre retrospective study of 80 patients hospitalised for idiopathic sudden sensorineural hearing loss was conducted over a 6-year period. Mean pure tone hearing thresholds were assessed by pure tone audiometry.Results:Twenty-three of 80 patients (28.75 per cent) initially had no cardiovascular risk factors. Forty-five patients had hyperlipidaemia, 22 patients had hypertension, 7 patients had diabetes mellitus and 7 patients were obese. No statistically significant difference was observed between patients with complete versus partial sudden sensorineural hearing loss (p = 0.0708) concerning the cardiovascular risk factors. At long-term follow up, the hearing recovery rate was not significantly different between the two groups of patients (p = 0.7541).Conclusion:The lack of a clear relationship between idiopathic sudden sensorineural hearing loss and cardiovascular risk factors suggests that sudden sensorineural hearing loss has a predominantly multifactorial disease profile regardless of hearing impairment severity.

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Serum Fatty Acids and Cardiovascular Risk Factors in Sudden Sensorineural Hearing Loss: A Case-Control Study

Annals of Otology Rhinology & Laryngology ◽

10.1177/000348941011900203 ◽

2010 ◽

Vol 119 (2) ◽

pp. 82-88 ◽

Cited By ~ 21

Author(s):

Gabriella Cadoni ◽

Alessandro Scorpecci ◽

Francesca Cianfrone ◽

Sara Giannantonio ◽

Gaetano Paludetti ◽

...

Keyword(s):

Risk Factors ◽

Fatty Acids ◽

Hearing Loss ◽

Cardiovascular Risk ◽

Sensorineural Hearing Loss ◽

Cardiovascular Risk Factors ◽

Case Control Study ◽

Case Control ◽

Sudden Sensorineural Hearing Loss ◽

Control Study

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Clinical Profile of Patients With Unilateral Sudden Sensorineural Hearing Loss: Correlation With Hearing Prognosis

Otolaryngology ◽

10.1177/0194599820986571 ◽

2021 ◽

pp. 019459982098657

Author(s):

Adriana Perez Ferreira Neto ◽

Rafael da Costa Monsanto ◽

Line Dore Saint Jean ◽

Lucas Sonzzini Ribeiro de Souza ◽

Norma de Oliveira Penido

Keyword(s):

Risk Factors ◽

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Odds Ratio ◽

Univariate Analysis ◽

Sudden Sensorineural Hearing Loss ◽

Sensorineural Hearing ◽

Profound Hearing Loss ◽

Hearing Recovery ◽

Independent Risk Factors

Objective To characterize, with a standard systematic protocol, the clinical and audiometric profile of patients with idiopathic sudden sensorineural hearing loss (ISSNHL) and to correlate the findings with hearing recovery prognosis. Study Design Retrospective cohort of patients with ISSNHL. Setting Outpatients of a tertiary referral center followed for 20 years. Methods We collected clinical information, including the presence of tinnitus, vertigo, and comorbidities, as well as initial pure tone averages, degree of hearing loss, audiogram curves, and time between hearing loss onset and treatment. These variables were statistically analyzed for their impact on hearing recovery prognosis. All patients were treated with oral corticosteroids, following a standard treatment protocol. Hearing recovery was defined according to the criteria of the American Academy of Otolaryngology–Head and Neck Surgery Foundation, and hearing outcomes were reported via a standardized method (scattergrams). Results Our final study group comprised 186 patients. Most patients were between 41 and 60 years of age. Univariate analysis revealed that vertigo; presence of severe or profound initial hearing loss; flat, U-shaped, and descending audiogram curves; and initiating treatment ≥15 days were correlated with worse hearing recovery. However, the multivariate logistic model revealed that only the presence of severe or profound hearing loss (odds ratio, 6.634; 95% CI, 2.714-16.216; P < .001) and initiating treatment ≥15 days (odds ratio, 0.250; 95% CI, 0.102-0.610; P = .008) were independent risk factors for worse hearing recovery prognosis. Conclusion This study demonstrated that the presence of severe or profound hearing loss at the first audiogram and initiating treatment after 14 days from ISSNHL onset were independent risk factors associated with a worse hearing recovery prognosis.

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Comorbid Benign Paroxysmal Positional Vertigo in Idiopathic Sudden Sensorineural Hearing Loss: An Ominous Sign for Hearing Recovery

Yearbook of Neurology and Neurosurgery ◽

10.1016/j.yneu.2012.04.051 ◽

2012 ◽

Vol 2012 ◽

pp. 135-136

Author(s):

A. Minagar

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Benign Paroxysmal Positional Vertigo ◽

Sudden Sensorineural Hearing Loss ◽

Sensorineural Hearing ◽

Positional Vertigo ◽

Hearing Recovery ◽

Paroxysmal Positional Vertigo

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Effectiveness of Various Treatments for Sudden Sensorineural Hearing Loss—A Retrospective Study

Life ◽

10.3390/life12010096 ◽

2022 ◽

Vol 12 (1) ◽

pp. 96

Author(s):

Magdalena B. Skarżyńska ◽

Aleksandra Kołodziejak ◽

Elżbieta Gos ◽

Milaine Dominici Sanfis ◽

Piotr H. Skarżyński

Keyword(s):

Hearing Loss ◽

Sensorineural Hearing Loss ◽

Success Rate ◽

Complete Recovery ◽

Sudden Onset ◽

Sudden Sensorineural Hearing Loss ◽

Sensorineural Hearing ◽

Prolonged Treatment ◽

Retrospective Clinical Study ◽

Hearing Recovery

(1) Background: A retrospective clinical study was conducted to compare the effectiveness of different pharmacological and non-pharmacological regimens for treating sudden sensorineural hearing loss (SSNHL). (2) Methods: Adult patients (n = 130) diagnosed with sudden sensorineural hearing loss (SSNHL) and hospitalized between 2015 and 2020 were enrolled in this study. Depending on the treatment regimen applied, patients were divided into five groups. Inclusion criteria were as follows: (i) hearing loss of sudden onset; (ii) hearing loss of at least 30 dB at three consecutive frequencies; (iii) unilateral hearing loss; (iv) age above 18 years. Exclusion criteria were as follows: (i) no follow-up audiogram; (ii) bilateral hearing loss; (iii) recognized alternative diagnosis such as tumor, disorder of inner ear fluids, infection or inflammation, autoimmune disease, malformation, hematological disease, dialysis-dependent renal failure, postdural puncture syndrome, gene-related syndrome, mitochondrial disease; and (iv) age below 18 years. (3) Results: Complete recovery was found in 14% of patients (18/130) and marked improvement was found in 6% (8/130), giving an overall success rate of 20%. The best results were obtained in the second group (i.e., patients given intratympanic glucocorticoid + prolonged orally administered glucocorticoid) where the success rate was 28%. In general, the older the patient, the smaller the improvement in hearing, a correlation that was statistically significant. (4) Conclusions: In treating SSNHL, the highest rate of hearing recovery—28%—was in the group of patients given intratympanic corticoid plus prolonged treatment with orally administered glucocorticoid.

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