Recurrent Miscarriage and Consanguinity among Omani Women– A Cross Sectional Study

Objective: to determine the prevalence of explained and unexplained recurrent miscarriages (RM) and to find out if there is a significant relationship between recurrent miscarriages and consanguinity. Methods: A cross sectional in which the cases group included all women with RM attending the outpatient clinic at Sultan Qaboos University Hospital from July 2006 to April 2012 and the controls group included women with no history of RM after matching them with cases for age (case to control ratio was 1:1). The main outcome measures were the prevalence of consanguinity in women with or without recurrent miscarriages. Results: During study period a total of 290 women with RM were seen. Of which, 150 (51.7%) women had unexplained RM. Control group with no history of RM were 300 women. Consanguinity rate among cases (49.5%) %) was less than the controls (52.7 %%). Both first cousin and second cousin marriages were more common in the controls than the cases and it was not statistically significant (p value 0.476, chi squared test). Conclusion: In this study we found that more than half of RM cases were unexplained and there was no significant association between RM and consanguinity.

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CELIAC DISEASE

The Professional Medical Journal ◽

10.29309/tpmj/2015.22.01.1414 ◽

2015 ◽

Vol 22 (01) ◽

pp. 072-075

Author(s):

Sana Zulfiqar ◽

Amin Fahim ◽

Aneela Qureshi ◽

Sadia Adnan ◽

Shomail Saeed Siddiqui ◽

...

Keyword(s):

Celiac Disease ◽

Histopathological Examination ◽

Duodenal Mucosa ◽

Cross Sectional Study ◽

University Hospital ◽

P Value ◽

Cross Sectional ◽

Marsh Type ◽

History Of ◽

And Gender

Objective: To find out the Modified Marsh type of celiac disease (CD)patients on histopathological examination of duodenal (D2) biopsies and to correlate it withtissue transglutaminase IgA levels. Study Design: Cross sectional study. Place of Study:Histopathology laboratory (Department of Pathology), Isra University Hospital and AsianInstitute of Medical Sciences (AIMS), Hyderabad. Duration of Study: July 2013 to December2013. Materials and Methods: 96 patients with a history of malabsorption or atypical symptomswith clinical suspicion of CD were subjected to endoscopy. Endoscopic duodenal (D2) biopsieswere taken regardless of age and gender. D2 biopsies were processed for histopathologicalexamination under light microscopy. Results: Out of 96 patients, 45 (46.9%) patients hadmoderate type of lamina propria inflammation along with highly significant p-value (0.0001).CDtype 3a was observed in 34 patients (35.4%). In this study the comparison of serological level oftissue Transglutaminase IgA (tTGA) and histological severity revealed significant correlation. AllModified Marsh types of CD with tTGA level seen in our study were highly significant (p-value0.001). Conclusion: In this study strong correlation was observed between the serologicaltTGA level and histological findings by Modified Marsh classification along with lamina propriainflammation of duodenal mucosa in CD patients.

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Association between physical activity and hypertension: A retrospective study

10.21203/rs.3.rs-48088/v1 ◽

2020 ◽

Author(s):

Zhengyao Hou ◽

Shaoping Wan ◽

Zhengping Yong ◽

Yu Wu ◽

Yueqi Zhang ◽

...

Keyword(s):

Physical Activity ◽

Missing Values ◽

Cross Sectional Study ◽

Rank Test ◽

P Value ◽

Moderate Activity ◽

Cross Sectional ◽

Chi Squared ◽

History Of ◽

Working Day

Abstract Background: Many guidelines recommend physical activity to prevent hypertension. However, the recommendations of different studies and guidelines for physical activity to prevent hypertension are not uniform. The objective of this study is to examine the association between the prevalence of hypertension and physical activity in different patterns, intensities, and durations. Methods: The sample was from a cross-sectional study of 479,842 subjects called the China Hypertension Survey, 2012-2015. We selected participants with physical activity information from the survey results in Sichuan Province (n = 19,277) for this study. As an advantage of our research, we used multiple imputation to supplement the missing data, instead of mean filling or delete missing values directly. The relationship between physical activity and hypertension was mainly analyzed by the Wilcoxon rank-test, Chi-squared tests, and the logistic regression model. Results: There were 2,006 participants eligible. A total of 354 (17.6%) participants were hypertensive. Participants who were older, less educated, had higher BMI, used alcohol regularly, and had a family history of hypertension were more likely to get hypertension (p-value<0.0001). Both walking or cycling ≥ 15 hours/week (OR = 0.58; 95% CI = 0.36-0.95) and the sleeping duration ≥ 10 hours/non-working day (OR = 0.40; 95% CI = 0.19-0.81) are related to the low prevalence of hypertension. The risk factor associated with hypertension is the moderate activity related to leisure ≥ 15 hours/week (OR = 1.98; 95% CI = 1.14-3.40). Conclusions: This study indicates that there is a significant association between the duration of physical activity and the prevalence of hypertension. Moreover, this association is affected by different patterns of physical activity.

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Attitudes Towards Cancer Patients

Sultan Qaboos University Medical Journal [SQUMJ] ◽

10.18295/squmj.2021.21.02.010 ◽

2021 ◽

Vol 21 (2) ◽

pp. e221-230

Author(s):

Mohammed Al-Azri ◽

Fahad Al-Hattali ◽

Humaid Al-Ghafri ◽

Sathiya M Panchatcharam

Keyword(s):

Cancer Patients ◽

Cross Sectional Study ◽

University Hospital ◽

Cross Sectional ◽

Sultan Qaboos University ◽

Supportive Environment ◽

Social Difficulties ◽

History Of ◽

Keywords Cancer ◽

Patients Experience

Objectives: Many cancer patients experience social difficulties and feelings of isolation. This study aimed to evaluate patients’ and attendees’ attitudes towards cancer patients. Methods: A cross-sectional study was conducted of patients and attendees attending Sultan Qaboos University Hospital (SQUH), Muscat, Oman, from December 2018 to March 2019. Results: A total of 1,190 people participated (response rate: 91.5%). The majority (90.7%) did not express reluctance to help cancer patients. Most agreed that cancer patients were productive (76.2%) and are respected by the public (75.0%). However, many participants (63.1%) felt that cancer patients might face difficulties getting married. Multivariate analysis showed that participants who had a family history of cancer or had previously been a caregiver for cancer patients were more likely to believe that cancer patients could be productive (odds ratio [OR] = 1.92, 95% confidence interval [CI]: 1.31–2.82; P <0.05). Less-educated participants were more likely to believe that cancer patients feared not being productive (OR = 1.49, 95% CI: 1.01–2.19; P <0.05). Male and single participants were more likely to perceive that cancer patients faced difficulties getting married (OR = 1.56, 95% CI: 1.20–2.02 and OR = 1.68, 95% CI: 1.22–2.32, respectively; P <0.05 each). Conclusion: Patients and attendees attending SQUH in Oman appeared to have positive and supportive attitudes towards cancer patients, although some felt that cancer patients might encounter social obstacles. Healthcare professionals should consider reassuring cancer patients of such positive sentiments. Governmental and non-governmental organisations should act to promote a supportive environment for cancer patients in Oman. Keywords: Cancer; Attitudes; Patients; Surveys and Questionnaires; Oman.

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DYSLIPIDEMIA IN THYROID DISORDERS

International Journal of Medical and Biomedical Studies ◽

10.32553/ijmbs.v4i7.1308 ◽

2020 ◽

Vol 4 (7) ◽

Author(s):

Kashish Narula ◽

Narendra Kumar Dara ◽

Shyam Lal Meena

Keyword(s):

Lipid Metabolism ◽

Thyroid Dysfunction ◽

Cross Sectional Study ◽

Control Group ◽

Thyroid Disorders ◽

Cross Sectional ◽

Carbohydrate And Lipid Metabolism ◽

History Of ◽

Thyroid Profile ◽

Basal Energy Expenditure

Background: Thyroid hormones influence nearly all major metabolic pathways. Their most obvious and well-known action is the increase in basal energy expenditure obtained by acting on protein, carbohydrate and lipid metabolism. The lipid metabolism is more influenced by the thyroid hormone. Methods: A cross-sectional study was conducted on 100 patients with suspicion of thyroid disorders were taken as cases. One hundred patients with normal thyroid profile and no history of other chronic diseases were taken as control group. Results: The serum TC, TG and LDL levels in hypothyroid individuals (both overt and subclinical) were significantly higher than euthyroid subjects but the levels were comparable between hyperthyroid and euthyroid group. Conclusion: Dyslipidemias are associated with thyroid disorders, so biochemical screening for thyroid dysfunction in all dyslipidemic patients. Therefore, patients presenting with dyslipidemia are recommended for investigation to explore thyroid dysfunction. Keywords: Thyroid profile, Total cholesterol, Triglycerides and LDL

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Prevalence of Thyroid Diseases in an Occupationally Radiation Exposed Group: A Cross-Sectional Study in a University Hospital of Southern Italy

Endocrine Metabolic & Immune Disorders - Drug Targets ◽

10.2174/1871530318666181102114627 ◽

2019 ◽

Vol 19 (6) ◽

pp. 803-808 ◽

Cited By ~ 1

Author(s):

Luigi Vimercati ◽

Luigi De Maria ◽

Francesca Mansi ◽

Antonio Caputi ◽

Giovanni M. Ferri ◽

...

Keyword(s):

Ionizing Radiation ◽

Healthcare Workers ◽

Southern Italy ◽

Cross Sectional Study ◽

Thyroid Diseases ◽

University Hospital ◽

Control Group ◽

Sectional Study ◽

Cross Sectional ◽

Exposed Workers

Background: Thyroid diseases occur more frequently in people exposed to ionizing radiation, but the relationship between occupational exposure to ionizing radiation and thyroid pathologies still remains unclear. Objective: To evaluate the prevalence of thyroid diseases in healthcare workers exposed to low-level ionizing radiation compared with a control group working at the University Hospital of Bari, Southern Italy, and living in the same geographical area, characterized by mild iodine deficiency. Methods: We ran a cross-sectional study to investigate whether healthcare workers exposed to ionizing radiation had a higher prevalence of thyroid diseases. Four hundred and forty-four exposed healthcare workers (241 more exposed, or “A Category”, and 203 less exposed, or “B Category”) and 614 nonexposed healthcare workers were enrolled during a routine examination at the Occupational Health Unit. They were asked to fill in an anamnestic questionnaire and undergo a physical examination, serum determination of fT3, fT4 and TSH, anti-TPO ab and anti-TG ab and ultrasound neck scan. Thyroid nodules were submitted to fine needle aspiration biopsy when indicated. Results: The prevalence of thyroid diseases was statistically higher in the exposed workers compared to controls (40% vs 29%, adPR 1.65; IC95% 1.34-2.07). In particular, the thyroid nodularity prevalence in the exposed group was approximately twice as high as that in the controls (29% vs 13%; adPR 2.83; IC95% 2.12-3.8). No statistically significant association was found between exposure to ionizing radiation and other thyroid diseases. Conclusion: In our study, mild ionizing radiation-exposed healthcare workers had a statistically higher prevalence of thyroid diseases than the control group. The results are likely due to a closer and more meticulous health surveillance programme carried out in the ionising radiation-exposed workers, allowing them to identify thyroid alterations earlier than non-exposed health staff.

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Malaria among migrants in a university hospital in Colombia during 2018: A case series

Tropical Doctor ◽

10.1177/0049475520981301 ◽

2020 ◽

pp. 004947552098130

Author(s):

Fabián R Carreño-Almánzar ◽

Adán Coronado-Galán ◽

Sonia A Cala-Gómez ◽

Agustín Vega-Vera

Keyword(s):

Latin American ◽

Previous History ◽

Case Series ◽

Cross Sectional Study ◽

Imported Malaria ◽

University Hospital ◽

Sectional Study ◽

Cross Sectional ◽

History Of ◽

Clinical Profiles

Imported malaria has increased in Colombia since 2015 and has been attributed to migrants coming from Venezuela. We present a series of malaria cases, nested in a retrospective cross-sectional study between 2017 and 2018, aimed at calculating the prevalence of medical diseases among immigrants in a University Hospital in Colombia. Among 154 immigrants admitted for medical causes between 2017 and 2018, 8 were diagnosed with malaria, all due to Plasmodium vivax. Of these, seven had uncomplicated malaria, five had a previous history of malaria, one was critically ill, but none died. We highlight that, similar to other case series of imported malaria, Latin American migrants were young, with similar clinical profiles, having a low proportion of severe cases, and P. vivax was the most frequent cause.

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Is suicidal ideation associated with allergic asthma and allergic rhinitis?

Jornal Brasileiro de Pneumologia ◽

10.1590/s1806-37562017000000129 ◽

2018 ◽

Vol 44 (1) ◽

pp. 31-35 ◽

Cited By ~ 2

Author(s):

Martín Bedolla-Barajas ◽

Norma Angélica Pulido-Guillén ◽

Bolívar Vivar-Aburto ◽

Jaime Morales-Romero ◽

José Raúl Ortiz-Peregrina ◽

...

Keyword(s):

Allergic Rhinitis ◽

Suicidal Ideation ◽

Allergic Asthma ◽

Allergic Diseases ◽

Cross Sectional Study ◽

University Hospital ◽

Control Group ◽

Healthy Controls ◽

Cross Sectional ◽

And Control

ABSTRACT Objective: To investigate whether there is an association between suicidal ideation (SI) and allergic diseases in adults. Methods: This was a comparative cross-sectional study involving individuals ranging from 20 to 50 years of age recruited from a university hospital in the city of Guadalajara, Mexico. We included patients with a confirmed diagnosis of allergic asthma, those with a confirmed diagnosis of allergic rhinitis, and healthy controls. All subjects completed the Beck Depression Inventory-II (BDI-II), which includes an item that evaluates the presence of suicidal thoughts or desires within the last two weeks, in order to identify SI. Results: The sample comprised 115 patients with allergic asthma, 111 patients with allergic rhinitis, and 96 healthy controls. The number of individuals identified with SI in the three groups were, respectively, 17 (14.8%), 13 (11.7%), and 8 (8.3%). Regarding the presence of SI, no statistically significant association was found in the allergic asthma group (OR = 1.98; 95% CI: 0.78-4.64; p = 0.154) or in the allergic rhinitis group (OR = 1.46; 95% CI: 0.58-3.68; p = 0.424) when they were compared with the control group. However, the presence of depression was associated with SI in the three groups: allergic asthma (OR = 12.36; 95% CI: 2.67-57.15; p = 0.001); allergic rhinitis (OR = 6.20; 95% CI: 1.66-23.14; p = 0.006); and control (OR = 21.0; 95% CI: 3.75-117.36; p < 0,001). Conclusions: In comparison with the control group, no association was found between SI and the groups with allergic diseases. In contrast, there was association between SI and depression in the three groups.

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Quantitative Assessment Of The Variations In Thyroid Dimensions In Relation To Increase In Serum TSH In Euthyroids

Journal of Bahria University Medical and Dental College ◽

10.51985/jbumdc2018041 ◽

2018 ◽

Vol 08 (02) ◽

pp. 72-76

Author(s):

Mahrukh Kamran ◽

Sahar Mubeen ◽

Iffat Raza ◽

Sanobar Bughio ◽

Hira Waseem ◽

...

Keyword(s):

Total Variation ◽

Cross Sectional Study ◽

Thyroid Stimulating Hormone ◽

Left Lobe ◽

University Hospital ◽

P Value ◽

Cross Sectional ◽

Right Lobe ◽

The Right ◽

Serum Tsh

Objectives: To determine the effect of serum TSH on thyroid dimensions of each lobe and to measure the amount of effect of per unit increase in serum TSH on thyroid dimensions of each lobe in euthyroids. Study Design: It was a cross-sectional study. Setting: The study was conducted at Ziauddin University Hospital, Clifton, Karachi. Methodology: Healthy participants aged 21 years and above were included through convenient sampling. Serum Thyroid stimulating hormone was evaluated and ultrasound of thyroid gland TG of 192 euthyroid participants was performed. Spearman correlation and regression analysis was applied to evaluate the relationship between TSH and TG dimensions Results: Relationship of increase in serum TSH with decrease in light lobe AP dimension was most significant. (r= -0.142 P-Value=0.001) and CC dimension least significant (r= -0.0098 P-Value=0.001). Where as in the left lobe AP dimension decreases significantly with increase serum TSH (r= -0.147 P-value=0.001). 11.7% of total variation in AP dimension, 3.5% of total variation in ML dimension and 6.5% of total variation in CC dimension in right lobe thyroid are because of serum TSH. While 9.5% of the total variation in AP dimension in left lobe is also due to serum TSH. Conclusion: Negative and significant correlation between serum TSH and thyroid dimensions was observed. Serum TSH inversely and significantly affects all the dimensions of the right lobe and only one dimension in the left lobe

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Diagnostic, therapeutic and prognostic aspects of uterine synechiae managed by hysteroscopy in the gyanecological endoscopic surgery and human reproductive teaching hospital

International Journal of Reproduction Contraception Obstetrics and Gynecology ◽

10.18203/2320-1770.ijrcog20175833 ◽

2017 ◽

Vol 7 (1) ◽

pp. 56

Author(s):

Etienne Belinga ◽

Isidore Tompeen ◽

Claude Cyrille Noa Ndoua ◽

Junie Metogo Ntsama ◽

Sandrine Mendibi ◽

...

Keyword(s):

Past History ◽

Cross Sectional Study ◽

P Value ◽

Chi Square ◽

Cross Sectional ◽

Qualitative Variables ◽

Preoperative Diagnostic ◽

Chi Square Test ◽

Human Reproductive ◽

History Of

Background: Uterine synechiae refers to a total or partial union of the inner walls of the uterus resulting from endometrial trauma. It is a cause of reproductive failure. Until now, synechia was not optimally treated and has remained understudied in Cameroon. Objective of present study was to Evaluate the diagnostic, therapeutic and prognostic aspects of uterine synechiae treated by hysteroscopy.Methods: We conducted a descriptive cross-sectional study with an analytical component from January 1st 2015 to July 31st 2017 at Yaounde. All patients diagnosed with uterine synechiae and treated with hysteroscopy were our sample. Sampling was consecutive. The chi-square test was used for the comparison of qualitative variables and Fisher's test for ANOVA variance analysis. The comparison of the averages was made by the Student's test. P-value less than 0.05 was considered as statistically significant.Results: Hysteroscopies were indicated for uterine synechiae in 14.50%. Nulliparous were 56.67%. A history of curettage/aspiration was present in 66.66%. All of the patients had a form of infertility and 83.33% had menstrual disorders. Hysterosalpingography showed a better sensitivity (88%). After hysteroscopic treatment, 63.30% had a complete anatomical restitution. There is a significant correlation between the stage of severity of synechia and anatomical restitution (p=0.008; Spearman correlation coefficient=-0.477).Conclusions: Uterine synechiae represent one-sixth of all indications for hysteroscopy and present clinically as menstrual disorder associated with infertility. A past history of uterine curettage is common. Hysterosalpingography has a better preoperative diagnostic sensitivity. Hysteroscopy allows optimal treatment.

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Depression, anxiety levels and sleep quality indexes among the spouses of people with epilepsy

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x-anp-2020-0207 ◽

2021 ◽

Author(s):

Halil ONDER ◽

Ersin Kasim ULUSOY ◽

Caner BAYDAR ◽

Mustafa KIRAZ ◽

Muhammet Okay ORUN ◽

...

Keyword(s):

Sleep Quality ◽

Sleep Disturbances ◽

Demographic Data ◽

Cross Sectional Study ◽

Control Group ◽

Cross Sectional ◽

History Of ◽

Group 3 ◽

Group 2 ◽

Psychiatric Problems

ABSTRACT Background: Psychiatric problems and sleep disturbances are comorbidities that are frequently encountered among people with epilepsy. However, their presence among the spouses of peoples with epilepsy remains to be elucidated. Objective: The objective of this study was to evaluate the spouses of people with epilepsy (PWE), with and without a history of seizures during sleep, in terms of depression, anxiety and sleep quality. Methods: This prospective, cross-sectional study was conducted in three groups of 18 to 65-year-olds. Group 1 consisted of healthy spouses of 127 healthy volunteers without any known neurological disease; group 2 comprised spouses of 63 PWE who had no history of seizure during sleep; and group 3 consisted of spouses of 63 PWE who had a history of at least one seizure during sleep in the course of the previous year. Questionnaires seeking demographic data and the Pittsburgh Sleep Quality Index (PSQI), Beck Depression Inventory and Beck Anxiety Inventory were applied to all participants. Results: The depression scores of the group of spouses of PWE were higher than those of the control group and were higher in group 3 than in group 2 (p = 0.017). The anxiety scores of the group of spouses of PWE were significantly higher than those of the control group, but no difference in anxiety scores was found between group 2 and group 3 (p = 0.170). The mean PSQI score of group 3 was higher than that of group 2 (p = 0.029). However, regression analyses did not show any difference between these groups. Conclusion: We found that the PSQI scores, which reflected sleep quality, were higher among the spouses of PWE who had seizures during sleep and who had more severe epilepsy.

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