scholarly journals Maternal Factors Associated with Sepsis among Neonates Admitted in Kenyatta National Hospital Pediatric Wards

2020 ◽  
Vol 2 (1) ◽  
Author(s):  
Florence Muthwii ◽  
Margaret Chege ◽  
Margret Muiva ◽  
Michael Habtu
Keyword(s):  
Maternal Factors ◽  
National Hospital ◽  
Factors Associated ◽  
Kenyatta National Hospital ◽  
Hospital Pediatric

scholarly journals Prevalence, antimicrobial susceptibility patterns, serotypes and risk factors for group B streptococcus rectovaginal isolates among pregnant women at Kenyatta National Hospital, Kenya; A cross-sectional study

2019 ◽  
Author(s):  
Jisuvei Clayton Salano ◽  
Osoti Alfred ◽  
Maina Anne Njeri
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Group B Streptococcus ◽  
Penicillin G ◽  
National Hospital ◽  
Factors Associated ◽  
Kenyatta National Hospital ◽  
Group B ◽  
Susceptibility Patterns

Abstract Background: Estimates of group B streptococcus (GBS) disease burden, antimicrobial susceptibility, and serotypes in pregnant women are limited for many resource-limited countries including Kenya. These data are required to inform recommendations for prophylaxis and treatment of infections due to GBS. Methods: We evaluated the prevalence, antimicrobial susceptibility patterns, serotypes, and risk factors associated with rectovaginal GBS colonization among pregnant women receiving antenatal care at Kenyatta National Hospital (KNH) between August and November 2017. Consenting pregnant women between 12 and 40 weeks of gestation were enrolled. Interview-administered questionnaires were used to assess risk factors associated with GBS colonization. An anorectal swab and a lower vaginal swab were collected and cultured on Granada agar for GBS isolation. Positive colonies were tested for antimicrobial susceptibility to penicillin G, ampicillin, vancomycin, and clindamycin using the disk diffusion method. Serotyping was performed by latex agglutination. Logistic regression was used to identify factors associated with GBS colonization. Results: A total of 292 women were enrolled. Median age was 30 years (Interquatile range {IQR} 26-35) with a median gestational age of 35 weeks (IQR 30-37). Overall GBS was identified in 60/292 (20.5%) of participants. Among the positive isolates, resistance was detected for penicillin G in 42/60 (72.4%) isolates, ampicillin in 32/60 (55.2%) isolates, clindamycin in 14/60 (30.4%) isolates, and vancomycin in 14 (24.1%) isolates. All ten GBS serotypes were isolated, and 37/53 (69.8%) of GBS positive participants were colonized by more than one serotype. None of the risk factors was associated with GBS colonization.Conclusion: The prevalence of GBS colonization was high among mothers attending antenatal clinic at KNH. In addition, a high proportion of GBS isolates were resistant to commonly prescribed intrapartum antibiotics. Hence, other measures like GBS vaccination is a potentially useful approaches to GBS prevention and control in this population. Screening of pregnant mothers for GBS colonization should be introduced and antimicrobial susceptibility test performed on GBS positive samples to guide antibiotic prophylaxis.

scholarly journals Perceived Demographic and Socio-Economic Factors Contributing to Poor Outcome of Neonatal Sepsis at Paediatric Unit Kenyatta National Hospital

2021 ◽  
Vol 4 (1) ◽  
pp. 16-23
Author(s):  
Kimaiyo Jepkosgei ◽  
Abednego Ongeso ◽  
Blasio Omuga
Keyword(s):  
Socioeconomic Status ◽  
Neonatal Sepsis ◽  
Community Empowerment ◽  
World Health ◽  
National Hospital ◽  
Factors Associated ◽  
Kenyatta National Hospital ◽  
Paediatric Unit ◽  
Study Results ◽  
Poor Outcomes

Introduction: Globally sepsis is still a known case of high mortality and mobility rates among neonates. This is despite having been advances in healthcare quality. The World Health Organization estimates that more than 40% of deaths occurring among infants aged below five years happen during the neonatal phase and they result in 3.1 infant deaths annually. Objective: This study sought to establish the perceived demographic and socioeconomic status of poor outcomes of neonatal sepsis at Kenyatta national hospital paediatric unit. Methodology: This was a hospital-based descriptive cross-sectional study conducted in the Paediatric Unit of Kenyatta National Hospital. A total of 175 mothers of neonates with neonatal sepsis admitted in KNH selected using consecutive sampling methods were recruited into the study. A validated researcher-administered semi-structured questionnaire was used to collect the data. Descriptive statistics involved the calculation of measures of central tendencies like means, modes and medians between variables. Association between the study variables was estimated using both chi-square and odds ratio statistics at a 95% confidence interval. The study results were presented in tables, graphs and charts, as appropriate. Results:  Maternal demographic factors associated with poor outcomes of neonatal sepsis included - younger or advanced maternal age (X2 = 4.735, df = 2, p = 0.031); low education level (X2 = 6.362, df = 1, p = 0.012) and short birth intervals of < 2 years (X2 = 5.108, df = 2, p = 0.023). Maternal socioeconomic factors associated with poor outcomes of neonatal sepsis included - low household income level (X2 = 6.163, df = 1, p = 0.014); large family sizes of ≥5 members (X2 = 4.844, df = 1, p = 0.028) and lack of a health insurance cover (X2 = 5.382, df = 1, p = 0.019). Conclusion: Various maternal demographics, maternal socio-economic were significant perceived determinants of poor outcomes of neonatal sepsis in Kenyatta National Hospital’s Paediatric Unit.  Recommendations: The national government with the help of county governments and development partners should invest in community empowerment programs that aim to improve the socioeconomic status of caregivers and their households. In addition, further investments in the health care system are needed to make it more affordable to all and particularly to the low-income group.

scholarly journals Prevalence, antimicrobial susceptibility patterns, serotypes and risk factors for group B streptococcus rectovaginal isolates among pregnant women at Kenyatta National Hospital, Kenya; A cross-sectional study

2020 ◽  
Author(s):  
Jisuvei Clayton Salano ◽  
Osoti Alfred ◽  
Maina Anne Njeri
Keyword(s):  
Risk Factors ◽  
Pregnant Women ◽  
Antimicrobial Susceptibility ◽  
Group B Streptococcus ◽  
Penicillin G ◽  
National Hospital ◽  
Factors Associated ◽  
Kenyatta National Hospital ◽  
Group B ◽  
Susceptibility Patterns

Abstract Background Estimates of group B streptococcus ( GBS) disease burden, antimicrobial susceptibility, and serotypes in pregnant women are limited for many resource-limited countries including Kenya. These data are required to inform recommendations for prophylaxis and treatment of infections due to GBS. Methods We evaluated the prevalence, antimicrobial susceptibility patterns, serotypes, and risk factors associated with rectovaginal GBS colonization among pregnant women receiving antenatal care at Kenyatta National Hospital (KNH) between August and November 2017. Consenting pregnant women between 12 and 40 weeks of gestation were enrolled. Interview-administered questionnaires were used to assess risk factors associated with GBS colonization. An anorectal swab and a lower vaginal swab were collected and cultured on Granada agar for GBS isolation. Positive colonies were tested for antimicrobial susceptibility to penicillin G, ampicillin, vancomycin, and clindamycin using the disk diffusion method. Serotyping was performed by latex agglutination. Logistic regression was used to identify factors associated with GBS colonization. Results A total of 292 women were enrolled. Median age was 30 years (Interquatile range {IQR} 26-35) with a median gestational age of 35 weeks (IQR 30-37). Overall GBS was identified in 60/292 (20.5%) of participants. Among the positive isolates, resistance was detected for penicillin G in 42/58 (72.4%) isolates, ampicillin in 32/58 (55.2%) isolates, clindamycin in 14/46 (30.4%) isolates, and vancomycin in 14/58 (24.1%) isolates. All ten GBS serotypes were isolated, and 37/53 (69.8%) of GBS positive participants were colonized by more than one serotype. None of the risk factors was associated with GBS colonization. Conclusion The prevalence of GBS colonization was high among mothers attending antenatal clinic at KNH. In addition, a high proportion of GBS isolates were resistant to commonly prescribed intrapartum antibiotics. Hence, other measures like GBS vaccination is a potentially useful approaches to GBS prevention and control in this population. Screening of pregnant mothers for GBS colonization should be introduced and antimicrobial susceptibility test performed on GBS positive samples to guide antibiotic prophylaxis.

scholarly journals Risk Factors Associated with Severity of Nongenetic Intellectual Disability (Mental Retardation) among Children Aged 2–18 Years Attending Kenyatta National Hospital

2018 ◽  
Vol 2018 ◽  
pp. 1-11 ◽  
Author(s):  
Mathieu Nemerimana ◽  
Margaret Njambi Chege ◽  
Eunice Ajode Odhiambo
Keyword(s):  
Risk Factors ◽  
Intellectual Disability ◽  
Neonatal Intensive Care ◽  
Cross Sectional Study ◽  
Perinatal Complications ◽  
National Hospital ◽  
Cross Sectional ◽  
Factors Associated ◽  
Kenyatta National Hospital ◽  
Increased Risk

Background. Many of the nongenetic causal risk factors of intellectual disability (ID) can be prevented if they are identified early. There is paucity on information regarding potential risk factors associated with this condition in Kenya. This study aimed to establish risk factors associated with severity of nongenetic intellectual disability (ID) among children presenting with this condition at Kenyatta National Hospital (KNH). Methods. A hospital-based cross-sectional study was conducted over the period between March and June 2017 in pediatric and child/youth mental health departments of Kenyatta National Hospital (KNH), Kenya. It included children aged 2–18 years diagnosed with ID without underlying known genetic cause. Results. Of 97 patients with nongenetic ID, 24% had mild ID, 40% moderate, 23% severe-profound, and 10% unspecified ID. The mean age of children was 5.6 (±3.6) years. Male children were predominant (62%). Three independent factors including “labor complications” [AOR = 9.45, 95% CI = 1.23–113.29, P=0.036], “admission to neonatal intensive care unit” [AOR = 8.09, 95% CI = 2.11–31.07, P=0.002], and “cerebral palsy” [AOR = 21.18, CI = 4.18–107.40, P≤0.001] were significantly associated with increased risk of severe/profound nongenetic ID. Conclusion. The present study findings suggest that perinatal complications as well as postnatal insults are associated with increased risk of developing severe-profound intellectual disability, implying that this occurrence may be reduced with appropriate antenatal, perinatal, and neonatal healthcare interventions.

scholarly journals DEMOGRAPHIC FACTORS ASSOCIATED WITH INCREASING INCIDENCES OF BURNS AMONG ADULT PATIENTS ADMITTED IN THE KENYATTA NATIONAL HOSPITAL BURNS UNIT

2016 ◽  
Vol 1 (1) ◽  
pp. 68-78
Author(s):  
Nelly C Amakobe ◽  
Dr. Makori Moronge
Keyword(s):  
Demographic Factors ◽  
Descriptive Statistics ◽  
Adult Patients ◽  
Primary Data ◽  
Unique Contribution ◽  
National Hospital ◽  
Factors Associated ◽  
Kenyatta National Hospital ◽  
Number Of Patients ◽  
Burns Unit

Purpose: The purpose of the study was to establish the demographic factors associated with increasing incidences of burns among adult patients admitted in the Kenyatta National Hospital Burns UnitMethodology: The population of this research consisted of all patients in the burns unit at Kenyatta hospital. The study used primary data in particular used questionnaires. The questionnaire consisted of structured closed ended statements. Data was analyzed using Statistical Package for Social Sciences (SPSS) mainly by use of descriptive statistics. Descriptive statistics included mode, mean, median, standard deviation. Data was presented by use of graphs, pie charts and tables.Results: The study findings indicated that there has been an increase in number of patients with burns which is associated with various demographics factors causing the increased incidences among the patients. Unique contribution to theory, practice and policy: From the study findings the researcher  recommend that it’s important to educate the  citizens in order to make them more aware of the dangers associated with various factors such as illegal electricity connection and lack of access roads.  In doing this more cases of fire would be reduced and reduce loss of lives and property in more fire prone areas. The study also recommends that the Government through the Ministry of Public Health and Sanitation should impart knowledge related to the burns especially on how people can take preventive measures and emergency measures against fire outbreak.   

scholarly journals Prevalence and factors associated with preterm birth at kenyatta national hospital

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Peter Wagura ◽  
Aggrey Wasunna ◽  
Ahmed Laving ◽  
Dalton Wamalwa ◽  
Paul Ng’ang’a
Keyword(s):  
Preterm Birth ◽  
National Hospital ◽  
Factors Associated ◽  
Kenyatta National Hospital
Sign in / Sign up

Export Citation Format

Share Document