Tick Borne Encephalitis

2021 ◽  
Author(s):  
Gerhard Dobler

Tick-borne encephalitis (TBE) is the medically most common tick-borne viral disease in Europe and Asia. The TBE virus (TBEV) is a member of the family Flaviviridae. Transmission mainly to humans occurs by ticks of the Family Ixodidae, mainly the castor bean tick (Ixodes ricinus) in Europe and the taiga tick (Ixodes persulcatus) in Asia. Rarely TBEV is also transmitted by contaminated milk of infected ungulates (goat, sheep, cow). The clinical course of TBE is variable and may range from subclinical to fatal encephalomyelitis. Probably host and viral factors are involved in the pathogenesis of disease. So far, no specific treatment of the disease is available. The only effective prevention of TBE is vaccination. A number of different vaccines are available worldwide. In Europe two vaccines are licensed which contain inactivated European subtype TBEV. Probably the European vaccines protect also against infections with other subtypes of TBEV.

2018 ◽  
Vol 39 (4) ◽  
pp. 191 ◽  
Author(s):  
Gerhard Dobler

Tick-borne encephalitis (TBE) is the most important tick-transmitted human viral disease in Europe and Asia with up to 10000 human cases annually. The etiologic agents of TBE are the three subtypes of tick-borne encephalitis virus (TBEV), a member of the genus Flavivirus in the family Flaviviridae. The Far-Eastern subtype and the Siberian subtype are both mainly transmitted by Ixodes persulcatus; the European subtype is mainly transmitted by Ixodes ricinus. Besides tick bite, TBEV can be transmitted by unpasteurised milk from goat, sheep and cattle during the viremic phase of infection by the oral route of infection (alimentary form of TBE). There is no treatment for TBE available, but there are effective and well tolerated vaccines against TBE, which are recommended for people living or travelling to endemic countries with a risk of infection.


2021 ◽  
pp. 438-443
Author(s):  
Eduard Korenberg

Abstract This expert opinion considers only the most significant aspects of the impact of climate change on ticks and tick-borne diseases in Russia. Attention is focused on the species that are most widespread in the extratropical part of the northern hemisphere: the taiga tick, Ixodes persulcatus, and the European forest tick, I. ricinus, which are hosts and vectors of tick-borne encephalitis (TBE) virus and Borrelia spirochaetes, agents of ixodid tickborne borrelioses (ITBBs), i.e. of Lyme and Lyme-like diseases.


Even though tick-borne encephalitis (TBE) has been a notifiable disease in Croatia since 2007, there are no or only limited data available on the occurring tick species in the endemic areas, on the prevalence of TBE virus (TBEV) in ticks, its distribution in Croatia, and its genetic characteristics. Reporting of human cases also is very scarce. The Central European subtype of virus (TBEV-EU) appears to be present in Croatia


Author(s):  
Wilhelm Erber ◽  
Tamara Vuković Janković

Even though tick-borne encephalitis (TBE) has been a notifiable disease in Croatia since 2007, there are no or only limited data available on the occurring tick species in the endemic areas, on the prevalence of TBE virus (TBEV) in ticks, its distribution in Croatia, and its genetic characteristics. Reporting of human cases also is very scarce. The Central European subtype of virus (TBEV-EU) appears to be present in Croatia.


Author(s):  
Wilhelm Erber ◽  
Tamara Vuković-Janković

Even though tick-borne encephalitis (TBE) has been a notifiable disease in Croatia since 2007, there are no or only limited data available on the occurring tick species in the endemic areas, on the prevalence of TBE virus (TBEV) in ticks, its distribution in Croatia, and its genetic characteristics. Reporting of human cases also is very scarce. The Central European subtype of virus (TBEV-EU) appears to be present in Croatia.


Open Physics ◽  
2020 ◽  
Vol 18 (1) ◽  
pp. 820-828
Author(s):  
Saima Akram ◽  
Aroosa Arooj ◽  
Nusrat Yasmin ◽  
Abdul Ghaffar ◽  
Dumitru Baleanu ◽  
...  

AbstractTick-borne encephalitis (TBE) is a flaviviral vector-borne disease, which is spread by a tick named Ixodes persulcatus in domestic animals as well as in humans. In this article, susceptible, exposed, infected, recovered model; with no immunity after getting recovered is taken. The only possible immunity is before getting the disease (in our model). The vaccination details are also discussed in the article. Hence, SEIS (susceptible, exposed, infected and again susceptible with zero removal from the specie compartment) is used to construct a mathematical model of TBE. TBE is acute inflammation of the brain parenchyma. After becoming viral in European states and some Asian countries, especially in China, this is an emerging viral disease in Pakistan. After constructing a model, formula for the basic reproduction number R0-like threshold has been derived by using the next-generation matrix method. The formula for R0-like threshold is used to evaluate whether the disease is going to be outbroken in the respective area from which the specific data are taken into consideration. The main motivation behind selection of this topic is to address the unawareness of this disease specifically in Pakistan and in its neighboring countries when there persists probability for the outbreak of this disease. Some equilibrium points and their local stability is also discussed. Numerical computations and graphs are also presented to validate the results.


2021 ◽  
pp. 331-340
Author(s):  
Vlasta Danielová ◽  
Milan Daniel

Abstract Tick-borne encephalitis (TBE) is a serious human disease of the central nervous system (CNS) caused by the European subtype of tick-borne encephalitis virus (TBEV) - genus Flavivirus of the family Flaviviridae - in the European area of its distribution. Its major vector is the tick, Ixodes ricinus. This expert opinion discusses the ecology of I. ricinus and the epidemiology of TBE in relation to changing climate in Central Europe.


2020 ◽  
Vol 10 (3) ◽  
pp. 533-542
Author(s):  
E. A. Siuziumova ◽  
N. V. Telnova ◽  
A. O. Shapar ◽  
B. I. Aslanov ◽  
N. A. Stoyanova ◽  
...  

Here, we provide an analysis on 1996–2016 St. Petersburg tick-borne encephalitis (TBE) epidemiological and ecological data. In particular, two main TBE transmission vectors were observed in St. Petersburg: Ixodes persulcatus Ixodes ricinus. TBE tick contamination was 0.61% as shown by ELISA and polymerase chain reaction data. It is found that number of subjects seeking for medical aid due to tick bites rises, whereas TBE incidence declines. In particular, a mean 1996–2002 vs. 2010–2016 tick-bite incidence rate increased from 141.9 up to 288.9, respectively. Despite that the Leningrad region is a major area for TBE spread, however, a risk of exposure to tick bites as well as TBE infection exists even in the city of St. Petersburg. In connection with this, around 1,000 subjects undergo tick bites within the city limits. Moreover, whereas a 1996–2002 mean TBE incidence rate was 1.66, it decreased in 2010–2016 down to 1.17. A peak TBE incidence was documented in St. Petersburg Kurortny, Pushkinsky and Primorsky districts. In addition, males vs. females suffered from TBE at higher frequency in Russian Federation, with its peak incidence rate being reported in children under 14 that differs St. Petersburg from the most of other regions in the Russian Federation. A seasonal distribution of TBE cases in St. Petersburg does not differ from that one for the remainder of Russian regions, which displays a spring-summer seasonality lasting from April to September. Of note, 1996–2016 St. Petersburg TBE mortality was 1.37%. A coverage of TBE vaccinated population tends to rise but still remains at low level (0.25–0.58%). Lack of reported TBE cases in occupationally threatened human cohorts evidences about efficient preventive measures. Detection of TBE virus-specific serum antibodies in 5.0% apparently healthy and unvaccinated residents in St. Petersburg significantly complements the official TBE recording data and provides a more accurate understanding of its actual spread.


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