scholarly journals Mandibular reconstruction with microvascularized graft after ameloblastoma resection: case series

2021 ◽  
Vol 10 (15) ◽  
pp. e217101522594
Author(s):  
Kaiane Tavares Pontes ◽  
Yasmin Lima Nascimento ◽  
Maelly Vicente Lôbo ◽  
Taysnara Ismaeley de Andrade ◽  
Jonathan Augusto Vidal de Oliveira ◽  
...  

Ameloblastoma is a locally aggressive and highly infiltrative tumor with a high recurrence rate. Its multicystic form the recommended treatment is resection with a safety margin, which results in significant facial defects with esthetic and functionals repercussions. Microvascular surgery revolutionized the reconstruction of significant defects because these grafting techniques allow a more satisfactory aesthetic and functional restoration. This study aimed to report a series of cases of reconstructions of mandibular defects using microvascularized fibular graft after ameloblastoma resection. Six patients were included in this study, and we collected data related to the surgical procedure, diagnosis, complications and follow-up. The patients were characterized as four women and two men, with a mean age of 23.8 years, with a diagnosis of mandibular ameloblastoma located mainly in the body, angle and mandibular ramus. These patients underwent lesion resection, resulting in defects larger than 5 cm, which justified using a microvascularized fibular graft for its reconstruction. The patients evolved well, with good results and without recurrences or complications in a postoperative follow-up of 2 to 5 years. Ameloblastoma is a lesion that reaches large dimensions and causes excellent cosmetic and functional damage. The microvascularized graft is an alternative in reconstructing significant defects and allows satisfactory morphofunctional reestablishment with minimal complications.

2019 ◽  
Vol 8 (1) ◽  
pp. 46
Author(s):  
Tomasz Chorągiewicz ◽  
Katarzyna Nowomiejska ◽  
Dariusz Haszcz ◽  
Dominika Nowakowska ◽  
Teresio Avitabile ◽  
...  

Introduction: To assess long-term outcomes of implantation of black diaphragm intraocular lens (BD IOL) in post-traumatic aniridia and aphakia due to eye rupture. Methods: This is a retrospective consecutive case series of 14 eyes with post-traumatic complete aniridia and aphakia treated with scleral fixation BD IOL. Measurements included ophthalmological comorbidities, best corrected visual acuity (BCVA), complications, and postoperative interventions. The average postoperative follow-up period was 36 months. Results: BCVA improved in 6 cases, was stable in 6 cases and worsened in 2 cases. The lens was well centered in 13 cases. Glaucoma was diagnosed in six cases developed, and three of them required Ahmed valve implantation. One lens developed opacity. The cornea was decompensated in 6 cases, while two of them required penetrating keratoplasty. Conclusion: Implantation of BD IOL in eyes with severely traumatized eyes enables reconstruction of the anterior segment and some functional restoration, although many complications may arise during the longitudinal follow-up.


2021 ◽  
Vol 15 (Supplement_1) ◽  
pp. S215-S216
Author(s):  
S Festa ◽  
G Zerboni ◽  
L Derikx ◽  
D G Ribaldone ◽  
G Dragoni ◽  
...  

Abstract Background Neuroendocrine Neoplasms (NENs) are a heterogeneous group of tumours deriving from the diffuse endocrine system. NENs may occur almost everywhere in the body but are most common in the gastrointestinal tract, the pancreas, and the lungs, with gastroenteropancreatic (GEP) tumours representing 70% of all NENs. GEP-NENs have rarely been reported in association with inflammatory bowel diseases (IBDs) but no definitive relationship between these tumours and IBD has been established Methods This was an ECCO COllaborative Network For Exceptionally Rare case reports project (ECCO-CONFER). We included cases of GEP-NENs diagnosed in patients with IBD that met the diagnostic criteria for NEN according to the European Neuroendocrine Tumour Society. Data were retrospectively collected in a standardized case report form and analysed for event association with patient’s and IBD-related factors Results GEP-NEN was diagnosed in 100 patients with IBD [61% female, 55% Crohn’s disease, median age 48 years (IQR 37–59)]. Overall the most common location was the appendix (39/100) followed by the colon (22/100). Complete IBD-related data was available for 50 individuals with a median follow-up of 30.5 months (IQR 11.2–70) following NEN diagnosis. At the last follow-up data, 47/50 patients were alive. Three deaths occurred, of which 2 were related to NEN. Median duration of IBD at NEN diagnosis was 84 months (IQR 10–151), and in 18% of cases NEN and IBD were diagnosed concomitantly. 20/50 of NENs were at stage I (T1N0M0) and 28/50 graded G1 (ki 67 ≤2 %) at diagnosis. Incidental diagnosis of NEN either during follow-up or during surgery as well as receiving diagnosis of NEN concomitantly with IBD was significantly associated with an earlier NEN stage (p< 0.01 and p<0.02, respectively). Exposure to immunomodulatory and/or biologic therapy was not associated with advanced NEN stage or grade. Interestingly, primary GEP-NEN sites significantly correlated to the segment affected by IBD (62% vs 38% p = 0.02) Conclusion In the largest case series to date, prognosis of patients with concomitant GEP-NEN and IBD seems favorable. Incidental NEN diagnosis correlates with an earlier NEN stage and IBD-related therapies are independent of NEN stage and grade. The association of GEP-NEN location and the segment affected by IBD may suggest a possible role of inflammation in NEN tumorigenesis


2017 ◽  
Vol 06 (03) ◽  
pp. 238-243 ◽  
Author(s):  
Ayat Oufkir ◽  
Cyril Lazerges ◽  
Bertrand Coulet ◽  
Michel Chammas

Background Giant cell tumor (GCT) of bone is rare in the carpus, and only 11 cases have been reported in the capitate bone. The problem with this location is the high recurrence rate due to easy extension to the adjacent joint spaces and bones. We describe a case of GCT on the capitate bone and the treatment in comparison with the previously reported cases. Case Description The case report concerns a 48-year-old woman with a GCT of the capitate diagnosed on curettage. The treatment consisted of large resection with the lunatum and third metacarpal arthrodesis, with a successful union at 2 years follow-up, no recurrence, and an improved function of the wrist. Literature Review When treated by curettage (alone or with adjuvant procedures), the GCT of the capitate recurred in four out of five cases. All tumors treated with large resection did not recur. Clinical Relevance Recommended treatment of GCT of the capitate is resection with carpometacarpal arthrodesis.


2016 ◽  
Vol 10 (1) ◽  
pp. 117-123 ◽  
Author(s):  
Ahmed H. Kamil ◽  
Bassel Tarakji

Objective: Is to highlight the characteristics and management of odontogenic keratocyst in children only Material and Method: Computerized search in pubmed between (2005-2015) using specific words such as odontogenic keratocyst in children, odontogenic keratocyst association with Gorlin-Goltz syndrome with abstract written in English only. Result: During computerized literature search 77 articles in the years (2005-2015) were found. All these publications were miscellaneous studies including case series and case reports. Only 35 papers were selected which conform to our criteria. Most of the papers indicate that the histological type of keratocyst prevalent in children was parakeratinized variant, and most of the cases occurred in maxilla rather than mandible. Conclusion: We recommend that the surgeons who treat keratocysts in children take into consideration the late presentation in addition to the destructive nature and high recurrence rate. General practitioners face difficulty in early detection and referral of children with keratocysts or Gorlin syndrome. Treatment by multidiscplinary team is important if associated with Gorlin's syndrome Postoperative follow up is advised every 6 months.


2019 ◽  
Vol 13 (2) ◽  
pp. 104-111
Author(s):  
Vinícius Felipe Pereira ◽  
Vitor Yoshiura Masuda ◽  
Hilário Boatto ◽  
Hélio Da Cunha Pereira Junior ◽  
José Carlos Figueiredo Fernandes Junior ◽  
...  

Objective: To present the radiographic and functional outcomes of a series of 11 cases of ankle arthrodesis performed with a circular external fixator using the Ilizarov method and a transfusion approach, conducted between January 2017 and June 2018. Methods: The patients were evaluated according to American Orthopedic Foot and Ankle Society (AOFAS) and visual analogue scale (VAS) scores. Ankle radiographs were evaluated on anteroposterior and profile views. All patients underwent a similar procedure regarding the surgical approach and assembly of the Ilizarov apparatus. Results: Eleven patients, with a mean age of 44.81 years (28-70 years), underwent surgery. The average follow-up time was 50.81 weeks (13-90 weeks). The main indication for surgery was post-traumatic secondary arthritis. The mean functional AOFAS score was 55.72 (45-64) points. An evaluation of the soft tissues revealed surgical wound healing of the transfibular approach in 9 patients (81%). All cases showed signs of superficial pin- or wire-tract infection. Union was reported in 10 patients (90.9%), and the radiographic varus deformities found in 2 patients did not exceed 7º. No additional surgical procedure was required during follow-up. Conclusion: Ankle arthrodesis performed by a transfibular approach and fixation performed by the Ilizarov method were efficient, promoted the functional restoration of the patient, considering the complexity of the cases, and resulted in a high union rate. Level of Evidence IV; Therapeutic Studies; Case Series.


2021 ◽  
Vol 20 (1) ◽  
Author(s):  
Jonathan Vogel ◽  
Shaun de Villiers ◽  
Walid Mug la ◽  
Jeannie McCaul ◽  
Keith Hosking ◽  
...  

ABSTRACT BACKGROUND: Radiation-induced pathological fractures of the proximal femur are difficult to treat due to frequent non-union and hardware failure using standard fracture fixation techniques. This case series investigates endoprosthetic replacement as a treatment option METHODS: A retrospective folder review from a private hospital in Cape Town, of patients who had sustained a radiation-induced pathological fracture, was reviewed using descriptive statistics. RESULTS: Six patients met the inclusion criteria. One patient was excluded as the minimum follow-up time of six months was not met. Of the Ave patients that were analysed, all Ave sustained transverse, subtrochanteric femur fractures. Prior to definitive treatment with a proximal femoral replacement, three patients were treated with standard trauma instrumentation prior to referral to the unit, and one patient was treated with a vascularised fibular graft as their initial treatment while at the unit. One patient was treated with an endoprosthetic replacement as their first procedure at the unit. Among the three patients treated with standard trauma fixation and the one patient treated with a vascularised fibular graft, there was a 100% failure rate. One standard trauma instrumentation patient had an ablation due to free musculocutaneous flap failure and periprosthetic infection after endoprosthetic replacement. This was the only complication of endoprosthetic replacement. At a median follow-up of 15 months (min 7, max 55) the median Musculoskeletal Tumour Society score was 74% (min 63%, max 93%. CONCLUSION: This case series seeks to highlight the high failure rates seen when treating this condition with standard trauma instrumentation or biological methods. Further research is needed, but endoprosthetic replacement may be a viable alternative solution Level of evidence: Level 4. Keywords: radiation-induced fracture, pathological fracture, endoprosthetic replacement


2020 ◽  
Vol 9 (2) ◽  
pp. 1-5
Author(s):  
Ravi Singh Dogra ◽  
Arjun Singh ◽  
Vinay Bhardwaj ◽  
Poonam ◽  
Srijan Pandey ◽  
...  

Tuberculosis is a highly prevalent disease in developing countries, the majority of cases are pulmonary and rest are extra-pulmonary. Cervical LN tuberculosis is one of the most common types of extra-pulmonary tuberculosis. Isolated cervical tubercular Lymphadenitis without accompanying pulmonary tuberculosis or another form of tuberculosis in the body is rare and, when present, requires thorough clinical examination and investigation. In the investigation of such patients, FNAC plays a major role, and aspirate should be tested for AFB through ZN stain and CBNAAT (PCR). Cervical tubercular Lymphadenitis is mainly a disease of young with a female predominance. All patients of cervical tubercular Lymphadenitis must receive antitubercular therapy with strict follow up for compliance and possible side effects from treatment.


2018 ◽  
Vol 21 (02) ◽  
pp. 367-372
Author(s):  
. Yousaf Jan ◽  
Waqas , ◽  
Ihsan Ul Haq

Background: An intestinal stoma is a surgically created opening of the bowelonto the body surface. Temporary ostomies can be created from small or large bowel in a varietyof manners and serves a valuable role in persons undergoing surgery for acute infectious events,malignancy or trauma. Temporary faecal diversion is recommended with a low colorectal,coloanal or ileoanal anastomosis. Objective: To find the frequency of wound infection followingintestinal stoma closure. Materials and methods: The case series study was conducted insurgical unit Hayatabad medical complex Peshawar over 139 patients between March 2008 toAugust 2009. Closure was done on the next day of admission. Patients were advised to report toOPD if they develop wound infection in between follow up visits. Data were collected using aspecially designed proforma. Results: Out of 139 patients, 104(74.82%) were male and35(25.18%) were female. Colostomy was done in 78(56.1%) patients and ileostomy in 61(43.9%)of patients. Average age was 35.69 years ±16.5SD. There are 11(7.9%) wound infectionobserved during the hospital while at 30th day of post-op follow up decreased to just 3(2.2%).Average hospital stay was 4.96 days ± 2.06SD with a range of 3-10 days. Conclusions: Woundinfection was observed as compared to other national and international studies. Male were threetimes more than females and wound infection was seen more in males.


Author(s):  
Jae Ik Lee ◽  
Mohd Shahrul Azuan Jaffar ◽  
Han Gyeol Choi ◽  
Tae Woo Kim ◽  
Yong Seuk Lee

AbstractThe purpose of this study was to evaluate the outcomes of isolated medial patellofemoral ligament (MPFL) reconstruction, regardless of the presence of predisposing factors. A total of 21 knees that underwent isolated MPFL reconstruction from March 2014 to August 2017 were included in this retrospective series. Radiographs of the series of the knee at flexion angles of 20, 40, and 60 degrees were acquired. The patellar position was evaluated using the patellar tilt angle, sulcus angle, congruence angle (CA), and Caton-Deschamps and Blackburne-Peel ratios. To evaluate the clinical outcome, the preoperative and postoperative International Knee Documentation Committee (IKDC) and Lysholm knee scoring scales were analyzed. To evaluate the postoperative outcomes based on the predisposing factors, the results were separately analyzed for each group. Regarding radiologic outcomes, 20-degree CA was significantly reduced from 10.37 ± 5.96° preoperatively to −0.94 ± 4.11° postoperatively (p = 0.001). In addition, regardless of the predisposing factors, delta values of pre- and postoperation of 20-degree CA were not significantly different in both groups. The IKDC score improved from 53.71 (range: 18–74) preoperatively to 94.71 (range: 86–100) at the last follow-up (p = 0.004), and the Lysholm score improved from 54.28 (range: 10–81) preoperatively to 94.14 (range: 86–100) at the last follow-up (p = 0.010). Isolated MPFL reconstruction provides a safe and effective treatment for patellofemoral instability, even in the presence of mild predisposing factors, such as trochlear dysplasia, increased patella height, increased TT–TG distance, or valgus alignment. This is a Level 4, case series study.


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