scholarly journals Influence of Breathing on the Measurement of Lipids in the Myocardium by 1H MR Spectroscopy

2015 ◽  
pp. S403-S409
Author(s):  
M. DROBNY ◽  
P. SEDIVY ◽  
M. DEZORTOVA ◽  
D. WAGNEROVA ◽  
M. HAJEK
Keyword(s):  
Lipid Content ◽  
Mr Spectroscopy ◽  
Interventricular Septum ◽  
Free Breathing ◽  
Mean Value ◽  
Breath Hold ◽  
Published Data ◽  
Respiratory Navigator ◽  
1H Mr Spectroscopy ◽  
The One

The myocardium examination by MR spectroscopy is very challenging due to movements caused by the cardiac rhythm and breathing. The aim of the study was to investigate the influence of breathing on the quantitative measurement of lipid/water ratios in different groups of volunteers and different measuring protocols. We examined the lipid content of myocardium at 3T using the proton single voxel spectroscopy. Three protocols (free breathing, breath hold and the use of respiratory navigator) controlled by ECG were used for the examination of 42 adult volunteers including 14 free divers. Spectra were evaluated using jMRUI software. An average content of lipids in the healthy interventricular septum, gained by all protocols was equal to 0.6 %, which is in agreement with other published data. Based on the quality of examinations and the highest technical success, the best protocol seems to be the one containing a respiratory navigator since it is more acceptable by patients. Based on our results and the literature data we can conclude that MR spectroscopy is able to distinguish patients from controls only if their myocardial lipid content is higher than 1.6 % (mean value of lipids plus two standard deviations).

scholarly journals Comparison of single-voxel 1H-cardiovascular magnetic resonance spectroscopy techniques for in vivo measurement of myocardial creatine and triglycerides at 3T

2021 ◽  
Vol 23 (1) ◽  
Author(s):  
Joevin Sourdon ◽  
Tangi Roussel ◽  
Claire Costes ◽  
Patrick Viout ◽  
Maxime Guye ◽  
...  
Keyword(s):  
Cardiovascular Magnetic Resonance ◽  
Magnetic Resonance ◽  
Magnetic Resonance Spectroscopy ◽  
Linear Regression Analysis ◽  
Interventricular Septum ◽  
Free Breathing ◽  
Breath Hold ◽  
Resonance Spectroscopy ◽  
Single Voxel

Abstract Background Single-voxel proton cardiovascular magnetic resonance spectroscopy (1H-CMRS) benefits from 3 T to detect metabolic abnormalities with the quantification of intramyocardial fatty acids (FA) and creatine (Cr). Conventional point resolved spectroscopy (PRESS) sequence remains the preferred choice for CMRS, despite its chemical shift displacement error (CSDE) at high field (≥ 3 T). Alternative candidate sequences are the semi-adiabatic Localization by Adiabatic SElective Refocusing (sLASER) recommended for brain and musculoskeletal applications and the localized stimulated echo acquisition mode (STEAM). In this study, we aim to compare these three single-voxel 1H-CMRS techniques: PRESS, sLASER and STEAM for reproducible quantification of myocardial FA and Cr at 3 T. Sequences are compared both using breath-hold (BH) and free-breathing (FB) acquisitions. Methods CMRS accuracy and theoretical CSDE were verified on a purposely-designed fat–water phantom. FA and Cr CMRS data quality and reliability were evaluated in the interventricular septum of 10 healthy subjects, comparing repeated BH and free-breathing with retrospective gating. Results Measured FA/W ratio deviated from expected phantom ratio due to CSDE with all sequences. sLASER supplied the lowest bias (10%, vs -28% and 27% for PRESS and STEAM). In vivo, PRESS provided the highest signal-to-noise ratio (SNR) in FB scans (27.5 for Cr and 103.2 for FA). Nevertheless, a linear regression analysis between the two BH showed a better correlation between myocardial Cr content measured with sLASER compared to PRESS (r = 0.46; p = 0.03 vs. r = 0.35; p = 0.07) and similar slopes of regression lines for FA measurements (r = 0.94; p < 0.001 vs. r = 0.87; p < 0.001). STEAM was unable to perform Cr measurement and was the method with the lowest correlation (r = 0.59; p = 0.07) for FA. No difference was found between measurements done either during BH or FB for Cr, FA and triglycerides using PRESS, sLASER and STEAM. Conclusion When quantifying myocardial lipids and creatine with CMR proton spectroscopy at 3 T, PRESS provided higher SNR, while sLASER was more reproducible both with single BH and FB scans.

scholarly journals Myocardial lipid content in Fabry disease: a combined 1H-MR spectroscopy and MR imaging study at 3 Tesla

2016 ◽  
Vol 16 (1) ◽  
Author(s):  
B. Petritsch ◽  
H. Köstler ◽  
A. M. Weng ◽  
M. Horn ◽  
T. Gassenmaier ◽  
...  
Keyword(s):  
Mr Imaging ◽  
Fabry Disease ◽  
Lipid Content ◽  
Mr Spectroscopy ◽  
Imaging Study ◽  
3 Tesla ◽  
1H Mr Spectroscopy

Non-invasive Determination of Myocardial Lipid Content in Fabry Disease by 1H-MR Spectroscopy

2012 ◽  
Vol 184 (11) ◽  
pp. 1020-1025 ◽  
Author(s):  
B. Petritsch ◽  
H. Köstler ◽  
W. Machann ◽  
M. Horn ◽  
A. Weng ◽  
...  
Keyword(s):  
Fabry Disease ◽  
Lipid Content ◽  
Mr Spectroscopy ◽  
Non Invasive ◽  
1H Mr Spectroscopy

Comparison of breath-hold and free-breathing quantitative pulmonary perfusion MRI

Pneumologie ◽  
2012 ◽  
Vol 66 (06) ◽  
Author(s):  
D Maxien ◽  
M Ingrisch ◽  
F Meinel ◽  
S Thieme ◽  
MF Reiser ◽  
...  
Keyword(s):  
Free Breathing ◽  
Perfusion Mri ◽  
Breath Hold ◽  
Pulmonary Perfusion

1H-MR spectroscopy at 7.0 T and intra-individual comparison to 3.0 T and 1.5 T

2007 ◽  
Vol 179 (03) ◽  
Author(s):  
F Traeber ◽  
JR Duraj ◽  
J Gieseke ◽  
FG Hoogenraad ◽  
CK Kuhl ◽  
...  
Keyword(s):  
Mr Spectroscopy ◽  
1H Mr Spectroscopy ◽  
Individual Comparison ◽  
3.0 T

Measurement of Lipid Content in Gallbladder Bile Using in- and opposed-phase MR Images and in vivo Proton MR Spectroscopy

2002 ◽  
Vol 46 (2) ◽  
pp. 127
Author(s):  
Sun Jin Hur ◽  
Seok Hwan Shin ◽  
Geum Nan Jee ◽  
Eun Joo Yun ◽  
Soon Gu Cho ◽  
...  
Keyword(s):  
Lipid Content ◽  
Mr Spectroscopy ◽  
Gallbladder Bile ◽  
Mr Images ◽  
Proton Mr Spectroscopy

1H MR Spectroscopy in Parkinson's Disease and Progressive Supranuclear Palsy: Preliminary Study

1996 ◽  
Vol 34 (6) ◽  
pp. 711
Author(s):  
Kee Hyun Chang ◽  
Beom Seok Jeon ◽  
In Chan Song ◽  
Dong Sung Kim ◽  
Kwan Hong Min ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Progressive Supranuclear Palsy ◽  
Mr Spectroscopy ◽  
1H Mr Spectroscopy ◽  
Preliminary Study

In Vivo Single Voxel 1H MR Spectroscopy in Cerebral Glioma

1996 ◽  
Vol 35 (3) ◽  
pp. 307 ◽  
Author(s):  
In Chan Song ◽  
Kee Hyun Chang ◽  
Moon Hee Han ◽  
Hee Won Jung ◽  
Dong Sung Kim ◽  
...  
Keyword(s):  
Mr Spectroscopy ◽  
Cerebral Glioma ◽  
1H Mr Spectroscopy ◽  
Single Voxel

scholarly journals Thinner Sea Ice Contribution to the Remarkable Polynya Formation North of Greenland in August 2018

2021 ◽  
Author(s):  
Xiaoyi Shen ◽  
Chang-Qing Ke ◽  
Bin Cheng ◽  
Wentao Xia ◽  
Mengmeng Li ◽  
...  
Keyword(s):  
Sea Ice ◽  
Ice Cover ◽  
Reanalysis Data ◽  
Mean Value ◽  
Ocean Model ◽  
North Coast ◽  
Average Value ◽  
The North ◽  
Wind Sea ◽  
The One

AbstractIn August 2018, a remarkable polynya was observed off the north coast of Greenland, a perennial ice zone where thick sea ice cover persists. In order to investigate the formation process of this polynya, satellite observations, a coupled ice-ocean model, ocean profiling data, and atmosphere reanalysis data were applied. We found that the thinnest sea ice cover in August since 1978 (mean value of 1.1 m, compared to the average value of 2.8 m during 1978–2017) and the modest southerly wind caused by a positive North Atlantic Oscillation (mean value of 0.82, compared to the climatological value of −0.02) were responsible for the formation and maintenance of this polynya. The opening mechanism of this polynya differs from the one formed in February 2018 in the same area caused by persistent anomalously high wind. Sea ice drift patterns have become more responsive to the atmospheric forcing due to thinning of sea ice cover in this region.

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