Our Experience of Using Soft Bifocal Contact Lenses in Children with Progressive Myopia

The Eye ◽  
2021 ◽  
Vol 23 (2) ◽  
pp. 19-26
Author(s):  
N. N. Slyshalova ◽  
N. V. Khvatova

Introduction. According to the studies, one out of three myopic patients with refraction greater than –6.00 D and an axial length greater than 26 mm is at high risk of facing low vision and loss of sight in the future. According to the results of medical examinations and screenings in carried out in Ivanovo, the prevalence of myopia in primary school children has increased three times during the past twenty years. Myopic children under 7 years old are six times more likely to have myopia progressed to higher degrees than children in which myopia onset took place later (at the age of 11–12 years). Optical interventions for myopia control such as orthokeratology and soft bifocal contact lenses have a strong body of evidence and are well accepted by ophthalmologists.Purpose. The purpose of the present study was to investigate the effect of soft bifocal contact lenses on refraction, accommodation and axial length in children with progressive myopia.Materials and methods. We observed 30 children aged 8–15 years with myopia progression rate of 0.82 D/year and accommodative weakness and instability. We prescribed OKVision PrimaBio Bi-focal design soft bifocal contact lenses (OKVision, Russia) that feature +4.00 D addition power on periphery. The effectiveness was estimated by monitoring refraction, accommodation and axial length every three months within a year.Results. After 12 months of wearing soft bifocal contact lenses, the annual myopia progression rate decreased 4.3 times on average. We were able to stabilize myopia in 50% of the children during the period of monitoring. The use of this intervention had a strong effect on accommodation resulting in an increase of its amplitude and reserve.Conclusion. The use of soft bifocal contact lenses has been proven to have a strong inhibitory effect on myopia progression rate. Myopia stabilization manifested itself as the absence of increase in myopic refraction and axial length as well as normalization of accommodative function.

2018 ◽  
Vol 15 (2S) ◽  
pp. 65-72 ◽  
Author(s):  
M. M. Sitka ◽  
S. G. Bodrova ◽  
N. A. Pozdeyeva

Objective: to determine optimal method of progressive myopia optical correction in children and adolescents.Patients and methods. Conducted 5-year prospective clinical and instrumental examination of 494 children with myopia using orthokeratology lenses, soft contact lenses and glasses. 61 children (the average age 11.7 ± 2.36 years) with myopia –2.87 ± 1.1 D and astigmatism –0.58 ± 0.27 D used orthokeratological lens. 92 children (the average age 12.8 ± 1.51 years) with myopia –3.66 ± 1.07 D, astigmatism –0.53 ± 0.18 D wore soft contact lens. 79 children (the average age 11.52 ± 1.78 years) with myopia –1.59 ± 1.08 D, astigmatism –0.71 ± 0.54 D used glasses with monofocal lenses, with full correction. The control group consisted of 249 children (the average age 9.1 ± 1.14 years) with initial emmetropia. Determination of refraction, subjective and objective determination of accommodation, and axial length of the eye (“IOL-master”) was conducted in children.Results. The maximum progression of myopia was observed in younger children (8–9 years). Correction of myopia with orthokeratology lenses (OKLs) was accompanied by the lowest dynamics of changes in axial length (axial elongation 0,44 ± 0,32 mm) compared to the correction with soft contact lenses (SCLs) (axial elongation 0,73 ± 0,36 mm), spectacle correction (axial elongation 1,39 ± 0,47 mm) and the control group (axial elongation 0,6 ± 0,41 mm). In all children with myopia, at the beginning of the study, there were reduced values reserve of relative accommodation and an objective accommodative response. Correction of myopia with OKLs (p = 0,0002) and SCLs (p = 0,036) provides the normalization of subjective and objective reserve indication of relative accommodation in both age group in comparison of spectacles correction.Conclusion. Correction with orthokeratology lens in children with progressive myopia contributes to the minimum growth length of the eye. Correction of myopia OKLs and MKL improves of subjective and objective indicators of relative accommodation reserve. 


2022 ◽  
Vol 22 (1) ◽  
Author(s):  
Chenghai Weng ◽  
Fei Xia ◽  
Dang Xu ◽  
Xingtao Zhou ◽  
Liangcheng Wu

Abstract Background Myopia is a global public health issue. Controlling myopia progression is a primary focus of myopia studies today. Peripheral retinal myopic defocus is considered the mechanism for reduced myopia progression in orthokeratology studies. The topographic change in the front corneal surface after laser refractive surgery and orthokeratology procedures may appear similar. The purpose of this study was to explore the role of myopic laser ablation on axial length (AL) growth. Methods Myopic patients who underwent monocular excimer laser refractive surgery first in one eye and then in another eye several years later because of myopia occurrence or myopia progression were recruited. The axial length elongation and refraction (spherical equivalent) between the two eyes were observed and compared. Results A total of 8 myopic patients were enrolled in the study. The AL increased from 24.52 ± 0.96 mm to 24.68 ± 1.03 mm but without significance (T = 1.49, P > 0.05) in the ablated eyes. The AL increased significantly from 23.73 ± 0.91 mm to 24.26 ± 0.95 mm in the nonablated eyes (T = 6.76, P < 0.001). The AL elongation of the ablated eyes with 0.16 ± 0.30 mm growth was significantly lower than that of the nonablated eyes with 0.53 ± 0.32 mm growth (T = 8.98, P < 0.001). The spherical equivalent (SE) increased significantly in the ablated eyes (− 0.59 ± 0.21 (D), T = 6.36, P < 0.001) and in the nonablated eyes (− 0.97 ± 0.55 (D), T = 4.91, P < 0.01), and the difference between the two eyes was significant (T = 3.05, P < 0.05). Conclusions The inhibitory effect of myopic laser ablation on AL elongation reported in the limited case studies argues for animal research on its efficacy as a new intervention for myopia progression.


2021 ◽  
Vol 1 (5) ◽  
pp. 148-155

Purpose. The prevalence of myopia is increasing worldwide and its long-term effects can have major impacts on eye health. Paediatric onset of myopia leads to a higher risk for developing high levels of myopia in adulthood. Slowing down or stopping myopia progression is an important task for the future. Material and Methods. Based on a literature review, the latest developments in the field of myopia control for children were summarized. The current study situation for orthokeratology, soft contact lenses, atropine therapy and spectacle lenses for the management of myopia is discussed in detail. Results. Results on the safety and effectiveness of orthokeratology and modified soft contact lenses are exceedingly consistent. Soft multifocal contact lenses, as well as newer spectacle lenses, recently received regulatory approval for myopia control. Studies on the administration of atropine recommend a dosage of 0.01 - 0.05 %. All methods slow down myopia progression and decrease axial length growth of the eye. Side effects, adverse events or discontinuation of treatment only occur in the rarest of cases. Orthokeratology and atropine continue to deliver the best results. Conclusion. From today’s perspective, carrying out myopia control can be recommended with great certainty. The choice of method depends on the individual requirements of each patient, with all methods offering success in reducing myopia progression. In the future, even more advanced contact lens geometries, more precise atropine dosages or improved optics of spectacle lenses will further increase the success of the treatment. Keywords. Progressive myopia, myopia control, children, contact lenses, atropine, spectacle lenses


The Eye ◽  
2019 ◽  
Vol 126 (2019-2) ◽  
pp. 13-20
Author(s):  
Pyotr Nagorsky ◽  
Nikolai Kikhtenko ◽  
Vera Milyukhina

Purpose: To estimate the stabilizing effect of orthokeratology lenses (ortho-K, OK-lenses) on myopia progression by evaluating axial eye growth dynamics and clinical refraction. Material and methods. Ortho-K group consisted of 68 children (135 eyes) aged 7–17 years (mean age 12.2) with progressive myopia (initially -0.75–6.75 D). Observation period varied from 7 to 30 months (mean period 11.68±4.39). All patients used OK-lenses for overnight wear. The control group consisted of 90 patients (180 eyes) with myopia who were prescribed single vision spectacles for vision correction. Comparative analysis was performed for clinical refraction parameters as well as for axial length (AL). The data was obtained with the use of IOL-Master optical biometer (“Carl Zeiss”). Results. The parameters were stable in patients of ortho-K group: axial length, subjective and objective clinical refraction, the required power of corrective lenses. However, the parameters changed significantly in the control group during the observation period: uncorrected visual acuity (UCVA) decreased, the required power of corrective lenses increased, the indices of objective clinical refraction strengthened, annual gradient of progression (AGP) amounted to 0.26±0.19 and 0.16±0,39 mm in patients with low and moderate myopia, respectively. Conclusion. The use of OK-lenses ensures a significant deceleration of myopia progression in children. The results obtained suggest a wider use of ortho-K among pediatric ophthalmologists in their clinical practice as it is an effective preventive and therapeutic method for patients with progressive myopia.


Author(s):  
Neelam Verma

Main aim of this article was a systematic review on causes and management of Myopia progression in children. Myopia is a general disorder, affecting just about one-third of the US popula­tion and over 90% of the population in some East Asian countries. Elevated amounts of myopia are connected with a bigger risk of sight-threatening troubles, such as retinal detachment, choroidal degeneration, cataracts and glaucoma. Slowing the progression of myopia could potentially advantage millions of children in the India. Few approaches used for myopia organize have proven to be useful. Treatment options such as undercorrection of myopia, gas permeable contact lenses, and bifocal or multifocal spectacles have all been proven to be inef­fective for myopia control, although one recent randomized clinical trial using executive top bifocal spectacles on children with progressive myopia has shown to decrease the progression to nearly half of the control subjects. The most effective methods are the use of orthokeratology contact lenses, soft bifocal contact lenses, and pharmaceutical agents such as atropine, timolol or pirenzepine. Keyword: Myopia progression, pharmaceutical agents, lenses, treatment.


2020 ◽  
Author(s):  
DANIELA LOPES-FERREIRA ◽  
Alicia Ruiz-Pomeda ◽  
Belén Peréz-Sanchéz ◽  
António Queirós ◽  
César Villa-Collar

Abstract BackgroundTo compare ocular and corneal inherent aberrations in the naked eyes of randomly selected children fitted with MiSight contact lenses (CL) for myopia control, versus children corrected with single-vision spectacles (control), over a 24-months period.MethodsChildren aged 8 to 12 years, with myopia (-0.75 to -4.00 D sphere) and astigmatism (< -1.00 D cylinder), were assigned to the lens study group (MiSight) or the control group (single-vision spectacles). Axial length (AL) was measured by biometry, corneal RMS (RMS_C), corneal high order RMS (HO_RMS_C), corneal low order RMS (LO_RMS_C), ocular total RMS (RMS_T), ocular total high order RMS (HO_RMS_T), ocular total low order RMS (LO_RMS_T), corneal spherical aberration (SA_C) and ocular total SA (SA_T) were calculated by aberrometric measures at the baseline, and on 12- and 24-months visits. A 5 mm diameter was defined for the analysis in all visits for all subjects. Only the dominant eye was analyzed.ResultsSeventy-four subjects completed the clinical trial: 41 subjects from the MiSight group (age: 11.01 ± 1.23 years) and 33 from the single-vision group (age: 10.12 ± 1.38 years). In the control group, axial length changed significantly (0.444 ± 0.049 mm, p < 0.001) after 2 years. Also RMS_T (0.565 ± 0.199 µm, p = 0.029) and LO_RMS_T (0.461 ± 0.175 µm, p = 0.047) registered significant changes after 24-months in the control group. In the MiSight group, only axial length changed significantly (0.284 ± 0.025 mm, p < 0.001) after 2 years. The SA_C and SA_T did not reveal significant changes between visits or between groups.ConclusionsThe wear of MiSight CL did not induce significant changes in aberrations in anterior cornea and contrary of control group the total ocular RMS and low order RMS did not significantly caused by significantly lower eye growth and myopia progression,Trial registration: ClinicalTrials.gov Identifier: NCT01917110.


2021 ◽  
Vol 1 (4) ◽  
Author(s):  
Srabani Banerjee ◽  
Jennifer Horton

A total of 5 relevant systematic reviews and 7 randomized controlled trials (RCTs) were identified. Myopia progression and axial length elongation was less with omafilcon A (MiSight) contact lenses compared to single-vision lenses (1 RCT; statistical significance of difference was not reported). Myopia progression and axial length elongation was less with defocus incorporated multiple segments spectacle lenses compared to single-vision spectacle lenses (1 RCT; the between-group difference was statistically significant). Myopia progression was less with orthokeratology contact lenses compared to single-vision contact lenses or single-vision lenses (2 systematic reviews and 2 RCTs; between-group difference was statistically significant or statistical significance was not reported) and axial length elongation was less (5 systematic reviews and 2 RCTs; between-group difference was statistically significant or statistical significance was not reported). Myopia progression and axial length elongation was less with multifocal lenses compared with single-vision contact lenses (1 systematic review and 2 RCTs; between-group difference was statistically significant). Findings need to be interpreted in the light of limitations, such as limited quantity and quality of the included primary studies, limited information regarding adverse events, and lack of long-term data. No economic evaluations reporting on the cost-effectiveness of these interventions were identified.


2019 ◽  
Vol 15 (4) ◽  
pp. 439-446 ◽  
Author(s):  
E. N. Iomdina ◽  
E. P. Tarutta ◽  
G. A. Markossian ◽  
A. A. Sianosyan ◽  
P. V. Luzhnov ◽  
...  

Purpose:to evaluate, using transpalpebral rheoophthalmography (TP ROG), the effectiveness of sclera-strengthening and trophic treatment of progressive myopia with a new biologically active chitosan-containing transplant.Patients and methods. 40 children and adolescents with moderate or high progressive myopia, averagely aged 12.6 ± 0.38 years, were examined after receiving low invasive sclera-strengthening surgery on one eye with a biologically active chitosan-containing transplant. The initial refraction of the operated eye was — 6.25 ± 0.23 D, while that of the fellow eye was — 5.85 ± 0.28 D. The yearly gradient of myopia progression averaged 1.10 ± 0.04 D. Hemodynamic parameters were measured using TP ROG) prior to intervention, then 1, 6 and 12 months after intervention. At the same time points, scleral acoustic density (SAD) was determined by analyzing tissue histograms obtained with a multipurpose ultrasound device, VOLUSON 730 Pro «GE».Results. One year after sclera-strengthening treatment, a 4.4-fold reduction of myopia progression rate on the operated eye was noted, supplemented by a 2.2-fold reduction of same on the fellow eye. Stabilization of refraction was accompanied by an increase of SAD: 6 months after the surgery, SAD was averagely 19.7 conventional units higher than the original figure in the posterior pole of the operated eye, and 16.2 conventional units higher in the equatorial area. One year after the surgery, the figures were, respectively, 15.9 (p < 0.05) and 14.0 conventional units (p < 0.01). The rheographic index of TP ROG increased with regard to the initial value by 139 % after one month, by 69.8 % after 6 months, and by 34.6 % after 1 year. On fellow eyes, the index also tended to increase: by 123.3 % after 1 month, by 65.2 after 6 months, and by the end of the follow-up period it exceeded the original value by 28.7 %, which is an evidence of a pronounced trophic effect of sclera-strengthening myopia treatment with chitosan not only on the operated eye but also (to a lesser extent) on the fellow eye.Conclusion. TP ROG is an effective evaluation method of sclera-strengthening treatment of progressive myopia. This method can also be used to study eye hemodynamics in a variety of ophthalmic pathologies, including those managed in pediatric clinical practice. 


2021 ◽  
pp. 875-881
Author(s):  
Nir Erdinest ◽  
Naomi London ◽  
Nadav Levinger ◽  
Itay Lavy ◽  
Eran Pras ◽  
...  

This retrospective case series demonstrates the combination of 0.05% atropine with MiSight<sup>®</sup> 1 day (Cooper vision, Sar Ramon, CA, USA) in rapid progression of myopia of 4 children. MiSight<sup>®</sup> 1 day is a peripheral defocus, center-distance soft contact lens and is effective at controlling moderate progression of myopia during the course of 1 year. The current case series included 2 females and 2 males with an average age of 9.68 ± 0.26 years and an average axial length of 24.81 ± 0.92 mm. Their myopic progression during the previous year was −1.45 ± 0.27 D. The children had not attempted any myopia control thus far. This relatively high increase prompted a combination treatment of daily instillation of 0.05% atropine and MiSight, a daily replacement soft contact lens. Cycloplegic refraction and a slit-lamp evaluation were performed every 6 months to confirm no adverse reactions or staining was present. The 8-item contact lens dry eye questionnaire (CLDEQ-8) score of these children was 10.66 ± 1.52. The average myopia progression at the end of 1 year decreased to −0.41 ± 0.11 D, and the average axial length increase was 0.28 ± 0.08 mm. To the best of the authors’ knowledge, this is the first published study showing a combination of 0.05% atropine and peripheral defocus soft contact lenses indicating efficacy at controlling moderate myopia progression.


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