Unsupervised Clustering of Continuous Ambient Noise Data to Get Higher Signal Quality in Seismic Surveys

Seismic interferometry has been shown to extract body wave arrivals from ambient noise seismic data. However, surface waves dominate ambient noise data, so cross-correlating and stacking all available data may not succeed in extracting body wave arrivals. A better strategy is to find portions of the data in which body wave energy dominates and to process only those portions. One challenge is that passive seismic recordings comprise huge volumes of data, so identifying portions with strong body-wave energy could be difficult or time-consuming. We use spatio-temporal features, calculated with data recorded by all receivers together, to perform unsupervised clustering. Using data recorded by a dense seismic array in Sweetwater, TX we were able to identify five clusters, representing a subsets of the complete dataset that contain similar features, and extract a 7 km/s body wave arrival from one cluster. This arrival did not emerge when we performed the same cross-correlation and stacking regimen on the entire dataset.

Protein Appetite at the Interface between Nutrient Sensing and Physiological Homeostasis

Feeding behavior is guided by multiple competing physiological needs, as animals must sense their internal nutritional state and then identify and consume foods that meet nutritional needs. Dietary protein intake is necessary to provide essential amino acids and represents a specific, distinct nutritional need. Consistent with this importance, there is a relatively strong body of literature indicating that protein intake is defended, such that animals sense the restriction of protein and adaptively alter feeding behavior to increase protein intake. Here, we argue that this matching of food consumption with physiological need requires at least two concurrent mechanisms: the first being the detection of internal nutritional need (a protein need state) and the second being the discrimination between foods with differing nutritional compositions. In this review, we outline various mechanisms that could mediate the sensing of need state and the discrimination between protein-rich and protein-poor foods. Finally, we briefly describe how the interaction of these mechanisms might allow an animal to self-select between a complex array of foods to meet nutritional needs and adaptively respond to changes in either the external environment or internal physiological state.

Politics and principles: The impact of counterterrorism measures and sanctions on principled humanitarian action

For some time, the impact of counterterrorism (CT) measures and sanctions on humanitarian action did not attract the attention that it merited. However, owing to a surge in awareness of this issue over the past two years, the fact that CT measures and sanctions can have negative consequences for principled humanitarian action is now widely accepted by a broad range of actors, and is supported by a strong body of research identifying and analyzing these impacts. This article adds to this existing work by examining recent developments related to this issue. It looks at the impact of growing risk aversion in relation to CT measures and sanctions among donors, humanitarian organizations and other actors on principled humanitarian action, and highlights recent efforts to address and mitigate these impacts. The central argument is that CT and sanctions risks cannot be eliminated from humanitarian action. As such, policy change is needed to protect principled humanitarian action from further detrimental impacts and to ensure that people can access the assistance they need, regardless of where they are located.

Method of biocontrol of vehicle driver fatigue

This article describes an example of negligence of drivers transporting passengers and methods of solving it using modern inventions. One of these troubles is driving a car and moving passengers by taxi driver in a tired state. Since not every driver can correctly assess their psycho-physical condition, so to do this, scientists began to create devices for tracking human behavior when he drives vehicle. The purpose of implementing driver fatigue monitoring systems is to ensure road safety and preserve lives and property of citizens. The use of these systems is to facilitate the work of emergency services and taxi company owners, taxi drivers and their passengers. In our article we want to touch on the problem of overwork, specifically taxi drivers, since their work activity is socially significant and non-compliance with the norms of work and rest periods can lead to tragic consequences. Modern taxi drivers often rely on a strong body of car and electronic gadgets in an unexpected situation on the road. Therefore, when driving a car, despite being overworked, they allow themselves to relax beyond the limit and dont react in time if an emergency occurs. We have studied options for implementing driver fatigue monitoring systems and offer to install them on a taxi car.

Analysis on the Improvement Strategies of College Students’ Sub-Health Psychological Status from the Perspective of Music Education

Objectives: College stage is a critical period for students to become mature and independent, and it is also a period of rapid changes in physical and mental development. Methods: They need not only good ideological and moral qualities, scientific and cultural qualities and strong body, but also good psychological characteristics. With the implementation of the enrollment expansion policy in colleges and universities, the number of college students has increased sharply, and the mental health problems of college students have become more prominent. Results: Many students are in a state of psychological abnormality, but they have not reached the degree of illness, that is, mental sub-health state. In the current high-speed development society, college students are facing more pressures and challenges due to academic, employment, economic, emotional and other comprehensive factors such as uncoordinated interpersonal relationships. Music education, as an aesthetic education, plays a unique role in adjusting the sub-health psychology of college students. Conclusion: This paper discusses the promotion of college music education to the development of college students’ mental health, and analyzes the methods of improving college students’ mental sub-health state by college music education.

What Is the Role of Steroids for Septic Shock in 2021?

Corticosteroids have been used for decades in the adjunctive treatment of severe infections in intensive care. The most frequent scenario in intensive care is in septic shock, where low doses of glucocorticoids appear to restore vascular responsiveness to norepinephrine. There is a strong body of evidence suggesting that hydrocortisone reduces time on vasopressor, and may modulate the immune response. In this review, we explore the current evidence supporting the use of corticosteroids in septic shock, its benefits, and potential harms. In addition to landmark clinical trials, we will also describe new frontiers for the use of corticosteroids in septic shock which should be explored in future studies.

CELL HEALTH LEARNING BASED ON DZIKRULLOH SPIRITUAL PRACTICE “HE NING CIPTO METAPHYSICS MEDITATION”, TO BUILD A STRONG BODY IMMUNITY SYSTEM

This study aimed to describe the implementation of the Spiritual Practice-Based Learning Approach to Metaphysics Meditation "He Ning Cipto" in the Cell-Level Life course to build the student's immune system during the covid-19 pandemic. This study involved three classes of 2018 class students with a total of 90 people. This quasi-experimental research uses a "one shot case study" as a research design where there is only a treatment class without control. Data collection methods in this study include observation, tests and surveys in order to obtain data on the implementation of learning, mastery of concepts, meditation skills, and mental health. The results showed that the implementation of the learning carried out had fulfilled the syntax and obtained the dominant learning management assessment score mode of 4 from the total existing meetings. The learning outcomes test from 3 classes with 4 study topics (Cell Structure and Function, Cell Health Concepts, Body Immune System, Cipto Silent Meditation) in 7 meetings showed that students' mastery of concepts could be achieved maximally both individually and classically with a percentage of completeness of 95, 56%. Based on rewriting data and diaries, Cipto's Silent Meditation skills can be practiced well according to the recommended instructions and procedures. Students' rewriting scores ranged from 78 to 100, while for student diaries they received a minimum score of 80 and a maximum of 100. The questionnaire responses given showed high Mental Attitude Health (KSM) results of 96%, High Cell/Body Health (KST) of 86% and the Happiness Scale Index is in the high category (above 34, 4) with A level between 46-50 at 29%, Level B between 40-45 at 66% and C between 34-39 at 6%. Overall, it can be concluded that this research has helped students in learning and gaining an understanding of the concept of cell health and the immune system, as well as developing silent meditation skills, to build a strong immune system for students and actors in achieving a level of mental health and mental attitude. good dohir cells/body, and pure soul happiness is born as a result of a sense of faith, and evidence of obedience and gratitude to Allah SWT for all His blessings, then the practice of meditation has an impact as a form of self-protection from various kinds of diseases including the Covid-19 virus.

Our Experience of Using Soft Bifocal Contact Lenses in Children with Progressive Myopia

Introduction. According to the studies, one out of three myopic patients with refraction greater than –6.00 D and an axial length greater than 26 mm is at high risk of facing low vision and loss of sight in the future. According to the results of medical examinations and screenings in carried out in Ivanovo, the prevalence of myopia in primary school children has increased three times during the past twenty years. Myopic children under 7 years old are six times more likely to have myopia progressed to higher degrees than children in which myopia onset took place later (at the age of 11–12 years). Optical interventions for myopia control such as orthokeratology and soft bifocal contact lenses have a strong body of evidence and are well accepted by ophthalmologists.Purpose. The purpose of the present study was to investigate the effect of soft bifocal contact lenses on refraction, accommodation and axial length in children with progressive myopia.Materials and methods. We observed 30 children aged 8–15 years with myopia progression rate of 0.82 D/year and accommodative weakness and instability. We prescribed OKVision PrimaBio Bi-focal design soft bifocal contact lenses (OKVision, Russia) that feature +4.00 D addition power on periphery. The effectiveness was estimated by monitoring refraction, accommodation and axial length every three months within a year.Results. After 12 months of wearing soft bifocal contact lenses, the annual myopia progression rate decreased 4.3 times on average. We were able to stabilize myopia in 50% of the children during the period of monitoring. The use of this intervention had a strong effect on accommodation resulting in an increase of its amplitude and reserve.Conclusion. The use of soft bifocal contact lenses has been proven to have a strong inhibitory effect on myopia progression rate. Myopia stabilization manifested itself as the absence of increase in myopic refraction and axial length as well as normalization of accommodative function.

A Mouse Model of Shiftwork Reveals Sex-Specific Impairments in Circadian Behavior and Reproductive Tissue Timekeeping

Approximately 21 million Americans are employed in nighttime or rotating shiftwork, which is linked with numerous health risks, including reduced reproductive success. While there is a strong body of clinical evidence associating shift workers with deficits in fertility, very little is known about the mechanisms by which shiftwork produces reproductive dysfunction. One important feature of shiftwork is extensive exposure to light at night. Light is one of the strongest timing cues for the circadian system, where exposure to mistimed light (light at night) can disrupt timekeeping throughout the body, leading to a mistiming of physiological processes and resulting in disease development. Our goal is to determine if a light-based model of rotating shiftwork (shift-light), composed of an alternating 6 hour phase advance or delay every 4 days for 5-10 weeks, disrupts circadian rhythms in the reproductive hypothalamic-pituitary-gonadal (HPG) axis, leading to mis-timed tissue rhythms and reduced fertility. We hypothesize that shift-light disrupts wheel running behavior and underlying cellular circadian rhythms in the HPG axis, resulting in reduced reproductive function. Using the validated circadian Per2:luciferase reporter mice, we assessed wheel-running behavior and Per2:luciferase rhythms in tissue explants from males and females. Behavioral data revealed that both sexes adapt their wheel running to shift-light paradigm; however, females, but not males, displayed a significant deficit in their ability to entrain to phase advances following 4 shifts. This sex-specific disruption was supported by preliminary tissue explant Per2:luciferase rhythms, which suggest that shift-light alters tissue level circadian phase synchrony in female, but not male, HPG axis tissues. Importantly, females exhibited shortened estrous cycling during shift-light, suggesting the altered HPG axis synchrony could be directly impacting reproductive function. We are currently working to extend this work to determine how this desynchrony impacts hormone release, including luteinizing hormone and follicle stimulating hormone. Together, this work provides insight into how shiftwork may influence circadian rhythms in reproductive tissues and suggests that females may have increased vulnerability to reproductive deficits from shiftwork.

Inflammatory Biomarkers and Chronic Diseases: The Link to COVID-19.

1. Abstract The COVID-19 disease and pandemic eruption have caused a major concern for patients and healthcare systems globally. Immunological therapies are among the areas that require a lot of attention as the immunological consequences of the infection are neither well defined nor well understood. All medical reports indicate that severe acute respiratory syndrome-coronavirus-2 infection has a fatal outcome often results from alveolar injury that impedes airway capacity and multi-organ failure. Both of these complications are associated with the hyper production of cytokines that is known by the term cytokine storm and also called cytokine release syndrome. Strong body of clinical reports show that both mild and severe forms of disease result in cytokine secretion through changes in circulating leukocyte subsets. This is accompanied by elevated level of cytokines production. The milieu of cytokines produced includes IL-6, IL-1β, IL-10, TNF, GM-CSF, IP-10 (IFN-induced protein 10), IL-17, MCP-1, MCP-3 and IL-1ra. With no surprise immune-therapies that target the immune response and curtail the cytokine storm in coronavirus 2019 (COVID-19) patients have become a focus of recent clinical trials. In this mini-review we are also highlighting the importance of monitoring closely the levels of the cytokines as a true measure for the patient`s status and immunity level.