scholarly journals Mapping low-frequency field potentials in cortico-hippocampal brain slices with high-resolution CMOS-MEAs

Author(s):  
Stefano Zordan ◽  
Davide Lonardoni ◽  
Alessandro Maccione ◽  
Luca Berdondini
Author(s):  
P. A. Marsh ◽  
T. Mullens ◽  
D. Price

It is possible to exceed the guaranteed resolution on most electron microscopes by careful attention to microscope parameters essential for high resolution work. While our experience is related to a Philips EM-200, we hope that some of these comments will apply to all electron microscopes.The first considerations are vibration and magnetic fields. These are usually measured at the pre-installation survey and must be within specifications. It has been our experience, however, that these factors can be greatly influenced by the new facilities and therefore must be rechecked after the installation is completed. The relationship between the resolving power of an EM-200 and the maximum tolerable low frequency interference fields in milli-Oerstedt is 10 Å - 1.9, 8 Å - 1.4, 6 Å - 0.8.


Symmetry ◽  
2021 ◽  
Vol 13 (5) ◽  
pp. 900
Author(s):  
Hao Cheng ◽  
Manling Ge ◽  
Abdelkader Nasreddine Belkacem ◽  
Xiaoxuan Fu ◽  
Chong Xie ◽  
...  

Although the power of low-frequency oscillatory field potentials (FP) has been extensively applied previously, few studies have investigated the influence of conducting direction of deep-brain rhythm generator on the power distribution of low-frequency oscillatory FPs on the head surface. To address this issue, a simulation was designed based on the principle of electroencephalogram (EEG) generation of equivalent dipole current in deep brain, where a single oscillatory dipole current represented the rhythm generator, the dipole moment for the rhythm generator’s conducting direction (which was orthogonal and rotating every 30 degrees and at pointing to or parallel to the frontal lobe surface) and the (an)isotropic conduction medium for the 3D (a)symmetrical brain tissue. Both the power above average (significant power value, SP value) and its space (SP area) of low-frequency oscillatory FPs were employed to respectively evaluate the strength and the space of the influence. The computation was conducted using the finite element method (FEM) and Hilbert transform. The finding was that either the SP value or the SP area could be reduced or extended, depending on the conducting direction of deep-brain rhythm generator flowing in the (an)isotropic medium, suggesting that the 3D (a)symmetrical brain tissue could decay or strengthen the spatial spread of a rhythm generator conducting in a different direction.


2013 ◽  
Vol 9 (S303) ◽  
pp. 464-466
Author(s):  
M. Rickert ◽  
F. Yusef-Zadeh ◽  
C. Brogan

AbstractWe analyze a high resolution (114″ × 60″) 74 MHz image of the Galactic center taken with the Very Large Array (VLA). We have identified several absorption and emission features in this region, and we discuss preliminary results of two Galactic center sources: the Sgr D complex (G1.1–0.1) and the Galactic center lobe (GCL).The 74 MHz image displays the thermal and nonthermal components of Sgr D and we argue the Sgr D supernova remnant (SNR) is consistent with an interaction with a nearby molecular cloud and the location of the Sgr D Hii region on the near side of the Galactic center. The image also suggests that the emission from the eastern side of the GCL contains a mixture of both thermal and nonthermal sources, whereas the western side is primarily thermal.


Author(s):  
Ting Qing ◽  
Shupeng Li ◽  
Lihan Wang ◽  
Xiaohu Tang ◽  
Ping Li ◽  
...  

Author(s):  
N. M. DATSENKO ◽  
◽  
D. M. SONECHKIN ◽  
B. YANG ◽  
J.-J. LIU ◽  
...  

The spectral composition of temporal variations in the Northern Hemisphere mean surface air temperature is estimated and compared in 2000-year paleoclimatic reconstructions. Continuous wavelet transforms of these reconstructions are used for the stable estimation of energy spectra. It is found that low-frequency parts of the spectra (the periods of temperature variations of more than 100 years) based on such high-resolution paleoclimatic indicators as tree rings, corals, etc., are similar to the spectrum of white noise, that is never observed in nature. This seems unrealistic. The famous reconstruction called “Hockey Stick” is among such unrealistic reconstructions. Reconstructions based not only on high-resolution but also on low-resolution indicators seem to be more realistic, since the low-frequency parts of their spectra have the pattern of red noise. They include the “Boomerang” reconstruction showing that some warm periods close to the present-day one were observed in the past.


1999 ◽  
Vol 82 (4) ◽  
pp. 2020-2023 ◽  
Author(s):  
Michael Pasternack ◽  
Mathias Boller ◽  
Belinda Pau ◽  
Matthias Schmidt

We have recently found that GABAC receptor subunit transcripts are expressed in the superficial layers of rat superior colliculus (SC). In the present study we used immunocytochemistry to demonstrate the presence of GABAC receptors in rat SC at protein level. We also investigated in acute rat brain slices the effect of GABAA and GABAC receptor agonists and antagonists on stimulus-evoked extracellular field potentials in SC. Electrical stimulation of the SC optic layer induced a biphasic, early and late, potential in the adjacent superficial layer. The late component was completely inhibited by 6-cyano-7-nitroquinoxaline-2,3-dione or CoCl2, indicating that it was generated by postsynaptic activation. Muscimol, a potent GABAA and GABAC receptor agonist, strongly attenuated this postsynaptic potential at concentrations >10 μM. In contrast, the GABAC receptor agonist cis-aminocrotonic acid, as well as muscimol at lower concentrations (0.1–1 μM) increased the postsynaptic potential. This increase was blocked by (1,2,5,6-tetrahydropyridine-4-yl)methylphosphinic acid, a novel competitive antagonist of GABAC receptors. Our findings demonstrate the presence of functional GABAC receptors in SC and suggest a disinhibitory role of these receptors in SC neuronal circuitry.


2000 ◽  
Vol 36 (5) ◽  
pp. 3096-3098 ◽  
Author(s):  
K. Sivasubramaniam ◽  
S. Salon ◽  
M.V.K. Chari

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