Forward masking in a bottlenose dolphin Tursiops truncatus : Dependence on azimuthal positions of the masker and test sources

Forward masking was investigated by the auditory evoked potentials (AEP) method in a bottlenose dolphin Tursiops truncatus using stimulation by two successive acoustic pulses (the masker and test) projected from spatially separated sources. The positions of the two sound sources either coincided with or were symmetrical relative to the head axis at azimuths from 0 to ±90°. AEPs were recorded either from the vertex or from the lateral head surface next to the auditory meatus. In the last case, the test source was ipsilateral to the recording side, whereas the masker source was either ipsi- or contralateral. For lateral recording, AEP release from masking (recovery) was slower for the ipsi- than for the contralateral masker source position. For vertex recording, AEP recovery was equal both for the coinciding positions of the masker and test sources and for their symmetrical positions relative to the head axis. The data indicate that at higher levels of the auditory system of the dolphin, binaural convergence makes the forward masking nearly equal for ipsi- and contralateral positions of the masker and test.

Angle-Tuned Coils: Enabling Building Blocks for High Performance and Multisite TMS Systems

Objective: A novel angle-tuned ring coil is proposed for improving the depth-spread performance of Transcranial Magnetic Stimulation (TMS) coils and serve as the building blocks for high-performance composite coils and multisite TMS systems. Approach: Improving depth-spread performance by reducing field divergence through creating a more elliptical emitted field distribution from the coil. To accomplish that, instead of enriching the Fourier components along the planarized (x-y) directions, which requires different arrays to occupy large brain surface areas, we worked along the radial (z) direction by using tilted coil angles and stacking coil numbers to reduce the divergence of the emitted near field without occupying large head surface areas. The emitted electric field distributions were theoretically simulated in spherical and real human head models to analyze the depth-spread performance of proposed coils and compare with existing figure-8 coils. The results were then experimentally validated with field probes and in-vivo animal tests. Main Results: The proposed "angle-tuning" concept improves the depth-spread performance of individual coils with a significantly smaller footprint than existing and proposed coils. For composite structures, using the proposed coils as basic building blocks simplifies the design and manufacturing process and helps accomplish a leading depth-spread performance. In addition, the footprint of the proposed system is intrinsically small, making them suitable for multisite stimulations of inter and intra-hemispheric brain regions with an improved spread and less electric field divergence. Significance: Few brain functions are operated by isolated single brain regions but rather by coordinated networks involving multiple brain regions. Simultaneous or sequential multisite stimulations may provide tools for mechanistic studies of brain functions and the treatment of neuropsychiatric disorders. The proposed AT coil goes beyond the traditional depth-spread tradeoff rule of TMS coils, which provides the possibility of building new composite structures and new multisite TMS tools.

Analysis of Psychological and Emotional Tendency Based on Brain Functional Imaging and Deep Learning

When facing various pressures, human beings will have different degrees of bad psychological emotions, especially depression and anxiety. How to effectively obtain psychological data signals and use advanced intelligent technology to identify and make decisions is a research hotspot in psychology and computer science. Therefore, a personal emotional tendency analysis method based on brain functional imaging and deep learning is proposed. Firstly, the EEG forward model is established according to functional magnetic resonance imaging (fMRI), and the transfer matrix from the signal source at the cerebral cortex to the head surface electrode is obtained. Therefore, the activation results of fMRI emotional experiment can be mapped to the three-layer head model to obtain the EEG topographic map reflecting the degree of emotional correlation. Then, combining data enhancement (Mixup) with three-dimensional convolutional neural network (3D-CNN), an emotion-related EEG topographic map classification method based on M-3DCNN is proposed. Mixup is used to generate virtual data, the original data and virtual data are used to train the network together, the number of training samples is expanded, the overfitting phenomenon of 3D-CNN is alleviated, and 3D-CNN is used for feature extraction and classification. Experimental data analysis shows that, compared with traditional methods, the proposed method can retain emotion related EEG signals to a greater extent and obtain a higher accuracy of emotion five classifications under the same feature dimension.

Estimation of fatigue life parameters of an Alumino Thermic weld on UIC60 rail joint using LEFM

At wheel track contact point, the high stress concentration, poor weld quality, and heterogeneity of weld material are the main factors that cause fatigue crack on any rail weld. Railway network agencies are concerned about the safety of the railway track when it comes to detecting and fixing weld faults to avoid vehicle derailment and loss of lives. This study analysed a numerical simulation of fatigue crack and its evolution under loaded service condition. A 3-D CAD wheel rail weld assembly model was built to study an AT welded joint under fatigue, and for stress concentration factor (SIF) calculation. The results are found by inserting a semi elliptical crack on the rail weld head surface with ANSYS, and then numerical simulation has been performed to get the different three modes of SIF at rail weld crack. The analysis findings data was recorded with critical fracture parameters of SIFs and its number of cycles to failure using LEFM technique and respective results have been plotted. With ANSYS the stress intensity on a crack will be resulted. By using numerical method, the critical crack size and number of cycle load with fatigue life of rail would be determined. The numbers of rail weld inspection per year has been determine by using the maximum number of cycle. The aim of this paper is to develop an effective inspection and maintenance frequency based on rolling contact surfaces crack propagation analyse. This will help to prevent the occurrence of rail failure by taking the required action at the right time, and extend the rail life expectancy, reduce the rail maintenance work and its cost.

Intensity and Predilection of Helminth Parasites of the Red Snapper (Lutjanus argentimaculatus)

Marine fish, particularly the red snappers, are often exposed to helminth parasitic infestation. As a result of the parasitic infestation, the fish population, the fish weight, and the morphological changes in the fish are shrinking. The present research aimed to find out the intensity and predilection of the helminth ectoparasites over the infection of the red snapper (Lutjanus argentimaculatus) and employed the survey method for this purpose. The sampling was carried out by the purposive sampling technique. The sample obtained consisted of 30 fish, 20% of the total red snapper population of 150 fish reared in the floating net cages of Balai Besar Perikanan Budidaya Laut Lampung. The intensity of the fish infestation by a mixture of Haliotrema epinepheli and Benedenia epinepheli was 132.5 individuals/fish. Neobenedenia girellae and Haliotrema epinepheli infected fish with an intensity of 149.41 individuals/fish. The 66.7% of Benedenia epinepheli had a predilection for the dorsal fin, and 33.3% for the anal fin. In Neobenedenia girellae, 57.1% had a predilection for the body surface, 37.2% for the head surface, and 5.7% for the dorsal fin. In conclusion, all sampled fish were positively infected with helminth ectoparasites, including Neobenedenia girellae, Haliotrema epinepheli, and Benedenia epinepheli.

Using an Improved Differential Evolution for Scheduling Optimization of Dual-Gantry Multi-Head Surface-Mount Placement Machine

The difference between dual-gantry and single-gantry surface-mount placement (SMP) machines is that dual-gantry machines exhibit higher complexity and more problems due to their additional gantry robot, such as component allocation and collision. This paper presents algorithms to prescribe the assembly operations of a dual-gantry multi-head surface-mount placement machine. It considers five inter-related problems: (i) component allocation; (ii) automatic nozzle changer assignment; (iii) feeder arrangement; and (iv) pick-and-place sequence; it incorporates a practical restriction related to (v) component height. The paper proposes a solution to each problem: (i) equalizing “workloads” assigned to the gantries, (ii) using quantity ratio method, (iii) using two similarity measurement mechanisms in a modified differential evolution algorithm with a random-key encoding mapping method that addresses component height restriction, (iv) and a combination of nearest-neighbor search and 2-opt method to plan each placing operation. This study reports an experiment that involved the processing of 10 printed circuit boards and compared the performance of a modified differential evolution algorithm with well-known algorithms including differential evolution, particle swarm optimization, and genetic algorithm. The results reveal that the number of picks, moving distance of picking components, and total assembly time with the modified differential evolution algorithm are less than other algorithms.

Corneal hysteresis as a risk factor for optic nerve head surface depression and retinal nerve fiber layer thinning in glaucoma patients

To evaluate the role of corneal hysteresis (CH) as a risk factor for progressive ONH surface depression and RNFL thinning measured by confocal scanning laser ophthalmoscopy (CSLO) and spectral-domain optical coherence tomography (SD-OCT), respectively in glaucoma patients. Prospective study. A total of 146 eyes of 90 patients with glaucoma were recruited consecutively. The CH measurements were acquired at baseline and 4-months interval using the Ocular Response Analyzer (Reichert Instruments, Depew, NY). Eyes were imaged by CSLO (Heidelberg Retinal Tomograph [HRT]; Heidelberg Engineering, GmbH, Dossenheim, Germany) and SD-OCT (Cirrus HD-OCT; Carl Zeiss Meditec AG, Dublin, CA) at approximately 4-month intervals for measurement of ONH surface topography and RNFL thickness, respectively. Significant ONH surface depression and RNFL thinning were defined with reference to Topographic Change Analysis (TCA) with HRT and Guided Progression Analysis (GPA) with Cirrus HD-OCT, respectively. Multivariate cox proportional hazards models were used to investigate whether CH is a risk factor for ONH surface depression and RNFL progression after adjusting potential confounding factors. All patients with glaucoma were followed for an average of 6.76 years (range, 4.56–7.61 years). Sixty-five glaucomatous eyes (44.5%) of 49 patients showed ONH surface depression, 55 eyes (37.7%) of 43 patients had progressive RNFL thinning and 20 eyes (13.7%) of 17 patients had visual field progression. In the cox proportional hazards model, after adjusting baseline diastolic IOP, CCT, age, baseline disc area and baseline MD, baseline CH was significantly associated with ONH surface depression and visual field progression (HR = 0.71, P = 0.014 and HR = 0.54, P = 0.018, respectively), but not with RNFL thinning (HR = 1.03, P = 0.836). For each 1-mmHg decrease in baseline CH, the hazards for ONH surface depression increase by 29%, and the hazards for visual field progression increase by 46%. The CH measurements were significantly associated with risk of glaucoma progression. Eyes with a lower CH were significantly associated with an increased risk of ONH surface depression and visual field progression in glaucoma patients.

Stress-Distribution Pattern Across the Glenohumeral Joint in Collegiate and Professional Baseball Players: A Computed Tomography Osteoabsorptiometry Study

Background: The influence of long-term loading conditions on the articular surfaces of the glenohumeral joint can be determined by measuring stress-distribution patterns. Long-term pitching activity changes the stress distribution across the glenohumeral joint surface; however, the influence of competitive level on stress-distribution patterns remains unclear. Purpose: To use computed tomography (CT) osteoabsorptiometry (CTOAM) to evaluate the distribution of subchondral bone density across the glenohumeral joint in collegiate and professional baseball players as well as to determine the effects of pitching activity on the articular surfaces. Study Design: Descriptive laboratory study. Methods: We evaluated 73 shoulders in 50 baseball players. CT imaging data were obtained from the dominant-side shoulder of 12 professional pitchers (PP group) and 15 professional fielders (PF group). CT imaging data were also obtained from both shoulders of 12 asymptomatic collegiate pitchers (CP group) and 11 collegiate fielders (CF group). The pattern of distribution of subchondral bone density across the articular surfaces of each glenohumeral joint was assessed by CTOAM. As a measure of bone density, the mean Hounsfield units (HU) were obtained for each joint surface, and the absolute values of the dominant shoulder were compared for each group. Results: Stress-distribution patterns over the articular surfaces differed between the dominant and nondominant sides in the CP group as well as between both collegiate groups versus the PP group. In the CP group, the mean HU of the humeral head surface were greater on the nondominant versus dominant side ( P = .035). On the dominant side, the mean HU of the humeral head surface and glenoid were greater in the CP versus the PP group ( P = .001 and .027, respectively). Conclusion: Stress distribution on the articular surface of the glenohumeral joint was affected by pitching ability and competitive level. Our analysis indicates that the traction force on the glenohumeral joint surface might be greater than compression force during pitching. Clinical Relevance: The present findings suggest that pitching activity results in low stress to the articular surfaces of the glenohumeral joint. This supports the notion that mechanical conditions play a crucial role in the etiology of disorders specific to pitching activity.