Detailed Computational Modeling of the Developmental Self-Organization of Neuronal Structure and Function

It is valuable to be researched in the application of science of complexity to the forest ecosystem. Forest ecosystem is an adaptive complex system which is suggested to be at the edge of chaos or at the criticality. The inner interaction of a forest ecosystem is the main driving force for the self-organization, complexity and order in the forest ecosystem. Forest ecosystem complexity is one of the research frontiers of ecological and evolutionary problems presently. The application of science of complexity to the forest ecosystem complexity studies, its concept, background, methodology and theory are briefly introduced. The forest ecosystem complexity is defined as the structure and function diversity, self-organization and the order of an ecosystem. Its main methods include the cellular automaton, genetic algorithm, game theory, complex network, etc. This paper has discussed mechanism and development of forest ecosystem complexity, by applying the principle and methods of science of complexity, which is a new approach for understanding ecological and evolutionary problems.

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Dietary ω-3 fatty acid supplementation for optimizing neuronal structure and function

Molecular Nutrition & Food Research ◽

10.1002/mnfr.200900201 ◽

2010 ◽

Vol 54 (4) ◽

pp. 447-456 ◽

Cited By ~ 57

Author(s):

Stephen C. Heinrichs

Keyword(s):

Fatty Acid ◽

Structure And Function ◽

Neuronal Structure ◽

Fatty Acid Supplementation ◽

Acid Supplementation ◽

And Function

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Wiring optimization can relate neuronal structure and function

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.0506806103 ◽

2006 ◽

Vol 103 (12) ◽

pp. 4723-4728 ◽

Cited By ~ 339

Author(s):

B. L. Chen ◽

D. H. Hall ◽

D. B. Chklovskii

Keyword(s):

Structure And Function ◽

Neuronal Structure ◽

And Function ◽

Wiring Optimization

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The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease

Frontiers in Pharmacology ◽

10.3389/fphar.2021.775034 ◽

2021 ◽

Vol 12 ◽

Author(s):

Anna Nowak ◽

Klaudyna Kojder ◽

Joanna Zielonka-Brzezicka ◽

Jacek Wróbel ◽

Mateusz Bosiacki ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Supportive Therapy ◽

Cognitive Disorders ◽

Structure And Function ◽

Neuronal Structure ◽

Brain Areas ◽

Therapeutic Protocol ◽

Common Causes ◽

And Function

Alzheimer’s disease, a neurodegenerative disease, is one of the most common causes of dementia if elderly people worldwide. Alzheimer’s disease leads to the alienation of individuals and their exclusion from social and professional life. It is characterized mainly by the degradation of memory and disorientation, which occurs as a result of the loss of neuronal structure and function in different brain areas. In recent years, more and more attention has been paid to use in the treatment of natural bioactive compounds that will be effective in neurodegenerative diseases, including Alzheimer’s disease. G. biloba L. and its most frequently used standardized extract (EGb 761), have been used for many years in supportive therapy and in the prevention of cognitive disorders. The paper presents an overview of reports on the pathogenesis of Alzheimer’s disease, as well as a summary of the properties of G. biloba extract and its effects on the possible pathogenesis of the disease. By exploring more about the pathogenesis of the disease and the benefits of G. biloba extract for patients with Alzheimer’s disease, it will be possible to create an individualized therapeutic protocol to optimize the treatment.

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Review on various factors responsible for neurodegenerative disorders

GSC Biological and Pharmaceutical Sciences ◽

10.30574/gscbps.2021.16.1.0203 ◽

2021 ◽

Vol 16 (1) ◽

pp. 126-132

Author(s):

Harshwardhan J Tembhurnikar ◽

Neha D Thool ◽

Rasika J Patil ◽

Ranjita K Das

Keyword(s):

Oxidative Stress ◽

Nervous System ◽

Neurodegenerative Disorders ◽

Protein Misfolding ◽

Critical Role ◽

Structure And Function ◽

Neuronal Structure ◽

Pathophysiological Mechanisms ◽

Neurological Illnesses ◽

And Function

Neurodegenerative disorders are nervous system disorders that result in the loss of neuronal structure and function. As shown in Alzheimer's and Parkinson's disease, these changes cause a loss of various capacities, including cognition and mobility. Several factors have been discovered to play a critical role in the etiology of common neurological illnesses, including oxidative stress and protein misfolding. It's still unclear if these factors cause or contribute to the progression of the illnesses. Despite efforts to understand the molecular and pathophysiological mechanisms behind these pathways, many aspects remain unknown. The goal of this review is to investigate the numerous factors linked to neurodegeneration.

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The Cytoskeleton and Its Roles in Self-Organization Phenomena: Insights from Xenopus Egg Extracts

Cells ◽

10.3390/cells10092197 ◽

2021 ◽

Vol 10 (9) ◽

pp. 2197

Author(s):

Zachary M. Geisterfer ◽

Gabriel Guilloux ◽

Jesse C. Gatlin ◽

Romain Gibeaux

Keyword(s):

Experimental System ◽

Structure And Function ◽

Self Organization ◽

African Clawed Frog ◽

Egg Extracts ◽

Xenopus Egg ◽

The Many ◽

And Function ◽

Xenopus Egg Extracts ◽

Clawed Frog

Self-organization of and by the cytoskeleton is central to the biology of the cell. Since their introduction in the early 1980s, cytoplasmic extracts derived from the eggs of the African clawed-frog, Xenopus laevis, have flourished as a major experimental system to study the various facets of cytoskeleton-dependent self-organization. Over the years, the many investigations that have used these extracts uniquely benefited from their simplified cell cycle, large experimental volumes, biochemical tractability and cell-free nature. Here, we review the contributions of egg extracts to our understanding of the cytoplasmic aspects of self-organization by the microtubule and the actomyosin cytoskeletons as well as the importance of cytoskeletal filaments in organizing nuclear structure and function.

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Neuronal growth and target recognition: lessons from the leech

Canadian Journal of Zoology ◽

10.1139/z00-198 ◽

2001 ◽

Vol 79 (2) ◽

pp. 204-217 ◽

Cited By ~ 2

Author(s):

Michael W Baker ◽

Eduardo R Macagno

Keyword(s):

Nervous System ◽

Target Recognition ◽

Structure And Function ◽

Neuronal Structure ◽

Peripheral Neurons ◽

Unique System ◽

Molecular Studies ◽

The Subject ◽

The 1960S ◽

And Function

The nervous system of the leech has been the subject of numerous studies since its "rediscovery" in the 1960s as a unique system for the study of the properties of glial cells. Subsequently, anatomical, physiological, and embryological studies of identified neurons have yielded a wealth of information about the differentiation of neuronal structure and function. In recent years, cellular approaches to the development of identified central and peripheral neurons have been complemented by molecular studies that promise to reveal the mechanisms by which neurons form their complex arbors and innervate specific targets.

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