scholarly journals Assessment of Physician's Knowledge of Potential Drug-Drug Interactions: An Online Survey in China

2021 ◽  
Vol 8 ◽  
Author(s):  
Jing Yuan ◽  
Chunying Shen ◽  
Chengnan Wang ◽  
Gang Shen ◽  
Bing Han

Background: Drug interactions are the most common preventable cause of adverse drug reaction, which may result in drug toxicity or undesired therapeutic effect with harmful outcomes to patients. Given the rising use of combination therapies, the main objectives of this study were to estimate the degree to which physicians can identify potential drug-drug interactions (PDDIs) correctly and to describe the common source of information used by physicians when they need to check PDDIs.Methods: A cross-sectional survey utilizing a self-administered online questionnaire was conducted among physicians in China. Participants were asked to classify 20 drug pairs as “no interaction,” “may be used together with monitoring,” “contraindication,” and “not sure.” We also collected data on the physician's source of information and altitude toward the PDDIs. An ordinary least square regression model was performed to investigate the potential predictors of PDDI knowledge.Results: Eligible questionnaires were obtained from 618 physicians. The respondents classified correctly 6.7 out of 20 drug pairs, or 33.4% of the drug interactions investigated. The number of drug pairs recognized by respondents was ranged from 0 to 16. The percentage of physicians who recognized specific drug pairs ranged from 8.3% for no interactions between conjugated estrogens and raloxifene, to 64.0% for the interaction between dopamine and phenytoin. When the respondents want to check PDDI information, the most commonly used source of information was package inserts (n = 572, 92.6%), followed by the Internet or mobile Apps (n = 424, 68.6%), consultation with clinical pharmacists (n = 384, 62.1%), medical textbooks (n = 374, 60.5%), knowledge base in Chinese (n = 283, 45.8%), and other physicians (n = 366, 59.2%). In the multiple regression analysis, the significant predictors of a higher number of recognized drug pairs were years of practice and altitudes toward PDDIs.Conclusion: In this online survey accessing physician's ability to detect PDDIs, less than half of the drug pairs were recognized, indicating unsatisfactory level of knowledge about the clinically significant drug interactions. Continuing education and accessible electronic database can help physicians detecting PDDIs and improve drug safety.

2021 ◽  
Vol 14 (1) ◽  
pp. 169
Author(s):  
Fatma Lestari ◽  
Abdul Kadir ◽  
Muhammad Idham ◽  
Fahrul Azwar ◽  
Ganis Ramadhany ◽  
...  

People’s behaviors can affect the spread of the COVID-19 virus. Public behaviors, including proper personal hygiene and healthy life practices, the use of appropriate masks, and the application of good disinfectants, have an important role in human health and protection towards prevention and control of COVID-19 spread. This study aims to perform a survey of public behavior and best practices related to COVID-19 prevention and control among Indonesian communities. A cross-sectional study was designed to collect information using an online survey. Respondents were gathered from 34 provinces in Indonesia through the Indonesia National Safety and Health Council network and Universities network. Respondents voluntarily submitted their response to a predesigned online questionnaire. The collected data was then analyzed using SPSS 24.0. A total of 771 respondent subjects (male 386; female 385) were recruited. The results show that 96% of participants implement positive behavior of personal hygiene, including wearing a mask when going outside their house, and almost 67.3% of respondents sprayed a disinfectant in their house. The majority of participants hold a door handle (37.2%) and desk (28.1%) at a frequency of more than six times a day. There were 8.2% of participants implementing good personal hygiene, including hand-washing at least once a day and maximum of more than six times after going to the toilet. At-risk behaviors were conducted by respondents in which they touched part of their face at a frequency of once during an hour. It was identified that males are less likely to perform better hand hygiene as opposed to females. In conclusion, the study showed that positive behavior of personal hygiene related to COVID-19 has been implemented among Indonesian communities. This result suggests that positive behavior based on community-based prevention and control needs to be continually maintained in order to prevent and control COVID-19 spread.


2021 ◽  
Vol 15 (1) ◽  
pp. 82-85
Author(s):  
Nadia Saleem ◽  

Background: The lockdown strategy has been implemented globally to contain the spread of current pandemic of COVID-19. Educational institutes around the globe are facing challenges and online learning is being carried out to avoid face to face contact during lockdown. Students have to adapt entirely new methods of learning through information technology. Objective: To assess the satisfaction level of health science students with online learning and use of internet during Covid-19 lock down in Punjab. Study Design: Cross-sectional survey. Settings: The data was collected from different institutes of Punjab using an online survey. Duration: Three months from May 2020 to July 2020. Methodology: A convenient sample of sample (N) 357 undergraduate medical students were included based on the response submitted through online questionnaire. Volunteer undergraduate students of MBBS, BDS, DPT, and Pharm D were included. The level of satisfaction was measure using Online Learning/Distance Education Questionnaire. Data was evaluated by SPSS version 22. Frequency tables and percentages was used to measure categorical variables. Results: 41 were males and 316 Females with mean age of 20.5±8.5. 15.6% Most of them had taken more than 03 courses online on computer for educational purpose. More than half students responded that they were motivated to attend online lectures. 23.52 % thought that they can pass any course is on internet-based study. 27.45% considered online and in physical classes as same. The access of internet was not issue for 50.98% students and 37.53% think that course can be completed online. Conclusion: The students were satisfied from online education during this time of transition of conventional classes to online classes. More than half of them felt no issue of internet and 37% think that course can be completed in this mode of education.


Author(s):  
P.O. Olapegba ◽  
O. Ayandele ◽  
S.O. Kolawole ◽  
R. Oguntayo ◽  
J.C. Gandi ◽  
...  

AbstractThis study assessed knowledge and perceptions about COVID-19 among the general public in Nigeria during the initial week of the pandemic lockdown in the country. From March 28 to April 4, 2020, this cross-sectional survey used an anonymous online questionnaire to collect data from respondents within Nigeria. Purposive and snowball sampling techniques were used to recruit 1357 respondents, aged 15-70 years, from 180 cities and towns within Nigeria. Study data were analysed using descriptive statistics. Approximately more than half (57.02%) of the respondents were male with high level of education (48.86% bachelor’s degree or higher). Approximately half of the respondents (46.94%) opined that COVID-19 was “a biological weapon designed by the Chinese government.” About 94% of the respondents identified “contact with airborne droplets via breathing, sneezing, or coughing” as the most common mode of transmission; most respondents associated COVID-19 with coughing (81.13%), shortness of breath (73.47%) and fever (62.79%). “Regular hand washing and social distancing” was selected by most respondents (94.25%) as a way of preventing infection whereas 11.86% reported “consuming gins, garlic, ginger, herbal mixtures and African foods/soups” as preventive measures against COVID-19. Majority of the respondents (91.73%) thought COVID-19 is deadly; and most respondents (84.3%) got 4 or more answers correctly. It was also observed that the traditional media (TV/Radio) are the most common source of health information about COVID-19 (93.5%). Findings revealed that Nigerians have relatively high knowledge, mostly derived from traditional media, about COVID-19. Their perceptions of COVID-19 bear implications across public health initiatives, compliance with precautionary behavior as well as bilateral relations with foreign nations. Evidence-based campaign should be intensified to remove misconceptions and promote precautionary measures.


2021 ◽  
Vol 108 (Supplement_7) ◽  
Author(s):  
Maitreyi Patel ◽  
Naveed Kirmani

Abstract Aims We aim to assess the surgeons’ awareness of mesh characteristics by way of an online survey. Methods A cross sectional survey of surgeons routinely performing groin hernia repairs was conducted across five NHS hospitals using an online questionnaire. Surgeon’s experience in groin hernia repair was taken in account. The data was analyzed using Microsoft Excel. Descriptive statistics was used. Results 37 surgeons responded to the survey.6 surgeons had more than 20 years of experience. 8 (21.62%) performed >50 hernia repairs annually. When compared with years of experience, knowledge of material was 100% with >10 years experience. Knowledge of tensile strength was 50% in those with > 20 years experience, while 83% of respondents with >20 years experience were aware of the weight and pore size of the mesh they used. In comparison with the number of groin hernia repairs done annually, all respondents performing >50 repairs knew the material they used. Amongst these respondents, knowledge of tensile strength, weight and pore size was 38%, 75% and 63% respectively. Conclusions Our study suggests that the level of knowledge regarding mesh is inadequate among surgeons, falling short of the minimum expected of surgeons performing groin hernia repair.


2008 ◽  
Vol 32 (11) ◽  
pp. 417-418 ◽  
Author(s):  
Akshya Vasudev ◽  
Richard Harrison

Aims and MethodA cross-sectional survey of patient drug prescriptions on two elderly psychiatric wards was carried out to estimate the potential of drug–drug interactions. Two standardised databases, British National Formulary (BNF; British Medical Association & Royal Pharmaceutical Society of Great Britain, 2007) and Upto Date (www.uptodate.com/), were employed.ResultsA majority (96%) of drug prescriptions in our study could potentially cause drug–drug interactions. Most patients were on multiple drugs (on average eight drugs per patient). There was poor concordance between the two databases: BNF picked up fewer cases of potential drug–drug interactions than Upto Date (43 v. 152 instances) and they also estimated the potential for hazardousness differently.Clinical ImplicationsPolypharmacy is common in elderly psychiatric patients and this increases the possibility of a drug–drug interaction. Estimating the risk of interactions depends on a sound knowledge in therapeutics and/or referring to a standardised source of information. the results of this study question the concordance of two well-referenced databases.


2021 ◽  
Author(s):  
Fatma Lestari ◽  
Abdul Kadir ◽  
Muhammad Idham ◽  
Fahrul Azwar ◽  
Ganis Ramadhany ◽  
...  

Abstract Background: The trend of COVID-19 confirmed cases has continually risen in Indonesia, this pandemic situation has affected several life sectors, including health sectors, education, economic, services, and employment sectors. Public health and social measures as recommended by Word Health Organization are required to be implemented in order to prevent the coronavirus disease spread. People’s behaviours can also affect the spread of the COVID-19 virus. Public behaviours including proper personal hygiene and healthy life practices, the use of appropriate masks, and the application of good disinfectants have an important role in human’s health and protection towards prevention and control of COVID-19 spreads. This study aims to perform a survey of public behaviour and best practices related to COVID-19 prevention and control among Indonesian communities. Methods: A cross-sectional study was designed to collect information related to public behaviour related to COVID-19 prevention and control using an online survey. Respondents were gathered from 34 provinces in Indonesia through the Indonesia National Safety and Health Council network and Universities network. Respondents voluntarily submitted their response to a pre-designed online questionnaire. The collected data was then analyzed using SPSS 24.0. Results: A total of respondents 771 subjects (male 386; female 385) were submitted their response. The results show that 96% of participants implementing positive behaviour of personal hygiene including wearing a mask when going outside their house and almost 67.3% of respondents sprayed a disinfectant in their house. The majority of participants hold a door handle (37.2%) and desk (28.1%) at frequency of more than six times a day. There were 8.2% of participants implementing good personal hygiene including hand washing at least once a day and maximum of more than six times after going to the toilet. At risk behaviour were conducted by respondents at which they touched part of their face at frequency once during an hour. It has been identified that male are less likely to perform better hand hygiene as opposed to female. In conclusion, study showed that positive behaviour of personal hygiene related to COVID-19 has been implemented among Indonesian communities. This result suggested that positive behaviour based on community based prevention and control need to be continually maintain in order to prevent and control COVID-19 spreads.


Author(s):  
Tshokey Tshokey ◽  
Deepika Adhikari ◽  
Thinley Jamtsho ◽  
Kinley Wangdi

Introduction: Concerns about antibiotic resistances is increasing. Antibiotic misuses mostly result from inadequate knowledge impacting attitudes and practices. The literature on this subject is limited in Bhutan.  It is of immense importance to understand the gap and target interventions. Therefore, we assessed the knowledge, attitudes and practices (KAP) on antibiotics amongst Bhutanese university graduates in 2016. Methods: The survey was conducted through a self-administered online questionnaire after seeking consent. The questionnaire was developed by the investigators using past literature.   Results: Of the 2,229 invited graduates, only 220 (≈10%), 52.3% (115) males, completed the survey. Internet was the commonest source of information on antibiotics. Only 51% (113) showed good knowledge with a mean score of 15.5 (range 2-30). Penicillin, amoxicillin and cotrimoxazole were correctly identified as antibiotics by 63.6%, 78.7% and 21.4% but 11.4%, 35% and 31.8% misidentified atenolol, paracetamol and ibuprofen as antibiotics respectively. Side effects of antibiotics were poorly recognized. Fifty-four percent (119) showed good attitude score. About 39% (85), 35% (76) and 46% (101) misconceived that antibiotics would be required for common cold, all fevers and all small clean-cut wounds respectively. Almost 91% knew that antibiotic courses should be completed, 12% thought that antibiotics can be stopped when patients improve and 31.8% repeated antibiotics for similar illnesses. Although 76% knew that antibiotics shouldn’t be bought without a prescription, 28% were able to get them. About 44.1% revealed that the dispensing pharmacists did not explain adequately about antibiotics. Unfortunately, 43.6% suggested others to take antibiotics during illnesses and 60% used topical antibiotics. Conclusion: KAP on antibiotics amongst Bhutanese graduates was unsatisfactory except few good specific practices. Health authorities should educate public on antibiotics and other medicines.


2020 ◽  
Author(s):  
Peter O. Olapegba ◽  
Olusola Ayandele ◽  
Samson Olowo Kolawole ◽  
Rotimi Oguntayo ◽  
Joshua Chiroma Gandi ◽  
...  

This study assessed knowledge and perceptions about COVID-19 among the general public in Nigeria during the initial week of the pandemic lockdown in the country. From March 28 to April 4, 2020, this cross-sectional survey used an anonymous online questionnaire to collect data from respondents within Nigeria. Purposive and snowball sampling techniques were used to recruit 1357 respondents, aged 15-70 years, from 180 cities and towns within Nigeria. Study data were analysed using descriptive statistics. Approximately more than half (57.02%) of the respondents were male with high level of education (48.86% bachelor’s degree or higher). Approximately half of the respondents (46.94%) opined that COVID-19 was “a biological weapon designed by the Chinese government.” About 94% of the respondents identified “contact with airborne droplets via breathing, sneezing, or coughing” as the most common mode of transmission; most respondents associated COVID-19 with coughing (81.13%), shortness of breath (73.47%) and fever (62.79%). “Regular hand washing and social distancing” was selected by most respondents (94.25%) as a way of preventing infection whereas 11.86% reported “consuming gins, garlic, ginger, herbal mixtures and African foods/soups” as preventive measures against COVID-19. Majority of the respondents (91.73%) thought COVID-19 is deadly; and most respondents (84.3%) got 4 or more answers correctly. It was also observed that the traditional media (TV/Radio) are the most common source of health information about COVID-19 (93.5%). Findings revealed that Nigerians have relatively high knowledge, mostly derived from traditional media, about COVID-19. Their perceptions of COVID-19 bear implications across public health initiatives, compliance with precautionary behavior as well as bilateral relations with foreign nations. Evidence-based campaign should be intensified to remove misconceptions and promote precautionary measures.


2021 ◽  
Vol 8 (39) ◽  
pp. 3423-3428
Author(s):  
Khyati Gagan Kalra ◽  
Vaishali Praful Bansod ◽  
Shraddha Shripad Kulkarni ◽  
Parvinder Singh Chawla

BACKGROUND As of 29th June 2021, 182,261,516 total cases of Covid-19 with 3,947,170 deaths have been reported worldwide from 218 countries, out of which 30,316,897 Covid19 cases and 397,668 deaths are from India.1 Maharashtra contributing 19,16,236 cases and 49,189 deaths.2 Hands are one of the main pathways of transmission of the virus. All out efforts have been made by the Governments and health agencies to increase awareness on hand hygiene among general population. However, it is felt that compliance of general population to hand hygiene is poor. So, this study was carried out to assess the knowledge, attitude and practices (KAP) of hand hygiene to prevent the spread of corona virus, among general population during pandemic. METHODS A cross sectional study was carried out among general population aged 15 years and above through an online survey obtaining the data by a predesigned google form and analysed using Epi Info V7. RESULTS 513 individuals from 17 states of India responded. Participation was almost equal in both genders (47.6 % male and 52.4 % females). Majority of the participants (65 %) had good knowledge regarding modes of transmission. In this study, online platforms and doctors emerged to be the most common source of Covid related information. 79.14 % participants had knowledge regarding hand hygiene as an important method of prevention of Covid infection. But only 14.8 % knew the exact time to be devoted towards hand hygiene. Majority had favourable attitude and practices towards hand hygiene. 80.15 % participants from urban area told that 20 - 30 seconds as minimum time for alcohol-based sanitizer to kill most germs on hands which was found statistically significant. CONCLUSIONS Majority of participants had good knowledge, favourable attitude and practices regarding hand hygiene as a mode of prevention for Covid-19 infection during this ongoing pandemic situation. Still continuous and more detailed demonstrations of hand washing as well as time to be devoted to hand washing and use of sanitizer is required to break chain of transmission and contain Covid-19 disease. KEYWORDS Covid-19, Hand Washing, Hand Rub


2020 ◽  
Author(s):  
Harry Barton Essel ◽  
Akosua Tachie-Menson ◽  
Mavis Osei ◽  
Emmanuel Yeboah

Abstract Background: Ghana’s COVID-19 caseloads stretched to 32,437 with 161 deaths. After the first COVID-19 case recorded in March, the Government of Ghana imposed several restrictions on the life of citizenry to prevent the spread of the infection. However, it is imperative to assess and track the knowledge, misperceptions, attitudes and behaviour of Ghanaian on this public health emergency that is moving fast and not well understood before lives are restored to normalcy. This study investigated the knowledge, misperceptions, attitudes and behaviour of Ghanaians on the COVID-19 pandemic through a rapid online survey system.Methods: The Cochran sample size determination formula was used to estimate a representative sample of adult Ghanaian residents (n = 420) for the cross-sectional survey. An online questionnaire (eQuestionnaire) designed with Google Form was administered to the participants who consented to be part of this study. SMS and popular social media handles were used for the distribution of the eQuestionnaire URL to the participants. The survey commenced on July 5th 2020 through to July 15th,2020. Socio-demographic data of participants were gathered on age, gender, religion and level of education. Data collected were analysed using summary and inferential statistics. Results: A total of 475 adult Ghanaian participants completed the eQuestionnaire. Some Ghanaians believed that the COVID-19 pandemic is a myth (95% CI 25.6%-48.1%) and it does not have any effect on a Ghanaian (African) because of the hot temperate we experience. Majority of the participants (78.2%) thought that older adults were at high risk of death when disease-ridden with COVID-19 pandemic. The majority of the participants (81.5%) were poise that Ghana can successfully manage the COVID-19 pandemic. About 31.5% of the participants indicated they did not wear facial or nose masks when going out of their homes. The participants (81.9%, 389/475) approved that the government should ease the COVID-19 restrictions for life to return normalcy.Conclusion: Although Ghanaians have appreciable knowledge, positive attitude and appropriate behaviour in response to COVID-19 pandemic, a well-coordinated effort is needed to ensure stringent compliance with healthcare protocols toward the easing of COVID-19 restrictions in Ghana.


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