scholarly journals Metabolic Risk Factors Associated With Chronic Kidney Disease in a Middle-Aged and Elderly Taiwanese Population: A Cross-Sectional Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Mei-Chun Lu ◽  
I-Ju Chen ◽  
Le-Tien Hsu ◽  
Ying-Jen Chen ◽  
Meng-Ting Tsou ◽  
...  
Keyword(s):  
Risk Factors ◽  
Chronic Kidney Disease ◽  
Elderly Population ◽  
Cross Sectional Study ◽  
Metabolic Risk ◽  
Multiple Logistic Regression ◽  
Sectional Study ◽  
Middle Aged ◽  
Cross Sectional ◽  
Factors Associated

Background: This study aimed to quantify the proportion of participants with chronic kidney disease (CKD) and associated metabolic risk factors in a middle-aged and elderly population in Guishan District, Taoyuan City, Taiwan.Methods: This cross-sectional study enrolled residents aged 50–90 years living in one community. All participants received a standardized personal interview, including a structured questionnaire, anthropometric measurements, and blood samples collected for laboratory testing. CKD was defined as the presence of kidney damage (urine albumin-creatinine ratio ≥30 mg/g) or estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2. Multiple logistic regression models were used to evaluate the risk factors associated with CKD.Results: A total of 400 participants were enrolled. The overall proportion of participants with CKD was 20.5% (95% confidence interval [CI]: 16.54–24.46%). The proportions of participants with CKD among those aged 50–64, 65–74, and 75 years and over were 17.7, 18.8, and 35.7%, respectively (p = 0.01). Multiple logistic regression model revealed that elevated blood pressure (odds ratio [OR] = 2.23, 95% CI: 1.16–4.30), hyperglycemia (OR = 2.87, 95% CI: 1.64–5.00), hyperuricemia (OR = 1.38, 95% CI: 1.14–1.69), and metabolic syndrome (OR = 2.30, 95% CI: 1.31–4.06) were significantly associated with CKD.Conclusions: The prevalence of CKD in the study population was high. Hypertension, hyperglycemia, hyperuricemia, and metabolic syndrome are significantly associated with CKD in a middle-aged and elderly population in Taiwan.

scholarly journals Prevalence of chronic kidney disease and associated metabolic risk factors in a middle-aged and elderly Taiwanese population: a cross-sectional study

2020 ◽  
Author(s):  
Mei-Chun Lu ◽  
I-Ju Chen ◽  
Wei-Chung Yeh ◽  
Hai-Hua Chuang ◽  
Yu-Chung Tsao ◽  
...  
Keyword(s):  
Risk Factors ◽  
Metabolic Syndrome ◽  
Chronic Kidney Disease ◽  
Elderly Population ◽  
Cross Sectional Study ◽  
Metabolic Risk ◽  
Multiple Logistic Regression ◽  
Sectional Study ◽  
Middle Aged ◽  
Cross Sectional

Abstract Background: This study aimed to quantify the prevalence of chronic kidney disease (CKD) and associated metabolic risk factors in a middle-aged and elderly population in Guishan District, Taoyuan City, Taiwan. Methods: This cross-sectional study enrolled residents aged 50-90 years living in one community. All subjects received a standardized personal interview, including a structured questionnaire, anthropometric measurements, and blood samples collected for laboratory testing. CKD was defined as the presence of kidney damage (urine albumin-creatinine ratio ≥30mg/g) or estimated glomerular filtration rate (eGFR) <60 mL/min/1.73m 2 . Multiple logistic regression models were used to evaluate risk factors associated with CKD. Results : A total of 400 subjects were enrolled. The overall prevalence of CKD was 20.3% (95% CI: 16.36–24.24%). The age-specific prevalence of CKD in subjects aged 50-64 years, 65-74 years, and 75 years and over was 17.7%, 18.8%, and 33.9%, respectively, (p value for Cochran-Armitage trend test = 0.022). Multiple logistic regression model revealed that elevated blood pressure (OR = 2.55, 95% CI: 1.30–5.01), hyperglycemia (OR = 2.78, 95% CI: 1.59–4.88), hyperuricemia (OR = 1.36, 95% CI: 1.12–1.65) and metabolic syndrome (OR = 2.48, 95% CI: 1.40–4.40) were statistically and significantly associated with CKD. Conclusions: The prevalence of CKD in our study population is high. Hypertension, hyperglycemia, hyperuricemia and metabolic syndrome are significantly associated with CKD in a middle-aged and elderly population in Taiwan.

scholarly journals A study of non-communicable diseases risk factors among the tribal population of Lefunga block, Tripura: cross sectional study

2018 ◽  
Vol 5 (10) ◽  
pp. 4478
Author(s):  
Aman Kumar ◽  
Rupali Choudhury ◽  
Sushma Yadav
Keyword(s):  
Risk Factors ◽  
Abdominal Obesity ◽  
Communicable Disease ◽  
Cross Sectional Study ◽  
Tribal Population ◽  
Multiple Logistic Regression ◽  
Sectional Study ◽  
Cross Sectional ◽  
Factors Associated ◽  
Non Communicable Disease

Background: The burden of non-communicable diseases such as diabetes and coronary heart disease is increasing both globally and in India. The present study was conducted to estimate the prevalence of risk factors associated with non-communicable disease and to study the association of the risk factors with non-communicable disease among tribal population of Lefunga Block of Tripura.Methods: A cross-sectional study was conducted in Lefunga block during April to June 2017 among 150 Indigenous tribal population of Tripura. Multistage random sampling was used. A predesigned, pretested, semi-structured modified WHO STEPs questionnaire was used. Chi square and Multiple Logistic Regression was done to see association.Results: Mean age was 39.03±12.76 years. Majority (66.7%) were females and (44.7%) had studied up to secondary. (26%) were tobacco smokers and (68%) were tobacco chewing. (36%) were alcoholic. (89.3%) had exercising for <2.5 hrs. 68% were taking vegetables >10 times/ week and 88.7% were taking fruits <5 times/week. (26%) were overweight, (45.3%) had abdominal obesity and 31% were hypertensive. 93.3% were aware of the harmful effects of tobacco consumption. Multiple logistic regression analysis showing factors associated with male were more likely to had higher abdominal obesity and alcohol user >50 yrs, government employee. With smoking, male having more chances of smoking and Age group of 20-30 yrs and 31-40 yrs.Conclusions: The mean age was 39.03±12.76 years. (26%) were overweight, (45.3%) had abdominal obesity and (31%) were hypertensive. NCD clinic, IEC should be increased. 

Cardiovascular and metabolic risk factors in physically active and inactive Portuguese middle-aged adults: A cross-sectional study

2020 ◽  
Vol 35 (4) ◽  
pp. e91-e98
Author(s):  
M.-R.G. Silva ◽  
H.-H. Silva ◽  
S. Capkauskiene ◽  
V. Rosado-Marques ◽  
A.M. Machado-Rodrigues ◽  
...  
Keyword(s):  
Risk Factors ◽  
Cross Sectional Study ◽  
Metabolic Risk Factors ◽  
Metabolic Risk ◽  
Sectional Study ◽  
Middle Aged ◽  
Cross Sectional ◽  
Physically Active ◽  
Middle Aged Adults

scholarly journals A retrospective cross-sectional study for predicting 72-h mortality in patients with serum aspartate aminotransferase levels ≥ 3000 U/L

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kai Saito ◽  
Hitoshi Sugawara ◽  
Tamami Watanabe ◽  
Akira Ishii ◽  
Takahiko Fukuchi
Keyword(s):  
Risk Factors ◽  
Alkaline Phosphatase ◽  
Creatine Kinase ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Sodium Potassium ◽  
Factors Associated ◽  
C Statistic ◽  
Serum Aspartate Aminotransferase

AbstractRisk factors associated with 72-h mortality in patients with extremely high serum aspartate aminotransferase levels (AST; ≥ 3000 U/L) are unknown. This single-centre, retrospective, case-controlled, cross-sectional study obtained data from medical records of adult patients treated at Saitama Medical Center, Japan, from 2005 to 2019. We conducted a multivariate logistic after adjusting for age, sex, height, weight, body mass index, Brinkman Index, vital signs, biochemical values, updated Charlson Comorbidity Index (CCI) score, CCI components, and underlying causes. A logistic regression model with selected validity risks and higher C-statistic for predicting 72-h mortality was established. During the 15-year period, 428 patients (133 non-survivors and 295 survivors [cases and controls by survival < 72 and ≥ 72 h, respectively]) with AST levels ≥ 3000 U/L were identified. The 72-h mortality rate was 133/428 (31.1%). The model used for predicting 72-h mortality through the assessment of alkaline phosphatase, creatine kinase, serum sodium, potassium, and phosphorus levels had a C-statistic value of 0.852 (sensitivity and specificity, 76.6%). The main independent risk factors associated with 72-h mortality among patients with AST levels ≥ 3000 U/L included higher serum values of alkaline phosphatase, creatine kinase, serum sodium, potassium, and phosphorus.

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