scholarly journals Association Between Overweight Sarcopenic Population and Acute Vertebral Osteoporotic Compression Fractures in Females: Retrospective, Cross-Sectional Study

2021 ◽  
Vol 8 ◽  
Author(s):  
Younghun Lee ◽  
Ho-Jae Lee ◽  
Siyeong Yoon ◽  
Jaeyeon Shin ◽  
Kyung-Chae Park ◽  
...  

Background: This study aimed to determine whether the prevalence of acute vertebral osteoporotic compression fractures (VOCF) in the elderly population is related to the distribution of muscles and fat in the human body.Methods: Data of acute VOCF and non-VOCF patients presenting at our institution between January 2018 and May 2020 were analyzed. Patients aged 65 years and older, who underwent body composition test and dual-energy X-ray absorptiometry at the same time were enrolled. After applying exclusion criteria, patients were divided into four groups: normal, sarcopenia without obesity, obesity without sarcopenia, and sarcopenic obesity. Body mass index ≥25 kg/m2 was considered obesity, and sarcopenia was defined as skeletal muscle index lower than 7.0 kg/m2 in males and 5.4 kg/m2 in females. The VOCF rate was analyzed between the groups.Discussion: A total of 461 patients were included, of whom 103 were males. Among them, 163 (35.36%) had normal body composition, 151 (32.75%) had sarcopenia without obesity, 110 (23.86%) had obesity without sarcopenia, and 37 (8.03%) had sarcopenic obesity. The sarcopenic obesity group had the highest rate of acute VOCF (37.8%), which was statistically significant. Specifically, females with sarcopenic obesity and sarcopenia without obesity had significantly higher acute VOCF rates compared to those with normal body compositions. Multivariate analysis showed that sarcopenic obesity was significantly associated with acute VOCF rate overall, as well as in females.Conclusion: Sarcopenic obesity is strongly associated with acute VOCF, especially in females, and it could be an essential criterion for the prevention of acute VOCF.

2020 ◽  
Vol 23 (16) ◽  
pp. 2923-2931 ◽  
Author(s):  
Chika Okada ◽  
Emiko Okada ◽  
Hidemi Takimoto

AbstractObjective:To examine nutrient and food intakes according to the levels of skeletal muscle mass index (SMI) in the elderly.Design:Cross-sectional study.Setting:Data were derived from the 2017 National Health and Nutrition Survey in Japan. SMI was calculated by dividing appendicular skeletal muscle (or lean) mass (kg) by height squared (m2). We calculated the multivariable-adjusted means of individuals’ dietary intake. Dietary intake of energy, nutrients and food categories was assessed by examining dietary records using a semi-weighed method and compared according to the sex-specific quartiles of SMI.Participants:Men and women aged ≥60 years.Results:Among 797 men and 969 women, individuals with a higher SMI consumed more energy and more nutrients than did those with a lower SMI after adjusting for age, lifestyle and physical activity factors. After further adjusting for energy intake, total dietary fibre, vitamin A, vitamin B6, K, Fe and Cu were positively associated with higher SMI in men (Pfor trend < 0·05). For food categories, men with a higher SMI consumed more vegetables and meats, but the associations were attenuated after adjustment for energy and remained significant for vegetable only (Pfor trend = 0·018).Conclusions:Japanese elderly people with a higher SMI consumed more energy and nutrients and more vegetables than did those with a lower SMI. This finding shows that diet is important in preventing muscle loss among the elderly in an ageing society.


2021 ◽  
Author(s):  
Aliyu Tijani Jibril ◽  
Atieh Mirzababaei ◽  
Farideh Shiraseb ◽  
Niloufar Rasaei ◽  
Khadijeh Mirzaei

Abstract Objectives Obesity is a major risk factor for metabolic syndrome, with its prevalence has increased over the past decade. Major changes in body composition with aging have a significant effect on many clinical outcomes. Sarcopenic obesity consists of both the presence of abnormal adipose tissue with a deficit of muscle mass. Results Of the 241 subjects in this study (average age 35.32 years), 176 (73.03%) were classified as MUO phenotype. Based on this study, the prevalence of sarcopenic obesity was 7.88%. We found that high fat-free mass was more strongly and significantly associated with MUO phenotype. Furthermore, we found that individuals with high fat-free mass and high skeletal muscle mass had a significantly low prevalence of MUO phenotype. A significant positive correlation between metabolic phenotypes and sarcopenic obesity was also observed after all potential covariates were adjusted for. These results of this study suggest that increased adiposity and decreased skeletal muscle mass are associated with unfavorable metabolic traits among overweight and obese Iranian women. SO was also found to be associated with a greater risk of developing MUO phenotype.


2020 ◽  
Vol 3 (3) ◽  
pp. 23-28
Author(s):  
Silvana Schwerz Funghetto ◽  
Alessandro Oliveira Silva ◽  
Maurilio Tiradentes Dutra ◽  
Marina Morato Stival ◽  
Yuri Gustavo Sousa Barbalho ◽  
...  

The combination of increased fat mass with a decrease in muscle mass and strength in the elderly has been termed sarcopenic obesity (SO). In addition, augmented levels of inflammatory markers have been reported in subjects with SO. Two hundred-sixteen obese elderly women were included in this cross-sectional study. They underwent body composition analysis by DEXA to define the presence of SO. Volunteers were divided into two groups: SO (n= 83; 66.7 ± 5.6 years) and non-SO (n= 133; 67.6 ± 4.9 years) for the comparison of inflammatory cytokines.  There were no significant differences between SO and non-SO groups in the blood concentrations of the inflammatory markers analyzed, e.g. interleukin-6 (0.82 ± 0.20 vs 0.83 ± 0.19 pg/ml; p=0.64), C-reactive protein (2.70 ± 1.55 vs 2.82 ± 1.66 pg/ml; p=0.71), tumor necrosis factor alpha (0.71 ± 0.08 vs 0.70 ± 0.08 pg/ml; p=0.42) and interferon-gamma (0.75 ± 0.14 vs 0.74 ± 0.08 pg/ml; p=0.47), respectively. Thus, in the studied population, inflammatory markers are not exacerbated by SO when compared to obesity without sarcopenia.


BMJ Open ◽  
2019 ◽  
Vol 9 (6) ◽  
pp. e025477 ◽  
Author(s):  
Jaesung Choi ◽  
Ji-Yeob Choi ◽  
Sang-Ah Lee ◽  
Kyoung-Mu Lee ◽  
Aesun Shin ◽  
...  

ObjectivesThis study evaluated whether individuals with affected family member adhered to healthy behaviours.Design and settingThis was a cross-sectional study of participants selected from health examinees who underwent the national health check-up programme of Korea in 39 centres between 2004 and 2013.ParticipantsThe baseline data of 128 520 participants enrolled in the Health Examinees-Gem study were used for analysis.Main outcomes and measuresAssociations of family history of diabetes with adherence to regular exercise, healthy diet and body composition, and clusters of healthy behaviours were evaluated while adjusting for potential confounders selected by a directed acyclic graph.ResultsParticipants with a family history of diabetes were more likely to adhere to a regular exercise regimen (OR=1.12, 95% CI 1.06 to 1.18 for men and OR=1.10, 95% CI 1.07 to 1.14 for women) and healthy diet (OR=1.06, 95% CI 1.01 to 1.12 for men and OR=1.06, 95% CI 1.01 to 1.12 for women) but were less likely to have a normal body composition (OR=0.83, 95% CI 0.78 to 0.87 for men and OR=0.83, 95% CI 0.80 to 0.86 for women). These associations were strengthened when the affected family members were siblings, the number of affected members was increased or the age at diagnosis of the affected member was younger than 50 years. In men and women, having a normal body composition is important in determining the cluster of behaviours, and those with a family history of diabetes were less likely to adhere to the normal body composition cluster.ConclusionsThe group with high risk of diabetes showed healthy behaviors, but they did not have a normal body composition. Policies and campaigns targeting integrated health behaviors will be needed to reduce the burden of diseases and improve public health.


2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Yanping Du ◽  
Xiaodong Wang ◽  
Hua Xie ◽  
Songbai Zheng ◽  
Xiaoqing Wu ◽  
...  

Abstract Background Sarcopenia and sarcopenic obesity (SO) have a greater impact on the elderly. This study aimed to explore whether there were sex differences in the prevalence and adverse outcomes of sarcopenia and SO in community-dwelling elderly individuals in East China. Methods This was a cross-sectional study that enrolled 213 males and 418 females aged > 65 years. Demographic characteristics, body composition, hand grip, gait speed, and indices of glucose and lipid metabolism were collected. Sarcopenia and SO were diagnosed using the Asian Working Group for Sarcopenia criteria. Results (1) The prevalence of sarcopenia was 19.2% in males and 8.6% in females. The prevalence of SO was 7.0% in males and 2.4% in females. (2) In males, the odds ratios (ORs) of osteoporosis and dyslipidemia in the SO group were 4.21-fold and 4.15-fold higher than those in the normal group, respectively. In females, the ORs of osteoporosis and hyperglycemia in the SO group were 1.12-fold and 4.21-fold higher than those in the normal group. Conclusions Males were more likely to be sarcopenic and to have SO than females using the AWGS criteria. Females with SO were more likely to have higher blood glucose, whereas males with SO were more likely to have osteoporosis and dyslipidemia.


Nutrients ◽  
2021 ◽  
Vol 13 (8) ◽  
pp. 2744
Author(s):  
Yanfei Wang ◽  
Xiaoyan Chen ◽  
Yunyi Wang ◽  
Ziqi Liu ◽  
Yu Fang ◽  
...  

Background and aims: Muscle mass reduction (MMR) is one of the three etiologic criteria in the Global Leadership Initiative on Malnutrition (GLIM) framework. This study aimed to evaluate the value of MMR in GLIM criteria among ambulatory cancer patients. Methods: A single-center prospective cross-sectional study was conducted. All participants underwent calf circumference (CC) measurement and body composition measurement by bioelectrical impedance analysis (BIA). MMR was identified by CC, fat-free mass index (FFMI), appendicular skeletal muscle index (ASMI), or combinations of the above three indicators. Patients-generated Subjective Global Assessment (PG-SGA) was used as the comparator. Results: A total of 562 cancer patients receiving intravenous treatment were evaluated. Of the participants, 62.8% (355/562) were male. The median age of the patients was 59.0 years (range, 21–82 y). The median BMI was 22.8 kg/m2 (range, 14.6–34.5 kg/m2). A total of 41.8% of patients were evaluated as malnutrition (PG-SGA ≥ 4), and 11.9% were diagnosed with severe malnutrition (PG-SGA ≥ 9). For the GLIM criteria, the prevalence of malnutrition was 26.9%, and severe malnutrition was 12.3%. For all criteria combinations of GLIM together versus PG-SGA, sensitivity was 60.4% (53.8–66.7), specificity was 97.9% (95.4–99.1), while the accordance between GLIM and PG-SGA was moderate (κ = 0.614). The performance of the GLIM worsened when MMR was excluded (κ = 0.515), with reduced sensitivity (50.2% (43.7–56.8)) and the same specificity (97.9% (95.4–99.1)). Including FFMI and ASMI by BIA can further improve the performance of GLIM than using CC alone (κ = 0.614 vs. κ = 0.565). Conclusions: It is important to include MMR in the GLIM framework. Using body composition measurement further improves the performance of the GLIM criteria than using anthropometric measurement alone.


2020 ◽  
Author(s):  
Aliyu Tijani Jibril ◽  
Atieh Mirzababaei ◽  
Farideh Shiraseb ◽  
Niloufar Rasaei ◽  
Khadijeh - Mirzaei

Abstract Background Obesity is a major risk factor for metabolic syndrome, with its prevalence has increased over the past decade. Major changes in body composition with aging have a significant effect on many clinical outcomes. Sarcopenic obesity consists of both the presence of abnormal adipose tissue with a deficit of muscle mass. Methods This cross-sectional study was conducted among a total of 241 overweight/obese women aged between 18–48 years in Tehran, Iran, registered by the use of the multistage cluster random sampling method. Blood samples were taken following standard procedures. Body composition was assessed through a multi-frequency bioelectrical impedance analyzer. The metabolic risk was assessed according to Karelis criteria and the subjects were classified as either MHO or MUO phenotypes. Results Of the 241 subjects in this study (average age 35.32 years), 176 (73.03%) were classified as MUO phenotype. Based on this study, the prevalence of sarcopenic obesity was 7.88%. We found that high fat-free mass was more strongly and significantly associated with MUO phenotype. Furthermore, we found that individuals with high fat-free mass and high skeletal muscle mass had a significantly low prevalence of MUO phenotype. A significant positive correlation between metabolic phenotypes and sarcopenic obesity was also observed after all potential covariates were adjusted for. Conclusion These results of this study suggest that increased adiposity and decreased skeletal muscle mass are associated with unfavorable metabolic traits among overweight and obese Iranian women. SO was also found to be associated with a greater risk of developing MUO phenotype.


2020 ◽  
Vol 44 (2) ◽  
pp. 73-80
Author(s):  
Kaustav Das ◽  
Subrata Bagchi ◽  
Somosree Pal ◽  
Sayak Ganguli ◽  
Koel Mukherjee

Undernutrition and ageing may have a significant effect on body composition. A cross sectional study was conducted to explore the age-related variations among different anthropometric and body composition characteristics amongst the adult Kheria Sabar males of Purulia district of West Bengal. From fifteen villages, 304 apparently healthy adult males aged 18–60 years were selected at random. Subjects were categorized into four age groups and standard anthropometric measurements were used like height (HT), weight (WT), mid-upper-arm circumference (MUAC) and skinfolds of biceps (BSF), triceps (TSF) and sub-scapular (SSSF) region. Derived variables of body mass index (BMI), per cent body fat (PBF), fat mass (FM), fat-free mass (FFM), fat mass index (FMI) and fat-free mass index (FFMI) were also calculated. Majority of the variables were found to be inversely correlated with age. Positive (HT, WT, MUAC, BMI, FFM and FFMI) and negative (FM and FMI) significant differences were observed across different age groups. It was also observed that the frequency of undernutrition (62.6%) was the highest among the elderly people with 47.6% overall prevalence. This study clearly indicates that among the undernourished individuals, older people were more vulnerable to malnutrition and thus immediate nutritional intervention is required.


2011 ◽  
Vol 4 (5) ◽  
pp. 509-511
Author(s):  
Pranay Gandhi ◽  
◽  
Sunita Sharma ◽  
Prateek Gandhi

2019 ◽  
pp. 55-62
Author(s):  
Vuong Diem Khanh Doan ◽  
Ngoc Minh Chau Ho ◽  
Thi Van Ngo ◽  
Thi Bao Nga Phan ◽  
Thi Hong Phan Nguyen

Background: Vietnam is entering the stage of aging population; as a result, the quality of life (QOL) of the elderly is really a matter of concern. There is a great deal of research on the quality of life of the elderly while Vietnam witnesses a lack of research on this topic, especially on how physical and social activities have impact on QOL of the elderly. Objectives: (1) To describe the situation of participation in physical, social activities and QOL of the elderly residing in Truong An Ward, Hue city. (2) To examine the association between physical, social activities and QOL among participants. Methodology: This study used cross-sectional study design. A total sample of 420 people aged 60 and above in Truong An Ward, Hue city were interviewd. The SF36 was used to measure the QOL of participants. Results: Percentage of the elderly taking part in physical activity were 66%. 49% reported having the habit of taking part in social activities. The majority of the elderly get their QOL level in three health fields, namely physical, mental and general health at above average. (56.0, 60.7 and 60.8 respectively). There were significant associations between physical activities, social activities and QOL among participants. Conclusion: The percentage of the elderly taking part in physical and social activities were still low. Besides, QOL of the elderly at the research location was not really high. It’s important to encourage the elderly taking part in physical and social activities to improve their quality of life. Key words: Physical activities, social activities, QOL, the elderly


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