scholarly journals Novel Non-invasive Strategy for Spinal Neuromodulation to Control Human Locomotion

2021 ◽  
Vol 14 ◽  
Author(s):  
Tatiana Moshonkina ◽  
Alexander Grishin ◽  
Irina Bogacheva ◽  
Ruslan Gorodnichev ◽  
Alexander Ovechkin ◽  
...  
Keyword(s):  
Human Locomotion ◽  
Invasive Strategy ◽  
Non Invasive

scholarly journals Liposome Photosensitizer Formulations for Effective Cancer Photodynamic Therapy

Pharmaceutics ◽  
2021 ◽  
Vol 13 (9) ◽  
pp. 1345
Author(s):  
Sherif Ashraf Fahmy ◽  
Hassan Mohamed El-Said Azzazy ◽  
Jens Schaefer
Keyword(s):  
Reactive Oxygen Species ◽  
Photodynamic Therapy ◽  
Adverse Effects ◽  
Cellular Uptake ◽  
Treatment Effectiveness ◽  
State Of The Art ◽  
Oxygen Species ◽  
Chemotherapeutic Drugs ◽  
Invasive Strategy ◽  
Non Invasive

Photodynamic therapy (PDT) is a promising non-invasive strategy in the fight against that which circumvents the systemic toxic effects of chemotherapeutics. It relies on photosensitizers (PSs), which are photoactivated by light irradiation and interaction with molecular oxygen. This generates highly reactive oxygen species (such as 1O2, H2O2, O2, ·OH), which kill cancer cells by necrosis or apoptosis. Despite the promising effects of PDT in cancer treatment, it still suffers from several shortcomings, such as poor biodistribution of hydrophobic PSs, low cellular uptake, and low efficacy in treating bulky or deep tumors. Hence, various nanoplatforms have been developed to increase PDT treatment effectiveness and minimize off-target adverse effects. Liposomes showed great potential in accommodating different PSs, chemotherapeutic drugs, and other therapeutically active molecules. Here, we review the state-of-the-art in encapsulating PSs alone or combined with other chemotherapeutic drugs into liposomes for effective tumor PDT.

scholarly journals IMST-55. LYMPH NODE AND URINE METABOLOMICS: A NON-INVASIVE STRATEGY TO PREDICT EFFICACY OF DENDRITIC CELL VACCINE IMMUNOTHERAPY

2016 ◽  
Vol 18 (suppl_6) ◽  
pp. vi99-vi99
Author(s):  
Hassan Azari ◽  
Farhad Dastmalchi ◽  
James R Rocca ◽  
Huadong Zeng ◽  
Aida Karachi ◽  
...  
Keyword(s):  
Lymph Node ◽  
Dendritic Cell ◽  
Dendritic Cell Vaccine ◽  
Cell Vaccine ◽  
Invasive Strategy ◽  
Non Invasive ◽  
Urine Metabolomics

Mo1889 Serum Exosomal MicroRNA Expression Can Be a Novel Non-Invasive Strategy for the Screening of Barrett's Esophagus

2013 ◽  
Vol 144 (5) ◽  
pp. S-684 ◽  
Author(s):  
Ajay Bansal ◽  
Xiaoman Hong ◽  
In-hee Lee ◽  
John House ◽  
Sharad C. Mathur ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Microrna Expression ◽  
Invasive Strategy ◽  
Non Invasive ◽  
Exosomal Microrna

scholarly journals CRT-69 Non Invasive Evaluation Of Cocaine Induced Chest Pain Reduces Cost Compared To Invasive Strategy

2013 ◽  
Vol 6 (2) ◽  
pp. S22-S23
Author(s):  
Saurabh Rajpal ◽  
Andres Vargas ◽  
Ashish Dwary ◽  
Anderson Penuela ◽  
Shivang Shah ◽  
...  
Keyword(s):  
Chest Pain ◽  
Invasive Strategy ◽  
Non Invasive ◽  
Invasive Evaluation

scholarly journals An Efficient Non-Invasive Method for Fetal Ecg Extraction from Abdominal Signals

2020 ◽  
Vol 8 (6) ◽  
pp. 3348-3353
Keyword(s):  
Input Signal ◽  
The Body ◽  
Invasive Strategy ◽  
Non Invasive ◽  
Fetal Ecg ◽  
Invasive Method ◽  
Over The Top

The principle target of this paper is to decide the over the top attributes of a baby during pregnancy by examining a fetal ECG waveform. In obtrusive system of FECG estimation, terminals are embedded inside the body this may cause the burst of films, which is perilous to both the fetal's and mother's lives. It is important to go for non-invasive strategy, right now readings are taken from the mid-region of pregnant ladies which is protected procedure for both mother and fetal. The fetal ECG waveform can be separated by smothering maternal ECG sign and clamor defilements present in the ECG input signal. By breaking down the fetal ECG waveform we can decide the irregularity of baby heart by estimating the fetal pulse and contrasting it and maternal pulse .The variation from the norm found in fetal during pregnancy can be valuable to treat the hatchling against heart related illnesses.

Early invasive versus non-invasive assessment in patients with suspected non-ST-elevation acute coronary syndrome

Heart ◽  
2021 ◽  
pp. heartjnl-2020-318778
Author(s):  
Thomas A Kite ◽  
Andrew Ladwiniec ◽  
J Ranjit Arnold ◽  
Gerry P McCann ◽  
Alastair J Moss
Keyword(s):  
Acute Coronary Syndrome ◽  
High Risk ◽  
Invasive Coronary Angiography ◽  
Standard Of Care ◽  
Optimal Timing ◽  
Invasive Strategy ◽  
Coronary Syndrome ◽  
Non Invasive ◽  
St Elevation ◽  
Elevation Acute Coronary Syndrome

Non-ST-elevation acute coronary syndrome (NSTE-ACS) comprises a broad spectrum of disease ranging from unstable angina to myocardial infarction. International guidelines recommend a routine invasive strategy for managing patients with NSTE-ACS at high to very high-risk, supported by evidence of improved composite ischaemic outcomes as compared with a selective invasive strategy. However, accurate diagnosis of NSTE-ACS in the acute setting is challenging due to the spectrum of non-coronary disease that can manifest with similar symptoms. Heterogeneous clinical presentations and limited uptake of risk prediction tools can confound physician decision-making regarding the use and timing of invasive coronary angiography (ICA). Large proportions of patients with suspected NSTE-ACS do not require revascularisation but may unnecessarily undergo ICA with its attendant risks and associated costs. Advances in coronary CT angiography and cardiac MRI have prompted evaluation of whether non-invasive strategies may improve patient selection, or whether tailored approaches are better suited to specific subgroups. Future directions include (1) better understanding of risk stratification as a guide to investigation and therapy in suspected NSTE-ACS, (2) randomised clinical trials of non-invasive imaging versus standard of care approaches prior to ICA and (3) defining the optimal timing of very early ICA in high-risk NSTE-ACS.

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