scholarly journals Association Between Inflammatory Potential of the Diet and Ulcerative Colitis: A Case-Control Study

2021 ◽  
Vol 7 ◽  
Author(s):  
Zeinab Khademi ◽  
Parvane Saneei ◽  
Ammar Hassanzadeh-Keshteli ◽  
Hamed Daghaghzadeh ◽  
Hamid Tavakkoli ◽  
...  
Keyword(s):  
Ulcerative Colitis ◽  
Case Control Study ◽  
Dietary Habits ◽  
Large Population ◽  
Population Based ◽  
Case Control ◽  
Dietary Intakes ◽  
Health And Nutrition ◽  
Study Participants ◽  
Control Study

Background/Aim: Despite the inflammatory nature of inflammatory bowel disease (IBD), limited data are available on the association of inflammatory potential of the diet and risk of ulcerative colitis (UC). We aimed to investigate the association of inflammatory potential of the diet (IPD) score and odds of UC in a case-control study.Methods: Patients with UC were enrolled from Iranian IBD registry, whose disease was confirmed by a gastroenterologist. Controls were selected randomly from the Study of the Epidemiology of Psycho Alimentary Health and Nutrition (SEPAHAN) study, a large population-based study on more than 8,000 apparently healthy individuals. Dietary intakes of 28 food items obtained from a validated dish-based food frequency questionnaire (FFQ), were used to compute IPD score.Results: This case-control study was carried out among 109 cases and 218 randomly chosen controls. Mean age of cases and controls was 39.5 ± 10.0 and 41.5 ± 11.8 y, respectively. Totally, 52% of study participants were female and 48% were male. After controlling for age, sex, and body mass index (BMI), we found that the patients with UC were more likely to be in the highest quartile of IPD score compared with controls (OR: 2.83; 95% CI: 1.41–5.69, P-trend < 0.001). This association strengthened after additional adjustment for education, smoking, medical history, and physical activity (OR: 3.48; 95% CI: 1.32–9.10, P-trend = 0.003). When we took dietary habits into account, the association was slightly attenuated (OR: 3.33; 95% CI: 1.20–9.20, P-trend = 0.005).Conclusions: We found that adherence to a pro-inflammatory diet was positively associated with greater odds of UC. Further studies are required to confirm these findings.

Dietary inflammatory index and risk of multiple sclerosis: Findings from a large population-based incident case–control study

2020 ◽  
Vol 39 (11) ◽  
pp. 3402-3407 ◽  
Author(s):  
Ibrahim Abdollahpour ◽  
Dejan Jakimovski ◽  
Nitin Shivappa ◽  
James R. Hébert ◽  
Farhad Vahid ◽  
...  
Keyword(s):  
Multiple Sclerosis ◽  
Case Control Study ◽  
Large Population ◽  
Population Based ◽  
Case Control ◽  
Dietary Inflammatory Index ◽  
Incident Case ◽  
Inflammatory Index ◽  
Control Study

Critical appraisal of a large population-based case–control study

2017 ◽  
Author(s):  
Mark Elwood
Keyword(s):  
Dose Response ◽  
Case Control Study ◽  
Large Population ◽  
Quantitative Relationship ◽  
Population Based ◽  
Case Control ◽  
Critical Assessment ◽  
Response Consistency ◽  
The Impact ◽  
Control Study

This chapter shows a large population-based case-control study, to address the quantitative relationship between alcohol consumption and breast cancer. It shows the logistic and design issues, and the assessment of dose-response, consistency and specificity. The critical assessment follows the scheme set out in chapter 10: describing the study, assessing the non-causal explanations of observation bias, confounding, and chance variation; assessing time relationships, strength, dose-response, consistency and specificity, and applying the results to the eligible, source, and target populations; and then comparing the results with evidence from other studies, considering consistency and specificity, biological mechanisms, and coherence with the distribution of exposures and outcomes. The chapter gives a summary and table of the critical assessment and its conclusions; and comments on the impact of the study and research carried out since.

Serum 25-hydroxyvitamin D and risk of breast cancer: results of a large population-based case–control study in Mexican women

2012 ◽  
Vol 23 (7) ◽  
pp. 1149-1162 ◽  
Author(s):  
Veronika Fedirko ◽  
Gabriela Torres-Mejía ◽  
Carolina Ortega-Olvera ◽  
Carine Biessy ◽  
Angelica Angeles-Llerenas ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Case Control Study ◽  
Large Population ◽  
Population Based ◽  
Case Control ◽  
Mexican Women ◽  
Hydroxyvitamin D ◽  
25 Hydroxyvitamin D ◽  
Control Study

Diabetes Mellitus Increases the Risk of Barrettʼs Esophagus: Results from a Large Population Based Case Control Study

2012 ◽  
Vol 107 ◽  
pp. S15-S16 ◽  
Author(s):  
Prasad Iyer ◽  
Herbert Heien ◽  
Bijan Borah ◽  
Gregory Cooper ◽  
Ananya Das ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Case Control Study ◽  
Large Population ◽  
Population Based ◽  
Case Control ◽  
Control Study

scholarly journals Association of Nut Consumption and Lung Cancer Risk in a Large Population‐based Case‐control Study

2015 ◽  
Vol 29 (S1) ◽  
Author(s):  
Jennifer Lee ◽  
Tram Lam ◽  
Dario Consonni ◽  
Agnela Pesatori ◽  
Pier Bertazzi ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Risk ◽  
Case Control Study ◽  
Lung Cancer Risk ◽  
Large Population ◽  
Population Based ◽  
Case Control ◽  
Control Study

scholarly journals Estimating the Risk of Ulcerative Colitis-Associated Pyoderma Gangrenosum: A Population-Based Case-Control Study

2020 ◽  
Author(s):  
Khalaf Kridin ◽  
Giovanni Damiani ◽  
Ralf J Ludwig ◽  
Dana Tzur Bitan ◽  
Arnon D. Cohen
Keyword(s):  
Ulcerative Colitis ◽  
Pyoderma Gangrenosum ◽  
Case Control Study ◽  
Statistical Significance ◽  
Subsequent Development ◽  
Fold Increase ◽  
Population Based ◽  
Case Control ◽  
Control Subjects ◽  
Control Study

Abstract BackgroundUlcerative colitis (UC) is a well-known underlying comorbidity in pyoderma gangrenosum (PG). However, the relative risk conferred by UC for the subsequent development of PG is yet to be explicated.ObjectiveTo estimate the magnitude of the association between UC and the subsequent occurrence of PG, thus enabling to assess the PG risk with UC.MethodsA population-based case-control study was conducted comparing PG patients (n = 302) with age-, sex- and ethnicity-matched control subjects (n = 1,497) regarding the presence of UC. Logistic regression models were utilized for univariate and multivariate analyses.ResultsThe prevalence of UC was greater in patients with PG than in control subjects (7.3% vs. 0.5%, respectively; P < 0.001). A 15-fold increase in the odds of PG with UC (OR, 14.62 95% CI, 6.45–33.18) was observed. This association retained its statistical significance following a sensitivity analysis excluding UC cases diagnosed up to 2 years prior to PG (OR, 9.88; 95% CI, 3.91–24.97), and after adjusting for confounding factors (adjusted OR, 10.78; 95% CI, 4.55–25.52). The median latency between the diagnosis of UC and the development of PG was 4.59 years. Patients with both PG and UC were younger and had a lower prevalence of smoking when compared to the remaining patients with PG.ConclusionsUC increases the odds of developing PG by 15-folds. Physicians managing patients with UC should be aware of this increased burden. Patients with UC may be advised to avoid additional precipitating factors of PG.

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