scholarly journals Maternal-Neonatal Serum Albumin Level and Neonatal Respiratory Distress Syndrome in Late-Preterm Infants

2021 ◽  
Vol 9 ◽  
Author(s):  
Qian Ying ◽  
Xue-qin You ◽  
Fei Luo ◽  
Ji-mei Wang
Keyword(s):  
Serum Albumin ◽  
Preterm Infants ◽  
Distress Syndrome ◽  
Serum Albumin Level ◽  
Placenta Previa ◽  
Albumin Level ◽  
Late Preterm ◽  
Control Group ◽  
Delivery Mode ◽  
Late Preterm Infants

Background: To determine the correlation between maternal-neonatal serum albumin level and respiratory distress syndrome (RDS) in late-preterm infants.Methods: This case-control study included 112 late-preterm newborns admitted to the neonatal intensive care unit of our hospital between January 2018 and July 2019. Those infants were divided into the RDS group (n = 56) and the non-RDS group (n = 56). Levels of maternal-neonatal serum albumin, pregnancy complications, and baseline information of the infants were compared between the two groups.Results: 1. There was no correlation between maternal and neonatal serum albumin measures. The maternal albumin level in the RDS group was lower than that in the control group (33.38 ± 3.31 vs. 33.60 ± 3.31, P > 0.05), but the difference was not statistically significant. The neonatal albumin level in the RDS group was significantly lower than that in the control group (32.70 ± 2.48 vs. 35.66 ± 3.27, P < 0.05). To predict RDS in late-preterm infants, using the albumin cutoff level of 34 g/L provides a sensitivity of 83.9% with a specificity of 62.5%. 2. Gestational age, primipara, placenta previa, antenatal corticosteroid therapy, delivery mode, and neonatal serum albumin level were associated with RDS in the late-preterm infant. 3. After adjustment for gestational age, logistic regression analysis showed that neonatal serum albumin level, placenta previa, and delivery mode were independent risk factors for RDS in late-preterm infants. However, albumin level did not related to the severity of RDS.Conclusion: The decrease in serum albumin within the first day after birth was closely related to the occurrence of RDS in late-preterm infants.

scholarly journals Relationship Between Serum Albumin Levels and Infections in Newborn Late Preterm Infants

2016 ◽  
Vol 22 ◽  
pp. 92-98 ◽  
Author(s):  
Chunyan Yang ◽  
Zhaoguo Liu ◽  
Min Tian ◽  
Ping Xu ◽  
Baoyun Li ◽  
...  
Keyword(s):  
Serum Albumin ◽  
Preterm Infants ◽  
Late Preterm ◽  
Late Preterm Infants

scholarly journals Predictive Value of the Serum Albumin Level on Admission in Patients With Spontaneous Subarachnoid Hemorrhage

2021 ◽  
Vol 8 ◽  
Author(s):  
Feng Shang ◽  
Hao Zhao ◽  
Weitao Cheng ◽  
Meng Qi ◽  
Ning Wang ◽  
...  
Keyword(s):  
Subarachnoid Hemorrhage ◽  
Serum Albumin ◽  
Serum Albumin Level ◽  
Length Of Hospital Stay ◽  
Albumin Level ◽  
Control Group ◽  
Number Of Patients ◽  
Poor Outcomes ◽  
Spontaneous Subarachnoid Hemorrhage

Objective: To determine the effect of the serum albumin level on admission in patients with spontaneous subarachnoid hemorrhage (SAH).Methods: A total of 229 patients with SAH were divided into control and hypoalbuminemia groups. The serum albumin levels were measured. The data, including age, gender, co-existing medical conditions, risk factors, Hunt-Hess (H-H) grade on admission, Glasgow coma score (GCS) on admission, complications during hospitalizations, length of hospital stay, length of intensive care unit (ICU) stay, in-hospital mortality, survival rate, outcome at discharge, and the 6-month follow-up outcome, were compared between the two groups.Results: Older age, an increased number of patients who consumed an excess of alcohol, and a lower GCS on admission were findings in the hypoalbuminemia group compared to the control group (p < 0.001). The ratio of patients with H-H grade I on admission in the hypoalbuminemia group was decreased compared to the control group (p < 0.05). Patients with hypoalbuminemia were more likely to be intubated, and have pneumonia and cerebral vasospasm than patients with a normal albumin level on admission (p < 0.001). Furthermore, the length of hospital and ICU stays were longer in the hypoalbuminemia group than the control group (p < 0.001). Hypoalbuminemia on admission significantly increased poor outcomes at discharge (p < 0.001). The number of patients with severe disability was increased and the recovery rate was decreased with respect to in-hospital outcomes in the hypoalbuminemia group than the control group (p < 0.001).Conclusion: Hypoalbuminemia was shown to be associated with a poor prognosis in patients with SAH.

scholarly journals Effects of a Breastfeeding Support Program on the Prevalence of Exclusive Breastfeeding and Growth in Late Preterm Infants

2020 ◽  
Vol 26 (1) ◽  
pp. 90-97 ◽  
Author(s):  
Gun Ja Jang ◽  
Yeon Ran Hong
Keyword(s):  
Weight Gain ◽  
Preterm Infants ◽  
Exclusive Breastfeeding ◽  
Support Program ◽  
Late Preterm ◽  
Control Group ◽  
Breastfeeding Support ◽  
Late Preterm Infants ◽  
Feeding Type ◽  
Experimental Group

Purpose: The purpose of this study was to investigate the effects of a breastfeeding support program (BSP) on the prevalence of exclusive breastfeeding and growth in late-preterm infants.Methods: A quasi-experimental study was conducted. The participants were 40 late preterm infants (LPIs), of whom 20 were assigned to the experimental group and 20 to the control group. For the mothers in the experimental group, a BSP was provided prior to the LPIs’ discharge and reinforced once a week for 4 weeks. Information on the feeding type was collected by observation and the LPIs’ body weight was measured.Results: There were significant differences in feeding type by group and time. Exclusive breastfeeding was 5.18 times more common in the experimental group than in the control group (odds ratio=5.18, 95% confidence interval=1.11~16.70). However, weekly weight gain did not show a significant relationship with group and time (F=0.40, <i>p</i>=.712).Conclusion: The BSP was helpful for increasing the rate of exclusive breastfeeding in LPIs. Furthermore, the LPIs in the experimental group, which had a higher likelihood of being exclusively breastfed, showed an equivalent amount of weight gain as the LPIs in the control group, in which infants were more likely to be formula-fed.

Study of the clinical significance of serum albumin level in Preeclampsia and in the detection of its severity

2016 ◽  
Vol 4 (1) ◽  
pp. 110-120
Author(s):  
Basima Al Ghazali ◽  
Ahlam Al-Taie
Keyword(s):  
Serum Albumin ◽  
Serum Albumin Level ◽  
Gestational Hypertension ◽  
Albumin Level ◽  
Maternal Serum ◽  
Control Group ◽  
Perinatal Morbidity ◽  
Plasma Albumin ◽  
Mild Preeclampsia ◽  
And Control

Pre-eclampsia is a form of severe disorder of pregnancy, leading to maternal and perinatal morbidity and mortality. Many biochemical markers of preeclampsia have been recognized in maternal serum one of them is serum albumin. The objective of this study is to determine whether plasma albumin level (ALB) is associated with preeclampsia (PE) complications and to evaluate the usefulness of its level as a marker of preeclampsia severity. The studied group were collected in the labour word. First group were normotensive as a control group, the second group with a gestational hypertension, the third group were mild preeclampsia and fourth group had sever preeclampsia. A comparison of the characteristic of each group and the correlation between serum albumin levels and gestational age at time of delivery, pregnancy complications and outcome were statistically analyzed. The results are showed that serum albumin level had statistically significant decline at (P≤0.01) in severe preeclampsia with mean level (2.618-0.328) than in mild preeclampsia (3.155-0.293) in comparison to hypertensive and control group (3.500-0.386), (4.076-1.448) respectively so there is positive correlation between serum albumin levels and severity of disease. We are concluded that serum albumin level in pre-eclampsia can be used as a significant determinant of disease severity and may be used as a useful marker for predicting time of delivery or termination of pregnancy and pregnancy outcomes.

scholarly journals Effects of a breastfeeding coaching program on growth and neonatal jaundice in late preterm infants in South Korea

2021 ◽  
Vol 27 (4) ◽  
pp. 377-384
Author(s):  
Gun Ja Jang ◽  
Sangjin Ko
Keyword(s):  
South Korea ◽  
Preterm Infants ◽  
Head Circumference ◽  
Neonatal Jaundice ◽  
Late Preterm ◽  
Control Group ◽  
Significant Group ◽  
Transcutaneous Bilirubin ◽  
Late Preterm Infants ◽  
Experimental Group

Purpose: This study examined the effects of a breastfeeding coaching program for mothers on growth and neonatal jaundice in late preterm infants (LPIs).Methods: This was a quasi-experimental study (non-randomized intervention) with a time-series design. The study was conducted among 40 LPIs who were admitted to the neonatal intensive care unit of a university hospital in Daegu, South Korea. In the order of admission, the first 21 infants were assigned to the experimental group, and 19 were assigned to the control group. The intervention program consisted of home- based and web-based practical breastfeeding support education for mothers across a total of 5 sessions. Infant growth was measured using body weight, length, and head circumference, and neonatal jaundice was assessed using transcutaneous bilirubin levels.Results: The likelihood of breastfeeding for infants in the experimental group at 4 weeks after discharge was the same as on the day of discharge, whereas it steadily decreased in the control group. There were significant differences in head circumference between the groups. However, weight, length, and transcutaneous bilirubin levels did not show a significant group-time interaction.Conclusion: A formal breastfeeding coaching program should be considered in clinical settings and at home within the first few weeks postpartum.

scholarly journals The Effect of Problem-Solving-Approach-Based Counselling on Maternal Role Adaptation in Women with Late Preterm Infant: A Randomized Controlled Trial

2021 ◽  
Vol 10 (2) ◽  
pp. 62-69
Author(s):  
Atefeh Rajabi ◽  
Azam Maleki ◽  
Mohsen Dadashi ◽  
Farzaneh Karami Tanha
Keyword(s):  
Randomized Controlled Trial ◽  
Problem Solving ◽  
Preterm Infants ◽  
Controlled Trial ◽  
Block Design ◽  
Late Preterm ◽  
Control Group ◽  
Maternal Role ◽  
Late Preterm Infants ◽  
Randomized Controlled

Abstract Introduction: Mothers with preterm infants experience numerous stressful problems which can have negative effects on maternal role adaptation. This study aimed to investigate the effectiveness of consultation using a problem-solving approach on adaptation to the maternal role in women with late preterm infants. Methods: This randomized controlled trial (RCT) was carried out on 80 women with spontaneous late preterm infants recruited at Ayatollah Mousavi Hospital of Zanjan. Using convenience sampling method, the participants were assigned into two groups of intervention and control according to block design. Taking a problem-solving approach, counselling was carried out individually in four sessions. The control group received only routine care. The data were collected using adaptation to maternal role questionnaire including 33 items based on a five-point Likert scale ranging in seven areas, in two steps (before counselling and one month after the last counselling session). Data analysis was performed using the SPSS ver. 16.0 software (SPSS, Inc., Chicago, IL). Results: The total score of adaptations to maternal role and its areas was significantly higher in the intervention group after the follow-up period. Conclusion: A comprehensive counselling including various dimensions of maternity adaptation had a positive effect on improving the adaptation to maternal role in mothers with late preterm infants.

scholarly journals Antenatal dexamethasone use and respiratory distress in late preterm infants: results from first Vietnamese matched cohort study

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Tran Tuan Hung Ho ◽  
Quang Vinh Truong ◽  
Thi Kim Anh Nguyen ◽  
Minh Tam Le ◽  
Vu Quoc Huy Nguyen
Keyword(s):  
Cohort Study ◽  
Treatment Group ◽  
Respiratory Distress ◽  
Preterm Infants ◽  
Matched Control ◽  
Late Preterm ◽  
Control Group ◽  
Matched Control Group ◽  
Late Preterm Infants ◽  
Nicu Admission

Abstract Background Respiratory distress syndrome (RDS) is one of the leading causes of early neonatal morbidity and mortality in late preterm infants (LPIs) worldwide. This matched cohort study aimed to assess how the antenatal dexamethasone use affect the respiratory distress (RD) proportion in preterm newborns between 34 0/7 weeks and 36 6/7 weeks of gestation. Methods This was a prospective cohort study on 78 women with singleton pregnancy who were in threatened preterm birth and had not received prior dexamethasone, who were admitted between 34 0/7 weeks and 36 6/7 weeks at Hue University of Medicine and Pharmacy Hospital from June 2018 to May 2020. The matched control group without dexamethasone use included 78 pregnant women diagnosed with threatened late preterm births who were at similar gestational ages and estimated fetal weights as the treatment group. The treatment group received 6 mg intramuscular dexamethasone every 12 h for a total of 4 doses or until delivery. Primary outcome was the rate of neonatal RD. Secondary neonatal outcomes included the need for respiratory support, neonatal intensive care unit (NICU) admission, hypoglycemia, necrotizing enterocolitis, intraventricular hemorrhage, and neonatal death. Statistical analyses were performed by using SPSS software, version 26.0. Results The proportion of RD in LPI was significantly lower in the treatment group than in the matched control group (10.3% vs. 23.1%, respectively), adjusted Odds Ratio [aOR] 0.29; 95% confidence interval [CI] 0.10 – 0.83 and p = 0.021. Neonatal hypoglycemia was more common in the dexamethasone group than in the matched group (25.6% vs. 12.8%, respectively; aOR, 2.59; 95% CI, 1.06 – 6.33; p = 0.037). There were no significant between-groups differences in the incidence of respiratory support, NICU admission or length of hospital stay. Conclusions Administration of antenatal dexamethasone to women at risk for late preterm birth could help to lower the proportion of respiratory distress in late preterm infants.

scholarly journals Effect of Antenatal Dexamethasone on Respiratory Distress in Late Preterm Infants: Results from the First Vietnamese Matched Cohort Study

2021 ◽  
Author(s):  
Tran Tuan Hung Ho ◽  
Quang Vinh Truong ◽  
Thi Kim Anh Nguyen ◽  
Minh Tam Le ◽  
Vu Quoc Huy Nguyen
Keyword(s):  
Cohort Study ◽  
Treatment Group ◽  
Respiratory Distress ◽  
Preterm Infants ◽  
Matched Control ◽  
Late Preterm ◽  
Control Group ◽  
Matched Control Group ◽  
Late Preterm Infants ◽  
Nicu Admission

Abstract BackgroundRespiratory distress (RD) is one of the leading causes of early neonatal morbidity and mortality in late preterm infants (LPIs) worldwide. This study aimed to evaluate the effect of antenatal dexamethasone on the RD rate in preterm newborns between 34 0/7 weeks and 36 6/7 weeks of gestation.MethodsThis was a prospective cohort study of 78 women with singleton pregnancy who were in threatened preterm birth and had not received prior dexamethasone who were admitted between 34 0/7 weeks and 36 6/7 weeks at Hue University of Medicine and Pharmacy Hospital from June 2018 to May 2020. The matched control group (no dexamethasone) included 78 pregnant women with threatened late preterm births who were at similar gestational ages and estimated fetal weights as the treatment group. The treatment group received 6 mg intramuscular dexamethasone every 12 hours for a total of 4 doses or until delivery. Primary outcome was the rate of neonatal RD. Secondary neonatal outcomes included the need for respiratory support, neonatal intensive care unit (NICU) admission, hypoglycemia, necrotizing enterocolitis, intraventricular hemorrhage, and neonatal death. Statistical analyses were performed by using SPSS software.ResultsThe rate of RD in LPI was significantly lower in the treatment group than in the matched control group (10.3% vs. 23.1%, respectively), with relative risk [RR] 0.44; 95% confidence interval [CI] 0.21 – 0.96 and p = 0.03. Neonatal hypoglycemia was more common in the dexamethasone group than in the matched group (25.6% vs. 12.8%, respectively; RR, 2.00; 95% CI, 1.00 – 3.99; p = 0.04). There were no significant between-group differences in the incidence of respiratory support, NICU admission or length of hospital stay.ConclusionsAdministration of antenatal dexamethasone to women at risk for late preterm birth could significantly reduce the rate of respiratory distress in late preterm infants.

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