scholarly journals Precocious Puberty and Covid-19 Into Perspective: Potential Increased Frequency, Possible Causes, and a Potential Emergency to Be Addressed

2021 ◽  
Vol 9 ◽  
Author(s):  
Maria E. Street ◽  
Chiara Sartori ◽  
Cecilia Catellani ◽  
Beatrice Righi
Keyword(s):  
Endocrine Disruptors ◽  
Precocious Puberty ◽  
Life Style ◽  
Screen Time ◽  
The Real ◽  
Sleeping Habits ◽  
Insight Into

A significant increase in precocious puberty, rapidly progressive puberty and precocious menarche has been reported in Italy since the initial lockdown because of the pandemic, and this could represent a new emergency to be addressed during this pandemic. There is a need, therefore, for further understanding and research. Many causes could account for this. Initially, it was thought that the changes in life-style, in screen time, and sleeping habits could be the cause but if considered individually these are insufficient to explain this phenomenon. Likely, changes in central nervous mediators, and an increase in catecholamines could contribute as a trigger, however, these aspects are poorly studied and understood as well as the real perceptions of these children. Finally, staying more indoors has certainly exposed these children to specific contaminants working as endocrine disruptors which could also have had an effect. It would be of utmost importance to compare this phenomenon worldwide with appropriate studies in order to verify what is happening, and gain a new insight into the consequences of the covid-19 pandemic and into precocious puberty and for future prevention.

scholarly journals Detecting and Profiling Endogenous RNA G-Quadruplexes in the Human Transcriptome

2021 ◽  
Vol 22 (15) ◽  
pp. 8012
Author(s):  
Rongxin Zhang ◽  
Yajun Liu ◽  
Xingxing Zhang ◽  
Ke Xiao ◽  
Yue Hou ◽  
...  
Keyword(s):  
Bioinformatics Analysis ◽  
Biological Functions ◽  
Bioinformatics Pipeline ◽  
The Real ◽  
Human Transcriptome ◽  
Gene Sets ◽  
Nucleic Acid Structures ◽  
Regulatory Functions ◽  
Whole Transcriptome ◽  
Insight Into

G-quadruplexes are the non-canonical nucleic acid structures that are preferentially formed in G-rich regions. This structure has been shown to be associated with many biological functions. Regardless of the broad efforts on DNA G-quadruplexes, we still have limited knowledge on RNA G-quadruplexes, especially in a transcriptome-wide manner. Herein, by integrating the DMS-seq and the bioinformatics pipeline, we profiled and depicted the RNA G-quadruplexes in the human transcriptome. The genes that contain RNA G-quadruplexes in their specific regions are significantly related to immune pathways and the COVID-19-related gene sets. Bioinformatics analysis reveals the potential regulatory functions of G-quadruplexes on miRNA targeting at the scale of the whole transcriptome. In addition, the G-quadruplexes are depleted in the putative, not the real, PAS-strong poly(A) sites, which may weaken the possibility of such sites being the real cleaved sites. In brief, our study provides insight into the potential function of RNA G-quadruplexes in post-transcription.

scholarly journals Twitter content classification

First Monday ◽  
2010 ◽  
Author(s):  
Stephen Dann
Keyword(s):  
Grounded Theory ◽  
Real World ◽  
Classification Scheme ◽  
Theory Analysis ◽  
The Real ◽  
Real World Application ◽  
Classification Framework ◽  
Content Classification ◽  
Insight Into

This paper delivers a new Twitter content classification framework based sixteen existing Twitter studies and a grounded theory analysis of a personal Twitter history. It expands the existing understanding of Twitter as a multifunction tool for personal, profession, commercial and phatic communications with a split level classification scheme that offers broad categorization and specific sub categories for deeper insight into the real world application of the service.

scholarly journals OHM’S LAW: MISCONCEPTIONS OF THE STUDENTS AT SECONDARY AND SENIOR SECONDARY LEVEL

2021 ◽  
Vol 5 (12) ◽  
Author(s):  
Yogesh Popat
Keyword(s):  
Secondary Level ◽  
The Real ◽  
Ohm’S Law ◽  
Ohm's Law ◽  
Class Room ◽  
Senior Secondary ◽  
Insight Into

The purpose of this study is to reveal the misconceptions towards the understating of ohm’s law. The sample used consists of 40 students of class X studying the Physics of CBSE curriculum. Data is collected based on essay, class room discussion and Viva-Voce. From the results of this paper it can be concluded that the students do not understands the real and actual concepts of ohm’s of by merely reading the curriculum books and by performing the experiments in school lab. The results also reflect that the misconception may also arise due to the misinterpretation of language of physics in relation to electro properly. This paper is the reflection of teaching ohm’s law in the classroom in which the students generally gets confused and develops the wrong concepts at secondary and senior secondary level. The results, discussion and conclusion in this paper will also help the teachers to develop the students’ insight into the nature of physics.

scholarly journals Does Theory Advance with Technology?

1990 ◽  
Vol 123 ◽  
pp. 409-412
Author(s):  
Halton Arp
Keyword(s):  
Cutting Edge ◽  
Extragalactic Astronomy ◽  
The Real ◽  
The Universe ◽  
Insight Into

Observational technology in astronomy moves ahead. We can see a thousand times fainter and ten to a hundred times more detail than 40 years ago. But does our application to research match the engineering progress? Most of us make the easy assumption that theory is right at the cutting edge, waiting to gobble up each new fact into an even deeper, more detailed insight into the universe. But humans frequently misunderstand the real problems and misapply technology - making everything worse for agonizingly long times.Is it possible that extragalactic astronomy has serious misconceptions? The key point to appreciate is that its whole structure rests on the belief that we know the distances to objects in the universe. The simple shift to the red of the spectrum of any observed object is assumed to measure its distance. But for 25 years evidence has been increasing that drastically incorrect distances can result. Unfortunately, not only quasar distances but the distances to the vast majority of galaxies also depend on redshifts.

Three Weeks in Isolation with Two Chronic Schizophrenic Patients

1977 ◽  
Vol 131 (5) ◽  
pp. 504-513 ◽  
Author(s):  
Roger Morgan
Keyword(s):  
Real Time ◽  
The Real ◽  
Chronic Schizophrenic ◽  
Patient Interaction ◽  
Schizophrenic Patients ◽  
Natural Outcome ◽  
Insight Into

SummaryAn account is given of impressions and observations collected during three weeks in November 1975 which the writer spent with two of his chronic schizophrenic patients in a purpose-built isolation unit inside which it was impossible to have any idea of the real time.This experience gave the observer an unusually close view of schizophrenic and institutional behaviour and some insight into the natural outcome of staff-patient interaction.

Japanese Children's Understanding of the Distinction Between Real and Apparent Emotion

1988 ◽  
Vol 11 (2) ◽  
pp. 203-218 ◽  
Author(s):  
D. Gardner ◽  
P. L. Harris ◽  
M. Ohmoto ◽  
T. Hamazaki
Keyword(s):  
Negative Emotion ◽  
The Real ◽  
The Difference ◽  
Insight Into ◽  
Cognitive Competency

Japanese children's understanding of the difference between real and apparent emotion was investigated in a replication of Harris, Donnelly, Guz and Pitt-Watson (1986). Children aged 4 and 6 years listened to stories featuring a protagonist in a situation where it would be appropriate to really feel a positive or negative emotion and to mask that emotion. Subjects were then asked about the real emotion felt and the apparent emotion shown by the protagonist. The results demonstrated that 6-year-olds understand the distinction between real and apparent emotion more systematically than 4-year-olds. A comparison with the performance of English children supports the conclusion that insight into the distinction between real and apparent emotion is dependent upon an underlying cognitive competency and relatively unaffected by socialisation differences.

Social Reform and the Divided Conscience of Antebellum Protestantism

1979 ◽  
Vol 48 (4) ◽  
pp. 416-430 ◽  
Author(s):  
James H. Moorhead
Keyword(s):  
Nineteenth Century ◽  
Human Nature ◽  
Social Reform ◽  
The Other ◽  
The Real ◽  
Intimate Connection ◽  
Fertile Soil ◽  
Great Force ◽  
Insight Into

It is a commonplace of antebellum historiography that the numerous reforms of the age often bore an intimate connection with Protestant evangelicalism, and Charles Grandison Finney is often portrayed as a symbol of this link. In addition to endorsing such causes as antislavery and temperance, the great evangelist inspired numerous converts to work out their salvation through useful service, including reform; and the areas swept by his revivals provided fertile soil for every manner of ultraism. Both as theological innovator and religious activist, he seemed to epitomize a tide of perfectionist optimism surging with great force against institutional restraints.Yet there was a very cautious side to Finney. He seldom committed himself unreservedly to any cause other than revivalism and generally eschewed the most controversial approaches to reform. Viewing this aspect of his career, one scholar has recently argued that “the basic thrust of Finney's thought and activity was conservative, status conscious, and pessimistic about human nature.” Because of these two faces, the historian is tempted to fix on one or the other as the “real” Finney, but it is more profitable to probe his ambiguities than to mitigate them. An examination of Finney offers fruitful insight into nineteenth-century evangelicalism's explosive potential for reform and its equally powerful tendency to limit and contain that impulse.

The evaluation of possible role of endocrine disruptors in central and peripheral precocious puberty

2016 ◽  
Vol 26 (7) ◽  
pp. 493-500 ◽  
Author(s):  
Ayşe Derya Buluş ◽  
Ali Aşci ◽  
Pinar Erkekoglu ◽  
Aylin Balci ◽  
Nesibe Andiran ◽  
...  
Keyword(s):  
Endocrine Disruptors ◽  
Precocious Puberty ◽  
Peripheral Precocious Puberty

scholarly journals Promoting youth mental health during the COVID-19 pandemic: A longitudinal study

PLoS ONE ◽  
2021 ◽  
Vol 16 (8) ◽  
pp. e0255294
Author(s):  
Maya L. Rosen ◽  
Alexandra M. Rodman ◽  
Steven W. Kasparek ◽  
Makeda Mayes ◽  
Malila M. Freeman ◽  
...  
Keyword(s):  
Mental Health ◽  
News Media ◽  
Screen Time ◽  
Mental Health Problems ◽  
Externalizing Psychopathology ◽  
Wide Range ◽  
The Face ◽  
Internalizing And Externalizing ◽  
Insight Into ◽  
At Home

The COVID-19 pandemic has introduced novel stressors into the lives of youth. Identifying factors that protect against the onset of psychopathology in the face of these stressors is critical. We examine a wide range of factors that may protect youth from developing psychopathology during the pandemic. We assessed pandemic-related stressors, internalizing and externalizing psychopathology, and potential protective factors by combining two longitudinal samples of children and adolescents (N = 224, 7–10 and 13–15 years) assessed prior to the pandemic, during the stay-at-home orders, and six months later. We evaluated how family behaviors during the stay-at-home orders were related to changes in psychopathology during the pandemic, identified factors that moderate the association of pandemic-related stressors with psychopathology, and determined whether associations varied by age. Internalizing and externalizing psychopathology increased substantially during the pandemic. Higher exposure to pandemic-related stressors was associated with increases in internalizing and externalizing symptoms early in the pandemic and six months later. Having a structured routine, less passive screen time, lower exposure to news media about the pandemic, and to a lesser extent more time in nature and getting adequate sleep were associated with reduced psychopathology. The association between pandemic-related stressors and psychopathology was reduced for youths with limited passive screen time and was absent for children, but not adolescents, with lower news media consumption related to the pandemic. We provide insight into simple, practical steps families can take to promote resilience against mental health problems in youth during the COVID-19 pandemic and protect against psychopathology following pandemic-related stressors.

scholarly journals Philosophy of education - Uzelac Milan: Philosophy of education, Institute for Textbooks, Belgrade, 2016

2020 ◽  
Vol 54 (3) ◽  
pp. 1039-1052
Author(s):  
Aleksandar Petrović
Keyword(s):  
Educational System ◽  
Philosophy Of Education ◽  
The State ◽  
Historical Aspects ◽  
The Real ◽  
Insight Into

Milan Uzelac, the author of this study, has written a broad insight into the problem of education itself with detailed and elaborated moments that constitute its social and historical aspects. What the author reaches is the real reflection of the state in today's educational system, and almost causes disappointment, but the feeling of hopelessness creates an insight into the meaning of the notion itself, from where the idea of being educated rises to the highest plane of observation.

Sign in / Sign up

Export Citation Format

Share Document