scholarly journals Corrigendum: Shock Index, Pediatric Age-Adjusted Predicts Morbidity and Mortality in Children Admitted to the Intensive Care Unit

2021 ◽  
Vol 9 ◽  
Author(s):  
Kuo-Chen Huang ◽  
Ying Yang ◽  
Chao-Jui Li ◽  
Fu-Jen Cheng ◽  
Ying-Hsien Huang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Morbidity And Mortality ◽  
Pediatric Age ◽  
Shock Index

scholarly journals Shock Index, Pediatric Age-Adjusted Predicts Morbidity and Mortality in Children Admitted to the Intensive Care Unit

2021 ◽  
Vol 9 ◽  
Author(s):  
Kuo-Chen Huang ◽  
Ying Yang ◽  
Chao-Jui Li ◽  
Fu-Jen Cheng ◽  
Ying-Hsien Huang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Inotropic Support ◽  
Morbidity And Mortality ◽  
Pediatric Age ◽  
Shock Index ◽  
Patient Age ◽  
Early Management ◽  
Icu Admission ◽  
Patient Âgé

Background: The shock index, pediatric age-adjusted (SIPA), defined as the maximum normal heart rate divided by the minimum normal systolic blood pressure by age, can help predict the risk of morbidity and mortality after pediatric trauma. This study investigated whether the SIPA can be used as an early index of prognosis for non-traumatic children visiting the pediatric emergency department (ED) and were directly admitted to the intensive care unit (ICU). We hypothesized that an increase in SIPA values in the first 24 h of ICU admission would correlate with mortality and adverse outcomes.Methods: This multicenter retrospective study enrolled non-traumatic patients aged 1–17 years who presented to the pediatric ED and were directly admitted to the ICU from January 1, 2016, to December 31, 2018, in Taiwan. The SIPA value was calculated at the time of arrival at the ED and 24 h after ICU admission. Cutoffs included SIPA values >1.2 (patient age: 1–6), >1.0 (patient age: 7–12), and >0.9 (patient age: 12–17). The utility of the SIPA and the trends in the SIPA during the first 24 h of ICU admission were analyzed to predict outcomes.Results: In total, 1,732 patients were included. Of these, 1,050 (60.6%) were under 6 years old, and the median Pediatric Risk of Mortality score was 7 (5–10). In total, 4.7% of the patients died, 12.9% received mechanical ventilator (MV) support, and 11.1% received inotropic support. The SIPA value at 24 h after admission was associated with increased mortality [odds ratio (OR): 4.366, 95% confidence interval (CI): 2.392–7.969, p < 0.001], MV support (OR: 1.826, 95% CI: 1.322–2.521, p < 0.001), inotropic support (OR: 2.306, 95% CI: 1.599–3.326, p < 0.001), and a long hospital length of stay (HLOS) (2.903 days, 95% CI: 1.734–4.271, p < 0.001). Persistent abnormal SIPA value was associated with increased mortality (OR: 2.799, 95% CI: 1.566–5.001, p = 0.001), MV support (OR: 1.457, 95% CI: 1.015–2.092, p = 0.041), inotropic support (OR: 1.875, 95% CI: 1.287–2.833, p = 0.001), and a long HLOS (3.2 days, 95% CI: 1.9–4.6, p < 0.001). Patients with abnormal to normal SIPA values were associated with decreased mortality (OR: 0.258, 95% CI: 0.106–0.627, p = 0.003), while patients with normal to abnormal SIPA values were associated with increased mortality (OR: 3.055, 95% CI: 1.472–5.930, p = 0.002).Conclusions: In non-traumatic children admitted to the ICU from the ED, increased SIPA values at 24 h after ICU admission predicted high mortality and bad outcomes. Monitoring the trends in the SIPA could help with prognostication and optimize early management.

scholarly journals Corrigendum: Shock Index, Pediatric Age-Adjusted Predicts Morbidity and Mortality in Children Admitted to the Intensive Care Unit

2021 ◽  
Vol 9 ◽  
Author(s):  
Kuo-Chen Huang ◽  
Ying Yang ◽  
Chao-Jui Li ◽  
Fu-Jen Cheng ◽  
Ying-Hsien Huang ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Morbidity And Mortality ◽  
Pediatric Age ◽  
Shock Index

scholarly journals Healthcare-Associated Infections among Patients in a Large Burn Intensive Care Unit: Incidence and Pathogens, 2008–2012

2014 ◽  
Vol 35 (10) ◽  
pp. 1304-1306 ◽  
Author(s):  
David J. Weber ◽  
David van Duin ◽  
Lauren M. DiBiase ◽  
Charles Scott Hultman ◽  
Samuel W. Jones ◽  
...  
Keyword(s):  
United States ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
The United States ◽  
Burn Injuries ◽  
Morbidity And Mortality ◽  
Common Source ◽  
Healthcare Associated Infections ◽  
Burn Patients ◽  
Healthcare Associated

Burn injuries are a common source of morbidity and mortality in the United States, with an estimated 450,000 burn injuries requiring medical treatment, 40,000 requiring hospitalization, and 3,400 deaths from burns annually in the United States. Patients with severe burns are at high risk for local and systemic infections. Furthermore, burn patients are immunosuppressed, as thermal injury results in less phagocytic activity and lymphokine production by macrophages. In recent years, multidrug-resistant (MDR) pathogens have become major contributors to morbidity and mortality in burn patients.Since only limited data are available on the incidence of both device- and nondevice-associated healthcare-associated infections (HAIs) in burn patients, we undertook this retrospective cohort analysis of patients admitted to our burn intensive care unit (ICU) from 2008 to 2012.

scholarly journals The impact of metabolic syndrome on morbidity and mortality among intensive care unit admitted COVID-19 patients

2020 ◽  
Vol 14 (6) ◽  
pp. 1979-1986
Author(s):  
Nasser Malekpour Alamdari ◽  
Fateme Sadat Rahimi ◽  
Siamak Afaghi ◽  
Afshin Zarghi ◽  
Shohra Qaderi ◽  
...  
Keyword(s):  
Metabolic Syndrome ◽  
Intensive Care Unit ◽  
Intensive Care ◽  
Morbidity And Mortality ◽  
The Impact

scholarly journals The occurrence of adverse events is associated with increased morbidity and mortality in children admitted to a single pediatric intensive care unit

2019 ◽  
Vol 179 (3) ◽  
pp. 473-482
Author(s):  
Pablo G. Eulmesekian ◽  
Juan P. Alvarez ◽  
José M. Ceriani Cernadas ◽  
Augusto Pérez ◽  
Stefanía Berberis ◽  
...  
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Adverse Events ◽  
Pediatric Intensive Care Unit ◽  
Pediatric Intensive Care ◽  
Morbidity And Mortality

Effects of Sepsis on Morbidity and Mortality in Critically Ill Patients 2 Years After Intensive Care Unit Discharge

2019 ◽  
Vol 28 (6) ◽  
pp. 424-432 ◽  
Author(s):  
Livia Biason ◽  
Cassiano Teixeira ◽  
Jaqueline Sangiogo Haas ◽  
Cláudia da Rocha Cabral ◽  
Gilberto Friedman
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Critically Ill ◽  
Critically Ill Patients ◽  
Intensive Care Unit Discharge ◽  
Morbidity And Mortality ◽  
Unit Discharge

scholarly journals COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation

2020 ◽  
Vol 2020 ◽  
pp. 1-4 ◽  
Author(s):  
Habiba Hussain ◽  
Matthew Sehring ◽  
Bhagat Singh Aulakh
Keyword(s):  
Intensive Care Unit ◽  
Intensive Care ◽  
Case Report ◽  
Severe Acute Respiratory Syndrome ◽  
Hospital Stay ◽  
Inflammatory Markers ◽  
Morbidity And Mortality ◽  
Management Guidelines ◽  
Disease Prognosis ◽  
Therapeutic Anticoagulation

The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay.

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