scholarly journals Kaempferia galanga L.: Progresses in Phytochemistry, Pharmacology, Toxicology and Ethnomedicinal Uses

2021 ◽  
Vol 12 ◽  
Author(s):  
Si-Yu Wang ◽  
Hui Zhao ◽  
Hong-Tao Xu ◽  
Xiao-Dong Han ◽  
Yun-Shan Wu ◽  
...  
Keyword(s):  
Web Of Science ◽  
Chinese Herb ◽  
Pharmacological Activities ◽  
Cyclic Dipeptides ◽  
Kaempferia Galanga ◽  
Traditional Chinese Herb ◽  
Anti Oxidant ◽  
Pharmacology And Toxicology ◽  
Ethnomedicinal Uses ◽  
Chinese Herb Medicine

K. galanga is an aromatic medicinal herb. It is locally to India and distributed in China, Myanmar, Indonesia, Malaysia, and Thailand. K. galanga is a Traditional Chinese Herb Medicine (TCHM), which has been applied to treat cold, dry cough, toothaches, rheumatism, hypertension and so on. In addition, it has been used widely as spices since its highly aromas. The aim of this review is to compile and update the current progresses of ethnomedicinal uses, phytochemistry, pharmacology and toxicology of K. galanga. All the data on K. galanga were based on different classical literary works, multiple electronic databases including SciFinder, Web of Science, PubMed, etc. The results showed that ninety-seven compounds have been identified from rhizome of K. galanga, including terpenoids, phenolics, cyclic dipeptides, flavonoids, diarylheptanoids, fatty acids and esters. Modern pharmacology studies revealed that extracts or secondary metabolites of the herb possessed anti-inflammatory, anti-oxidant, anti-tumorous, anti-bacterial, and anti-angiogenesis effects, which were closely related to its abundant ethnomedicinal uses. In conclusion, although previous research works have provided various information of K. galanga, more in-depth studies are still necessary to systemically evaluate phytochemistry, pharmacological activities, toxicity and quality control of this herb.

Anti-Inflammatory Function of Nodosin via Inhibition of IL-2

2010 ◽  
Vol 38 (01) ◽  
pp. 127-142 ◽  
Author(s):  
Jiyu Li ◽  
Junming Du ◽  
Lijuan Sun ◽  
Jianwen Liu ◽  
Zhiwei Quan
Keyword(s):  
Clinical Trial ◽  
T Lymphocytes ◽  
Mrna Level ◽  
Chinese Herb ◽  
Potential Candidate ◽  
Traditional Chinese Herb ◽  
Anti Inflammatory ◽  
Cell Mitosis ◽  
Herb Medicine ◽  
Chinese Herb Medicine

In order to explore the anti-inflammatory effects of Nodosin from Isodon serra, a traditional Chinese herb medicine, mouse T lymphocytes were incubated with Nodosin. In the current study, Nodosin suppressed the overproduction of the T lymphocytes; moreover, cell mitosis cycle was modulated by interfering with DNA replication in G1 stages via inhibition of IL-2 cytokine secretion at the mRNA level by Nodosin. Interestingly, Xylene-induced mouse tumescence model results suggested Nodosin depressed the murine ear-swelling extent and the level of IL-2 in the blood serum. Finally, Nodosin possessed significant anti-inflammatory effects and is a potential candidate for further clinical trial.

scholarly journals Ethnomedicinal Uses, Phytochemistry and Pharmacological Activities of Pittosporum floribundum Wight. & Arn. – A Review

2020 ◽  
pp. 48-55
Author(s):  
Kishangiri Kirtigiri Gunsai ◽  
Abhay Jayprakash Gandhi ◽  
Rabinarayan Acharya ◽  
V. J. Shukla
Keyword(s):  
Methanolic Extract ◽  
Stem Bark ◽  
Extensive Literature ◽  
Phytochemical Screening ◽  
Pharmacological Activities ◽  
Medicinal Uses ◽  
Anti Oxidant ◽  
Ethnobotanical Uses ◽  
Ethnomedicinal Uses ◽  
Different Parts

Objectives: Pittosporum floribundum Wight & Arn. (Pittosporaceae) has been associated with many therapeutic claims, especially for its ethnomedicinal and economical uses. In this review, an extensive literature survey was carried out to compile information available about its medicinal uses, phytochemistry and pharmacological properties. Materials and Methods: Ethnobotanical uses of P. floribundum reported in available books on ethnobotany and ethnomedicinal research articles have been compiled. The obtained data are arranged in a tabular form, enlisting its local names, their area of presence and parts used. Therapeutic indications, external or internal dosage form and usage of the drug are also noted. Results and Discussion: It was found that stem bark, leaves, and root of P. floribundum are used to combat itching, rheumatism, leprosy, sprain, eczema, arthritis, diabetes, chest pain and antidote for snake bite. Bark has maximum applications in leprosy, and sprain. The extracts of the different parts were subjected to phytochemical screening for the presence of phytoconstituents such as alkaloids, flavonoids, phenols, lignins, anthroquinones, steroids, tannins, saponins, fixed oils and glycosides. Studies have shown that the methanolic extract of bark having promising antifungal, antibacterial, anti-inflammatory, antioxidant, hepatoprotective, neuropharmacological and behaviour activities. Conclusion: P. floribundum has multifaceted uses in varied aspects thus underlining its significance. Reported claimed anti-bacterial and anti-oxidant activities can be further strengthened through pharmacological and clinical studies to establish the ethnic claims like leprosy, sprain, bruises, sciatica, pulmonary affection and phthisis.

A comprehensive review on the ethnobotany, phytochemistry, pharmacology, and toxicology of Mentha aquatic L (water mint) as a wild shallow vegetable

2021 ◽  
Vol 27 ◽  
Author(s):  
Farzaneh Asadollah-Pour ◽  
Asieh Jokar ◽  
Ebrahim Nasiri ◽  
Mohammad Azadbakht ◽  
Zohreh Bari ◽  
...  
Keyword(s):  
Intestinal Parasites ◽  
Phytochemical Analysis ◽  
Pharmacological Activities ◽  
Future Studies ◽  
Mentha Aquatica ◽  
Food Industries ◽  
Perennial Plant ◽  
Anti Oxidant ◽  
Intestinal Worms ◽  
Pharmacology And Toxicology

: Mentha spp. are aromatic plants and have been used in the medical, cosmetics, and food industries. These plants have been used as a traditional herbal medicine for various types of diseases. Mentha aquatica L. (water mint) is a perennial plant used as a wild vegetable and a culinary herb. As its name suggests, it grows in the shallow margins and channels of streams, rivers, wet meadows, etc. It has been used as a tonic plant, sedative, and soothing for intestinal parasites, constipation, diarrhea, stomach troubles, biliousness, liver diseases, impotence, low or high blood pressure, expelling intestinal worms in children, enhancing longevity. Researchers from all over the world have studied the chemical composition and pharmacological activities of this plant, such as its anti-microbial, anti-inflammatory, anti-oxidant activities. In addition, the neurochemical properties, larvicidal activity and phytochemical analysis of the plant have also been reported. However, there is no review article available that gathers all the information and provides insights for future studies on M. aquatica. Against this backdrop, the present research is conducted to categorize the published studies and to offer more suggestions to researchers for future studies.

­­Ethnobotany, phytochemistry, pharmacognostic and pharmacological aspects of Cordia macleodii Hook.f. & Thomson - A review

2016 ◽  
Vol 23 (2) ◽  
pp. 67-71
Author(s):  
Pranati Nayak ◽  
Chinnamadasamy Kalidass
Keyword(s):  
Tamil Nadu ◽  
Chemical Constituents ◽  
Deciduous Forests ◽  
Pharmacological Activities ◽  
Peninsular India ◽  
Ethnomedicinal Plant ◽  
Hydroxyphenylacetic Acid ◽  
Anti Oxidant ◽  
Healing Wounds ◽  
Ethnomedicinal Uses

Cordia macleodii Hook.f. & Thomson is an important ethnomedicinal plant of India. It is found in the moist and dry deciduous forests of peninsular India such as Odisha, Madhya Pradesh, Chhattisgarh, Tamil Nadu etc. The plant is used ethnomedicinally for various purposes like healing wounds, mouth sores, treating jaundice and also as an aphrodisiac by the tribal people where it is found. Its pharmacological activities include anti-microbial, wound healing, anti-oxidant and hepatoprotective, anti snake venom, analgesic and anti-inflammatory activity. Many phytocompounds like quercetin, p-hydroxyphenylacetic acid and phytosterols such as β-sitosterol, stigmasterol, camphesterol and Cholest-5-EN-3OL (3β)-Carbonyl chlorinated are isolated from this plant. The present work aims at presenting a comprehensive of the plants botany, ethnomedicinal uses, chemical constituents, pharmacognostic and pharmacological uses. The information reported in this work contributes scientifically to recognizing the importance of Cordia macleodii as a target in the search for new biotechnological investments.

Correction of malignant behavior of tumor cells by traditional Chinese herb medicine through a restoration of p53

2006 ◽  
Vol 233 (2) ◽  
pp. 315-327 ◽  
Author(s):  
Win-Ping Deng ◽  
Ming-Wei Chao ◽  
Wen-Fu Lai ◽  
Chi Sun ◽  
Chen-Yen Chung ◽  
...  
Keyword(s):  
Tumor Cells ◽  
Chinese Herb ◽  
Traditional Chinese Herb ◽  
Malignant Behavior ◽  
Herb Medicine ◽  
Chinese Herb Medicine

scholarly journals Mallotus philippensis (Lam.) Müll. Arg.: A review on its pharmacology and phytochemistry

2020 ◽  
Vol 10 (1) ◽  
pp. 31-50
Author(s):  
Abhishek Kumar ◽  
Meenu Patil ◽  
Pardeep Kumar ◽  
Ram Chand Bhatti ◽  
Rupinder Kaur ◽  
...  
Keyword(s):  
Drug Discovery ◽  
Present Article ◽  
Web Of Science ◽  
Biological Activities ◽  
Pharmacological Activities ◽  
Promising Candidate ◽  
Natural Origin ◽  
Different Types ◽  
Anti Oxidant

Kamala tree (Mallotus philippensis) is traditionally used by different ethnic groups to treat a variety of diseases and health ailments. However, these traditional uses need to be scientifically investigated and validated in order to develop drugs from this tree. Therefore, the present article is aimed to review the scientifically validated knowledge on the pharmacology and phytochemistry of the tree. To accomplish this, we extensively surveyed the available databases like Scopus, Web of Science, Google Scholar, ScienceDirect, NCBI including PubMed and PubChem, etc. by using keywords ‘Mallotus philippensis’, ‘Mallotus phillippinensis’ and ‘Mallotus philippinensis’. Our results indicated that the tree possesses more than 50 different types of important phytochemicals of natural origin. The wide array of phytochemicals possesses fascinating biological activities like anthelmintic, antibacterial, anti-inflammatory, anti-oxidant, anti-cancerous, anti-tuberculosis, anti-parasitic, analgesic, anti-urolithiatic and anti-viral activities. Thus, pharmacological activities and isolation of active phytochemicals make the tree a promising candidate for drug discovery. However, pharmacological activities such as antibacterial and anti-oxidant activities are often tested with crude extracts and in vitro rudimentary methods that can be sometimes misleading and non-specific. Thus, more sophisticated techniques may be applied for the isolation of active chemicals and elucidating their mechanism of actions.

Ethnomedicinal uses, Phytochemistry and Pharmacological Aspects of the Genus Berberis Linn: A Comprehensive Review

2020 ◽  
Vol 23 ◽  
Author(s):  
Roohi Mohi-ud-din ◽  
Reyaz Hassan Mir ◽  
Prince Ahad Mir ◽  
Saeema Farooq ◽  
Syed Naiem Raza ◽  
...  
Keyword(s):  
Chemical Constituents ◽  
Pharmacological Activities ◽  
Traditional Use ◽  
Comprehensive Review ◽  
Wide Range ◽  
Anti Cancer ◽  
Comprehensive Survey ◽  
Ethnomedicinal Uses

Background: Genus Berberis (family Berberidaceae), which contains about 650 species and 17 genera worldwide, has been used in folklore and various traditional medicine systems. Berberis Linn. is the most established group among genera with around 450-500 species across the world. This comprehensive review will not only help researchers for further evaluation but also provide substantial information for future exploitation of species to develop novel herbal formulations. Objective: The present review is focussed to summarize and collect the updated review of information of Genus Berberis species reported to date regarding their ethnomedicinal information, chemical constituents, traditional/folklore use, and reported pharmacological activities on more than 40 species of Berberis. Conclusion: A comprehensive survey of the literature reveals that various species of the genus possess various phytoconstituents mainly alkaloids, flavonoid based compounds isolated from different parts of a plant with a wide range of pharmacological activities. So far, many pharmacological activities like anti-cancer, anti-hyperlipidemic, hepatoprotective, immunomodulatory, anti-inflammatory both in vitro & in vivo and clinical study of different extracts/isolated compounds of different species of Berberis have been reported, proving their importance as a medicinal plant and claiming their traditional use.

Bryophyllum Pinnatum: A Review on Medicinal Benefits and Potent Bioactive Molecules

2020 ◽  
Vol 16 (7) ◽  
pp. 978-992
Author(s):  
Punit Kumar ◽  
Sujata Malik ◽  
Kashyap K. Dubey
Keyword(s):  
Web Of Science ◽  
Folk Medicine ◽  
Bioactive Molecules ◽  
Phytochemical Analysis ◽  
Traditional Herbal Medicine ◽  
Pharmacological Activities ◽  
Online Databases ◽  
Natural Remedies ◽  
Medicinal Properties ◽  
Bryophyllum Pinnatum

Background: Since its inception, people are using herbal extracts as natural remedies for the treatment of various diseases. Bryophyllum pinnatum, also known as the air plant, is a well-recognized herb used in folk medicine. It is native to Madagascar and further planted in tropical and subtropical areas around the world. It is known for the profusion of miniature plantlets which arise from the margins of phylloclade. Objective: The aim of this review is to provide the information regarding local and traditional uses, pharmacological activities and different phytochemicals reported from leaves extracts of Bryophyllum pinnatum. Methods: This review article contains a detailed survey of the literature about Bryophyllum pinnatum available in different online databases, such as; PubMed, Web of Science, Science Direct, Elsevier, and Google Scholar, etc. In this review, authors have focused on ethnopharmacological importance and phytochemicals present in Bryophyllum pinnatum and their structure. The structures of the phytochemical were prepared by the ChemDraw tool. Results: This plant is used as a traditional herbal medicine around the globe due to medicinal properties like; anthelmintic, immunosuppressive, hepatoprotective, antinociceptive, anti-inflammatory, antidiabetic, nephroprotective, antioxidant, antimicrobial, analgesic, anticonvulsant and antipyretic. Phytochemical analysis revealed the presence of many bioactive compounds like; alkaloids, flavonoids, triterpenes, steroids, glycosides, bufadienolides, lipids, and organic acids, etc. which are associated with different medicinal properties. Conclusion: Bryophyllum pinnatum possesses diverse pharmacological importance and remarkable medicinal properties. Investigators have reported a large number of phytochemicals exhibiting different medicinal properties and correlation of medicinal properties.

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