scholarly journals Convergence of Precision Medicine and Public Health Into Precision Public Health: Toward a Big Data Perspective

2021 ◽  
Vol 9 ◽  
Author(s):  
Pedro Elkind Velmovitsky ◽  
Tatiana Bevilacqua ◽  
Paulo Alencar ◽  
Donald Cowan ◽  
Plinio Pelegrini Morita
Keyword(s):  
Public Health ◽  
Big Data ◽  
Precision Medicine ◽  
Health Data ◽  
Use Cases ◽  
The Other ◽  
Data Types ◽  
Holistic View ◽  
Precision Public Health ◽  
Other Hand

The field of precision medicine explores disease treatments by looking at genetic, socio-environmental, and clinical factors, thus trying to provide a holistic view of a person's health. Public health, on the other hand, is focused on improving the health of populations through preventive strategies and timely interventions. With recent advances in technology, we are able to collect, analyze and store for the first-time large volumes of real-time, diverse and continuous health data. Typically, the field of precision medicine deals with a huge amount of data from few individuals; public health, on the other hand, deals with limited data from a population. With the coming of Big Data, the fields of precision medicine and public health are converging into precision public health, the study of biological and genetic factors supported by large amounts of population data. In this paper, we explore through a comprehensive review the data types and use cases found in precision medicine and public health. We also discuss how these data types and use cases can converge toward precision public health, as well as challenges and opportunities provided by research and analyses of health data.

scholarly journals Big data hurdles in precision medicine and precision public health

2018 ◽  
Vol 18 (1) ◽  
Author(s):  
Mattia Prosperi ◽  
Jae S. Min ◽  
Jiang Bian ◽  
François Modave
Keyword(s):  
Public Health ◽  
Big Data ◽  
Precision Medicine ◽  
Precision Public Health

scholarly journals Advancing precision public health using human genomics: examples from the field and future research opportunities

2021 ◽  
Vol 13 (1) ◽  
Author(s):  
Megan C. Roberts ◽  
Alison E. Fohner ◽  
Latrice Landry ◽  
Dana Lee Olstad ◽  
Amelia K. Smit ◽  
...  
Keyword(s):  
Public Health ◽  
Precision Medicine ◽  
Behavioral Science ◽  
Public Health Research ◽  
Future Research ◽  
Human Genomics ◽  
Precision Public Health ◽  
Genomics Research ◽  
Health Initiatives ◽  
Public Health Initiatives

AbstractPrecision public health is a relatively new field that integrates components of precision medicine, such as human genomics research, with public health concepts to help improve population health. Despite interest in advancing precision public health initiatives using human genomics research, current and future opportunities in this emerging field remain largely undescribed. To that end, we provide examples of promising opportunities and current applications of genomics research within precision public health and outline future directions within five major domains of public health: biostatistics, environmental health, epidemiology, health policy and health services, and social and behavioral science. To further extend applications of genomics within precision public health research, three key cross-cutting challenges will need to be addressed: developing policies that implement precision public health initiatives at multiple levels, improving data integration and developing more rigorous methodologies, and incorporating initiatives that address health equity. Realizing the potential to better integrate human genomics within precision public health will require transdisciplinary efforts that leverage the strengths of both precision medicine and public health.

scholarly journals Biological Tools to Deal with Pollution : Selected Advances and Novel Perspectives

2014 ◽  
Vol 3 (1) ◽  
pp. 57
Author(s):  
Abdelaziz Ghanemi ◽  
Besma Boubertakh
Keyword(s):  
Public Health ◽  
Raw Materials ◽  
Economic Benefits ◽  
The Other ◽  
Environment And Public Health ◽  
The Public ◽  
Other Hand ◽  
Metabolic Properties ◽  
Living Organisms ◽  
The Impact

Pollution  represents  a  problem  common  to economy and  public  health. Indeed, the public health, because of the  divers’  type of pollutions, is facing divers challenges for which urgent solutions are required.The biology provides approaches not only to deal with the pollution, but also to  obtain  economic  benefits. Some living  organisms  have  particular metabolisms  that allow  them  to  assimilate  and  metabolite  the polluting agents  and thus reduce the  impact  they have on both environment  and public health.  On  the other  hand,  the  metabolic  properties  of  specific organisms make  the  polluting  elements raw materials to  synthesize  other elements that are benefits  for  economy  and  non-toxic  for  the  ecology and  the  biohealth. Yet, other options such as the regulations and laws are  required  to improve the efficiency of these approaches.

scholarly journals Beyond Public Health Genomics: Can Big Data and Predictive Analytics Deliver Precision Public Health?

2018 ◽  
Vol 21 (5-6) ◽  
pp. 244-250 ◽  
Author(s):  
Muin J. Khoury ◽  
Michael Engelgau ◽  
David A. Chambers ◽  
George A. Mensah
Keyword(s):  
Public Health ◽  
Big Data ◽  
Predictive Analytics ◽  
Public Health Genomics ◽  
Precision Public Health

Translanguaging and linguistic landscapes

2015 ◽  
Vol 1 (1-2) ◽  
pp. 54-74 ◽  
Author(s):  
Durk Gorter ◽  
Jasone Cenoz
Keyword(s):  
The Other ◽  
Holistic View ◽  
Linguistic Resources ◽  
School Settings ◽  
Other Hand ◽  
San Sebastian ◽  
The One ◽  
The Individual ◽  
Neighborhood Level

In this article we discuss the concept of translanguaging in relation to a holistic view of linguistic landscapes that goes beyond the analysis of individual signs. On the one hand, we look at instances of multilingual signage as a combination of linguistic resources. On the other hand, at the neighborhood level the individual signs combine, alternate and mix to shape linguistic landscapes as a whole. We expand our “Focus on Multilingualism” approach from school settings to the multilingual cityscape. One bookshop and its surrounding neighborhoods in Donostia-San Sebastián illustrate how readers navigate between languages and go across linguistic borders. Through translanguaging we foreground the co-occurrence of different linguistic forms, signs and modalities. At the level of neighborhood emerges the space in which translanguaging goes outside the scope of single signs and separate languages. We conclude that translanguaging is an approach to linguistic landscapes that takes the study of multilingualism forward.

scholarly journals Method for a cloud based remaining-service-life-prediction for vehicle-gearboxes based on big-data-analysis and machine learning

2020 ◽  
Vol 84 (4) ◽  
pp. 305-314
Author(s):  
Daniel Vietze ◽  
Michael Hein ◽  
Karsten Stahl
Keyword(s):  
Machine Learning ◽  
Big Data ◽  
Service Life ◽  
Operating Time ◽  
The Other ◽  
Learning Approaches ◽  
State Of Health ◽  
Remaining Service Life ◽  
Other Hand ◽  
The One

AbstractMost vehicle-gearboxes operating today are designed for a limited service-life. On the one hand, this creates significant potential for decreasing cost and mass as well as reduction of the carbon-footprint. On the other hand, this causes a rising risk of failure with increasing operating time of the machine. Especially if a failure can result in a high economic loss, this fact creates a conflict of goals. On the one hand, the machine should only be maintained or replaced when necessary and, on the other hand, the probability of a failure increases with longer operating times. Therefore, a method is desirable, making it possible to predict the remaining service-life and state of health with as little effort as possible.Centerpiece of gearboxes are the gears. A failure of these components usually causes the whole gearbox to fail. The fatigue life analysis deals with the dimensioning of gears according to the expected loads and the required service-life. Unfortunately, there is very little possibility to validate the technical design during operation, today. Hence, the goal of this paper is to present a method, enabling the prediction of the remaining-service-life and state-of-health of gears during operation. Within this method big-data and machine-learning approaches are used. The method is designed in a way, enabling an easy transfer to other machine elements and kinds of machinery.

Aporia and Wonder in the Age of Big Data

2019 ◽  
Vol 23 (2) ◽  
pp. 137-152
Author(s):  
Murray Skees ◽  
Keyword(s):  
Social Media ◽  
Big Data ◽  
Media Use ◽  
Internet User ◽  
The Other ◽  
The Internet ◽  
Social Media Use ◽  
Other Hand

My argument in this paper is given in two parts. In Part I, I review the ancient understanding of aporia, focusing on works by Plato and Aristotle. I illustrate two ways of understanding aporia: “cathartic” and “zetetic.” Cathartic aporia refers to the experience of being purged of hubris and ignorance through the dialectic. Zetetic aporia, on the other hand, requires us to engage in, recognize, and work through certain philosophical puzzles or problems. In Part II, I discuss the idea of Big Data and then argue that in the “age of answers” neither conception of aporia appears to be necessarily cultivated by the average Internet user. Our experience of wonder suffers when we rely so heavily on the Internet as a “surrogate expert,” and when our social media use betrays the fact that we always seem to gravitate towards the like-minded.

Internet and Suicide

2011 ◽  
pp. 384-390
Author(s):  
Dianne Currier
Keyword(s):  
Public Health ◽  
Social Networks ◽  
Suicide Prevention ◽  
Interest Group ◽  
Information Resources ◽  
The Other ◽  
The Internet ◽  
Other Hand ◽  
Communities Of Interest ◽  
Public Health Officials

It is now commonly accepted that the appearance and expansion of Internet-based communication has given rise to new possibilities for forging social networks and establishing “communities of interest.” One such ‘interest group’ which has found a community online comprises those who wish to end their lives. This has become a cause for concern to public health officials, governments, and suicide prevention professionals, while on the other hand possibilities for outreach and prevention in the new medium are being explored. The ways in which suicidal individuals have availed themselves of the information resources and connective possibilities of the Internet are outlined below, along with how governments and other parties interested in suicide prevention have responded to this new domain of risk.

scholarly journals Evaluation of the use of PetrifilmTM EB count plates for the enumeration of Enterobacteriaceae in poultry samples

2012 ◽  
Vol 32 (3) ◽  
pp. 588-593
Author(s):  
Tainá Drebes ◽  
Cláudia Majolo ◽  
Hans Fröder
Keyword(s):  
Public Health ◽  
Conventional Method ◽  
Food Industry ◽  
The Other ◽  
Other Hand ◽  
Alternative Method ◽  
Significant Difference ◽  
Glucose Agar ◽  
Low Levels ◽  
Conventional Methods

A test that is rapid, simple, accurate, not expensive, gives rapid results, and is sensitive enough to detect low levels of microorganisms would be the most suitable for food industry routine laboratories, or even for a public health laboratories. A ready-to-use alternative, commercially available method is the PetrifilmTM EB method. The aim of this study was to evaluate whether there is a statistically significant difference between the conventional methods based on Violet Red Bile Glucose Agar and the alternative 3M TM Petrifilm (EB) method for the enumeration of Enterobacteriaceae in poultry carcasses. This study also assessed whether the alternative method showed ability to produce results that were directly proportional to the concentration of the target (approximately 270 colony-forming unit.mL-1). A total of 120 poultry carcasses samples showed a significant difference (p < 0.05) between the populations obtained by the two methods, and the conventional method showed low proportionality between the dilutions. On the other hand, the PetrifilmTM EB quantification system showed the capacity to produce results that are proportional to the concentration of the analyte in samples in the concentration range from 1 to 256 colony-forming unit.mL-1.

scholarly journals Precision Public Health for the Era of Precision Medicine

2016 ◽  
Vol 50 (3) ◽  
pp. 398-401 ◽  
Author(s):  
Muin J. Khoury ◽  
Michael F. Iademarco ◽  
William T. Riley
Keyword(s):  
Public Health ◽  
Precision Medicine ◽  
Precision Public Health
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