scholarly journals Preliminary Study of the Use of Root with Sedline® EEG Monitoring for Assessment of Anesthesia Depth in 6 Horses

2020 ◽  
Vol 10 (3) ◽  
pp. 1050
Author(s):  
Olga Drewnowska ◽  
Bernard Turek ◽  
Barbara Lisowska ◽  
Charles E. Short

Management of equine anesthesia monitoring is still a challenge. Careful monitoring to provide guidelines for anesthesia depth assessment currently relies upon eye signs, cardiopulmonary responses, and the level of muscle relaxation. Electroencephalography, as a non-invasive brain activity monitor, may be used to complement the routinely monitored physiologic parameters. Six horses, undergoing various surgical procedures and anesthesia protocols, were monitored with the use of a Root with Sedline EEG monitor and a routine monitor of life parameters. The life parameters were compared to the changes on the EEG density spectral array observed live during anesthesia. During all procedures the level of awareness was monitored using the EEG, with higher frequency and power of waves indicating a higher level of awareness. It was evident from this that there were variations according to the type of procedure and the anesthetic protocol. Cerebral activity was elevated during painful moments of the surgery and recovery, requiring adjustments in anesthetic concentrations. Evaluation of changes in the spectral edge frequency (SEF) could show the periods when the patient is stabilized. EEG monitoring has the potential to be used in clinical anesthesiology of horses. It was shown that this system may be used in horses under general anesthesia but is currently less effective in a standing horse for diagnostic or minor procedures.

2006 ◽  
Vol 54 (1) ◽  
pp. 35-42 ◽  
Author(s):  
P. Kruljc ◽  
Alenka Nemec

Clinically, the use of detomidine and butorphanol is suitable for sedation and deepening of analgosedation. The aim of our study was to establish the influence of detomidine used alone and a butorphanol-detomidine combination on brain activity and to evaluate and compare brain responses (using electroencephalography, EEG) by recording SEF90(spectral edge frequency 90%), individual brain wave fractions (beta, alpha, theta and delta) and electromyographic (EMG) changes in the left temporal muscle in standing horses. Ten clinically healthy cold-blooded horses were divided into two groups of five animals each. Group I received detomidine and Group II received detomidine followed by butorphanol 10 min later. SEF90, individual brain wave fractions and EMG were recorded with a pEEG (processed EEG) monitor using computerised processed electroencephalography and electromyography. The present study found that detomidine alone and the detomidine-butorphanol combination significantly reduced SEF90and EMG, and they caused changes in individual brain wave fractions during sedation and particularly during analgosedation. The EMG results showed that the detomidine-butorphanol combination provided greater and longer muscle relaxation. Our EEG and EMG results confirmed that the detomidine-butorphanol combination is safer and more appropriate forpainless and non-painless procedures on standing horses compared to detomidine alone.


2005 ◽  
Vol 20 (12) ◽  
pp. 3469-3475 ◽  
Author(s):  
N. Levek-Motola ◽  
Y. Soffer ◽  
L. Shochat ◽  
A. Raziel ◽  
L.M. Lewin ◽  
...  

2014 ◽  
Vol 22 ◽  
pp. S278-S279
Author(s):  
J. Podlipská ◽  
J.M. Koski ◽  
E. Liukkonen ◽  
O. Tervonen ◽  
J. Arokoski ◽  
...  

2021 ◽  
Author(s):  
Min Wu ◽  
Benyan Luo ◽  
Yamei Yu ◽  
Xiaoxia Li ◽  
Jian Gao ◽  
...  

Abstract Disorders of consciousness (DOC) are often accompanied by aberrant oscillatory neural activity in the thalamus and cerebral cortex. Patient-friendly non-invasive treatments targeting this functional anomaly are still missing. We propose and validate a novel approach that aims to restore DOC patients’ thalamocortical oscillations by combining rhythmic trigeminal-nerve stimulation (TNS) with comodulated musical stimulation. In a cluster-randomized, placebo-controlled, double-blinded, pretest-posttest clinical study, we show that application of this multisensory approach for 40 min on five consecutive days reliably leads to long-lasting improvements in DOC patients’ consciousness (assessed with Coma Recovery Scale-Revised) and oscillatory brain activity at the musical-electric TNS frequency (assessed with electroencephalography and a novel rhythmic auditory-speech paradigm). We found diagnostic improvement in 47% of patients in minimally conscious state and a positive relationship between patients’ behavioral and neural improvements. Based on this evidence we argue that non-invasive musical-electric TNS may serve as an effective patient-friendly DOC treatment and suggest frequency-specific oscillatory neural enhancement as its mode of action.


Gamification ◽  
2015 ◽  
pp. 83-112 ◽  
Author(s):  
Manuel Ninaus ◽  
Matthias Witte ◽  
Silvia E. Kober ◽  
Elisabeth V. C. Friedrich ◽  
Jürgen Kurzmann ◽  
...  

Neuroscience as well as computer gaming have rapidly advanced in the last decades. Yet, the combination of both fields is still in its infancy. One example of an emerging alliance is neurofeedback, where participants are required to learn controlling their own brain activity. So far, this kind of training is mostly applied in therapeutic settings, for example improving symptoms in epilepsy, attention-deficit/hyperactivity disorder, or autism spectrum disorder. However, there are some promising approaches that used neurofeedback in everyday situations for healthy subjects. This may prove especially valuable for serious games that aim to improve learning capabilities and cognitive aspects of individual users. The following chapter introduces the basic concepts and standards of neurofeedback. The different non-invasive imaging techniques are introduced along with successful applications in neurofeedback. Finally, benefits and pitfalls for future combinations of neurofeedback and games are discussed: while the former may profit from realistic and motivating video scenarios, the latter is expected to be a tool for evaluating and monitoring the direct effects on the user's brain.


2019 ◽  
Vol 24 (4) ◽  
pp. 98
Author(s):  
Cristina Campi ◽  
Annalisa Pascarella ◽  
Francesca Pitolli

Magnetoencephalography (MEG) aims at reconstructing the unknown neuroelectric activity in the brain from non-invasive measurements of the magnetic field induced by neural sources. The solution of this ill-posed, ill-conditioned inverse problem is usually dealt with using regularization techniques that are often time-consuming, and computationally and memory storage demanding. In this paper we analyze how a slimmer procedure, random sampling, affects the estimation of the brain activity generated by both synthetic and real sources.


2018 ◽  
Vol 13 (6) ◽  
pp. 57 ◽  
Author(s):  
Keltoum Chahour ◽  
Rajae Aboulaich ◽  
Abderrahmane Habbal ◽  
Cherif Abdelkhirane ◽  
Nejib Zemzemi

The fractional flow reserve (FFR) provides an efficient quantitative assessment of the severity of a coronary lesion. Our aim is to address the problem of computing non-invasive virtual fractional flow reserve (VFFR). In this paper, we present a preliminary study of the main features of flow over a stenosed coronary arterial portion, in order to enumerate the different factors affecting the VFFR. We adopt a non-Newtonian flow model and we assume that the two-dimensional (2D) domain is rigid in a first place. In a second place, we consider a simplified weakly coupled FSI model in order to take into account the infinitesimal displacements of the upper wall. A 2D finite element solver was implemented using Freefem++. We computed the VFFR profiles with respect to different lesion parameters and compared the results given by the rigid wall model to those obtained for the elastic wall one.


2014 ◽  
Vol 35 (7) ◽  
pp. 1493-1508 ◽  
Author(s):  
Nathan J Stevenson ◽  
Kirsi Palmu ◽  
Sverre Wikström ◽  
Lena Hellström-Westas ◽  
Sampsa Vanhatalo

1986 ◽  
Vol 14 (1) ◽  
pp. 32-36 ◽  
Author(s):  
A. B. Baker ◽  
A. J. Roxburgh

A prospective study was undertaken in twenty patients undergoing carotid endarterectomy using computerised EEG monitoring in the form of a density-modulated spectral array, spectral edge frequency and integrated EEG power for monitoring cerebral ischaemia. This form of monitoring proved to be easy to use and understand. Because ischaemic EEG events longer than one minute were not necessarily followed by postoperative deficits, the definition of significant events that would cause ischaemia may need to be modified.


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