scholarly journals Efficacy of Iopamidol for Sealing an Injured Thoracic Duct: Pilot Experiments in a Large Animal

2020 ◽  
Vol 10 (23) ◽  
pp. 8424
Author(s):  
Hyo Yeong Ahn ◽  
Seunghwan Song ◽  
Up Huh ◽  
Il Jae Wang ◽  
Jung Seop Eom ◽  
...  
Keyword(s):  
Thoracic Duct ◽  
Drug Effects ◽  
P Value ◽  
Large Animal ◽  
Systemic Embolization ◽  
Significant Difference ◽  
Chylous Leakage ◽  
Group A ◽  
Group B

Chylothorax can be spontaneously healed by lymphangiography using lipiodol, but pulmonary or systemic embolization is a potential complication. We determined the efficacy of iopamidol for treating chylous leakage in an animal model. Twelve pigs were randomly divided into two groups. After inducing thoracic duct damage, pigs from groups A and B were injected with iopamidol and lipiodol, respectively. At 5, 10, and 30 min after damage induction, the drug effects were monitored by video-assisted thoracoscopy and lymphangiography. In vitro, chyle samples from the pigs were incubated with iopamidol and lipiodol. The damaged thoracic duct was harvested and examined using microscopy. In group A, four and two pigs did not show chylous leakage after 5 and 10 min, respectively. In group B, none showed chylous leakage after 5 min. Nevertheless, the p value was 0.46, and there was no statistically significant difference between groups A and B. In vitro, both iopamidol- and lipiodol-treated chyle samples adhered after 5 min and solidified at 30 min. Our findings confirmed that the damaged thoracic duct was clogged with an amorphous proteinaceous material (iopamidol). Therefore, iopamidol is potentially a new therapeutic agent for chylous leakage. Thoracic duct embolization failures or systemic embolization risks from lipiodol injection may be avoided by injecting iopamidol via the thoracic duct, and this warrants further investigation.

scholarly journals Frictional Characteristics of the Newer Low-friction Elastomeric Ligatures

2016 ◽  
Vol 6 (1) ◽  
pp. 19-23
Author(s):  
Amol Mhatre ◽  
VK Ravindranath ◽  
Sachin Doshi ◽  
Girish Karandikar ◽  
PS Vivek
Keyword(s):  
Testing Machine ◽  
Frictional Resistance ◽  
Minimal Amount ◽  
New Delhi ◽  
Low Friction ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
New Generation

ABSTRACT Aim The aim of this in vitro study was to investigate the efficiency of the new generation of elastomeric ligatures with innovative designs (SlideTM and AlastiKTM Easy-to-Tie) in reducing frictional resistance (FR) during sliding mechanics as compared with conventional ligatures. Materials and Methods Sixty ligature samples divided into four groups were used for the study. Group A: QuiK-StiK™ (3M Unitek, Monrovia, CA, USA), Group B: AlastiK™ Easy-to-Tie (3M Unitek, Monrovia, CA, USA), Group C: Slide™ (Leone, Firenze, Italy), and Group D: SS ligatures 0.010” (Libral Traders, New Delhi, India). Universal Testing Machine, Instron was used for measuring FR at the bracket-wire interface. Results There was statistically significant difference in FR among all the four groups of ligatures tested (p < 0.001). Slide ligatures produced the least amount of FR followed by SS ligatures, Easy-to-Tie, and QuiK-StiK in the increasing order of the FR values registered. Conclusion SlideTM ligatures may represent a valid alternative to passive self-ligating brackets when minimal amount of friction is desired. Angulation introduced into the elastomeric ligatures reduces the friction in comparison to conventional elastomeric ligatures. How to cite this article Vivek PS, Ravindranath VK, Karandikar G, Doshi S, Mhatre A, Sonawane M. Frictional Characteristics of the Newer Low-friction Elastomeric Ligatures. J Contemp Dent 2016;6(1):19-23.

scholarly journals Comparison between scalpel incision and electrocautery incision in midline abdominal surgery: a comparative study

2021 ◽  
Vol 8 (5) ◽  
pp. 1507
Author(s):  
Amit Yadav ◽  
Lakshman Agarwal ◽  
Sumit A. Jain ◽  
Sanjay Kumawat ◽  
Sandeep Sharma
Keyword(s):  
Postoperative Pain ◽  
Blood Loss ◽  
Abdominal Surgery ◽  
Wound Infection ◽  
Skin Incision ◽  
P Value ◽  
Wound Area ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Fear of poor wound healing have curtailed the use of diathermy for making skin incision. Scalpel produces little damage to surrounding tissue but causing more blood loss. Our aim of study was to compare electrocautery incision with scalpel incision in terms of incision time, blood loss, postoperative pain and wound infection.Methods: Total of 104 patients were included in the study undergoing midline abdominal surgery. Patients were randomized into electrocautery (group A) and scalpel (group B). The incision dimension, incision time and blood loss were noted intraoperatively. Postoperative pain was noted on postoperative day 2 using visual analog scale. Wound complications were recorded on every postoperative day till the patient was discharged.Results: 52 patients in each of the two groups were analyzed. There was significant difference found between group A and group B in terms of mean incision time per unit wound area, 8.16±1.59 s\cm2 and 11.02±1.72 s\cm2 respectively (p value=0.0001). The mean blood loss per unit wound area was found to be significantly lower in group A (0.31±0.04 ml\cm2) as compared to group B (1.21±0.21), p value=0.0001. There was no significant difference noted in terms of postoperative pain and wound infection between both groups.Conclusions: Electrocautery can be considered safe in making skin incision in midline laparotomy compared to scalpel incision with comparable postoperative pain and wound infection with less intraoperative blood loss and less time consuming.

scholarly journals Comparison of Recovery Time of Propofol and Midazolam with Propofol Alone for Sedation in Endoscopic Retrograde Cholangiopancreatography

2021 ◽  
Vol 15 (5) ◽  
pp. 1024-1027
Author(s):  
Asma Samreen ◽  
Aamir Waseem ◽  
Muhammad Azam ◽  
Itrat Hussain Kazmi ◽  
Aamir Bashir ◽  
...  
Keyword(s):  
Endoscopic Retrograde Cholangiopancreatography ◽  
Recovery Time ◽  
Controlled Trial ◽  
P Value ◽  
Time Data ◽  
Endoscopic Retrograde ◽  
Intravenous Anesthetic ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Procedural sedation is required for multiple short duration procedures outside of the operating rooms especially in radiology and endoscopy suites. Intravenous anesthetic agent with rapid recovery profile is desirable in such circumstances. This study aims to compare two regimens of intravenous anesthetic agents. Aim: To compare the mean recovery time of propofol and midazolam with propofol alone for sedation in endoscopic retrograde cholangiopancreatography. Study Design: Randomized controlled trial. Settings: Department of Anesthesia, Shalamar Hospital, Lahore. Study Duration: June 2017 to December 2017. Methods: A total of 70 adult patients aged 20-60 years undergoing ERCP under sedation were included. Patients were given a combination of propofol and midazolam in group A while propofol alone was given in group B. After procedure, pts were transferred to recovery room and were followed for assessment of recovery time. Data were analyzed in SPSS vr 21, Independent t-test was applied & p-value ≤0.05 was considered statistically significant. Results: Significant difference was found in mean recovery time amongst both the groups. Mean recovery time in Group A (propofol and midazolam) was 19.29±4.50 minutes while in Group B (propofol alone) was 26.66±3.70 minutes showing statistically significant result with p-value = 0.0001. Conclusion: We conclude that mean recovery time with propofol plus midazolam is shorter as compared to propofol alone for sedation in ERCP. Keywords: Propofol, midazolam, sedation outside operation theatre.

Combination Therapy Of Tadalafil And Pentoxifylline In Severe Erectile Dysfunction; A Prospective Randomized Trial

2015 ◽  
Vol 87 (8) ◽  
Author(s):  
Santosh Kumar ◽  
Rajesh Roat ◽  
Swati Agrawal ◽  
Kumar Jayant ◽  
Ravimohan S. Mavuduru ◽  
...  
Keyword(s):  
Erectile Dysfunction ◽  
Combination Therapy ◽  
Erectile Function ◽  
T Test ◽  
P Value ◽  
Chi Square ◽  
Significant Difference ◽  
Chi Square Test ◽  
Group A ◽  
Group B

Abstractwas to assess efficacy of Tadalafil alone versus Tadalafil plus Pentoxifylline in the treatment of erectile dysfunction by using self administered IIEF-5 questionnaire.Two hundred and thirty seven patients presenting with ED at andrology OPD were evaluated for ED by a self administered IIEF (International Index of Erectile Function) questionnaire. Patients were systematically randomized by computer generated random table into two groups groups namely, group A: Tadalafil only group, group B: combination of Tadalafil + Pentoxifyl-line. All the patients were re-assessed by IIEF-5 questionnaire after 8 weeks of medical therapy. Statistical analysis was performed using student’s unpaired t-test, paired t-test, chi square test. p-value < 0.05 was considered statistically significant.Two hundred and thirty seven patients were included in the present study, in group A: 92 patients (78.6%) showed improvement in their IIEF score after 8 weeks of tadalafil treatment. While in group B, overall 104 patients(86.6%) showed improvement after combination of Tadalafil and Pentoxifylline. There was a statistically significant difference of percentage change in IIEF score was seen in group B (group A 90.7±15.2%, group B 95.6±13.4%; p value – 0.014). We found this difference even more statistically significant in patients with severe ED (group A 72.7±47.2%, group B 132.3±54.3%; p value – 0.000). There was no significant difference in between the two groups with regards to occur-rence of side effects.Both tadalafil and combination of Tadalafil + Pentoxifylline improve erectile function in patients of ED. Patients with severe ED showed much significant improvement in erectile function with combination therapy.

scholarly journals To Evaluate the Marginal Fit of Metal Copings Fabricated by Conventional Casting Procedure and Direct Metal Laser Sintering Technology – an In Vitro Study

2017 ◽  
Vol 05 (01) ◽  
pp. 039-046 ◽  
Author(s):  
Monica Sharma ◽  
Ajay Bansal ◽  
Sunny Panthi ◽  
Shefali Malik ◽  
Atulya Sharma
Keyword(s):  
Glass Ionomer Cement ◽  
In Vitro Study ◽  
Laser Sintering ◽  
Vitro Study ◽  
Direct Metal Laser Sintering ◽  
Marginal Fit ◽  
Significant Difference ◽  
Group A ◽  
Group B

Abstract Purpose: The purpose of this in vitro study was to evaluate marginal fit of cobalt- chromium (Co-Cr) copings fabricated by direct metal laser sintering system (DMLS) and conventional lost-wax technique (LW). Materials and method: Forty tooth preparations were carried out over extracted mandibular molars. They were divided into two groups A and B of 20 each. For group A Co-Cr copings were fabricated by direct metal laser sintering (DMLS) and for group B by lost wax technique (LW). Glass –ionomer cement (GIC) was used to tack the copings over their preparations. Marginal fit was then evaluated directly under the stereomicroscope. Results: The mean marginal gap of group A was 27.9 ± 2.4 μm and group B was 40.4 ±6 μm. Statistical analysis using t - test showed highly significant difference (P>.05) between the marginal mean of the DMLS (group A) compared to LW (group B). Conclusion: The DMLS copings demonstrated superior marginal fit compared to that of conventional Co-Cr casted copings.

scholarly journals Evaluation of the Effect of Water on Three Different Light Cured Composite Restorative Materials Stored in Water: An In Vitro Study

2012 ◽  
Vol 2012 ◽  
pp. 1-5 ◽  
Author(s):  
Basawaraj Biradar ◽  
Sudharani Biradar ◽  
Arvind MS
Keyword(s):  
Water Absorption ◽  
Physical And Mechanical Properties ◽  
In Vitro Study ◽  
Vitro Study ◽  
Weight Changes ◽  
Significant Difference ◽  
Restorative Materials ◽  
Group A ◽  
Group B

Objectives. The objective of this in vitro study was to investigate whether weight gain or loss in the three different composites occurs due to water absorption when they are stored in water.Methods. The composite restorative materials selected for this study included a microfine hybrid (Synergy) and two nanofilled composite restorative materials (Ceram X and Filtek Supreme Ultra). Twenty specimens of each material were fabricated of each composite material. Group A: Filtek Supreme Ultra, Group B: Synergy, Group C: Ceram X. Then all the specimens were stored in 10 ml Distilled water containing test tubes and placed in incubator at 37°C for six weeks. The weight changes of these specimens were measured daily for the first week and later once a week for next five weeks by using an electrical analytical balance.Results.The data was analyzed by one-way analysis of variance and Student'sttest. All groups showed maximum amount of water absorption in the first week than gradual decrease in the water absorption from the second to the sixth week, as compared to the first week and there is no statistically significant difference between the groups tested.Conclusion. All the composite restorative material absorbs some amount of water. The water absorption of the composite may decrease the physical and mechanical properties of the composites; hence it is necessary to consider the type of the material before starting the treatment.

Influence of prophylaxis on the microleakage of sealants: in vitro study

2002 ◽  
Vol 26 (4) ◽  
pp. 371-375 ◽  
Author(s):  
Ana Beatriz Alonso Chevitarese ◽  
Orlando Chevitarese ◽  
Ivete Pomarico Ribeiro de Souza ◽  
Roberto Braga de Carvalho Vianna
Keyword(s):  
Electron Microscope ◽  
Scanning Electron Microscope ◽  
In Vitro Study ◽  
Optical Microscope ◽  
Vitro Study ◽  
Significant Difference ◽  
Group A ◽  
Group B ◽  
Scanning Electron

The aim of this study was to evaluate the influence of prophylaxis on the sealants microleakage in 30 premolars divided into: Group A, Group B and Group C. The teeth were analyzed using the optical microscope (OM) and at scanning electron microscope (SEM). There was a statitical significant difference among the groups regarding the presence of microleakage, but not with the presence of tags.

scholarly journals HYPERLIPIDEMIC PATIENTS;

2019 ◽  
Vol 26 (03) ◽  
Author(s):  
Marium Shoukat ◽  
Hijab Batool ◽  
Faiza Javaid
Keyword(s):  
Protective Role ◽  
Lipid Lowering ◽  
Atheromatous Plaque ◽  
P Value ◽  
Cross Sectional ◽  
Apo B ◽  
Time Period ◽  
Significant Difference ◽  
Group A ◽  
Group B

Objectives: Role of niacin in decreasing cardiovascular accidents by lowering the levels of Apo-B in hyperlipidemic patients. Background: In hyperlipidemia, there are high levels of atherogenic lipoproteins leading to higher risk of atherosclerotic cardiovascular events. Patients with dyslipidemia use statins as a mainstay of therapy over last many decades. Recent studies show that apolipoproteins play a major role in formation of atheromatous plaque, thus there is an urgent need to study the effects of lipid lowering medication on apolipoprotiens levels. Study Design: Cross sectional analytical study. Setting: Sheikh Zayed Hospital Lahore (Department of Biochemistry and Chemical Pathology). Period: 12 weeks from July to Sep 2014. Materials and Methods: Recently diagnosed hyperlipidemic patients (n=44) were selected for the study purpose and divided into two equal groups; A and B. Each group was given different medication. Group A took only statin while group B took a combination of statin and niacin. Blood samples were taken at the start of medication and then after completion of 12 week time period. Results: At the start of the treatment there was no significant difference in the Apo B cholesterol level between the two groups (p value 0.972). However, after the end of 12 week duration, there was a significant reduction in the Apo level of group B taking statin and niacin as compared to group A taking statin alone (p value 0.003). Conclusions: Niacin has cardio-protective role when used in combination with niacin.

scholarly journals Stenting versus Pharmacological Therapy in Treatment of Single Vessel Intermediate Culprit Lesion Stenosis in Acute St-Segment Elevation Myocardial Infarction

2020 ◽  
pp. 99-106
Author(s):  
Hazem K. Shalaby ◽  
Ayman Mohammed El Saied ◽  
Hanan Kasem ◽  
Mai Salama ◽  
Seham Fahmy Badr
Keyword(s):  
Myocardial Infarction ◽  
Pharmacological Treatment ◽  
P Value ◽  
Culprit Lesion ◽  
Acute Stemi ◽  
Single Vessel ◽  
St Segment ◽  
Significant Difference ◽  
Group A ◽  
Group B

Background: Primary percutaneous coronary intervention (PCI) with stent implantation has been the standard therapy in acute ST-segment elevation myocardial infarction (STEMI) patients. Compared with medical treatment alone, stent implanting can achieve larger lumen gain and helps to reduce the re-occlusion risk of the infarct-related artery. Purpose: The aim of this study was to compare the effectiveness of stenting of single vessel intermediate culprit lesion stenosis to pharmacological treatment alone in acute STEMI patients. Methods: This study was prospective comparative interventional case series. It included 60 patients admitted to coronary care unit of our University hospital with acute STEMI. All patients were subjected to detailed history taking, clinical examination, 12 leads ECG, echocardiography and cardiac catheterization and angiography (TIMI flow and corrected TIMI frame count (CTFC) was reported. Patients selected were those with intermediate culprit lesion (40-70%) single vessel stenosis. Patients were divided into 2 groups: Group A: 30 patients who underwent stenting of the culprit lesion in addition to standard pharmacological treatment. Group B: 30 patients who received pharmacological treatment and no stenting (Glycoprotein II b/IIIa inhibitor in addition to the standard pharmacological treatment). Patients were followed up for 12 months and major adverse cardiac events (MACE) were reported (death, myocardial infarction, coronary re-vascularization, stroke and hospitalization because of heart failure). Results: 63.3% of group A patients reported complete ST segment resolution versus 30% of group B (P=0.034). TIMI Flow showed statistically significant difference in group A compared to group B regarding (P value=0.005) Group A reported slow fast blood flow (CTFC<60) in 1 patient (3.3%) while in group B it was reported in 5 patients (16%). There was a statistically significant difference between the 2 groups regarding CTFC (P value=0.029). At 12 months follow up, MACE were reported in one patient of group A versus 4 patients of group B (P value >0.05). Conclusion: Stent implantation reported better immediate efficacy and safety results among acute STEMI patients with single vessel intermediate culprit lesion stenosis and favourable effects in reducing MACE.

scholarly journals A Comparative Study of 5.5mm Temporal Sclerocorneal Manual Small Incision Cataract Surgery Versus 5.5mm Temporal Clear Corneal Extended-incision Phacoemulsification with Implantation of a 5.25mm Rigid pmma Intraocular lens in the Bag

2019 ◽  
Vol 3 (2) ◽  
Keyword(s):  
Cataract Surgery ◽  
Controlled Study ◽  
P Value ◽  
Small Incision Cataract Surgery ◽  
Corneal Incision ◽  
Small Incision ◽  
Clear Corneal Incision ◽  
Significant Difference ◽  
Group A ◽  
Group B

Objective: Aim of the study is to Compare the astigmatism induced by a reduced temporal sclerocorneal tunnel incision manual small incision cataract surgery with an extended temporal clear corneal Phacoemulsification of similar width . Methods: A Prospective, randomised controlled study was carried out in 224 selected patients who were again divided into two groups - Group A (112 patients) and Group B (112 patients). Group A patients underwent temporal manual small incision cataract surgery with a 5.5 mm sclerocorneal incision and Group B underwent phacoemulsification by a 2.8 mm clear corneal temporal incision which was extended to 5.5 mm before IOL implantation. In both groups, a 5.25 mm rigid PMMA IOL was implanted in the bag. UCVA and BCVA of both group of patients was quantified and analyzed at 1 week and at 6 weeks Observation: It was seen that the mean surgically Induced astigmatism in group A (N=112) was 0.5625D , which was slightly lesser than that in Group B (N=112) which was 0.65D, although the p-value of 0.26 indicated that there was statistically no significant difference in visual outcomes between the two groups of patients. Here, a p-value of < 0.05 was considered statistically significant. Conclusion: In Skilled and Safe hands, refractive outcomes following performing a 5.5mm temporal sclerocorneal frown-incision manual small incision cataract surgery and a phacoemulsification procedure by a 2.8mm temporal clear corneal incision extended to 5.5mm for implanting a 5.25mm rigid PMMA IOL , are comparable.

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