scholarly journals Anti-Yeast Synergistic Effects and Mode of Action of Australian Native Plant Essential Oils

2021 ◽  
Vol 11 (22) ◽  
pp. 10670
Author(s):  
Fahad Alderees ◽  
Ram Mereddy ◽  
Stephen Were ◽  
Michael E. Netzel ◽  
Yasmina Sultanbawa
Keyword(s):  
Essential Oils ◽  
Bioactive Compounds ◽  
Mode Of Action ◽  
Synergistic Effects ◽  
Weak Acid ◽  
Ion Leakage ◽  
Native Plant ◽  
Cell Organelles ◽  
Plant Essential Oils ◽  
Australian Native Plant

Yeasts are the most common group of microorganisms responsible for spoilage of soft drinks and fruit juices due to their ability to withstand juice acidity and pasteurization temperatures and resist the action of weak-acid preservatives. Food industries are interested in the application of natural antimicrobial compounds as an alternative solution to the spoilage problem. This study attempts to investigate the effectiveness of three Australian native plant essential oils (EOs) Tasmanian pepper leaf (TPL), lemon myrtle (LM) and anise myrtle (AM) against weak-acid resistant yeasts, to identify their major bioactive compounds and to elucidate their anti-yeast mode of action. The minimum inhibitory concentration (MIC), minimum fungicidal concentration (MFC) and minimum bactericidal concentration (MBC) were assessed for EOs against weak-acid resistant yeasts (Candida albicans, Candida krusei, Dekkera anomala, Dekkera bruxellensis, Rhodotorula mucilaginosa, Saccharomyces cerevisiae, Schizosaccharomyces pombe, Zygosaccharomyces bailii and Zygosaccharomyces rouxii) and bacteria (Staphylococcus aureus and Escherichia coli). The EOs showed anti-yeast and antibacterial activity at concentrations ranging from 0.03–0.07 mg/mL and 0.22–0.42 mg/mL for TPL and 0.07–0.31 mg/mL and 0.83–1.67 mg/mL for LM, respectively. The EOs main bioactive compounds were identified as polygodial in TPL, citral (neral and geranial) in LM and anethole in AM. No changes in the MICs of the EOs were observed in the sorbitol osmotic protection assay but were found to be increased in the ergosterol binding assay after the addition of exogenous ergosterol. Damaging of the yeast cell membrane, channel formation, cell organelles and ion leakage could be identified as the mode of action of TPL and LM EOs. The studied Australian native plant EOs showed potential as natural antimicrobials that could be used in the beverage and food industry against the spoilage causing yeasts.

Recent updates on the chemistry, bioactivities, mode of action, and industrial applications of plant essential oils

2021 ◽  
Vol 110 ◽  
pp. 78-89
Author(s):  
Zhi-Jing Ni ◽  
Xin Wang ◽  
Yi Shen ◽  
Kiran Thakur ◽  
Jinzhi Han ◽  
...  
Keyword(s):  
Essential Oils ◽  
Mode Of Action ◽  
Industrial Applications ◽  
Plant Essential Oils

scholarly journals Synergistic effects of Salvia officinalis L. essential oils and antibiotics against methicillin-resistant Staphylococcus aureus

2015 ◽  
Vol 67 (3) ◽  
pp. 949-956 ◽  
Author(s):  
Marina Milenkovic ◽  
Dragana Bozic ◽  
Violeta Slavkovska ◽  
Branislava Lakusic
Keyword(s):  
Staphylococcus Aureus ◽  
Essential Oils ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Synergistic Effects ◽  
Antimicrobial Properties ◽  
Inhibitory Effect ◽  
Salvia Officinalis ◽  
Methicillin Resistant ◽  
Plant Essential Oils ◽  
Broth Microdilution Method

Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) due to the acquisition of resistance to current antimicrobials pose a serious challenge for therapy, and new measures to treat and prevent this infectious pathogen are of crucial importance. Plant essential oils (EOs) and their constituents are promising agents with antimicrobial properties. The aim of this study was to evaluate the antistaphylococcal effect of essential oils from Salvia officinalis using the broth-microdilution method. Essential oils of S. officinalis were isolated from the same individual, but at different life stages - young and old leaves. The effects of combinations of sub-inhibitory concentrations of oil and different antibiotics were evaluated by the checkerboard method. The results, expressed as the fractional inhibitory concentration (FIC) and index (FICI), indicate that the essential oil isolated from young leaves potentiated the inhibitory effect of antibiotics against tested MRSA strains.

scholarly journals Antifungal and synergistic activity of five plant essential oils from Serbia against Trichoderma aggressivum f. europaeum Samuels & W. Gams

2020 ◽  
Vol 35 (3) ◽  
pp. 173-181
Author(s):  
Jelena Lukovic ◽  
Rada Djurovic-Pejcev ◽  
Tijana Djordjevic ◽  
Svetlana Milijasevic-Marcic ◽  
Natasa Duduk ◽  
...  
Keyword(s):  
Antifungal Activity ◽  
Essential Oils ◽  
Fungicidal Activity ◽  
Synergistic Effects ◽  
Mentha Piperita ◽  
Synergistic Activity ◽  
Mentha Spicata ◽  
Plant Essential Oils ◽  
Hypericum Perforatum L ◽  
Thymus Serpyllum

Five essential oils isolated from plants originating from Serbia and ten combinations of the selected essential oils were assayed to test their inhibitory and fungicidal activity against Trchoderma aggressivum f. europaeum Samuels & W. Gams using two distinctive methods: microdilution and fumigant macrodilution methods. The strongest activity was demonstrated by spearmint (Mentha spicata L.) and thyme (Thymus serpyllum L.) oils at the minimum inhibitory concentration (MIC) of 6.25 ?l ml-1 using microdilution, and 0.16 ?l ml-1 of air using fumigant macrodilution method. The antifungal activity of basil (Ocimum basilicum L.) and peppermint (Mentha piperita L.) was medium, while the oil extracted from St. John?s wort (Hypericum perforatum L.) exhibited the lowest activity. None of the selected essential oils exhibited fungicidal effect at minimal fungicidal concentrations (?FC) of over 25 ?l ml-1 or 0.32 ?l ml-1of air, using micro- and macrodilution, respectively. When microdilution was used, the strongest antifungal activity was demonstrated by two oil combinations: spearmint-thyme and spearmint-peppermint, having MIC and MFC values of 3.75 ?l ml-1. The lowest activity was demonstrated by the basil-St. John?s wort essential oil combination, at 30 ?l ml-1 MIC, and MFC exceeding 30 ?l ml-1. The obtained results indicate possible synergistic effects of essential oils and their components.

THE ACTIVITY OF ESSENTIAL OILS OBTAINED FROM SPECIES AND INTERSPECIES HYBRIDS OF THE Mentha GENUS AGAINST SELECTED PLANT PATHOGENIC BACTERIA

2018 ◽  
Vol 17 (6) ◽  
pp. 167-174 ◽  
Author(s):  
Małgorzata Schollenberger ◽  
Tomasz M. Staniek ◽  
Elżbieta Paduch-Cichal ◽  
Beata Dasiewicz ◽  
Agnieszka Gadomska-Gajadhur ◽  
...  
Keyword(s):  
Essential Oils ◽  
Pseudomonas Syringae ◽  
Pathogenic Bacteria ◽  
Antimicrobial Effect ◽  
Mentha Piperita ◽  
Mentha Spicata ◽  
Plant Essential Oils ◽  
Plant Pathogenic Bacteria ◽  
Interspecies Hybrids

Plant essential oils of six aromatic herb species and interspecies hybrids of the family Lamiaceae – chocolate mint (Mentha piperita × ‘Chocolate’), pineapple mint (Mentha suaveolens ‘Variegata’), apple mint (Mentha × rotundifolia), spearmint (Mentha spicata), orange mint (Mentha × piperita ‘Granada’) and strawberry mint (Mentha × villosa ‘Strawberry’) – were investigated for antimicrobial effects against plant pathogenic bacteria: Agrobacterium tumefaciens, Pseudomonas syringae pv. syringae and Xanthomonas arboricola pv. corylina. The screening was carried out in vitro on agar plates filled with the target organism. All essential oils screened exhibited a higher level of antibacterial activity against A. tumefaciens and X. arboricola pv. corylina than streptomycin used as a standard in all tests. The antimicrobial effect of streptomycin and five mint oils was at the same level for P. syringae pv. syringae. There were no significant differences in the influence of the chocolate mint oil on the growth inhibition of all bacteria tested. Plant essential oils from pineapple mint, apple mint, spearmint and strawberry mint showed the weakest antimicrobial activity against P. syringae pv. syringae and the strongest towards A. tumefaciens and X. arboricola pv. corylina. The essential oils from strawberry mint, pineapple mint, spearmint and apple mint had the strongest effect on A. tumefaciens, and the lowest inhibitory activity was exhibited by the chocolate mint and orange mint essential oils. X. arboricola pv. corylina was the most sensitive to the strawberry mint, pineapple mint and spearmint oils. The chocolate mint oil showed the greatest activity against P. syringae pv. syringae.

Extraction of Essential Oils from Medicinal Plants and their Utilization as Food Antioxidants

2020 ◽  
Vol 26 (5) ◽  
pp. 519-541 ◽  
Author(s):  
Giovanna Ferrentino ◽  
Ksenia Morozova ◽  
Christine Horn ◽  
Matteo Scampicchio
Keyword(s):  
Chemical Composition ◽  
Medicinal Plants ◽  
Beneficial Effect ◽  
Essential Oils ◽  
Bioactive Compounds ◽  
Antimicrobial Properties ◽  
Food Products ◽  
Human Diseases ◽  
Present Review ◽  
Green Technologies

Background: The use of essential oils is receiving increasing attention worldwide, as these oils are good sources of several bioactive compounds. Nowadays essential oils are preferred over synthetic preservatives thanks to their antioxidant and antimicrobial properties. Several studies highlight the beneficial effect of essential oils extracted from medicinal plants to cure human diseases such as hypertension, diabetes, or obesity. However, to preserve their bioactivity, the use of appropriate extraction technologies is required. Method: The present review aims to describe the studies published so far on the essential oils focusing on their sources and chemical composition, the technologies used for their recovery and their application as antioxidants in food products. Results: The review has been structured in three parts. In the first part, the main compounds present in essential oils extracted from medicinal plants have been listed and described. In the second part, the most important technologies used for extraction and distillation, have been presented. In detail, conventional methods have been described and compared with innovative and green technologies. Finally, in the last part, the studies related to the application of essential oils as antioxidants in food products have been reviewed and the main findings discussed in detail. Conclusions: In summary, an overview of the aforementioned subjects is presented by discussing the results of the most recent published studies.

Recent Nano-based Therapeutic Intervention of Bioactive Sesquiterpenes: Prospects in Cancer Therapeutics

2020 ◽  
Vol 26 (11) ◽  
pp. 1138-1144 ◽  
Author(s):  
Mohammad A. Ansari ◽  
Khan F. Badrealam ◽  
Asrar Alam ◽  
Saba Tufail ◽  
Gulshan Khalique ◽  
...  
Keyword(s):  
Physicochemical Properties ◽  
Essential Oils ◽  
Plant Species ◽  
Bioactive Compounds ◽  
Therapeutic Intervention ◽  
Cancer Therapeutics ◽  
Therapeutic Interventions ◽  
Pharmacological Intervention ◽  
Clinical Applicability ◽  
Near Future

: In the recent scenario, nanotechnology-based therapeutics intervention has gained tremendous impetus all across the globe. Nano-based pharmacological intervention of various bioactive compounds has been explored on an increasing scale. Sesquiterpenes are major constituents of essential oils (EOs) present in various plant species which possess intriguing therapeutic potentials. However, owing to their poor physicochemical properties; they have pharmacological limitations. Recent advances in nano-based therapeutic interventions offer various avenues to improve their therapeutic applicability. Reckoning with these, the present review collates various nano-based therapeutic intervention of sesquiterpenes with prospective potential against various debilitating diseases especially cancer. In our viewpoint, considering the burgeoning advancement in the field of nanomedicine; in the near future, the clinical applicability of these nano-formulated sesquiterpenes can be foreseen with great enthusiasm.

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