scholarly journals Automated Diagnosis of Childhood Pneumonia in Chest Radiographs Using Modified Densely Residual Bottleneck-Layer Features

2021 ◽  
Vol 11 (23) ◽  
pp. 11461
Author(s):  
Sinan Alkassar ◽  
Mohammed A. M. Abdullah ◽  
Bilal A. Jebur ◽  
Ghassan H. Abdul-Majeed ◽  
Bo Wei ◽  
...  
Keyword(s):  
Bacterial Infections ◽  
Spatial Information ◽  
Severe Infection ◽  
Learning Approaches ◽  
The Novel ◽  
New Approach ◽  
X Ray ◽  
Adaptive Weight ◽  
Chest X Ray ◽  
Residual Block

Pneumonia is a severe infection that affects the lungs due to viral or bacterial infections such as the novel COVID-19 virus resulting in mild to critical health conditions. One way to diagnose pneumonia is to screen prospective patient’s lungs using either a Computed Tomography (CT) scan or chest X-ray. To help radiologists in processing a large amount of data especially during pandemics, and to overcome some limitations in deep learning approaches, this paper introduces a new approach that utilizes a few light-weighted densely connected bottleneck residual block features to extract rich spatial information. Then, shrinking data batches into a single vector using four efficient methods. Next, an adaptive weight setup is proposed utilizing Adaboost ensemble learning which adaptively sets weight for each classifier depending on the scores generated to achieve the highest true positive rates while maintaining low negative rates. The proposed method is evaluated using the Kaggle chest X-ray public dataset and attained an accuracy of 99.6% showing superiority to other deep networks-based pneumonia diagnosis methods.

scholarly journals Objective Evaluation of Deep Uncertainty Predictions for COVID-19 Detection

2021 ◽  
Author(s):  
Hamzeh Asgharnezhad ◽  
Afshar Shamsi ◽  
Roohallah Alizadehsani ◽  
Abbas Khosravi ◽  
Saeid Nahavandi ◽  
...  
Keyword(s):  
Uncertainty Quantification ◽  
Performance Metrics ◽  
Confusion Matrix ◽  
Objective Evaluation ◽  
X Rays ◽  
The Novel ◽  
X Ray ◽  
Uncertainty Estimates ◽  
Chest X Ray ◽  
Novel Concept

Abstract Deep neural networks (DNNs) have been widely applied for detecting COVID-19 in medical images. Existing studies mainly apply transfer learning and other data representation strategies to generate accurate point estimates. The generalization power of these networks is always questionable due to being developed using small datasets and failing to report their predictive confidence. Quantifying uncertainties associated with DNN predictions is a prerequisite for their trusted deployment in medical settings. Here we apply and evaluate three uncertainty quantification techniques for COVID-19 detection using chest X-Ray (CXR) images. The novel concept of uncertainty confusion matrix is proposed and new performance metrics for the objective evaluation of uncertainty estimates are introduced. Through comprehensive experiments, it is shown that networks pertained on CXR images outperform networks pretrained on natural image datasets such as ImageNet. Qualitatively and quantitatively evaluations also reveal that the predictive uncertainty estimates are statistically higher for erroneous predictions than correct predictions. Accordingly, uncertainty quantification methods are capable of flagging risky predictions with high uncertainty estimates. We also observe that ensemble methods more reliably capture uncertainties during the inference. DNN-based solutions for COVID-19 detection have been mainly proposed without any principled mechanism for risk mitigation. Previous studies have mainly focused on on generating single-valued predictions using pretrained DNNs. In this paper, we comprehensively apply and comparatively evaluate three uncertainty quantification techniques for COVID-19 detection using chest X-Ray images. The novel concept of uncertainty confusion matrix is proposed and new performance metrics for the objective evaluation of uncertainty estimates are introduced for the first time. Using these new uncertainty performance metrics, we quantitatively demonstrate where and when we could trust DNN predictions for COVID-19 detection from chest X-rays. It is important to note the proposed novel uncertainty evaluation metrics are generic and could be applied for evaluation of probabilistic forecasts in all classification problems.

scholarly journals An Efficient Deep Learning Approach to Pneumonia Classification in Healthcare

2019 ◽  
Vol 2019 ◽  
pp. 1-7 ◽  
Author(s):  
Okeke Stephen ◽  
Mangal Sain ◽  
Uchenna Joseph Maduh ◽  
Do-Un Jeong
Keyword(s):  
Neural Network ◽  
Deep Learning ◽  
Convolutional Neural Network ◽  
Network Model ◽  
Neural Network Model ◽  
Data Augmentation ◽  
Classification Performance ◽  
Learning Approaches ◽  
X Ray ◽  
Chest X Ray

This study proposes a convolutional neural network model trained from scratch to classify and detect the presence of pneumonia from a collection of chest X-ray image samples. Unlike other methods that rely solely on transfer learning approaches or traditional handcrafted techniques to achieve a remarkable classification performance, we constructed a convolutional neural network model from scratch to extract features from a given chest X-ray image and classify it to determine if a person is infected with pneumonia. This model could help mitigate the reliability and interpretability challenges often faced when dealing with medical imagery. Unlike other deep learning classification tasks with sufficient image repository, it is difficult to obtain a large amount of pneumonia dataset for this classification task; therefore, we deployed several data augmentation algorithms to improve the validation and classification accuracy of the CNN model and achieved remarkable validation accuracy.

scholarly journals The use of lung ultrasound during the COVID-19 pandemic

2020 ◽  
Vol 27 (SP1) ◽  
pp. e64-e75
Author(s):  
Aly Youssef ◽  
Marta Cavalera ◽  
Carlotta Azzarone ◽  
Carla Serra ◽  
Elena Brunelli ◽  
...  
Keyword(s):  
Health System ◽  
Pulmonary Infection ◽  
Lung Ultrasound ◽  
The Novel ◽  
Chain Reaction ◽  
X Ray ◽  
Rapid Learning ◽  
Chest X Ray ◽  
Polymerase Chain ◽  
Novel Coronavirus

The novel coronavirus disease (COVID-19) is a challenge to every health system. Unfortunately, it is unlikely that this pandemic will disappear soon. No health system, with its present resources and workflow, is capable enough to deal with a full-blown wave of this pandemic. Acquisition of specific new skills may be fundamental in delivering appropriate health care for our patients. The gold standard for diagnosis of the COVID-19 infection is real-time reverse transcription polymerase chain reaction. Radiological investigations (chest X-ray or high-resolution computerized tomography [CT]) can be helpful both for diagnosis and management, but they have many limitations. Ultrasound has been suggested as a reliable and accurate tool for assessing the lungs in COVID-19 patients. Lung ultrasound (LUS) can show specific signs of inter-stitial pneumonia, which is characteristic of COVID-19 pulmonary infection. In addition, nonradiologist specialists with experience in ultrasound can be trained on LUS with a relatively rapid learning curve. In pregnancy, LUS can be particularly useful due to the avoidance of exposure to ionizing radiation. In this review, we present the advantages, techniques, and limitations of the use of LUS during the COVID-19 pandemic, with specific focus on pregnancy.

scholarly journals Deep Learning Approaches for Detecting COVID-19 From Chest X-Ray Images: A Survey

IEEE Access ◽  
2021 ◽  
Vol 9 ◽  
pp. 20235-20254
Author(s):  
Hanan S. Alghamdi ◽  
Ghada Amoudi ◽  
Salma Elhag ◽  
Kawther Saeedi ◽  
Jomanah Nasser
Keyword(s):  
Deep Learning ◽  
Learning Approaches ◽  
X Ray ◽  
Chest X Ray

scholarly journals Multiobjective Genetic Algorithm and Convolutional Neural Network Based COVID-19 Identification in Chest X-Ray Images

2021 ◽  
Vol 2021 ◽  
pp. 1-9
Author(s):  
Prashant Kumar Shukla ◽  
Jasminder Kaur Sandhu ◽  
Anamika Ahirwar ◽  
Deepika Ghai ◽  
Priti Maheshwary ◽  
...  
Keyword(s):  
Genetic Algorithm ◽  
Diagnostic Testing ◽  
The Novel ◽  
Screening Process ◽  
X Ray ◽  
Multiobjective Genetic Algorithm ◽  
Global Pandemic ◽  
Chest X Ray ◽  
Novel Coronavirus ◽  
Fold Cross Validation

COVID-19 is a new disease, caused by the novel coronavirus SARS-CoV-2, that was firstly delineated in humans in 2019.Coronaviruses cause a range of illness in patients varying from common cold to advanced respiratory syndromes such as Severe Acute Respiratory Syndrome (SARS-CoV) and Middle East Respiratory Syndrome (MERS-CoV). The SARS-CoV-2 outbreak has resulted in a global pandemic, and its transmission is increasing at a rapid rate. Diagnostic testing and approaches provide a valuable tool for doctors and support them with the screening process. Automatic COVID-19 identification in chest X-ray images can be useful to test for COVID-19 infection at a good speed. Therefore, in this paper, a framework is designed by using Convolutional Neural Networks (CNN) to diagnose COVID-19 patients using chest X-ray images. A pretrained GoogLeNet is utilized for implementing the transfer learning (i.e., by replacing some sets of final network CNN layers). 20-fold cross-validation is considered to overcome the overfitting quandary. Finally, the multiobjective genetic algorithm is considered to tune the hyperparameters of the proposed COVID-19 identification in chest X-ray images. Extensive experiments show that the proposed COVID-19 identification model obtains remarkably better results and may be utilized for real-time testing of patients.

scholarly journals Nuances of Interpreting X-ray Analysis by Deep Learning and Lessons for Reporting Experimental Findings

Sci ◽  
2022 ◽  
Vol 4 (1) ◽  
pp. 3
Author(s):  
Steinar Valsson ◽  
Ognjen Arandjelović
Keyword(s):  
Machine Learning ◽  
Deep Learning ◽  
Spatial Information ◽  
Characteristic Curve ◽  
Image Data ◽  
Qualitative Assessment ◽  
Learning Approaches ◽  
Clinical Value ◽  
Diagnostic Significance ◽  
X Ray

With the increase in the availability of annotated X-ray image data, there has been an accompanying and consequent increase in research on machine-learning-based, and ion particular deep-learning-based, X-ray image analysis. A major problem with this body of work lies in how newly proposed algorithms are evaluated. Usually, comparative analysis is reduced to the presentation of a single metric, often the area under the receiver operating characteristic curve (AUROC), which does not provide much clinical value or insight and thus fails to communicate the applicability of proposed models. In the present paper, we address this limitation of previous work by presenting a thorough analysis of a state-of-the-art learning approach and hence illuminate various weaknesses of similar algorithms in the literature, which have not yet been fully acknowledged and appreciated. Our analysis was performed on the ChestX-ray14 dataset, which has 14 lung disease labels and metainfo such as patient age, gender, and the relative X-ray direction. We examined the diagnostic significance of different metrics used in the literature including those proposed by the International Medical Device Regulators Forum, and present the qualitative assessment of the spatial information learned by the model. We show that models that have very similar AUROCs can exhibit widely differing clinical applicability. As a result, our work demonstrates the importance of detailed reporting and analysis of the performance of machine-learning approaches in this field, which is crucial both for progress in the field and the adoption of such models in practice.

scholarly journals Fast Deep Learning Computer-Aided Diagnosis against the Novel COVID-19 pandemic from Digital Chest X-ray Images

2020 ◽  
Author(s):  
Mugahed A. Al-antari ◽  
Cam-Hao Hua ◽  
Sungyoung Lee
Keyword(s):  
Deep Learning ◽  
Lung Disease ◽  
Lung Diseases ◽  
Diagnostic Performance ◽  
The Novel ◽  
X Ray ◽  
Cad System ◽  
Computer Aided ◽  
Chest X Ray ◽  
Aided Diagnosis

Abstract Background and Objective: The novel coronavirus 2019 (COVID-19) is a harmful lung disease that rapidly attacks people worldwide. At the end of 2019, COVID-19 was discovered as mysterious lung disease in Wuhan, Hubei province of China. World health organization (WHO) declared the coronavirus outbreak a pandemic in the second week of March 2020. Simultaneous deep learning detection and classification of COVID-19 from the entire digital X-ray images is the key to efficiently assist patients and physicians for a fast and accurate diagnosis.Methods: In this paper, a deep learning computer-aided diagnosis (CAD) based on the YOLO predictor is proposed to simultaneously detect and diagnose COVID-19 among the other eight lung diseases: Atelectasis, Infiltration, Pneumothorax, Mass, Effusion, Pneumonia, Cardiomegaly, and Nodule. The proposed CAD system is assessed via five-fold tests for multi-class prediction problem using two different databases of chest X-ray images: COVID-19 and ChestX-ray8. The proposed CAD system is trained using an annotated training set of 50,490 chest X-ray images.Results: The suspicious regions of COVID-19 from the entire X-ray images are simultaneously detected and classified end-to-end via the proposed CAD predictor achieving overall detection and classification accuracies of 96.31% and 97.40%, respectively. The most testing images of COVID-19 and other lunge diseases are correctly predicted achieving intersection over union (IoU) with their GTs greater than 90%. Applying deep learning regularizers of data balancing and augmentation improve the diagnostic performance by 6.64% and 12.17% in terms of overall accuracy and F1-score, respectively. Meanwhile, the proposed CAD system presents its feasibility to diagnose the individual chest X-ray image within 0.009 second. Thus, the presented CAD system could predict 108 frames/second (FPS) at the real-time of prediction.Conclusion: The proposed deep learning CAD system shows its capability and reliability to achieve promising COVID-19 diagnostic performance among all other lung diseases. The proposed deep learning model seems reliable to assist health care systems, patients, and physicians in their practical validations.

scholarly journals A Review on Deep Learning Approaches for COVID-19 Detection in Chest X-Ray Images

2021 ◽  
Vol 9 (10) ◽  
pp. 1792-1801
Author(s):  
Tanishka Dodiya
Keyword(s):  
Deep Learning ◽  
Detection System ◽  
High Rate ◽  
Learning Approaches ◽  
X Ray ◽  
First Case ◽  
X Ray Imaging ◽  
The World ◽  
Chest X Ray ◽  
Diagnostic Capabilities

Abstract: COVID-19 also famously known as Coronavirus is one of the deadliest viruses found in the world, which has a high rate in both demise and spread. This has caused a severe pandemic in the world. The virus was first reported in Wuhan, China, registering causes like pneumonia. The first case was encountered on December 31, 2019. As of 20th October 2021, more than 242 million cases have been reported in more than 188 countries, and it has around 5 million deaths. COVID- 19 infected persons have pneumonia-like symptoms, and the infection damages the body's respiratory organs, making breathing difficult. The elemental clinical equipment as of now being employed for the analysis of COVID-19 is RT-PCR, which is costly, touchy, and requires specific clinical workforce. According to recent studies, chest X-ray scans include important information about the start of the infection, and this information may be examined so that diagnosis and treatment can begin sooner. This is where artificial intelligence meets the diagnostic capabilities of intimate clinicians. X-ray imaging is an effectively available apparatus that can be an astounding option in the COVID-19 diagnosis. The architecture usually used are VGG16, ResNet50, DenseNet121, Xception, ResNet18, etc. This deep learning based COVID detection system can be installed in hospitals for early diagnosis, or it can be used as a second opinion. Keywords: COVID-19, Deep Learning, CNN, CT-Image, Transfer Learning, VGG, ResNet, DenseNet

scholarly journals COVID-19 detection in Chest X-ray Images using Deep Learning

2020 ◽  
Author(s):  
Ebru Erdem ◽  
Tolga Aydın
Keyword(s):  
Deep Learning ◽  
Deep Neural Networks ◽  
Empirical Evaluation ◽  
Specific Information ◽  
The Novel ◽  
X Ray ◽  
Chest X Ray ◽  
Lung Infections ◽  
Day By Day

Abstract COVID-19 is an important threat worldwide. This disease is caused by the novel SARS-CoV-2. CXR and CT images reveal specific information about the disease. However, when interpreting these images, experiencing an overlap with other lung infections complicates the detection of the disease. Due to this situation, the need for computer-aided systems is increasing day by day. In this study, solutions were developed with proposed models based on deep neural networks (DNN). All the analyses were performed on a publicly available CXR dataset. This study offers a comparison of the deep learning models (SqueezeNet, Inception-V3, VGG16, MobileNet, Xception, VGG19+MobileNet (Concatenated)) that results in the detection and classification of a disease. Empirical evaluation demonstrates that the Inception-V3 model gives 90% accuracy with 100% precision for the COVID-19 infection. This model has been provided with better results compared to other models. In addition to the studies in the literature, it has been observed that the proposed pre-trained-based concatenated model gives very similar successful results to the other models.

scholarly journals Deep convolutional approaches for the analysis of Covid-19 using chest X-Ray images from portable devices

2020 ◽  
Author(s):  
Joaquim de Moura ◽  
Lucía Ramos ◽  
Plácido L. Vidal ◽  
Milena Cruz ◽  
Laura Abelairas ◽  
...  
Keyword(s):  
Network Architecture ◽  
Clinical Decision Making ◽  
Clinical Decision ◽  
World Health ◽  
Portable Devices ◽  
Learning Approaches ◽  
Portable Equipment ◽  
Convolutional Network ◽  
X Ray ◽  
Chest X Ray

The recent human coronavirus disease (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been declared as a global pandemic on 11 March 2020 by the World Health Organization. Given the effects of COVID-19 in pulmonary tissues, chest radiography imaging plays an important role for the screening, early detection and monitoring of the suspected individuals. Hence, as the pandemic of COVID-19 progresses, there will be a greater reliance on the use of portable equipment for the acquisition of chest X-Ray images due to its accessibility, widespread availability and benefits regarding to infection control issues, minimizing the risk of cross contamination. This work presents novel fully automatic approaches specifically tailored for the classification of chest X-Ray images acquired by portable equipment into 3 different clinical categories: normal, pathological and COVID-19. For this purpose, two complementary deep learning approaches based on a densely convolutional network architecture are herein presented. The joint response of both approaches allows to enhance the differentiation between patients infected with COVID-19, patients with other diseases that manifest characteristics similar to COVID-19 and normal cases. The proposed approaches were validated over a dataset provided by the Radiology Service of the Complexo Hospitalario Universitario A Coruña (CHUAC) specifically retrieved for this research. Despite the poor quality of chest X-Ray images that is inherent to the nature of the portable equipment, the proposed approaches provided satisfactory results, allowing a reliable analysis of portable radiographs, to support the clinical decision-making process.

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