scholarly journals Heat Transfer in Biological Spherical Tissues during Hyperthermia of Magnetoma

Biology ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 1259
Author(s):  
Mahmoud Ragab ◽  
Ahmed E. Abouelregal ◽  
Huda F. AlShaibi ◽  
Rasha A. Mansouri
Keyword(s):  
Heat Transfer ◽  
Blood Perfusion ◽  
Biological Tissues ◽  
Numerical Results ◽  
Skin Tumor ◽  
Conduction Equation ◽  
Inverse Transformation ◽  
Suggested Model ◽  
Hyperthermia Treatment ◽  
Transformation Methods

Hyperthermia therapy is now being used to treat cancer. However, understanding the pattern of temperature increase in biological tissues during hyperthermia treatment is essential. In recent years, many physicians and engineers have studied the use of computational and mathematical models of heat transfer in biological systems. The rapid progress in computing technology has intrigued many researchers. Many medical procedures also use engineering techniques and mathematical modeling to ensure their safety and assess the risks involved. One such model is the modified Pennes bioheat conduction equation. This paper provides an analytical solution to the modified Pennes bioheat conduction equation with a single relaxation time by incorporating in it the (MGT) equation. The suggested model examines heat transport in biological tissues as forming an infinite concentric spherical region during magnetic fluid hyperthermia. To investigate thermal reactions caused by temperature shock, specifically the influence of heat generation through heat treatment on a skin tumor [AEGP9], the Laplace transformation, and numerical inverse transformation methods are used. This model was able to explain the effects of different therapeutic approaches such as cryotherapy sessions, laser therapy, and physical occurrences, transfer, metabolism support, and blood perfusion. Comparison of the numerical results of the suggested model with those in the literature confirmed the validity of the model’s numerical results.

Nonclassical Heat Transfer Models for Laser-Induced Thermal Damage in Biological Tissues

2011 ◽  
Author(s):  
Jianhua Zhou ◽  
J. K. Chen ◽  
Yuwen Zhang
Keyword(s):  
Heat Transfer ◽  
Heat Flux ◽  
Heat Conduction ◽  
Temperature Gradient ◽  
Thermal Wave ◽  
Thermal Damage ◽  
Blood Perfusion ◽  
Biological Tissues ◽  
Phase Lag ◽  
Fourier Heat Conduction

To ensure personal safety and improve treatment efficiency in laser medical applications, one of the most important issues is to understand and accurately assess laser-induced thermal damage to biological tissues. Biological tissues generally consist of nonhomogeneous inner structures, in which heat flux equilibrates to the imposed temperature gradient via a thermal relaxation mechanism which cannot be explained by the traditional parabolic heat conduction model based on Fourier’s law. In this article, two non-Fourier heat conduction models, hyperbolic thermal wave model and dual-phase-lag (DPL) model, are formulated to describe the heat transfer in living biological tissues with blood perfusion and metabolic heat generation. It is shown that the non-Fourier bioheat conduction models could predict significantly different temperature and thermal damage in tissues from the traditional parabolic model. It is also found that the DPL bioheat conduction equations can be reduced to the Fourier heat conduction equations only if both phase lag times of the temperature gradient (τT) and the heat flux (τq) are zero. Effects of laser parameters and blood perfusion on the thermal damage simulated in tissues are also studied. The result shows that the overall effects of the blood flow on the thermal response and damage are similar to those of the time delay τT. The two-dimensional numerical results indicate that for a local heating with the heated spot being smaller than the tissue bulk, the variations of the non-uniform distributions of temperature suggest that the multi-dimensional effects of thermal wave and diffusion not be negligible.

scholarly journals Numerical Analysis of Breast Cancer Cell with Gold Nanoparticles Necrosis by Laser Hyperthermia

2020 ◽  
Vol 10 (2) ◽  
pp. 138-144
Author(s):  
Shna A. Karim ◽  
Yousif M. Hassan
Keyword(s):  
Breast Cancer ◽  
Heat Transfer ◽  
Gold Nanoparticles ◽  
Cancer Cells ◽  
Biological Tissues ◽  
Surrounding Tissue ◽  
Threshold Temperature ◽  
Cancer Tissue ◽  
Hyperthermia Treatment ◽  
Laser Hyperthermia

Laser hyperthermia treatment of cancer tissue is widely used in cancer treatment to destroy cancer cells. This study focus on the mechanisms of heat transfer in biological tissues to minimize damage to the tissues resulting from extra heat applied. The important feature of this method is heating of specific region to raise its temperature to a threshold temperature and destroying cancer cells without to destroy surrounding tissue. In this study, we have used the combinations of laser light and gold nanoparticles to investigate the influence of nanoparticles on the spatial distribution of temperature in the tumor and healthy tissues. Accurate simulations and solving Penne’s bio-heat transfer equation were used to solve and model the thermal tumor breast cancer in the presence of gold. Nanoparticles of some particular sizes and concentrations were selected. We would like here to stress that our attempt was a theoretical and computer model with some real and hypothesized parameters and homogeneous target. The results of this study help the doctors in the study for results of hyperthermia treatment before using it on the vivo by known the properties of the laser used and the properties of the breast tumor trying to reduce the damage of the treatment.

Numerical simulation of the effect of baffle cut and baffle spacing on shell side heat exchanger performance using CFD

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Swanand Gaikwad ◽  
Ashish Parmar
Keyword(s):  
Heat Transfer ◽  
Heat Transfer Coefficient ◽  
Heat Exchanger ◽  
Pressure Drop ◽  
Transfer Coefficient ◽  
Numerical Results ◽  
Shell Side ◽  
Tube Heat Exchanger ◽  
Shell And Tube ◽  
Two Parameters

AbstractHeat exchangers possess a significant role in energy transmission and energy generation in most industries. In this work, a three-dimensional simulation has been carried out of a shell and tube heat exchanger (STHX) consisting of segmental baffles. The investigation involves using the commercial code of ANSYS CFX, which incorporates the modeling, meshing, and usage of the Finite Element Method to yield numerical results. Much work is available in the literature regarding the effect of baffle cut and baffle spacing as two different entities, but some uncertainty pertains when we discuss the combination of these two parameters. This study aims to find an appropriate mix of baffle cut and baffle spacing for the efficient functioning of a shell and tube heat exchanger. Two parameters are tested: the baffle cuts at 30, 35, 40% of the shell-inside diameter, and the baffle spacing’s to fit 6,8,10 baffles within the heat exchanger. The numerical results showed the role of the studied parameters on the shell side heat transfer coefficient and the pressure drop in the shell and tube heat exchanger. The investigation shows an increase in the shell side heat transfer coefficient of 13.13% when going from 6 to 8 baffle configuration and a 23.10% acclivity for the change of six baffles to 10, for a specific baffle cut. Evidence also shows a rise in the pressure drop with an increase in the baffle spacing from the ranges of 44–46.79%, which can be controlled by managing the baffle cut provided.

scholarly journals Computational Performance of Disparate Lattice Boltzmann Scenarios under Unsteady Thermal Convection Flow and Heat Transfer Simulation

Computation ◽  
2021 ◽  
Vol 9 (6) ◽  
pp. 65
Author(s):  
Aditya Dewanto Hartono ◽  
Kyuro Sasaki ◽  
Yuichi Sugai ◽  
Ronald Nguele
Keyword(s):  
Heat Transfer ◽  
Steady State ◽  
Natural Convection ◽  
Lattice Boltzmann ◽  
Numerical Results ◽  
Convection And Heat Transfer ◽  
Steady State Condition ◽  
Physical Systems ◽  
Flow And Heat Transfer ◽  
Computational Performance

The present work highlights the capacity of disparate lattice Boltzmann strategies in simulating natural convection and heat transfer phenomena during the unsteady period of the flow. Within the framework of Bhatnagar-Gross-Krook collision operator, diverse lattice Boltzmann schemes emerged from two different embodiments of discrete Boltzmann expression and three distinct forcing models. Subsequently, computational performance of disparate lattice Boltzmann strategies was tested upon two different thermo-hydrodynamics configurations, namely the natural convection in a differentially-heated cavity and the Rayleigh-Bènard convection. For the purposes of exhibition and validation, the steady-state conditions of both physical systems were compared with the established numerical results from the classical computational techniques. Excellent agreements were observed for both thermo-hydrodynamics cases. Numerical results of both physical systems demonstrate the existence of considerable discrepancy in the computational characteristics of different lattice Boltzmann strategies during the unsteady period of the simulation. The corresponding disparity diminished gradually as the simulation proceeded towards a steady-state condition, where the computational profiles became almost equivalent. Variation in the discrete lattice Boltzmann expressions was identified as the primary factor that engenders the prevailed heterogeneity in the computational behaviour. Meanwhile, the contribution of distinct forcing models to the emergence of such diversity was found to be inconsequential. The findings of the present study contribute to the ventures to alleviate contemporary issues regarding proper selection of lattice Boltzmann schemes in modelling fluid flow and heat transfer phenomena.

Experimental and numerical investigations on a high-density polyethylene (HDPE) blown film cooling with a new design of the counter-flow/radial jet air-ring

2021 ◽  
pp. 875608792110260
Author(s):  
ME Ismail ◽  
MM Awad ◽  
AM Hamed ◽  
MY Abdelaal ◽  
EB Zeidan
Keyword(s):  
Heat Transfer ◽  
Numerical Simulations ◽  
Film Cooling ◽  
Radiation Heat Transfer ◽  
Absolute Error ◽  
Numerical Results ◽  
Upper Lip ◽  
Original Design ◽  
Blown Film ◽  
Set Up

This study experimentally and numerically investigates a typical HDPE blown film production process cooled via a single-lip air-ring. The processing observations are considered for the proposed subsequent modifications on the air-ring design and the location relative to the die to generate a radial jet, directly impinging on the bubble. Measurements are performed to collect the actual operating parameters to set up the numerical simulations. The radiation heat transfer and the polymer phase change are considered in the numerical simulations. The velocity profile at the air-ring upper-lip is measured via a five-hole Pitot tube to compare with the numerical results. The comparison between the measurements and the numerical results showed that the simulations with the STD [Formula: see text] turbulence model are more accurate with a minimum relative absolute error (RAE) of 1.6%. The numerical results indicate that the peak Heat Transfer Coefficient (HTC) at the impingement point for the modified design with radial jet and longer upper-lip is 29.1% higher than the original design at the same conditions. Besides, increasing the air-ring upper-lip height increased the averaged HTC, which is 13.4% higher than the original design.

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