Phytochemistry and Diverse Pharmacology of Genus Mimosa: A Review

The genus Mimosa belongs to the Fabaceae family and comprises almost 400 species of herbs, shrubs and ornamental trees. The genus Mimosa is found all over the tropics and subtropics of Asia, Africa, South America, North America and Australia. Traditionally, this genus has been popular for the treatment of jaundice, diarrhea, fever, toothache, wound healing, asthma, leprosy, vaginal and urinary complaints, skin diseases, piles, gastrointestinal disorders, small pox, hepatitis, tumor, HIV, ulcers and ringworm. The review covered literature available from 1959 to 2020 collected from books, scientific journals and electronic searches, such as Science Direct, Web of Science and Google scholar. Various keywords, such as Mimosa, secondary metabolites, medicines, phytochemicals and pharmacological values, were used for the data search. The Mimosa species are acknowledged to be an essential source of secondary metabolites with a wide-ranging biological functions, and up until now, 145 compounds have been isolated from this genus. Pharmacological studies showed that isolated compounds possess significant potential, such as antiprotozoal, antimicrobial, antiviral, antioxidant, and antiproliferative as well as cytotoxic activities. Alkaloids, chalcones, flavonoids, indoles, terpenes, terpenoids, saponins, steroids, amino acids, glycosides, flavanols, phenols, lignoids, polysaccharides, lignins, salts and fatty esters have been isolated from this genus. This review focused on the medicinal aspects of the Mimosa species and may provide a comprehensive understanding of the prospective of this genus as a foundation of medicine, supplement and nourishment. The plants of this genus could be a potential source of medicines in the near future.

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Bioprospecting Cryptogams as Potential Source of Unique Biodynamic Phytochemicals with Diverse Pharmaceutical Applications

Cryptogam Biodiversity and Assessment ◽

10.21756/cba.v1i1.10959 ◽

2016 ◽

Vol 1 (1) ◽

Author(s):

Brahma N. Singh ◽

Garima Pandey ◽

Prateeksha ◽

J. Kumar

Keyword(s):

Secondary Metabolites ◽

Higher Plants ◽

New Drugs ◽

Terrestrial Plants ◽

Pharmacological Activities ◽

Therapeutic Drugs ◽

Potential Source ◽

Therapeutic Value ◽

Wide Range ◽

Novel Structures

With the advent of green pharmaceuticals, the secondary metabolites derived from plants have provided numerous leads for the development of a wide range of therapeutic drugs; however the discovery of new drugs with novel structures has declined in the past few years. Cryptogams including lichens, bryophytes, and pteridophytes represent a group of small terrestrial plants that remain relatively untouched in the drug discovery process though some have been used as ethnomedicines by various tribes worldwide. Studies of their secondary metabolites are recent but reveal unique secondary metabolites which are not synthesized by higher plants. These compounds can have the potential to develop more potential herbal drugs for prevention and treatment of diseases The present article . deals with the secondary metabolites and pharmacological activities of cryptogams with an objective to bring them forth as potential source of biodynamic compounds of therapeutic value.

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The Genus Lagochilus (Lamiaceae): A Review of Its Diversity, Ethnobotany, Phytochemistry, and Pharmacology

Plants ◽

10.3390/plants10010132 ◽

2021 ◽

Vol 10 (1) ◽

pp. 132

Author(s):

Nilufar Z. Mamadalieva ◽

Davlat Kh. Akramov ◽

Ludger A. Wessjohann ◽

Hidayat Hussain ◽

Chunlin Long ◽

...

Keyword(s):

Secondary Metabolites ◽

Chemical Constituents ◽

Iridoid Glycosides ◽

Herbal Medicines ◽

Future Research ◽

South Central ◽

Pharmacological Studies ◽

Central South

The genus Lagochilus (Lamiaceae) is native to Central, South-Central, and Eastern Asia. It comprises 44 species, which have been commonly used as herbal medicines for the treatments of various ailments for thousands of years, especially in Asian countries. This review aims to summarize the chemical constituents and pharmacological activities of species from the genus Lagochilus to unveil opportunities for future research. In addition, we provide some information about their traditional uses, botany, and diversity. More than 150 secondary metabolites have been reported from Lagochilus, including diterpenes, flavonoids, phenolic compounds, triterpenoids, iridoid glycosides, lignans, steroids, alkaloids, polysaccharides, volatile, non-volatile and aromatic compounds, lipids, carbohydrates, minerals, vitamins, and other secondary metabolites. In vitro and in vivo pharmacological studies on the crude extracts, fractions, and isolated compounds from Lagochilus species showed hemostatic, antibacterial, anti-inflammatory, anti-allergic, cytotoxic, enzyme inhibitory, antispasmodic, hypotensive, sedative, psychoactive, and other activities.

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Antifungal and cytotoxic activities of the secondary metabolites from endophytic fungus Massrison sp.

Phytomedicine ◽

10.1016/j.phymed.2011.01.019 ◽

2011 ◽

Vol 18 (10) ◽

pp. 859-862 ◽

Cited By ~ 28

Author(s):

Zhen-Liang Sun ◽

Ming Zhang ◽

Ji-Fa Zhang ◽

Jing Feng

Keyword(s):

Secondary Metabolites ◽

Endophytic Fungus ◽

Cytotoxic Activities

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Pharmacology and Phytochemistry of Ecuadorian Medicinal Plants: An Update and Perspectives

Pharmaceuticals ◽

10.3390/ph14111145 ◽

2021 ◽

Vol 14 (11) ◽

pp. 1145

Author(s):

Chabaco Armijos ◽

Jorge Ramírez ◽

Melissa Salinas ◽

Giovanni Vidari ◽

Alírica I. Suárez

Keyword(s):

Chemical Composition ◽

Medicinal Plants ◽

Secondary Metabolites ◽

Essential Oils ◽

Volatile Compounds ◽

Biological Activities ◽

Indigenous Communities ◽

Therapeutic Agents ◽

Practical Applications ◽

Pharmacological Studies

The use of plants as therapeutic agents is part of the traditional medicine that is practiced by many indigenous communities in Ecuador. The aim of this study was to update a review published in 2016 by including the studies that were carried out in the period 2016–July 2021 on about 120 Ecuadorian medicinal plants. Relevant data on raw extracts and isolated secondary metabolites were retrieved from different databases, resulting in 104 references. They included phytochemical and pharmacological studies on several non-volatile compounds, as well as the chemical composition of essential oils (EOs). The tested biological activities are also reported. The potential of Ecuadorian plants as sources of products for practical applications in different fields, as well the perspectives of future investigations, are discussed in the last part of the review.

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Actinomycetes as An Environmental Scrubber

10.5772/intechopen.99187 ◽

2021 ◽

Author(s):

Sutaria Devanshi ◽

Kamlesh R. Shah ◽

Sudipti Arora ◽

Sonika Saxena

Keyword(s):

Secondary Metabolites ◽

Agricultural Waste ◽

Chemical Compounds ◽

Filamentous Bacteria ◽

Primary And Secondary Metabolites ◽

Sustainable Environment ◽

Potential Source ◽

Wide Range ◽

Bioactive Secondary Metabolites ◽

Broad Variety

Biotechnological tools engaged in the bioremediation process are in reality, sophisticated and dynamic in character. For specialized reasons, a broad variety of such devices are employed to produce a safe and balanced environment free of all types of toxins and so make life simpler for humans on planet Earth. Actinomycetes is one of these extremely important and functionally helpful groups. They can be used for a variety of bioremediation objectives, including biotransformation, biodegradation, and many more. Actinomycetes are one of the most varied groups of filamentous bacteria, capable of prospering in a variety of ecological settings because to their bioactive capabilities. They’re famous for their metabolic diversity, which includes the synthesis of commercially useful primary and secondary metabolites. They produce a range of enzymes capable of totally destroying all of the constituents. They are well-known for their ability to produce bioactive secondary metabolites. Members of various genera of Actinomycetes show promise for application in the bioconversion of underutilized urban and agricultural waste into high-value chemical compounds. The most potential source is a wide range of important enzymes, some of which are synthesized on an industrial scale, but there are many more that have yet to be discovered. Bioremediation methods, which use naturally existing microbes to clear residues and contaminated regions of dangerous organic chemicals, are improving all the time. In the realm of biotechnological science, the potential of actinomycetes for bioremediation and the synthesis of secondary metabolites has opened up intriguing prospects for a sustainable environment.

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An atlas of skin diseases in the tropics

Transactions of the Royal Society of Tropical Medicine and Hygiene ◽

10.1016/s0035-9203(33)90046-2 ◽

1933 ◽

Vol 26 (4) ◽

pp. 406

Author(s):

J.M.H. Macleod

Keyword(s):

Skin Diseases ◽

The Tropics

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The use of diets containing high levels of copra meal for growing/finishing pigs

Proceedings of the British Society of Animal Production (1972) ◽

10.1017/s0308229600035327 ◽

1997 ◽

Vol 1987 ◽

pp. 97-97

Author(s):

P.J. Thorne ◽

J. Wiseman ◽

D.J.A. Cole

Keyword(s):

Coconut Oil ◽

Oil Industry ◽

The Philippines ◽

Finishing Pigs ◽

Poor Growth ◽

Copra Meal ◽

Potential Source ◽

Tropical Conditions ◽

The University ◽

The Tropics

Copra meal is a by-product of the coconut oil industry and is a potential source of protein and energy in the diets of pigs and poultry in the tropics. However, previous studies with pigs have suggested that its use may be limited because of poor growth performance associated with levels of inclusion above 300 g/kg (Creswell and Brooks, 1971). The experiment reported here and conducted under tropical conditions at the University of the Philippines at Los Banos was designed to study possible ways of feeding copra meal at levels of inclusion greater than 300 g/kg in the diets of pigs while maintaining acceptable animal performance.

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Secondary metabolites of Phlebopus species from Northern Thailand

Mycological Progress ◽

10.1007/s11557-020-01643-y ◽

2020 ◽

Vol 19 (12) ◽

pp. 1525-1536

Author(s):

Boontiya Chuankid ◽

Hedda Schrey ◽

Benjarong Thongbai ◽

Olivier Raspé ◽

Norbert Arnold ◽

...

Keyword(s):

Secondary Metabolites ◽

2D Nmr ◽

Cytotoxic Activities ◽

Tumor Cell Lines ◽

Submerged Cultures ◽

Esi Ms ◽

Spectroscopic Analyses ◽

New Compounds ◽

Comprehensive Characterization

AbstractSubmerged cultures of the edible mushrooms Phlebopus portentosus and Phlebopus spongiosus were screened for their secondary metabolites by HPLC-UV/Vis and HR-LC-ESI-MS. Two new compounds, 9′-hydroxyphenyl pulvinone (1), containing an unusual pulvinone structure, and phlebopyron (2), together with the seven known pigments, atromentic acid (3), xerocomic acid (4), variegatic acid (5), methyl atromentate (6), methyl isoxerocomate (7), methyl variegatate (8), and variegatorubin (9) were isolated from the cultures. Their structures were assigned on the basis of extensive 1D/2D NMR spectroscopic analyses, as well as HR-ESI-MS, and HR-ESI-MS/MS measurements. Furthermore, the isolated compounds were evaluated for their antimicrobial and cytotoxic properties. 9′-hydroxyphenyl pulvinone (1), xerocomic acid (4), and methyl variegatate (8) exhibited weak to moderate cytotoxic activities against several tumor cell lines. The present paper provides a comprehensive characterization of pigments from the class of pulvinic acids that are present in the basidiomes of many edible bolete species.

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