scholarly journals Overview of Recent Advances in the Design of Plasmonic Fiber-Optic Biosensors

Biosensors ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 77 ◽  
Author(s):  
Yashar Esfahani Monfared

Plasmonic fiber-optic biosensors combine the flexibility and compactness of optical fibers and high sensitivity of nanomaterials to their surrounding medium, to detect biological species such as cells, proteins, and DNA. Due to their small size, accuracy, low cost, and possibility of remote and distributed sensing, plasmonic fiber-optic biosensors are promising alternatives to traditional methods for biomolecule detection, and can result in significant advances in clinical diagnostics, drug discovery, food process control, disease, and environmental monitoring. In this review article, we overview the key plasmonic fiber-optic biosensing design concepts, including geometries based on conventional optical fibers like unclad, side-polished, tapered, and U-shaped fiber designs, and geometries based on specialty optical fibers, such as photonic crystal fibers and tilted fiber Bragg gratings. The review will be of benefit to both engineers in the field of optical fiber technology and scientists in the fields of biosensing.

1998 ◽  
Vol 20 (2) ◽  
pp. 103-112 ◽  
Author(s):  
H. Wen ◽  
D.G. Wiesler ◽  
A. Tveten ◽  
B. Danver ◽  
A. Dandridge

This paper presents several designs of high-sensitivity, compact fiber-optic ultrasound sensors that may be used for medical imaging applications. These sensors translate ultrasonic pulses into strains in single-mode optical fibers, which are measured with fiber-based laser interferometers at high precision. The sensors are simpler and less expensive to make than piezoelectric sensors, and are not susceptible to electromagnetic interference. It is possible to make focal sensors with these designs, and several schemes are discussed. Because of the minimum bending radius of optical fibers, the designs are suitable for single element sensors rather than for arrays.


1987 ◽  
Vol 41 (5) ◽  
pp. 779-785 ◽  
Author(s):  
Brad Tenge ◽  
B. R. Buchanan ◽  
D. E. Honigs

Chemical sensing in remote, hostile environments is possible with optical fiber technology. Telecommunications optical fiber transmits light in the near-infrared region. The least amount of attenuation of transmitted power is between 1050 nm and 1600 nm. It is a natural step to apply near-infrared analysis techniques to data remotely collected over optical fibers. A feasibility study is conducted to see how well calibration techniques, Multiple Linear Regression with either Step-up search or All Possible Combinations search, perform in the fiber optic region of the near-infrared. Calibration in the 1131–1531 nm region is compared to calibration in the 1131–2531 nm region. The latter region is considered more information-rich than the former. In spite of this, examination of the predictive power of calibration models formed strictly from fiberoptic-region absorbance data indicates that this region contains useful analytical informaton.


2018 ◽  
Vol 96 (4) ◽  
pp. 359-365
Author(s):  
Yanping Xu ◽  
Xiaoyi Bao

Micro-structured fibers are important devices that have drawn intensive attentions and proved to be powerful platforms for various applications over the past decades due to their remarkable merits and advantages, such as small footprint, immunity to electromagnetic interferences, light weight, high physical flexibility, and low cost. Modifications in optical fibers can be used as light-steering elements to excite and couple back different core and cladding modes and form various in-fiber structures, including in-line fiber interferometer, fiber micro-cantilever, fiber random gratings, and so on. These micro-structures, when applied as fiber-optic sensors in the presence of external disturbances, show high sensitivity in terms of the significant changes in the guided light features. Novel micro-structured bend-insensitive fiber-based in-line fiber interferometer and micro-cantilever have been proposed to realize both static and dynamic parameter measurements, including temperature, axial strain, surrounding refractive index, and vibration. We have also developed a novel fiber random grating along with a spectral correlation algorithm for simultaneous measurement of three static measurands. To move a step forward, random fiber lasers based on fiber random grating are achieved for either improving the laser performances or sensing applications of temperature, strain, and ultrasound measurements with high sensitivity.


2019 ◽  
Vol 11 (1) ◽  
pp. 13
Author(s):  
Joanna Ewa Moś ◽  
Karol Antoni Stasiewicz ◽  
Leszek Roman Jaroszewicz

The work describes the technology of a liquid crystal cell with a tapered optical fiber as an element providing light. The tapered optical fiber with the total optical loss of 0.22 ± 0.07 dB, the taper waist diameter of 15.5 ± 0.5 μm, and the elongation of 20.4 ± 0.3 mm has been used. The experimental results are presented for a liquid crystal cell filled with a mixture 1550* for parallel orientation of LC molecules to the cross section of the taper waist. Measurement results show the influence of the electrical field with voltage in the range of 0-200 V, without, as well as with different modulation for spectral characteristics. The sinusoidal and square signal shapes are used with a 1-10 Hz frequency range. Full Text: PDF ReferencesZ. Liu, H. Y. Tam, L. Htein, M. L.Vincent Tse, C. Lu, "Microstructured Optical Fiber Sensors", J. Lightwave Technol. 35, 16 (2017). CrossRef T. R. Wolinski, K. Szaniawska, S. Ertman1, P. Lesiak, A. W. Domański, R. Dabrowski, E. Nowinowski-Kruszelnicki, J. Wojcik "Influence of temperature and electrical fields on propagation properties of photonic liquid-crystal fibres", Meas. Sci. Technol. 17, 5 (2006). CrossRef K. Nielsen, D. Noordegraaf, T. Sørensen, A. Bjarklev,T. Hansen, "Selective filling of photonic crystal fibres", J. Opt. A: Pure Appl. Opt. 7, 8 (2005). CrossRef A. A. Rifat, G. A. Mahdiraji, D. M. Chow, Y, Gang Shee, R. Ahmed, F. Rafiq, M Adikan, "Photonic Crystal Fiber-Based Surface Plasmon Resonance Sensor with Selective Analyte Channels and Graphene-Silver Deposited Core", Sensors 15, 5 (2015) CrossRef Y. Huang, Z.Tian, L.P. Sun, D. Sun, J.Li, Y.Ran, B.-O. Guan "High-sensitivity DNA biosensor based on optical fiber taper interferometer coated with conjugated polymer tentacle", Opt. Express 23, 21 (2015). CrossRef X. Wang, O. S. Wolfbeis, "The 2016 Annual Review Issue", Anal. Chem., 88, 1 (2016). CrossRef Ye Tian, W. Wang, N. Wu, X. Zou, X.Wang, "Tapered Optical Fiber Sensor for Label-Free Detection of Biomolecules", Sensors 11, 4 (2011). CrossRef O. Katsunari, Fundamentals of Optical Waveguides, (London, Academic Press, (2006). DirectLink A. K. Sharma, J. Rajan, B.D. Gupta, "Fiber-Optic Sensors Based on Surface Plasmon Resonance: A Comprehensive Review", IEEE Sensors Journal 7, 8 (2007). CrossRef C. Caucheteur, T. Guo, J. Albert, "Review of plasmonic fiber optic biochemical sensors: improving the limit of detection", Anal. Bioanal.Chem. 407, 14 (2015). CrossRef S. F. Silva L. Coelho, O. Frazão, J. L. Santos, F. X.r Malcata, "A Review of Palladium-Based Fiber-Optic Sensors for Molecular Hydrogen Detection", IEEE SENSORS JOURNAL 12, 1 (2012). CrossRef H. Waechter, J. Litman, A. H. Cheung, J. A. Barnes, H.P. Loock, "Chemical Sensing Using Fiber Cavity Ring-Down Spectroscopy", Sensors 10, 3 (2010). CrossRef S. Zhu, F. Pang, S. Huang, F.Zou, Y.Dong, T.Wang, "High sensitivity refractive index sensor based on adiabatic tapered optical fiber deposited with nanofilm by ALD", Opt. Express 23, 11 (2015). CrossRef L. Zhang, J. Lou, L. Tong, "Micro/nanofiber optical sensors", Photonics sensor 1, 1 (2011). CrossRef L.Tong, J. Lou, E. Mazur, "Single-mode guiding properties of subwavelength-diameter silica and silicon wire waveguides", Opt. Express 11, 6 (2004). CrossRef H. Moyyed, I. T. Leite, L. Coelho, J. L. Santos, D. Viegas, "Analysis of phase interrogated SPR fiber optic sensors with bimetallic layers", IEEE Sensors Journal 14, 10 (2014). CrossRef A. González-Cano, M. Cruz Navarette, Ó. Esteban, N. Diaz Herrera , "Plasmonic sensors based on doubly-deposited tapered optical fibers", Sensors 14, 3 (2014). CrossRef K. A. Stasiewicz, J.E. Moś, "Threshold temperature optical fibre sensors", Opt. Fiber Technol. 32, (2016). CrossRef L. Zhang, F. Gu, J. Lou, X. Yin, L. Tong, "Fast detection of humidity with a subwavelength-diameter fiber taper coated with gelatin film", Opt. Express 16, 17 (2008). CrossRef S.Zhu, F.Pang, S. Huang, F. Zou, Q. Guo, J. Wen, T. Wang, "High Sensitivity Refractometer Based on TiO2-Coated Adiabatic Tapered Optical Fiber via ALD Technology", Sensors 16, 8 (2016). CrossRef G.Brambilla, "Optical fibre nanowires and microwires: a review", J. Optics 12, 4 (2010) CrossRef M. Ahmad, L.L. Hench, "Effect of taper geometries and launch angle on evanescent wave penetration depth in optical fibers", Biosens. Bioelectron. 20, 7 (2005). CrossRef L.M. Blinov, Electrooptic Effects in Liquid Crystal Materials (New York, Springftianer, 1994). CrossRef L. Scolari, T.T. Alkeskjold, A. Bjarklev, "Tunable Gaussian filter based on tapered liquid crystal photonic bandgap fibre", Electron. Lett. 42, 22 (2006). CrossRef J. Moś, M. Florek, K. Garbat, K.A. Stasiewicz, N. Bennis, L.R. Jaroszewicz, "In-Line Tunable Nematic Liquid Crystal Fiber Optic Device", J. of Lightwave Technol. 36, 4 (2017). CrossRef J. Moś, K A Stasiewicz, K Garbat, P Morawiak, W Piecek, L R Jaroszewicz, "Tapered fiber liquid crystal hybrid broad band device", Phys. Scripta. 93, 12 (2018). CrossRef Ch. Veilleux, J. Lapierre, J. Bures, "Liquid-crystal-clad tapered fibers", Opt. Lett. 11, 11 (1986). CrossRef R. Dąbrowski, K. Garbat, S. Urban, T.R. Woliński, J. Dziaduszek, T. Ogrodnik, A,Siarkowska, "Low-birefringence liquid crystal mixtures for photonic liquid crystal fibres application", Liq. Cryst. 44, (2017). CrossRef S. Lacroix, R. J. Black, Ch. Veilleux, J. Lapierre, "Tapered single-mode fibers: external refractive-index dependence", Appl. Opt., 25, 15 (1986). CrossRef J.F. Henninot, D. Louvergneaux , N.Tabiryan, M. Warenghem, "Controlled Leakage of a Tapered Optical Fiber with Liquid Crystal Cladding", Mol. Cryst.and Liq.Cryst., 282, 1(1996). CrossRef


2019 ◽  
Vol 9 (5) ◽  
pp. 949 ◽  
Author(s):  
M. Gandhi ◽  
Suoda Chu ◽  
K. Senthilnathan ◽  
P. Babu ◽  
K. Nakkeeran ◽  
...  

The survey focuses on the most significant contributions in the field of fiber optic plasmonic sensors (FOPS) in recent years. FOPSs are plasmonic sensor-based fiber optic probes that use an optical field to measure the biological agents. Owing to their high sensitivity, high resolution, and low cost, FOPS turn out to be potential alternatives to conventional biological fiber optic sensors. FOPS use optical transduction mechanisms to enhance sensitivity and resolution. The optical transduction mechanisms of FOPS with different geometrical structures and the photonic properties of the geometries are discussed in detail. The studies of optical properties with a combination of suitable materials for testing the biosamples allow for diagnosing diseases in the medical field.


2008 ◽  
Vol 2008 ◽  
pp. 1-29 ◽  
Author(s):  
M. Consales ◽  
A. Cutolo ◽  
M. Penza ◽  
P. Aversa ◽  
M. Giordano ◽  
...  

In this contribution, a review of the development of high-performance optochemical nanosensors based on the integration of carbon nanotubes with the optical fiber technology is presented. The paper first provide an overview of the amazing features of carbon nanotubes and their exploitation as highly adsorbent nanoscale materials for gas sensing applications. Successively, the attention is focused on the operating principle, fabrication, and characterization of fiber optic chemosensors in the Fabry-Perot type reflectometric configuration, realized by means of the deposition of a thin layer of single-walled carbon nanotubes (SWCNTs) upon the distal end of standard silica optical fibers. This is followed by an extensive review of the excellent sensing capabilities of the realized SWCNTs-based chemical nanosensors against volatile organic compounds and other pollutants in different environments (air and water) and operating conditions (room temperature and cryogenic temperatures). The experimental results reported here reveal that ppm and sub-ppm chemical detection limits, low response times, as well as fast and complete recovery of the sensor responses have been obtained in most of the investigated cases. This evidences the great potentialities of the proposed photonic nanosensors based on SWCNTs to be successfully employed for practical environmental monitoring applications both in liquid and vapor phase as well as for space. Furthermore, the use of novel SWCNTs-based composites as sensitive fiber coatings is proposed to enhance the sensing performance and to improve the adhesion of carbon nanotubes to the fiber surface. Finally, new advanced sensing configurations based on the use of hollow-core optical fibers coated and partially filled by carbon nanotubes are also presented.


Sensors ◽  
2020 ◽  
Vol 20 (8) ◽  
pp. 2233 ◽  
Author(s):  
Ning Zhou ◽  
Pinggang Jia ◽  
Jia Liu ◽  
Qianyu Ren ◽  
Guowen An ◽  
...  

A reflective intensity-modulated fiber-optic sensor based on microelectromechanical systems (MEMS) for pressure measurements is proposed and experimentally demonstrated. The sensor consists of two multimode optical fibers with a spherical end, a quartz tube with dual holes, a silicon sensitive diaphragm, and a high borosilicate glass substrate (HBGS). The integrated sensor has a high sensitivity due to the MEMS technique and the spherical end of the fiber. The results show that the sensor achieves a pressure sensitivity of approximately 0.139 mV/kPa. The temperature coefficient of the proposed sensor is about 0.87 mV/°C over the range of 20 °C to 150 °C. Furthermore, due to the intensity mechanism, the sensor has a relatively simple demodulation system and can respond to high-frequency pressure in real time. The dynamic response of the sensor was verified in a 1 kHz sinusoidal pressure environment at room temperature.


2020 ◽  
Vol 12 (1) ◽  
pp. 4
Author(s):  
Yuqing Li ◽  
Kuo Li ◽  
Guoyong Liu ◽  
Juan Tian ◽  
Yanchun Wang

Fiber Bragg grating (FBG) accelerometers using transverse forces have higher sensitivity but lower resonant frequency than ones using axial forces. By shortening the distance between the two fixed ends of the FBG, the resonant frequency can be improved without lowing the sensitivity. Here, a compact FBG accelerometer using transverse forces with a slightly pre-relaxed FBG and 25mm distance between the two fixed ends has been demonstrated with the crest-to-trough sensitivity 1.1nm/g at 5Hz and the resonant frequency 42Hz. It reveals that making the FBG slightly pre-relaxed rather than pre-stretched also improves the tradeoff between the sensitivity and resonant frequency. Full Text: PDF References:Kawasaki, B. S. , Hill, K. O , Johnson, D. C. , & Fujii, Y. , "Narrow-band Bragg reflectors in optical fibers", Optics Letters 3, 66 (1978) [CrossRef]K. O. Hill, and G. Meltz, "Fiber Bragg grating technology fundamentals and overview", Journal of Lightwave Technology 15, 1263 (1997) [CrossRef]B. Lee, "Review of the present status of optical fiber sensors", Optical Fiber Technology, 9, 57-79 (2003) [CrossRef]Laudati, A. , Mennella, F. , Giordano, M. , D"Altrui, G. , Tassini, C. C. , & Cusano, A., "A Fiber-Optic Bragg Grating Seismic Sensor", IEEE Photonics Technology Letters, 19, 1991 (2007) [CrossRef]P. F. Costa Antunes, C. A. Marques, H. Varum, and P. S. Andre, "Biaxial Optical Accelerometer and High-Angle Inclinometer With Temperature and Cross-Axis Insensitivity", IEEE Sens. J. 12, 2399 (2012) [CrossRef]Guo, Y. , Zhang, D. , Zhou, Z. , Xiong, L. , & Deng, X., "Welding-packaged accelerometer based on metal-coated FBG", Chinese Optics Letters, 11, 21 (2013). [CrossRef]Zhang, Y. , Zhang, W. , Zhang, Y. , Chen, L. , Yan, T. , & Wang, S. , et al., "2-D Medium–High Frequency Fiber Bragg Gratings Accelerometer", IEEE Sensors Journal, 17, 614(2017) [CrossRef]Xiu-bin Zhu, "A novel FBG velocimeter with wind speed and temperature synchronous measurement", Optoelectronics Letters, 14, 276-279 (2018) [CrossRef]Li, K. , Yau, M. H. , Chan, T. H. T. , Thambiratnam, D., "Fiber Bragg grating strain modulation based on nonlinear string transverse-force amplifier", & Tam, H. Y. , Optics Letters, 38, 311 (2013) [CrossRef]Li, K. , Chan, T. H. T. , Yau, M. H. , Nguyen, T. , Thambiratnam, D. P. , & Tam, H. Y., "Very sensitive fiber Bragg grating accelerometer using transverse forces with an easy over-range protection and low cross axial sensitivity", Applied Optics, 52, 6401 (2013) [CrossRef]Li, K. , Chan, T. H. T. , Yau, M. H. , Thambiratnam, D. P. , & Tam, H. Y., "Biaxial Fiber Bragg Grating Accelerometer Using Axial and Transverse Forces", IEEE Photonics Technology Letters, 26, 1549 (2014). [CrossRef]Li, K. , Chan, T. H. , Yau, M. H. , Thambiratnam, D. P. , & Tam, H. Y., "Experimental verification of the modified spring-mass theory of fiber Bragg grating accelerometers using transverse forces", Applied Optics, 53, 1200-1211(2014) [CrossRef]


Author(s):  
Jovan S. Bajić ◽  
Dragan Z. Stupar ◽  
Lazo M. Manojlović ◽  
Miloš P. Slankamenac ◽  
Miloš B. Živanov

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