scholarly journals Statistical Permutation Test Reveals Progressive and Region-Specific Iron Accumulation in the Thalami of Children with Aspartylglucosaminuria

2020 ◽  
Vol 10 (10) ◽  
pp. 677
Author(s):  
Viljami Sairanen ◽  
Anna Tokola ◽  
Ritva Tikkanen ◽  
Minna Laine ◽  
Taina Autti
Keyword(s):  
Multivariate Regression ◽  
Permutation Test ◽  
Test Group ◽  
Iron Accumulation ◽  
Group Differences ◽  
P Value ◽  
Lysosomal Storage ◽  
Cohen’S D ◽  
Cohen's D ◽  
Eventual Death

Aspartylglucosaminuria (AGU) is a rare lysosomal storage disorder causing developmental delay, intellectual disability, and eventual death. A distinct feature in AGU is iron accumulation within the thalamus. Our aim is to demonstrate that susceptibility-weighted images (SWI) could be used as an MRI biomarker to evaluate the response within the AGU population to newly evolving treatments. SWI from 16 patients with AGU and 16 age-matched controls were used in the analysis. Thalamic volume with an iron accumulation was identified using a permutation test. Group differences were investigated for both the complete thalamus and the iron accumulation regions. Group-wise age correlation within these volumes were assessed with analysis of variance and multivariate regression. We found a statistically significant and large difference (p-value = 0.01, Cohen’s D = 0.97) for the whole thalamus comparison and an even greater difference in the iron accumulation regions (p-value < 0.01, Cohen’s D = 3.52). Furthermore, we found strong evidence for iron accumulation as a linear function of age with R2 = 0.65 only for AGU. The statistical analysis of SWI provides tools for assessing the degree of iron accumulation. This method could be used to study the response to treatments, in that a successful treatment would be expected to result in a decline in iron accumulation.

Estimating Subgroup Differences in Staffing Research When the Selection Mechanism Is Unknown: A Response to Li’s Case IV Correction

2018 ◽  
Vol 23 (2) ◽  
pp. 367-384 ◽  
Author(s):  
Dustin A. Fife ◽  
Jorge Mendoza ◽  
Eric Day ◽  
Robert Terry
Keyword(s):  
Monte Carlo Simulation ◽  
Monte Carlo ◽  
Group Membership ◽  
Group Differences ◽  
Selection Mechanism ◽  
Range Restriction ◽  
Subgroup Differences ◽  
Cohen’S D ◽  
Selection Decisions ◽  
Cohen's D

When estimating subgroup differences on incumbents, range restriction may bias estimates. Bobko, Roth, and Bobko recognized this problem and developed a Case II and Case III correction for Cohen’s d. Subsequently, Li developed a Case IV correction, which seeks to estimate group differences on a predictor using only incumbent data but must assume that group membership (e.g., ethnicity) plays no role in selection decisions. In this paper, we extend Li’s correction and relax this assumption. In addition, this new correction allows for the estimation of subgroup differences on both the criterion and predictor. Using Monte Carlo simulation, we study the performance of both estimators under situations where Li’s assumptions are violated and demonstrate that this new procedure almost always outperforms Li’s Case IV correction and does so with greater precision. We also provide R code to assist applied researchers in using these corrections.

Improving the Accuracy of Firearm Identification in a Dynamic Use of Force Scenario

2020 ◽  
pp. 109861112094438
Author(s):  
M. Hunter Martaindale
Keyword(s):  
Use Of Force ◽  
Test Group ◽  
Law Enforcement Officers ◽  
Control Group ◽  
Force Scenario ◽  
Cohen’S D ◽  
Cohen's D ◽  
Speed And Accuracy ◽  
Decision Errors ◽  
Second Use

Law enforcement officers are sometimes required to make split-second use of force decisions. One factor that can impact their decision-making process is the presence of a weapon. This experiment sought to improve the speed and accuracy of weapon identification in a dynamic use of force scenario through the principles of deliberate practice. This research utilized randomized control trial with random assignment to either a control or test condition. Eighty-seven participants completed the pretest, intervention, and posttest. Participants’ vision was recorded via a mobile vision-tracker. With only 20 minutes of training, the test group made 1/3 the amount of decision errors as the control group (Cohen’s d = 0.95). The test group was about 16% faster than the control group at visually finding the object in the suspect’s hand and determining if it was a gun or not (Cohen’s d = 0.91).

scholarly journals Effect Size Guidelines, Sample Size Calculations, and Statistical Power in Gerontology

2019 ◽  
Vol 3 (4) ◽  
Author(s):  
Christopher R Brydges
Keyword(s):  
Individual Differences ◽  
Sample Size ◽  
Effect Size ◽  
Effect Sizes ◽  
Group Differences ◽  
Cohen’S D ◽  
Pearson's R ◽  
Sample Size Calculations ◽  
Cohen's D ◽  
Pearson’S R

Abstract Background and Objectives Researchers typically use Cohen’s guidelines of Pearson’s r = .10, .30, and .50, and Cohen’s d = 0.20, 0.50, and 0.80 to interpret observed effect sizes as small, medium, or large, respectively. However, these guidelines were not based on quantitative estimates and are only recommended if field-specific estimates are unknown. This study investigated the distribution of effect sizes in both individual differences research and group differences research in gerontology to provide estimates of effect sizes in the field. Research Design and Methods Effect sizes (Pearson’s r, Cohen’s d, and Hedges’ g) were extracted from meta-analyses published in 10 top-ranked gerontology journals. The 25th, 50th, and 75th percentile ranks were calculated for Pearson’s r (individual differences) and Cohen’s d or Hedges’ g (group differences) values as indicators of small, medium, and large effects. A priori power analyses were conducted for sample size calculations given the observed effect size estimates. Results Effect sizes of Pearson’s r = .12, .20, and .32 for individual differences research and Hedges’ g = 0.16, 0.38, and 0.76 for group differences research were interpreted as small, medium, and large effects in gerontology. Discussion and Implications Cohen’s guidelines appear to overestimate effect sizes in gerontology. Researchers are encouraged to use Pearson’s r = .10, .20, and .30, and Cohen’s d or Hedges’ g = 0.15, 0.40, and 0.75 to interpret small, medium, and large effects in gerontology, and recruit larger samples.

scholarly journals Effect Size Interpretation, Sample Size Calculation, and Statistical Power in Gerontology

2019 ◽  
Author(s):  
Christopher Brydges
Keyword(s):  
Individual Differences ◽  
Sample Size ◽  
Effect Size ◽  
Sample Size Calculation ◽  
Effect Sizes ◽  
Group Differences ◽  
Cohen’S D ◽  
Pearson's R ◽  
Cohen's D ◽  
Pearson’S R

Background and Objectives: Researchers typically use Cohen’s guidelines of Pearson’s r = .10, .30, and .50, and Cohen’s d = 0.20, 0.50, and 0.80 to interpret observed effect sizes as small, medium, or large, respectively. However, these guidelines were not based on quantitative estimates, and are only recommended if field-specific estimates are unknown. The current study investigated the distribution of effect sizes in both individual differences research and group differences research in gerontology to provide estimates of effect sizes in the field.Research Design and Methods: Effect sizes (Pearson’s r, Cohen’s d, and Hedges’ g) were extracted from meta-analyses published in ten top-ranked gerontology journals. The 25th, 50th, and 75th percentile ranks were calculated for Pearson’s r (individual differences) and Cohen’s d or Hedges’ g (group differences) values as indicators of small, medium, and large effects. A priori power analyses were conducted for sample size calculations given the observed effect size estimates.Results: Effect sizes of Pearson’s r = .12, .20, and .32 for individual differences research and Hedges’ g = 0.16, 0.38, and 0.76 for group differences research were interpreted as small, medium, and large effects in gerontology. Discussion and Implications: Cohen’s guidelines appear to overestimate effect sizes in gerontology. Researchers are encouraged to use Pearson’s r = .10, .20, and .30, and Cohen’s d or Hedges’ g = 0.15, 0.40, and 0.75 to interpret small, medium, and large effects in gerontology, and recruit larger samples.

scholarly journals The Effect of Classifying Vocabulary into EFL Student’s Reading Comprehension

2021 ◽  
pp. 62
Author(s):  
Rosa Marianella Contreras-Jordán ◽  
María Rossana Ramírez-Ávila
Keyword(s):  
Reading Comprehension ◽  
Public University ◽  
Future Research ◽  
P Value ◽  
Parts Of Speech ◽  
Cohen’S D ◽  
Proficiency Level ◽  
Small Effect Size ◽  
Efl Teachers ◽  
Cohen's D

This study examined the effect of classifying vocabulary into parts of speech using Google Drive sheets in order to improve reading comprehension. Participants were 20 EFL stu- dents at a public university in Ecuador whose proficiency level in English was A1 and who were having problems understanding short passages in English. For this action research study, we used quantitative data gathered from pre- and post-surveys, quizzes, and pre- and post-tests. Results from the pre- and post-tests showed that the students improved their word recognition skills by 17% , which enhanced their reading comprehension by 14%. This was corroborated by the p-value =0.000, which shows that the results were due to classifying parts of speech. Additionally, Cohen’s d = 1.02 in the vocabulary section indicates a large impact on learning. However, there was a small effect size (Cohen’s d= 0.39) in reading comprehension. Six quizzes were administered and three of them were compared. These demonstrated a steady improvement in students’ meaning recall and word usage. The results of the survey indicate that the students changed their perspective of learn- ing vocabulary positively after the intervention. The implications of this study can be extended to other EFL teachers in higher education institutions who would like to improve their students’ read- ing comprehension. Future research should evaluate other parts of speech. We also recommend replicating this study with students who have a higher proficiency level in English.

scholarly journals Beyond Reporting Statistical Significance: Identifying Informative Effect Sizes to Improve Scientific Communication

2018 ◽  
Author(s):  
Paul H. P. Hanel ◽  
David Marc Anton Mehler
Keyword(s):  
General Public ◽  
Scientific Community ◽  
Bayes Factor ◽  
Statistical Significance ◽  
Scientific Communication ◽  
Effect Sizes ◽  
P Value ◽  
Cohen’S D ◽  
Cohen's D

Transparent communication of research is key to foster understanding within and beyond the scientific community. Increased focus on reporting effect sizes in addition of p-value based significance statements may improve scientific communication with the general public. Across two studies (N = 446), we compared informativeness ratings for five effect sizes, Bayes Factor and commonly used significance statements. Results showed that Cohen’s U3 was rated as most informative. For example, 77% of participants found it more informative than Cohen’s d. We therefore suggest that Cohen’s U3 is used when scientific findings are communicated.

Phonologische Verarbeitung bei Grundschulkindern mit schwacher Lesefähigkeit

2013 ◽  
Vol 2 (4) ◽  
pp. 199-215 ◽  
Author(s):  
Maria Klatte ◽  
Claudia Steinbrink ◽  
Kirstin Bergström ◽  
Thomas Lachmann
Keyword(s):  
Cohen’S D ◽  
Phonologische Verarbeitung ◽  
Cohen's D

Defizite in der phonologischen Informationsverarbeitung werden heute als Kernsymptom der Lese-Rechtschreibstörung betrachtet. In Trainingsstudien mit betroffenen Kindern erwiesen sich Phonemwahrnehmungsfähigkeiten als trainierbar, und Programme, in denen Aufgaben zur phonologischen Bewusstheit mit der systematischen Vermittlung von Phonem-Graphem-Zuordnungen kombiniert wurden, zeigten Transfereffekte auf Lese- und Rechtschreibleistungen. Ausgehend von diesen Erkenntnissen wurde ein computerbasiertes Trainingsprogramm zur Förderung der Phonemwahrnehmung, der phonologischen Bewusstheit und der Graphem-Phonem-Zuordnungen für deutschsprachige Grundschulkinder mit Lese-Rechtschreibstörung entwickelt. Aufgrund der besonderen Relevanz der Vokallänge für die deutsche Orthographie enthält das Programm neben Aufgaben, die auf Konsonanten fokussieren, auch Vokallängenaufgaben. Bei der Konzipierung des Programms wurden etablierte, ursprünglich für andere Sprachen entwickelte Aufgaben an die deutsche Phonologie angepasst und in ein computerbasiertes Format übersetzt. Im Rahmen der vorliegenden Studie sollte überprüft werden, ob die konstruierten Trainingsaufgaben die spezifischen Defizite von Kindern mit Lese-Rechtschreibstörung wie intendiert abbilden. Hierzu wurden leseschwache Dritt- und Viertklässler (n = 35) mit mindestens durchschnittlichen Lesern derselben Klassenstufen (n = 75; Kontrollgruppe) hinsichtlich ihrer Leistungen in den Aufgaben verglichen. Die leseschwachen Kinder zeigten in allen Aufgaben schlechtere Leistungen als die Kontrollgruppe. Die Effektstärken der Gruppenunterschiede (Cohen's d) lagen im mittleren bis hohen Bereich (0.50 – 2.19). Die Ergebnisse bestätigen, dass die Aufgaben des Trainingsprogramms die spezifischen Defizite leseschwacher Kinder abbilden. Ein Training mit diesen Aufgaben erscheint daher grundsätzlich sinnvoll. Die Wirkungen eines solchen Trainings auf die schriftsprachlichen Leistungen von Kindern mit Lese-Rechtschreibstörung werden in zukünftigen Studien überprüft.

PENINGKATAN KUALITAS HIDUP MELALUI LOGOTERAPI PADA KLIEN YANG MENJALANI HEMODIALISIS

2019 ◽  
Vol 11 (1) ◽  
pp. 9-18
Author(s):  
Abdul Wakhid ◽  
Ana Puji Astuti ◽  
Maya Kurnia Dewi
Keyword(s):  
Quality Of Life ◽  
Renal Failure ◽  
Test Group ◽  
Sampling Technique ◽  
T Test ◽  
P Value ◽  
Number Of Patients ◽  
Post Test ◽  
The Mean

Logoterapi merupakan terapi untuk menemukan makna positif dibalik sebuah kejadian yang tidak diharapkan. Logoterapi dilaksanakan secara individu maupun berkelompok dalam bentuk konseling dan berorientasi pada pencarian makna hidup individu. Tujuan logoterapi meningkatkan makna pengalaman hidup individu yang diarahkan kepada pengambilan keputusan yang bertanggung jawab. Penelitian ini dilakukan dengan menggunakan rancangan pre-experiment dengan metode pre and post test group, artinya pengumpulan data dilakukan terhadap responden untuk membandingkan kualitas hidup sebelum dan sesudah dilakukan intervensi. Teknik pengambilan sampel dilakukan dengan metode total sampling yaitu pengambilan seluruh sampel dengan tetap memperhatikan kriteria yang telah ditetapkan. Jumlah pasien yang menjalani hemodialisis di RSUD Ungaran sebanyak 21 orang dan di RSUD Ambarawa sebanyak 25 pasien. Analisis data dilakukan dengan menggunakan uji t test dependent. Hasil penelitian didapatkan bahwa dari 46 responden didapatkan rata-rata skor kualitas hidup pasien yang mejalani hemodialisis sebesar 60.22 dengan skor terrendah 55 dan skor tertinggi 69. Bahwa dari 46 responden didapatkan rata-rata skor kualitas hidup pasien yang mejalani hemodialisis sebesar 88.72 dengan skor terrendah 79 dan skor tertinggi 103. Hasil uji statistik dengan uji t test dependent diketahui ada pengaruh logoterapi terhadap kemampuan memaknai hidup pada klien yang menjalani hemodialisis di RSUD Kabupaten Semarang (p value: 0,0001). Saran perlunya peningkatan kemampuan perawat dalam memberikan layanan kesehatan termasuk pemberian atau pemanduan penemuan makna hidup bagi pasien hemodialysis, agar selain dengan hemodialysis, ada faktor internal dari pasien yang dapat dijadikan sebagai motivasi untuk sembuh dari penyakit.   Kata Kunci: Logoterapi, kualitas hidup   IMPROVE THE QUALITY OF LIFE OF PATIENTS WITH RENAL FAILURE WHO UNDERWENT HEMODIALYSIS   ABSTRACT Logotherapy is a therapy to discover the positive meaning behind an unexpected event. Logotherapy is carried out individually or in groups in the form of counseling and oriented to the search for the meaning of individual life. This study aims to improve the quality of life of patients with renal failure who underwent hemodialysis. This research was conducted by using pre-experiment with pre-post test study. The sampling technique was done by the convenience sampling. The number of patients undergoing hemodialysis as many as 46 respondents. Data analysis was done by using test t test dependent. The result showed that from 46 respondents got the mean of quality of life of patients who had hemodialysis 60.22 with lowest score 55 and highest score 69. Whereas from 46 respondents got the mean score of life quality of patients who had hemodialysis 88.72 with score the lowest score 79 and the highest score 103. The result of statistical test with t test dependent is known there is influence of logoterapi to the ability of meaningful life on client who undergo hemodialysis at Semarang Regency hospitals (p value: 0.0001). Advice on the need to improve the nurse's ability to provide health services, including the provision or guidance of the discovery of the meaning of life for hemodialysis patients, in addition to hemodialysis, there are internal factors of the patient that can be used as a motivation to recover from illness.   Keywords: Logotherapy, quality of life, kidney failure.  

Political Inclusion Reduces Political Prejudice

2019 ◽  
Author(s):  
Jan G. Voelkel ◽  
Dongning Ren ◽  
Mark John Brandt
Keyword(s):  
The Political ◽  
Political Discussion ◽  
Total N ◽  
Cohen’S D ◽  
Promising Strategy ◽  
Political Inclusion ◽  
Cohen's D ◽  
Political Divide ◽  
Scenario Study ◽  
Fair Chance

The political divide is characterized by liberals and conservatives who hold strong prejudice against each other. Here we introduce one possible strategy for reducing political prejudice: political inclusion. We define political inclusion as receiving a fair chance to voice one’s opinions in a discussion of political topics with political outgroup members. This strategy may reduce political prejudice by inducing perceptions of the political outgroup as fair and respectful; however, such a strategy may also highlight conflicting attitudes and worldviews, thereby further exacerbating prejudice. In three preregistered studies (total N = 799), we test if political inclusion reduces or increases prejudice toward the political outgroup. Specifically, political inclusion was manipulated with either an imagined scenario (Study 1) or a concurrent experience in an ostensible online political discussion (Studies 2 &amp; 3). Across all studies, participants who were politically included by political outgroup members reported reduced prejudice toward their outgroup compared to participants in a neutral control condition (Cohen’s d [-0.27, -0.50]). This effect was mediated by perceptions of the political outgroup as fairer and less dissimilar in their worldviews. Our results indicate that political discussions that are politically inclusive do not cause additional prejudice via worldview conflict, but instead give others a feeling of being heard. It is a promising strategy to reduce political prejudice.

scholarly journals Lower Extremity Rehabilitation in Patients with Post-Stroke Sequelae through Virtual Reality Associated with Mirror Therapy

2021 ◽  
Vol 18 (5) ◽  
pp. 2654
Author(s):  
Roxana Steliana Miclaus ◽  
Nadinne Roman ◽  
Ramona Henter ◽  
Silviu Caloian
Keyword(s):  
Virtual Reality ◽  
Muscle Strength ◽  
Lower Extremity ◽  
Range Of Motion ◽  
Control Group ◽  
Mirror Therapy ◽  
Cohen’S D ◽  
Cohen's D ◽  
Experimental Group ◽  
Post Therapy

More innovative technologies are used worldwide in patient’s rehabilitation after stroke, as it represents a significant cause of disability. The majority of the studies use a single type of therapy in therapeutic protocols. We aimed to identify if the association of virtual reality (VR) therapy and mirror therapy (MT) exercises have better outcomes in lower extremity rehabilitation in post-stroke patients compared to standard physiotherapy. Fifty-nine inpatients from 76 initially identified were included in the research. One experimental group (n = 31) received VR therapy and MT, while the control group (n = 28) received standard physiotherapy. Each group performed seventy minutes of therapy per day for ten days. Statistical analysis was performed with nonparametric tests. Wilcoxon Signed-Rank test showed that both groups registered significant differences between pre-and post-therapy clinical status for the range of motion and muscle strength (p < 0.001 and Cohen’s d between 0.324 and 0.645). Motor Fugl Meyer Lower Extremity Assessment also suggested significant differences pre-and post-therapy for both groups (p < 0.05 and Cohen’s d 0.254 for the control group and 0.685 for the experimental group). Mann-Whitney results suggested that VR and MT as a therapeutic intervention have better outcomes than standard physiotherapy in range of motion (p < 0.05, Cohen’s d 0.693), muscle strength (p < 0.05, Cohen’s d 0.924), lower extremity functionality (p < 0.05, Cohen’s d 0.984) and postural balance (p < 0.05, Cohen’s d 0.936). Our research suggests that VR therapy associated with MT may successfully substitute classic physiotherapy in lower extremity rehabilitation after stroke.

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