scholarly journals Paradigm Shift in Radiation Biology/Radiation Oncology—Exploitation of the “H2O2 Effect” for Radiotherapy Using Low-LET (Linear Energy Transfer) Radiation such as X-rays and High-Energy Electrons

Cancers ◽  
2016 ◽  
Vol 8 (3) ◽  
pp. 28 ◽  
Author(s):  
Yasuhiro Ogawa
2012 ◽  
Vol 177 (5) ◽  
pp. 651-662 ◽  
Author(s):  
Lara Barazzuol ◽  
Raj Jena ◽  
Neil G. Burnet ◽  
Jonathan C. G. Jeynes ◽  
Michael J. Merchant ◽  
...  

2007 ◽  
Vol 254 (1) ◽  
pp. 54-62 ◽  
Author(s):  
Sami Benzina ◽  
Frederic Debomy ◽  
Jean-Pierre Bergerat ◽  
Jean-Marc Denis ◽  
John Gueulette ◽  
...  

2016 ◽  
Vol 1 (3) ◽  
pp. 145
Author(s):  
Nevy T. Putri ◽  
Sarianoferni Sarianoferni ◽  
Endah Wahjuningsih

Intraoral periapical radiograph examination is the additional examination which is the most widely used in Dentistry. This radiograph examination using an x-ray ionizing radiation with low LET (Linear Energy Transfer), and may affect submandibular salivary gland. Ionizing radiation exposure can cause damage by inducing a series of changes at the molecular and cellular level. This study aimed to prove the effects of x-ray ionizing radiation with low LET towards the catalase activity of Rattus norvegicus strain Wistar’s submandibular gland. The subjects were 28 male Wistar rats and divided into 4 groups (n=7). Three groups were exposed 4, 8 and 14 times to radiation with 0.002 µSv for each exposure. The catalase activity of each rat was examined by a spectrophotometer. Data were analyzed using one-way ANOVA followed by Bonferroni test. The results showed the average of catalase activity on Wistar rat’s submandibular gland, respectively for: 0.150±0.0895 (KK), 0.1405±0.0607 (K1), 0.1228±0.0290 (K2), 0.1227±0.0556 (K3). Data showed significant differences of catalase activity between test groups, but showed not significant differences of catalase activity between each groups of Rattus norvegicus strain Wistar’s submandibular gland. In this study concluded decreased catalase activity of Rattus norvegicus strain Wistar’s submandibular gland resulting from x-rays ionizing radiation by 4 times, 8 times and 14 times exposures.


1969 ◽  
Vol 24 (12) ◽  
pp. 1633-1640 ◽  
Author(s):  
F. Stähler ◽  
F. Zywietz ◽  
W. Ewert ◽  
H. A. Künkel

The Relative Biological Efficiency (RBE) of 6-GeV-bremsstrahlung on 3-days-old seedlings of Vicia faba was investigated with the Deutsches ElektronenSynchrotron. Dosimetry was carried out by means of the butanol-sensitized FeII/FeIII-reaction. In a Lucite-phantom we observed an increase of the RBE from 0,65 at the surface to values of about 2 at a depth of 40 cm. As changes of that order of magnitude are doubtless beyond the limits of the maximum experimental error we suppose that production of heavy particles by nuclear reactions such as (γ, n) or (γ, p) in deeper layers of matter might cause an increase of the linear energy transfer of the beam.


1976 ◽  
Vol 54 (7) ◽  
pp. 766-770 ◽  
Author(s):  
S. Radhakrishna ◽  
M. Riggin ◽  
P. W. Whippey ◽  
P. W. M. Jacobs

The thermoluminescence of single crystals of ammonium perchlorate irradiated with X rays, uv light, or high energy electrons has been measured between 80 and 420 K. With a heating rate of 5 K/min. prominent peaks occur at 95, 113, 134, 246, and 320 K; an additional peak is found at 347 K after longer irradiation times. The absorption spectrum of uv-irradiated ammonium perchlorate has also been measured and shows bands at 300, 360, and 610 nm. A comparison of these data with chemical and spectroscopic evidence obtained by other workers has permitted the probable identification of ClO3−, ClO−, ClO2, and F centres as radiation products. Three thermoluminescent peaks remain unassigned.


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