scholarly journals Estimation of Active Compounds Quantity from Pharmaceuticals Based on Ginkgo biloba

Chemosensors ◽  
2020 ◽  
Vol 8 (4) ◽  
pp. 110
Author(s):  
Ramona Oana Gunache (Roșca) ◽  
Constantin Apetrei
Keyword(s):  
Ginkgo Biloba ◽  
Antioxidant Properties ◽  
Electrochemical Determination ◽  
Pharmaceutical Products ◽  
Cyclic Voltammograms ◽  
Redox Processes ◽  
Active Compounds ◽  
Great Utility ◽  
Prescription Product

Ginkgo biloba is one of the most important sources of active compounds, mainly flavonoids and phenolic compounds. Due to its importance related to pharmaceutical practice, the making of a qualitative and quantitative method for the detection and quantification of active compounds from Ginkgo biloba pharmaceutical products is desirable. In this study, the content of biological active compounds from Ginkgo biloba products was estimated using cyclic voltammetry. The electrochemical determination of active compounds was carried out by using a screen-printed carbon electrode modified with carbon nanotubes. The studies regarding parameter optimization were made using solutions containing potassium ferrocyanide and catechol, respectively. In both cases, the redox processes of studied compounds was observed, which were controlled by the diffusion phenomenon. We analyzed two pharmaceutical products containing Ginkgo biloba, a RX product (recipe medicine requires a medical prescription to be dispensed) and an OTC (Over-The-Counter, which can be obtained without a prescription) product. The cyclic voltammograms of the two products showed two redox processes due to the antioxidant properties of the products. It was found that the RX product had a greater content of active compounds compared to the OTC product. Therefore, the voltammetric method has great utility for the determination of compounds with redox properties from pharmaceutical products containing Ginkgo biloba.

Electrochemical determination of antioxidant properties of a series of tetraphenylporphyrin derivatives and their zinc complexes

2015 ◽  
Vol 19 (09) ◽  
pp. 1032-1038 ◽  
Author(s):  
Mariya V. Tesakova ◽  
Aleksandr S. Semeikin ◽  
Vladimir I. Parfenyuk
Keyword(s):  
Antioxidant Capacity ◽  
Antioxidant Properties ◽  
Electrochemical Determination ◽  
Zinc Complexes ◽  
Oh Groups ◽  
Electron Absorption Spectra ◽  
Before And After ◽  
Phenyl Rings ◽  
Effect Of Structure

Zinc complexes of a series of substituted tetraphenylporphyrins containing OH-groups in the phenyl rings were synthesized. Their antioxidant capacity was estimated in reaction of the porphyrins with 2,2′-diphenyl-1-picrylhydrazyl (DPPH) by cyclic voltammetry. The electron absorption spectra of the all synthesized compounds before and after the reaction with 2,2′-diphenyl-1-picrylhydrazyl were recorded. The effect of structure of the porphyrins and zinc complexes on their antioxidant capacity was discussed.

Electrochemical Determination of Vitamin D 3 in Pharmaceutical Products by Using Boron Doped Diamond Electrode

2019 ◽  
Vol 32 (4) ◽  
pp. 741-748
Author(s):  
Ana Đurović ◽  
Zorica Stojanović ◽  
Snežana Kravić ◽  
Jovana Kos ◽  
Lukáš Richtera
Keyword(s):  
Vitamin D ◽  
Electrochemical Determination ◽  
Pharmaceutical Products ◽  
Boron Doped Diamond ◽  
Diamond Electrode ◽  
Boron Doped ◽  
Boron Doped Diamond Electrode ◽  
Vitamin D 3

scholarly journals Investigation into the Antioxidant Activity of Standardized Plant Extracts with Pharmaceutical Potential

2021 ◽  
Vol 11 (18) ◽  
pp. 8685
Author(s):  
Elena Moroșan ◽  
Magdalena Mititelu ◽  
Doina Drăgănescu ◽  
Dumitru Lupuliasa ◽  
Emma Adriana Ozon ◽  
...  
Keyword(s):  
Antioxidant Activity ◽  
Raw Materials ◽  
Antioxidant Properties ◽  
Natural Antioxidants ◽  
Electrochemical Determination ◽  
Pharmaceutical Product ◽  
Plant Raw Materials ◽  
Indirect Evaluation

Given the important role of antioxidants in the cellular degeneration process, as well as the increased interest in recent years related to the use of natural antioxidants in therapy, the present study aims to investigate the antioxidant activity of a new pharmaceutical product containing natural antioxidants extracted from plant raw materials. In a first step, the product conventionally named “CILTAG”, containing a mixture in equal proportions of 10% hydroalcoholic extractive solutions of dried plant raw materials from Medicaginis herba, Trifolii pratense flores, Ginkgo bilobae folium, Myrtilli fructus, and Cynosbati fructus, was obtained. In the second stage, the antioxidant activity of the hydroalcoholic extractive solutions included in the pharmaceutical product was tested by chemiluminescence and electrochemical methods and by the superoxide dismutase (SOD) method. The electrochemical determination of the antioxidant capacity of hydroalcoholic extractive solutions was based on a method that provides an indirect evaluation of the presumed antioxidant properties of some compounds using Trolox (6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid), as a standard measurement. The experimental results indicate a significant antioxidant potential for both the analyzed plant extractive solutions that are part of CILTAG and the final product.

scholarly journals Antioxidant Properties of Green Coffee Extract

Forests ◽  
2020 ◽  
Vol 11 (5) ◽  
pp. 557 ◽  
Author(s):  
Anna Masek ◽  
Malgorzata Latos-Brozio ◽  
Joanna Kałużna-Czaplińska ◽  
Angelina Rosiak ◽  
Ewa Chrzescijanska
Keyword(s):  
Antioxidant Properties ◽  
High Capacity ◽  
Transition Metal Ions ◽  
Electrochemical Determination ◽  
Gas Chromatography Mass Spectrometry ◽  
Potential Range ◽  
Coffee Bean ◽  
Green Coffee ◽  
Vis Spectroscopy

An infusion of green coffee is a commonly consumed beverage, famous for its health-promoting properties. Green coffee owes its properties to the richness of active phytochemicals. The aim of this study was to determine the components of green coffee bean extracts and their properties. The scope of research included gas chromatography-mass spectrometry (GC-MS), Fourier transform infrared spectroscopy (FTIR) and Ultraviolet-Visible spectroscopy (UV-Vis) spectroscopy; the electrochemical determination of the behavior of green coffee extract; and the determination of antioxidant properties by colorimetric spectroscopic methods (ABTS, DPPH, FRAP and CUPRAC). Water and ethanol extracts from green coffee were characterized by significant antioxidant properties and a high capacity to reduce transition metal ions. Voltammetric tests showed that the solution has good antioxidant properties in view of it contains many polyphenolic compounds that oxidize in the potential range tested.

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