scholarly journals CT Texture Analysis Challenges: Influence of Acquisition and Reconstruction Parameters: A Comprehensive Review

Diagnostics ◽  
2020 ◽  
Vol 10 (5) ◽  
pp. 258 ◽  
Author(s):  
Mathilde Espinasse ◽  
Stéphanie Pitre-Champagnat ◽  
Benoit Charmettant ◽  
Francois Bidault ◽  
Andreas Volk ◽  
...  
Keyword(s):  
Medical Imaging ◽  
Texture Analysis ◽  
Prognostic Biomarker ◽  
Published Data ◽  
Medical Field ◽  
Comprehensive Review ◽  
Crucial Step ◽  
Promising Tool ◽  
Voxel Value

Texture analysis in medical imaging is a promising tool that is designed to improve the characterization of abnormal images from patients, to ultimately serve as a predictive or prognostic biomarker. However, the nature of image acquisition itself implies variability in each pixel/voxel value that could jeopardize the usefulness of texture analysis in the medical field. In this review, a search was performed to identify current published data for computed tomography (CT) texture reproducibility and variability. On the basis of this analysis, the critical steps were identified with a view of using texture analysis as a reliable tool in medical imaging. The need to specify the CT scanners used and the associated parameters in published studies is highlighted. Harmonizing acquisition parameters between studies is a crucial step for future texture analysis.

Characterization of Pancreas at Diabetic Patients in CT images using Texture Analysis

2017 ◽  
Vol 7 (7) ◽  
pp. 8
Author(s):  
Mona E. Elbashier ◽  
Suhaib Alameen ◽  
Caroline Edward Ayad ◽  
Mohamed E. M. Gar-Elnabi
Keyword(s):  
Size Distribution ◽  
Texture Analysis ◽  
Classification Accuracy ◽  
Ct Images ◽  
Diabetic Patients ◽  
Gray Level ◽  
Grey Level ◽  
Run Length ◽  
Interactive Data

This study concern to characterize the pancreas areato head, body and tail using Gray Level Run Length Matrix (GLRLM) and extract classification features from CT images. The GLRLM techniques included eleven’s features. To find the gray level distribution in CT images it complements the GLRLM features extracted from CT images with runs of gray level in pixels and estimate the size distribution of thesubpatterns. analyzing the image with Interactive Data Language IDL software to measure the grey level distribution of images. The results show that the Gray Level Run Length Matrix and  features give classification accuracy of pancreashead 89.2%, body 93.6 and the tail classification accuracy 93.5%. The overall classification accuracy of pancreas area 92.0%.These relationships are stored in a Texture Dictionary that can be later used to automatically annotate new CT images with the appropriate pancreas area names.

Problems of species and the features of geographical distribution in colonial volvocine algae (Chlorophyta)

2020 ◽  
Vol 54 (2) ◽  
pp. 299-311
Author(s):  
A. G. Desnitskiy
Keyword(s):  
New Species ◽  
Geographical Distribution ◽  
World Literature ◽  
The Other ◽  
Disjunct Distribution ◽  
Published Data ◽  
Species Problem ◽  
Comprehensive Review ◽  
Volvocine Algae ◽  
Cryptic Taxa

More than ten new species of colonial volvocine algae were described in world literature during recent years. In present review, the published data on taxonomy, geographical distribution and the species problem in this group of algae, mainly from the genera Gonium, Pandorina, Eudorina, and Volvox, are critically discussed. There are both cosmopolitan volvocalean species and species with local or disjunct distribution. On the other hand, the description of new cryptic taxa in some genera of the colonial family Volvocaceae, such as Pandorina and Volvox, complicates the preparation of a comprehensive review on their geography.

scholarly journals MiR-21 in the Cancers of the Digestive System and Its Potential Role as a Diagnostic, Predictive, and Therapeutic Biomarker

Biology ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 417
Author(s):  
Ha Thi Nguyen ◽  
Salah Eddine Oussama Kacimi ◽  
Truc Ly Nguyen ◽  
Kamrul Hassan Suman ◽  
Roselyn Lemus-Martin ◽  
...  
Keyword(s):  
Digestive System ◽  
Potential Role ◽  
Target Genes ◽  
Prognostic Biomarker ◽  
Cancer Biomarkers ◽  
Cancer Biomarker ◽  
Molecular Networks ◽  
Therapeutic Tool ◽  
Comprehensive Review ◽  
Non Coding Rnas

MicroRNAs (miRNAs) are small non-coding RNAs. They can regulate the expression of their target genes, and thus, their dysregulation significantly contributes to the development of cancer. Growing evidence suggests that miRNAs could be used as cancer biomarkers. As an oncogenic miRNA, the roles of miR-21 as a diagnostic and prognostic biomarker, and its therapeutic applications have been extensively studied. In this review, the roles of miR-21 are first demonstrated via its different molecular networks. Then, a comprehensive review on the potential targets and the current applications as a diagnostic and prognostic cancer biomarker and the therapeutic roles of miR-21 in six different cancers in the digestive system is provided. Lastly, a brief discussion on the challenges for the use of miR-21 as a therapeutic tool for these cancers is added.

scholarly journals Drug delivery applications of poly-γ-glutamic acid

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Olalekan A. Balogun-Agbaje ◽  
Olubusola A. Odeniyi ◽  
Michael A. Odeniyi
Keyword(s):  
Drug Delivery ◽  
Glutamic Acid ◽  
Site Characterization ◽  
Fermentation Medium ◽  
Production Optimization ◽  
Main Body ◽  
Crucial Step ◽  
Drug Delivery Application ◽  
Made In

Abstract Background Poly-γ-glutamic acid (γ-PGA) is a biopolymer of microbial origin, consisting of repeating units of l-glutamic acid and/or D-glutamic acid. The biopolymer has found use in the fields of agriculture, food, wastewater, and medicine, owing to its non-toxic, biodegradable, and biocompatible properties. Due to its biodegradability, γ-PGA is being tipped to dislodge synthetic plastics in drug delivery application. High cost of production, relative to plastics, is however a clog in the wheel of achieving this. Main body of abstract This review looked at the production, nanoparticles fabrication, and drug delivery application of γ-PGA. γ-PGA production optimization by modifying the fermentation medium to tailor towards the production of desirable polymer at reduced cost and techniques for the formulation of γ-PGA nanoparticle as well as its characterization were discussed. This review also evaluated the application of γ-PGA and its nanoparticles in the delivery of drugs to action site. Characterization of γ-PGA and its nanoparticles is a crucial step towards determining the applicability of the biopolymer. γ-PGA has been used in the delivery of active agents to action sites. Conclusion This review highlights some of the efforts that have been made in the appraisal of γ-PGA and its nanoparticles for drug delivery. γ-PGA is a candidate for future extensive use in drug delivery.

Development of a prototype for modelling soil–pipe interaction and its application for predicting uplift resistance to buried pipe movements in sand

2018 ◽  
Vol 55 (10) ◽  
pp. 1451-1474 ◽  
Author(s):  
Yousef Ansari ◽  
George Kouretzis ◽  
Scott W. Sloan
Keyword(s):  
Scale Effects ◽  
Reaction Force ◽  
Failure Surface ◽  
Relative Displacement ◽  
Published Data ◽  
Buried Pipe ◽  
Image Velocimetry ◽  
Close Range ◽  
Uplift Resistance

This paper presents a testing rig for measuring the reactions on rigid pipes buried in sand during episodes of relative displacement. Following a detailed presentation of the 1g prototype, the test preparation procedure, and the characterization of the test sand’s shear strength and dilation potential under the low confining stresses pertinent to the problem, the paper focuses on the workflow devised to obtain accurate measurements of friction and arching effects, and accordingly normalize them to account for scale (stress level) effects. Emphasis is put on demonstrating the effectiveness of the sand deposition method for accurately controlling the density of the sample, and on quantitatively assessing its uniformity. Measurements obtained during a series of uplift tests, including reaction force – pipe displacement curves and images of the developing failure surface, facilitated by particle image velocimetry and close-range photogrammetry techniques, are compared against published data and analytical methods. The results lead to the development of a new simplified formula for calculating the uplift resistance to buried pipe movements in sand: capable of accounting for scale effects, yet simple enough to be used for the analysis of pipes in practice.

Mo2055 Efficacy and Safety of the Over-the-Scope-Clip Device: A Comprehensive Review of Published Data

2016 ◽  
Vol 83 (5) ◽  
pp. AB511-AB512
Author(s):  
Sayf A. Bala ◽  
Vivek Kaul ◽  
Truptesh H. Kothari ◽  
Shivangi Kothari
Keyword(s):  
Published Data ◽  
Efficacy And Safety ◽  
Comprehensive Review ◽  
Over The Scope Clip

Characterization of micrographs and fractographs of Cu-strengthened HSLA steel using image texture analysis

Measurement ◽  
2014 ◽  
Vol 47 ◽  
pp. 130-144 ◽  
Author(s):  
Samik Dutta ◽  
Kaustav Barat ◽  
Arpan Das ◽  
Swapan Kumar Das ◽  
A.K. Shukla ◽  
...  
Keyword(s):  
Texture Analysis ◽  
Hsla Steel ◽  
Image Texture ◽  
Image Texture Analysis

Characterization of Porosity and Pore Size Distribution Changes in Human Compact Bone by Low-Field NMR

2000 ◽  
Author(s):  
Qingwen Ni ◽  
J. Derwin King ◽  
Xiaodu Wang
Keyword(s):  
Mechanical Strength ◽  
Compact Bone ◽  
Biomechanical Properties ◽  
Spongy Bone ◽  
Comprehensive Review ◽  
Low Field ◽  
Human Compact Bone ◽  
Direct Sensing ◽  
Low Field Nmr

Abstract Previous studies have shown that the overall porosity of bone has a significant effect on the mechanical strength of bone. In a comprehensive review on porosity of bone, Martin [1] described that small changes in porosity would lead to significant changes in the stiffness and strength of both compact and spongy bone. In a recently study, McCalden [2], reported that the porosity of bone has a significant effect to absorb energy during fracture. Since changes in numbers and sizes of these natural cavities are directly related to the remodeling processes and biomechanical properties of bone, a direct sensing technique to detect such changes in bone has been long wanted.

scholarly journals Design and Biophysical Characterization of Poly (l-Lactic) Acid Microcarriers with and without Modification of Chitosan and Nanohydroxyapatite

Polymers ◽  
2018 ◽  
Vol 10 (10) ◽  
pp. 1061 ◽  
Author(s):  
Liying Li ◽  
Kedong Song ◽  
Yongzhi Chen ◽  
Yiwei Wang ◽  
Fangxin Shi ◽  
...  
Keyword(s):  
Tissue Engineering ◽  
Cell Culture ◽  
Lactic Acid ◽  
Average Diameter ◽  
Natural Polymers ◽  
Promoting Effect ◽  
Biophysical Characterization ◽  
Promising Tool ◽  
Cell Carrier

Nowadays, microcarriers are widely utilized in drug delivery, defect filling, and cell culture. Also, many researchers focus on the combination of synthetic and natural polymers and bioactive ceramics to prepare composite biomaterials for tissue engineering and regeneration. In this study, three kinds of microcarriers were prepared based on physical doping and surface modification, named Poly (l-lactic) acid (PLLA), PLLA/nanohydroxyapatite (PLLA/nHA), and PLLA/nHA/Chitosan (PLLA/nHA/Ch). The physicochemical properties of the microcarriers and their functional performances in MC3T3-E1 cell culture were compared. Statistical results showed that the average diameter of PLLA microcarriers was 291.9 ± 30.7 μm, and that of PLLA/nHA and PLLA/nHA/Ch microcarriers decreased to 275.7 ± 30.6 μm and 269.4 ± 26.3 μm, respectively. The surface roughness and protein adsorption of microcarriers were enhanced with the doping of nHA and coating of chitosan. The cell-carrier cultivation stated that the PLLA/nHA microcarriers had the greatest proliferation-promoting effect, while the PLLA/nHA/Ch microcarriers performed the strongest attachment with MC3T3-E1 cells. Besides, the cells on the PLLA/nHA/Ch microcarriers exhibited optimal osteogenic expression. Generally, chitosan was found to improve microcarriers with superior characteristics in cell adhesion and differentiation, and nanohydroxyapatite was beneficial for microcarriers regarding sphericity and cell proliferation. Overall, the modified microcarriers may be considered as a promising tool for bone tissue engineering.

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