scholarly journals A Deep Neural Network for Early Detection and Prediction of Chronic Kidney Disease

Diagnostics ◽  
2022 ◽  
Vol 12 (1) ◽  
pp. 116
Author(s):  
Vijendra Singh ◽  
Vijayan K. Asari ◽  
Rajkumar Rajasekaran
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Early Detection ◽  
Deep Neural Network ◽  
Missing Values ◽  
Machine Learning Techniques ◽  
Recursive Feature Elimination ◽  
Support Vector

Diabetes and high blood pressure are the primary causes of Chronic Kidney Disease (CKD). Glomerular Filtration Rate (GFR) and kidney damage markers are used by researchers around the world to identify CKD as a condition that leads to reduced renal function over time. A person with CKD has a higher chance of dying young. Doctors face a difficult task in diagnosing the different diseases linked to CKD at an early stage in order to prevent the disease. This research presents a novel deep learning model for the early detection and prediction of CKD. This research objectives to create a deep neural network and compare its performance to that of other contemporary machine learning techniques. In tests, the average of the associated features was used to replace all missing values in the database. After that, the neural network’s optimum parameters were fixed by establishing the parameters and running multiple trials. The foremost important features were selected by Recursive Feature Elimination (RFE). Hemoglobin, Specific Gravity, Serum Creatinine, Red Blood Cell Count, Albumin, Packed Cell Volume, and Hypertension were found as key features in the RFE. Selected features were passed to machine learning models for classification purposes. The proposed Deep neural model outperformed the other four classifiers (Support Vector Machine (SVM), K-Nearest Neighbor (KNN), Logistic regression, Random Forest, and Naive Bayes classifier) by achieving 100% accuracy. The proposed approach could be a useful tool for nephrologists in detecting CKD.

scholarly journals Survey for the Prediction of Chronic Kidney Disease using Machine Learning

2019 ◽  
pp. 154-158
Author(s):  
Pooja Sharma ◽  
Saket J Swarndeep
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Kidney Diseases ◽  
Detection System ◽  
Machine Learning Techniques ◽  
Network System ◽  
Data Set ◽  
Neural Network System

According the 2010 global burden of disease study, Chronic Kidney Diseases (CKD) was ranked 18th in the list of causes of total no. of deaths worldwide. 10% of the population worldwide is affected by CKD. The prediction of CKD can become a boon for the population to predict the health. Various method and techniques are undergoing the research phase for developing the most accurate CKD prediction system. Using Machine Learning techniques is the most promising one in this area due to its computing function and Machine Learning rules. Existing Systems are working well in predicting the accurate result but still more attributes of data and complicity of health parameter make the root layer for the innovation of new approaches. This study focuses on a novel approach for improving the prediction of CKD. In recent time Neural network system has discovered its use in disease diagnoses, which is depended upon prediction from symptoms data set. Chronic kidney disease detection system using neural network is shown here. This system of neural network accepts disease-symptoms as input and it is trained according to various training algorithms. After neural network is trained using back propagation algorithms, this trained neural network system is used for detection of kidney disease in the human body.

scholarly journals Diagnosis of Chronic Kidney Disease Using Effective Classification Algorithms and Recursive Feature Elimination Techniques

2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Ebrahime Mohammed Senan ◽  
Mosleh Hmoud Al-Adhaileh ◽  
Fawaz Waselallah Alsaade ◽  
Theyazn H. H. Aldhyani ◽  
Ahmed Abdullah Alqarni ◽  
...  
Keyword(s):  
Chronic Kidney Disease ◽  
Random Forest ◽  
Kidney Disease ◽  
Early Diagnosis ◽  
Kidney Diseases ◽  
Adult Population ◽  
Machine Learning Techniques ◽  
Recursive Feature Elimination ◽  
Support Vector ◽  
Classification Algorithms

Chronic kidney disease (CKD) is among the top 20 causes of death worldwide and affects approximately 10% of the world adult population. CKD is a disorder that disrupts normal kidney function. Due to the increasing number of people with CKD, effective prediction measures for the early diagnosis of CKD are required. The novelty of this study lies in developing the diagnosis system to detect chronic kidney diseases. This study assists experts in exploring preventive measures for CKD through early diagnosis using machine learning techniques. This study focused on evaluating a dataset collected from 400 patients containing 24 features. The mean and mode statistical analysis methods were used to replace the missing numerical and the nominal values. To choose the most important features, Recursive Feature Elimination (RFE) was applied. Four classification algorithms applied in this study were support vector machine (SVM), k-nearest neighbors (KNN), decision tree, and random forest. All the classification algorithms achieved promising performance. The random forest algorithm outperformed all other applied algorithms, reaching an accuracy, precision, recall, and F1-score of 100% for all measures. CKD is a serious life-threatening disease, with high rates of morbidity and mortality. Therefore, artificial intelligence techniques are of great importance in the early detection of CKD. These techniques are supportive of experts and doctors in early diagnosis to avoid developing kidney failure.

Big Data to Knowledge: Application of Machine Learning to Predictive Modeling of Therapeutic Response in Cancer.

2020 ◽  
Vol 21 ◽  
Author(s):  
Sukanya Panja ◽  
Sarra Rahem ◽  
Cassandra J. Chu ◽  
Antonina Mitrofanova
Keyword(s):  
Machine Learning ◽  
Missing Values ◽  
Therapeutic Response ◽  
Patient Data ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Complex Data ◽  
Human Machine Interaction ◽  
Data Repositories ◽  
Response Modeling

Background: In recent years, the availability of high throughput technologies, establishment of large molecular patient data repositories, and advancement in computing power and storage have allowed elucidation of complex mechanisms implicated in therapeutic response in cancer patients. The breadth and depth of such data, alongside experimental noise and missing values, requires a sophisticated human-machine interaction that would allow effective learning from complex data and accurate forecasting of future outcomes, ideally embedded in the core of machine learning design. Objective: In this review, we will discuss machine learning techniques utilized for modeling of treatment response in cancer, including Random Forests, support vector machines, neural networks, and linear and logistic regression. We will overview their mathematical foundations and discuss their limitations and alternative approaches all in light of their application to therapeutic response modeling in cancer. Conclusion: We hypothesize that the increase in the number of patient profiles and potential temporal monitoring of patient data will define even more complex techniques, such as deep learning and causal analysis, as central players in therapeutic response modeling.

scholarly journals Burst Pressure Prediction of API 5L X-Grade Dented Pipelines Using Deep Neural Network

2020 ◽  
Vol 8 (10) ◽  
pp. 766
Author(s):  
Dohan Oh ◽  
Julia Race ◽  
Selda Oterkus ◽  
Bonguk Koo
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Artificial Neural Network ◽  
Network Model ◽  
Neural Network Model ◽  
Deep Neural Network ◽  
Machine Learning Techniques ◽  
Burst Pressure ◽  
Comparison Results ◽  
Artificial Neural

Mechanical damage is recognized as a problem that reduces the performance of oil and gas pipelines and has been the subject of continuous research. The artificial neural network in the spotlight recently is expected to be another solution to solve the problems relating to the pipelines. The deep neural network, which is on the basis of artificial neural network algorithm and is a method amongst various machine learning methods, is applied in this study. The applicability of machine learning techniques such as deep neural network for the prediction of burst pressure has been investigated for dented API 5L X-grade pipelines. To this end, supervised learning is employed, and the deep neural network model has four layers with three hidden layers, and the neural network uses the fully connected layer. The burst pressure computed by deep neural network model has been compared with the results of finite element analysis based parametric study, and the burst pressure calculated by the experimental results. According to the comparison results, it showed good agreement. Therefore, it is concluded that deep neural networks can be another solution for predicting the burst pressure of API 5L X-grade dented pipelines.

Using Machine Learning to Identify Metabolomic Signatures of Pediatric Chronic Kidney Disease Etiology

2022 ◽  
pp. ASN.2021040538
Author(s):  
Arthur M. Lee ◽  
Jian Hu ◽  
Yunwen Xu ◽  
Alison G. Abraham ◽  
Rui Xiao ◽  
...  
Keyword(s):  
Machine Learning ◽  
Chronic Kidney Disease ◽  
Kidney Disease ◽  
Gut Microbiome ◽  
Support Vector ◽  
Pathway Enrichment Analysis ◽  
Disease Etiology ◽  
Content Type ◽  
Extreme Gradient Boosting ◽  
Pediatric Ckd

BackgroundUntargeted plasma metabolomic profiling combined with machine learning (ML) may lead to discovery of metabolic profiles that inform our understanding of pediatric CKD causes. We sought to identify metabolomic signatures in pediatric CKD based on diagnosis: FSGS, obstructive uropathy (OU), aplasia/dysplasia/hypoplasia (A/D/H), and reflux nephropathy (RN).MethodsUntargeted metabolomic quantification (GC-MS/LC-MS, Metabolon) was performed on plasma from 702 Chronic Kidney Disease in Children study participants (n: FSGS=63, OU=122, A/D/H=109, and RN=86). Lasso regression was used for feature selection, adjusting for clinical covariates. Four methods were then applied to stratify significance: logistic regression, support vector machine, random forest, and extreme gradient boosting. ML training was performed on 80% total cohort subsets and validated on 20% holdout subsets. Important features were selected based on being significant in at least two of the four modeling approaches. We additionally performed pathway enrichment analysis to identify metabolic subpathways associated with CKD cause.ResultsML models were evaluated on holdout subsets with receiver-operator and precision-recall area-under-the-curve, F1 score, and Matthews correlation coefficient. ML models outperformed no-skill prediction. Metabolomic profiles were identified based on cause. FSGS was associated with the sphingomyelin-ceramide axis. FSGS was also associated with individual plasmalogen metabolites and the subpathway. OU was associated with gut microbiome–derived histidine metabolites.ConclusionML models identified metabolomic signatures based on CKD cause. Using ML techniques in conjunction with traditional biostatistics, we demonstrated that sphingomyelin-ceramide and plasmalogen dysmetabolism are associated with FSGS and that gut microbiome–derived histidine metabolites are associated with OU.

scholarly journals Estimating Forest Carbon Fluxes Using Machine Learning Techniques Based on Eddy Covariance Measurements

2018 ◽  
Vol 10 (1) ◽  
pp. 203 ◽  
Author(s):  
Xianming Dou ◽  
Yongguo Yang ◽  
Jinhui Luo
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Eddy Covariance ◽  
Carbon Flux ◽  
Carbon Fluxes ◽  
Forest Carbon ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Inference System ◽  
Learning Techniques

Approximating the complex nonlinear relationships that dominate the exchange of carbon dioxide fluxes between the biosphere and atmosphere is fundamentally important for addressing the issue of climate change. The progress of machine learning techniques has offered a number of useful tools for the scientific community aiming to gain new insights into the temporal and spatial variation of different carbon fluxes in terrestrial ecosystems. In this study, adaptive neuro-fuzzy inference system (ANFIS) and generalized regression neural network (GRNN) models were developed to predict the daily carbon fluxes in three boreal forest ecosystems based on eddy covariance (EC) measurements. Moreover, a comparison was made between the modeled values derived from these models and those of traditional artificial neural network (ANN) and support vector machine (SVM) models. These models were also compared with multiple linear regression (MLR). Several statistical indicators, including coefficient of determination (R2), Nash-Sutcliffe efficiency (NSE), bias error (Bias) and root mean square error (RMSE) were utilized to evaluate the performance of the applied models. The results showed that the developed machine learning models were able to account for the most variance in the carbon fluxes at both daily and hourly time scales in the three stands and they consistently and substantially outperformed the MLR model for both daily and hourly carbon flux estimates. It was demonstrated that the ANFIS and ANN models provided similar estimates in the testing period with an approximate value of R2 = 0.93, NSE = 0.91, Bias = 0.11 g C m−2 day−1 and RMSE = 1.04 g C m−2 day−1 for daily gross primary productivity, 0.94, 0.82, 0.24 g C m−2 day−1 and 0.72 g C m−2 day−1 for daily ecosystem respiration, and 0.79, 0.75, 0.14 g C m−2 day−1 and 0.89 g C m−2 day−1 for daily net ecosystem exchange, and slightly outperformed the GRNN and SVM models. In practical terms, however, the newly developed models (ANFIS and GRNN) are more robust and flexible, and have less parameters needed for selection and optimization in comparison with traditional ANN and SVM models. Consequently, they can be used as valuable tools to estimate forest carbon fluxes and fill the missing carbon flux data during the long-term EC measurements.

Traditional versus Neural Network Classification Methods for Facial Emotion Recognition

2021 ◽  
Vol 7 (2) ◽  
pp. 203-206
Author(s):  
Herag Arabian ◽  
Verena Wagner-Hartl ◽  
Knut Moeller
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Emotion Recognition ◽  
Network Architecture ◽  
Autism Spectrum ◽  
Facial Emotion Recognition ◽  
Facial Emotion ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Machine Model

Abstract Facial emotion recognition (FER) is a topic that has gained interest over the years for its role in bridging the gap between Human and Machine interactions. This study explores the potential of real time FER modelling, to be integrated in a closed loop system, to help in treatment of children suffering from Autism Spectrum Disorder (ASD). The aim of this study is to show the differences between implementing Traditional machine learning and Deep learning approaches for FER modelling. Two classification approaches were taken, the first approach was based on classic machine learning techniques using Histogram of Oriented Gradients (HOG) for feature extraction, with a k-Nearest Neighbor and a Support Vector Machine model as classifiers. The second approach uses Transfer Learning based on the popular “Alex Net” Neural Network architecture. The performance of the approaches was based on the accuracy of randomly selected validation sets after training on random training sets of the Oulu-CASIA database. The data analyzed shows that traditional machine learning methods are as effective as deep neural net models and are a good compromise between accuracy, extracted features, computational speed and costs.

scholarly journals Roundness prediction in centreless grinding using physics-enhanced machine learning techniques

2020 ◽  
Author(s):  
Hossein Safarzadeh ◽  
Marco Leonesio ◽  
Giacomo Bianchi ◽  
Michele Monno
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Regression Model ◽  
Hybrid Models ◽  
Physical Models ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Grinding Wheel ◽  
Wheel Wear ◽  
Learning Techniques

AbstractThis work proposes a model for suggesting optimal process configuration in plunge centreless grinding operations. Seven different approaches were implemented and compared: first principles model, neural network model with one hidden layer, support vector regression model with polynomial kernel function, Gaussian process regression model and hybrid versions of those three models. The first approach is based on an enhancement of the well-known numerical process simulation of geometrical instability. The model takes into account raw workpiece profile and possible wheel-workpiece loss of contact, which introduces an inherent limitation on the resulting profile waviness. Physical models, because of epistemic errors due to neglected or oversimplified functional relationships, can be too approximated for being considered in industrial applications. Moreover, in deterministic models, uncertainties affecting the various parameters are not explicitly considered. Complexity in centreless grinding models arises from phenomena like contact length dependency on local compliance, contact force and grinding wheel roughness, unpredicted material properties of the grinding wheel and workpiece, precision of the manual setup done by the operator, wheel wear and nature of wheel wear. In order to improve the overall model prediction accuracy and allow automated continuous learning, several machine learning techniques have been investigated: a Bayesian regularized neural network, an SVR model and a GPR model. To exploit the a priori knowledge embedded in physical models, hybrid models are proposed, where neural network, SVR and GPR models are fed by the nominal process parameters enriched with the roundness predicted by the first principle model. Those hybrid models result in an improved prediction capability.

scholarly journals A Machine Learning View on Momentum and Reversal Trading

Algorithms ◽  
2018 ◽  
Vol 11 (11) ◽  
pp. 170 ◽  
Author(s):  
Zhixi Li ◽  
Vincent Tam
Keyword(s):  
Neural Network ◽  
Machine Learning ◽  
Stock Market ◽  
Short Term Memory ◽  
Predictive Ability ◽  
Trading Strategies ◽  
Machine Learning Techniques ◽  
Support Vector ◽  
Learning Approaches ◽  
Learning Techniques

Momentum and reversal effects are important phenomena in stock markets. In academia, relevant studies have been conducted for years. Researchers have attempted to analyze these phenomena using statistical methods and to give some plausible explanations. However, those explanations are sometimes unconvincing. Furthermore, it is very difficult to transfer the findings of these studies to real-world investment trading strategies due to the lack of predictive ability. This paper represents the first attempt to adopt machine learning techniques for investigating the momentum and reversal effects occurring in any stock market. In the study, various machine learning techniques, including the Decision Tree (DT), Support Vector Machine (SVM), Multilayer Perceptron Neural Network (MLP), and Long Short-Term Memory Neural Network (LSTM) were explored and compared carefully. Several models built on these machine learning approaches were used to predict the momentum or reversal effect on the stock market of mainland China, thus allowing investors to build corresponding trading strategies. The experimental results demonstrated that these machine learning approaches, especially the SVM, are beneficial for capturing the relevant momentum and reversal effects, and possibly building profitable trading strategies. Moreover, we propose the corresponding trading strategies in terms of market states to acquire the best investment returns.

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