scholarly journals Voronoi Decomposition of Cardiovascular Dependency Structures in Different Ambient Conditions: An Entropy Study

Entropy ◽  
2019 ◽  
Vol 21 (11) ◽  
pp. 1103 ◽  
Author(s):  
Bajic ◽  
Skoric ◽  
Milutinovic-Smiljanic ◽  
Japundzic-Zigon

This paper proposes a method that maps the coupling strength of an arbitrary number of signals D, D ≥ 2, into a single time series. It is motivated by the inability of multiscale entropy to jointly analyze more than two signals. The coupling strength is determined using the copula density defined over a [0 1]D copula domain. The copula domain is decomposed into the Voronoi regions, with volumes inversely proportional to the dependency level (coupling strength) of the observed joint signals. A stream of dependency levels, ordered in time, creates a new time series that shows the fluctuation of the signals’ coupling strength along the time axis. The composite multiscale entropy (CMSE) is then applied to three signals, systolic blood pressure (SBP), pulse interval (PI), and body temperature (tB), simultaneously recorded from rats exposed to different ambient temperatures (tA). The obtained results are consistent with the results from the classical studies, and the method itself offers more levels of freedom than the classical analysis.

Author(s):  
Marko Mozetić ◽  
Tamara Škorić ◽  
Jelena Antelj ◽  
Katarina Otašević ◽  
Branislav Milovanović ◽  
...  

Portapres® is a unique device that reliably accomplishes a challenging task of continuous and non-invasive recording ofblood pressure (BP) waveforms in moving subjects. The complex procedure of Portapres® signal acquisition includes periodic changesof cuffed fingers to avoid pain and stress, as well as the blood pressure correction due to the increasing and decreasing elevation of armposture. Due to these procedures, the recorded waveforms are corrupted. The aim of this paper is to analyze the influence of inevitableartifacts on parameters obtained from the blood pressure waveforms. The analyzed waveforms are obtained from healthy volunteers atBezanija Kosa Hospital, Belgrade. The parameters include systolic blood pressure (SBP) and pulse interval (PI) extracted byBeatscope® software. The interrelationship of SBP and PI signals forms a major cardiovascular feedback – baroreflex. It can beanalyzed using the sequence method for spontaneous baroreflex sensitivity, but the tools that reveal more profound dependencystructures include cross-approximate and cross-sample entropy, as well as the copula structures. The influence of artifacts, inevitable inPortapres® signals, is the main goal of this study. The analyses revealed that automatic artifact correction induced no significantchanges considering the statistical moments and the baroreflex sensitivity; the same applies to the copula density and rank tests. Theentropy analysis, however, turned out to be extremely sensitive so its implementation in Portapres® signal analysis is not recommended.


Author(s):  
M. Trupiano ◽  
S. Aarabi ◽  
A. F. Emery

The use of a tourniquet leads to nerve damage, even if applied for short periods of time. This damage can be minimized if the limb is cooled. Because of the low conductivities of human tissue, core limb cooling is slow unless the surface temperature is very cool. Subzero surface temperatures can lead to skin injury (i.e., frostbite). Ideally one would adjust the limb surface temperatures as a function of time to maximize the cooling rate while avoiding permanent tissue damage. One possible approach is to use a thermoelectric cooler (TEC) in conjunction with a programmable power supply. TEC performance varies strongly with heat absorption rate, a function of limb thermal properties, and hot side temperatures that are strongly affected by the surface conditions on the hot side, i.e., overall heat transfer coefficients and ambient conditions. The paper describes the use of finite element simulation to predict the usefulness of using thermoelectric coolers applied to the surface of a limb when compared to the standard approach of using ice packs. Since the TEC performance is strongly influenced by its warm side thermal conditions, experimental results are presented for different ambient temperatures, free and forced convection, and evaporation of water from a wickable covering.


2017 ◽  
Vol 2017 ◽  
pp. 1-17 ◽  
Author(s):  
Tatjana Tasic ◽  
Sladjana Jovanovic ◽  
Omer Mohamoud ◽  
Tamara Skoric ◽  
Nina Japundzic-Zigon ◽  
...  

Objectives. This paper analyses temporal dependency in the time series recorded from aging rats, the healthy ones and those with early developed hypertension. The aim is to explore effects of age and hypertension on mutual sample relationship along the time axis.Methods. A copula method is applied to raw and to differentially coded signals. The latter ones were additionally binary encoded for a joint conditional entropy application. The signals were recorded from freely moving male Wistar rats and from spontaneous hypertensive rats, aged 3 months and 12 months.Results. The highest level of comonotonic behavior of pulse interval with respect to systolic blood pressure is observed at time lagsτ=0, 3, and 4, while a strong counter-monotonic behavior occurs at time lagsτ=1and 2.Conclusion. Dynamic range of aging rats is considerably reduced in hypertensive groups. Conditional entropy of systolic blood pressure signal, compared to unconditional, shows an increased level of discrepancy, except for a time lag 1, where the equality is preserved in spite of the memory of differential coder. The antiparallel streams play an important role at single beat time lag.


Entropy ◽  
2019 ◽  
Vol 21 (10) ◽  
pp. 1024 ◽  
Author(s):  
Estelle Blons ◽  
Laurent Arsac ◽  
Pierre Gilfriche ◽  
Veronique Deschodt-Arsac

In humans, physiological systems involved in maintaining stable conditions for health and well-being are complex, encompassing multiple interactions within and between system components. This complexity is mirrored in the temporal structure of the variability of output signals. Entropy has been recognized as a good marker of systems complexity, notably when calculated from heart rate and postural dynamics. A degraded entropy is generally associated with frailty, aging, impairments or diseases. In contrast, high entropy has been associated with the elevated capacity to adjust to an ever-changing environment, but the link is unknown between entropy and the capacity to cope with cognitive tasks in a healthy young to middle-aged population. Here, we addressed classic markers (time and frequency domains) and refined composite multiscale entropy (MSE) markers (after pre-processing) of heart rate and postural sway time series in 34 participants during quiet versus cognitive task conditions. Recordings lasted 10 min for heart rate and 51.2 s for upright standing, providing time series lengths of 500–600 and 2048 samples, respectively. The main finding was that entropy increased during cognitive tasks. This highlights the possible links between our entropy measures and the systems complexity that probably facilitates a control remodeling and a flexible adaptability in our healthy participants. We conclude that entropy is a reliable marker of neurophysiological complexity and adaptability in autonomic and somatic systems.


2020 ◽  
Vol 68 ◽  
pp. 97-122
Author(s):  
Jean-Marc Bardet ◽  
Vincent Brault ◽  
Serguei Dachian ◽  
Farida Enikeeva ◽  
Bruno Saussereau

Recent contributions to change-point detection, segmentation and inference for non-regular models are presented. Various problems are considered including the multiple change-point estimation with adaptive penalty for time series with different dependency structures, estimation of the singularity point in cusp-type models, inference for thresholded autoregressive models, and cross-segmentation of matrices.


Energies ◽  
2019 ◽  
Vol 12 (16) ◽  
pp. 3125 ◽  
Author(s):  
Yuan ◽  
Lin ◽  
Mao ◽  
Li ◽  
Yang ◽  
...  

This study presents the development and evaluation of a novel partially open-loop heat pump dryer with a unit-room (HPDU). The unit-room was designed to enable the ambient air to be mixed with the return air, thereby reducing the influence of the ambient air on the system performance, while maintaining a high system thermal efficiency. A modelling system for the HPDU was developed and validated based on a real-scale experimental study. By using the modelling system, the system characteristics under different ambient conditions and bypass factors were analyzed. The energy benefit of the proposed HPDU was quantified through a comparative study with a closed-loop heat pump dryer (CHPD). It is evident that a maximal specific moisture extraction rate (SMER) and a minimal total energy consumption (TEC) existed when changing the bypass factor of the HPDU under certain ambient temperatures. Compared to the CHPD, the coefficient of performance (COP) of the HPDU increased by up to 39.56%, presenting a significant energy benefit for the application of HPDU.


Entropy ◽  
2020 ◽  
Vol 22 (9) ◽  
pp. 1042 ◽  
Author(s):  
Mirjana M. Platiša ◽  
Nikola N. Radovanović ◽  
Aleksandar Kalauzi ◽  
Goran Milašinović ◽  
Siniša U. Pavlović

It is known that in pathological conditions, physiological systems develop changes in the multiscale properties of physiological signals. However, in real life, little is known about how changes in the function of one of the two coupled physiological systems induce changes in function of the other one, especially on their multiscale behavior. Hence, in this work we aimed to examine the complexity of cardio-respiratory coupled systems control using multiscale entropy (MSE) analysis of cardiac intervals MSE (RR), respiratory time series MSE (Resp), and synchrony of these rhythms by cross multiscale entropy (CMSE) analysis, in the heart failure (HF) patients and healthy subjects. We analyzed 20 min of synchronously recorded RR intervals and respiratory signal during relaxation in the supine position in 42 heart failure patients and 14 control healthy subjects. Heart failure group was divided into three subgroups, according to the RR interval time series characteristics (atrial fibrillation (HFAF), sinus rhythm (HFSin), and sinus rhythm with ventricular extrasystoles (HFVES)). Compared with healthy control subjects, alterations in respiratory signal properties were observed in patients from the HFSin and HFVES groups. Further, mean MSE curves of RR intervals and respiratory signal were not statistically different only in the HFSin group (p = 0.43). The level of synchrony between these time series was significantly higher in HFSin and HFVES patients than in control subjects and HFAF patients (p < 0.01). In conclusion, depending on the specific pathologies, primary alterations in the regularity of cardiac rhythm resulted in changes in the regularity of the respiratory rhythm, as well as in the level of their asynchrony.


2005 ◽  
Vol 119 (2) ◽  
pp. 159
Author(s):  
Todd N. Zimmerling

I investigated den type selection by Porcupines (Erethizon dorsatum), in relation to the thermal cover provided by the den type, over a period of four winters. Porcupines used log dens, stump dens and rock dens in proportion to the thermal cover provided by each den type. Based on behavioural observations of Porcupines, I assumed that the lower critical temperature for porcupines in my study area was -4°C. Both stump and rock dens provided adequate thermal protection, under most ambient conditions, to allow Porcupines to maintain their body temperature, without increasing basal metabolic rate. In most cases rock and stump dens maintained den temperatures above -4°C until ambient temperatures reached -12°C or lower. In contrast log dens provided poor thermal protection, even in years of thick snowcover. When ambient temperatures dropped below -4°C, den temperatures within log dens were also recorded below -4°C. Log dens were used least often by Porcupines, whereas stump and rock dens were used most often. Despite the large number of potential dens available to Porcupines within the study area, den use was generally limited to three dens per porcupine per winter. The limited use of dens by an individual porcupine during winter may be related to the energetic cost of finding a new den or it may be related to specific selection criteria used by Porcupines.


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