scholarly journals Hardware in the Loop Implementation of the Oscillator-based Heart Model: A Framework for Testing Medical Devices

Electronics ◽  
2020 ◽  
Vol 9 (4) ◽  
pp. 571
Author(s):  
Chiara Di Mascio ◽  
Giambattista Gruosso

The hardware in the loop technologies allow to simulate physical models in combination with real devices in order to validate the behavior of the latter under different conditions, not easily reproducible in the real world. They are widely used in various industrial applications. In this work we want to extend the methodology to medical devices. These must interact with the patient to obtain the desired clinical result, however, during the development and validation phase of medical devices, the patient cannot be involved in the testing process. In this article the hardware in the loop methodology is proposed starting from a mathematical model of the heart, based on oscillators, that can be used to validate pacemakers or other medical devices.

2016 ◽  
Vol 01 (03) ◽  
pp. 1640008 ◽  
Author(s):  
Maryna Kvasnytsia ◽  
Nele Famaey ◽  
Michal Böhm ◽  
Eva Verhoelst

Using realistic benchtop models in early stages of device development can reduce time and efforts necessary to move the device to further testing. In this study, we propose several patient specific vascular benchtop models for the development and validation of a robotic catheter for transcatheter aortic valve implantation. The design and manufacturing of these models, and their properties are presented. Additionally, it is demonstrated that the described design process provides virtual models that are accurately linked to the physical models.


2002 ◽  
Vol 7 (5) ◽  
pp. 274-278
Author(s):  
Ellen Hines

Functions are an important component in the study of mathematics (NCTM 1989, 2000). Learning about the concept of functions can be a natural way for students to “mathematize” the real-world relationships that they observe. Everyday life abounds with opportunities for students to observe and describe dynamic relationships that can be classified as functions.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Xia-Xia Zhao ◽  
Jian-Zhong Wang

Information plays an important role in modern society. In this paper, we presented a mathematical model of information spreading with isolation. It was found that such a model has rich dynamics including Hopf bifurcation. The results showed that, for a wide range of parameters, there is a bistable phenomenon in the process of information spreading and thus the information cannot be well controlled. Moreover, the model has a limit cycle which implies that the information exhibits periodic outbreak which is consistent with the observations in the real world.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
V. R. Sanal Kumar ◽  
Vigneshwaran Sankar ◽  
Nichith Chandrasekaran ◽  
Sulthan Ariff Rahman Mohamed Rafic ◽  
Ajith Sukumaran ◽  
...  

AbstractEvidences are escalating on the diverse neurological-disorders and asymptomatic cardiovascular-diseases associated with COVID-19 pandemic due to the Sanal-flow-choking. Herein, we established the proof of the concept of nanoscale Sanal-flow-choking in real-world fluid-flow systems using a closed-form-analytical-model. This mathematical-model is capable of predicting exactly the 3D-boundary-layer-blockage factor of nanoscale diabatic-fluid-flow systems (flow involves the transfer of heat) at the Sanal-flow-choking condition. As the pressure of the diabatic nanofluid and/or non-continuum-flows rises, average-mean-free-path diminishes and thus, the Knudsen-number lowers heading to a zero-slip wall-boundary condition with the compressible-viscous-flow regime in the nanoscale-tubes leading to Sanal-flow-choking due to the sonic-fluid-throat effect. At the Sanal-flow-choking condition the total-to-static pressure ratio (ie., systolic-to-diastolic pressure ratio) is a unique function of the heat-capacity-ratio of the real-world flows. The innovation of the nanoscale Sanal-flow-choking model is established herein through the entropy relation, as it satisfies all the conservation-laws of nature. The physical insight of the boundary-layer-blockage persuaded nanoscale Sanal-flow-choking in diabatic flows presented in this article sheds light on finding solutions to numerous unresolved scientific problems in physical, chemical and biological sciences carried forward over the centuries because the mathematical-model describing the phenomenon of Sanal-flow-choking is a unique scientific-language of the real-world-fluid flows. The 3D-boundary-layer-blockage factors presented herein for various gases are universal-benchmark-data for performing high-fidelity in silico, in vitro and in vivo experiments in nanotubes.


2018 ◽  
Vol 378 (7) ◽  
pp. 595-597 ◽  
Author(s):  
Frederic S. Resnic ◽  
Michael E. Matheny
Keyword(s):  

1997 ◽  
Vol 13 (02) ◽  
pp. 93-100
Author(s):  
Scott McGhee ◽  
Sivrama Nalluri ◽  
Ron Reeve ◽  
Robert Rongo ◽  
Fritz Prinz ◽  
...  

The application of robots to variable tasks in unstructured environments presents a series of problems that must be solved in order to achieve viable results Common teaching-type robots cannot be applied in these cases as the programming time and labor investment far exceed the time and cost of direct manual production. Numerically controlled (NC) robots programmed off-line by modified NC methods have been applied with economic success to program robots directly from computer-aided design (CAD) data where tasks are sufficiently repetitive and the operating environment is sufficiently structured Similarly, off-line programming systems have been developed by various robot manufacturers to generate instructions from CAD data for their robots. Likewise, developers of 3D simulation software have devised methods to merge CAD data with physical models of robots and system hardware to produce robot path programs that approximate the tasks to be performed. Each of these systems is unable to provide a totally automated means to program robot tasks directly from CAD data due to inaccuracies in the real-world elements and/or the models, and due to a lack of knowledge about the processes. A new approach to automatic robot programming is needed that is capable of dealing with:inherent differences between the CAD models and the real-world parts;uncertainties regarding the precise location and accessibility of the parts relative to the robot:process knowledge required to adapt these differences and uncertainties; andprocess knowledge essential to optimizing robot activities. Such an automatic robot programming system is being developed to meet the dual-use defense and commercial ship construction needs of American shipyards under the Technology Reinvestment Project (TRP) for Shipbuilding Robotics. This system automates the programmer's task of identifying location of welds, assigning weld process parameters and adaptive welding strategies to each joint. A procedural diagram for this system is shown in Figure 1. The results and benefits of this approach are described herein. Fig. 1Procedure for automatic off-line robot task planning


2019 ◽  
Vol 39 (2) ◽  
pp. 137-151
Author(s):  
Anirban Basu ◽  
Min-Woong Sohn ◽  
Brian Bartle ◽  
Kwun Chuen Gary Chan ◽  
Jennifer M. Cooper ◽  
...  

2016 ◽  
Vol 14 (3) ◽  
pp. 45
Author(s):  
Ros Porter ◽  
Hannah Bartholomew

Mathematical modelling is unfamiliar to many young mathematicians and can be a source of anxiety for many. Although many first year mathematics undergraduates will have used mathematical models throughout GCSE and A Level most are unaware of this. Very few understand what a mathematical model is, fewer still the concept of building a model. In our experience students are reluctant to try and build their own models and fail to see the value of modelling skills in the real world. We invited 3 speakers to attend a first year modelling lecture to talk about the models they use in their jobs with the intention that this would help students see that modelling skills and analytical thought processes are valuable tools for a maths graduate. The speakers had different employment backgrounds being from banking, research (chemistry) and transport engineering. Each spoke for approximately 10 mins. giving an outline of their field. The lecture was followed by tutorials in which students were asked to reflect on what the speakers had said and how this related to their own learning. Two of the speakers also attended the tutorials and were able to have more informal conversations with the students.


2018 ◽  
Vol 1 (1) ◽  
pp. 42
Author(s):  
Media Rosha

Educational city Bukittinggi has some Senior High School (SMA) and they are potential.  Learning process is doing well but not optimal yet. Mathematics teacher find the difficulties in build, solve and interprete mathematical models based and real world problem. In other case, it is one of the mathematics learning objectives for SMA. This case gives the negative impact. If teacher knows the models of a problem, she/he will use in explaining the lessson, so that the students find the benefit  of that mathematical concept. One way to solve this problem is give a workshop to teacher to construct mathematical model based on the real world context. In workshop teacher are teached how to model it, oriented to mathematical modelling. The objective of this workshop to help SMA mathematical teacher to model the real world problem, so that the problem solved. Workshop do with several analysis, they are analysis of need, orientation and discussion. Result that teacher reach are they are motivated to study how to model mathematical problem and they understand how to model it.


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