scholarly journals Alkenylbenzenes in Foods: Aspects Impeding the Evaluation of Adverse Health Effects

Foods ◽  
2021 ◽  
Vol 10 (9) ◽  
pp. 2139
Author(s):  
Andreas Eisenreich ◽  
Mario E. Götz ◽  
Benjamin Sachse ◽  
Bernhard H. Monien ◽  
Kristin Herrmann ◽  
...  
Keyword(s):  
Human Health ◽  
Food Production ◽  
Current Knowledge ◽  
Plant Food ◽  
Plant Metabolites ◽  
Secondary Plant Metabolites ◽  
Adverse Health Effects ◽  
Naturally Occurring ◽  
Genotoxic Compounds ◽  
Herbs And Spices

Alkenylbenzenes are naturally occurring secondary plant metabolites, primarily present in different herbs and spices, such as basil or fennel seeds. Thus, alkenylbenzenes, such as safrole, methyleugenol, and estragole, can be found in different foods, whenever these herbs and spices (or extracts thereof) are used for food production. In particular, essential oils or other food products derived from the aforementioned herbs and spices, such as basil-containing pesto or plant food supplements, are often characterized by a high content of alkenylbenzenes. While safrole or methyleugenol are known to be genotoxic and carcinogenic, the toxicological relevance of other alkenylbenzenes (e.g., apiol) regarding human health remains widely unclear. In this review, we will briefly summarize and discuss the current knowledge and the uncertainties impeding a conclusive evaluation of adverse effects to human health possibly resulting from consumption of foods containing alkenylbenzenes, especially focusing on the genotoxic compounds, safrole, methyleugenol, and estragole.

Secondary Plant Metabolites: Sources of Principles for Use in Agriculture, Food Industry and for Human Health Safety

2021 ◽  
Author(s):  
Gabriel Mihaita Daraban ◽  
Raluca Maria Hlihor ◽  
Maria Apostol ◽  
Marinela Badeanu ◽  
Daniela Suteu
Keyword(s):  
Human Health ◽  
Food Industry ◽  
Plant Metabolites ◽  
Secondary Plant Metabolites ◽  
Health Safety ◽  
Secondary Plant

scholarly journals Ursolic and Oleanolic Acids: Plant Metabolites with Neuromodulatory Potential

2021 ◽  
Author(s):  
Evelina Gudoityte ◽  
Odeta Arandarcikaite ◽  
Ingrida Mazeikiene ◽  
Vidmantas Bendokas ◽  
Julius Liobikas
Keyword(s):  
Current Knowledge ◽  
Plant Defence ◽  
Model Systems ◽  
Animal Origin ◽  
Antioxidant Systems ◽  
Plant Metabolites ◽  
Secondary Plant Metabolites ◽  
Beneficial Effects

Ursolic and oleanolic acids are secondary plant metabolites that are known to be involved in the plant defence system against water loss and pathogens. Nowadays these triterpenoids are also regarded as potential pharmaceutical compounds and there is mounting experimental data that either purified compounds or triterpenoid-enriched plant extracts exert various beneficial effects, including anti-oxidative, anti-inflammatory and anticancer, on model systems of both human or animal origin. Some of those effects have been linked to the ability of ursolic and oleanolic acids to modulate intracellular antioxidant systems and also inflammation- and cell death-related pathways. Therefore, our aim was to review the current knowledge about the distribution of ursolic and oleanolic acids in plants, bioavailability and pharmacokinetic properties of these triterpenoids and their derivatives, and to discuss their neuromodulatory effects in vitro and in vivo.

UV-B-Induced Secondary Plant Metabolites - Potential Benefits for Plant and Human Health

2012 ◽  
Vol 31 (3) ◽  
pp. 229-240 ◽  
Author(s):  
M. Schreiner ◽  
I. Mewis ◽  
S. Huyskens-Keil ◽  
M. A. K. Jansen ◽  
R. Zrenner ◽  
...  
Keyword(s):  
Human Health ◽  
Plant Metabolites ◽  
Secondary Plant Metabolites ◽  
Potential Benefits ◽  
Secondary Plant

scholarly journals Advances in Biosynthesis and Biological Functions of Proanthocyanidins in Horticultural Plants

Foods ◽  
2020 ◽  
Vol 9 (12) ◽  
pp. 1774
Author(s):  
Dan Yu ◽  
Ting Huang ◽  
Bin Tian ◽  
Jicheng Zhan
Keyword(s):  
Nutritional Value ◽  
Biosynthetic Pathway ◽  
Molecular Mechanisms ◽  
Current Knowledge ◽  
Future Research ◽  
Plant Metabolites ◽  
Secondary Plant Metabolites ◽  
New Findings ◽  
Processed Products

Proanthocyanidins are colorless flavonoid polymers condensed from flavan-3-ol units. They are essential secondary plant metabolites that contribute to the nutritional value and sensory quality of many fruits and the related processed products. Mounting evidence has shown that the accumulation of proanthocyanidins is associated with the resistance of plants against a broad spectrum of abiotic and biotic stress conditions. The biosynthesis of proanthocyanidins has been examined extensively, allowing for identifying and characterizing the key regulators controlling the biosynthetic pathway in many plants. New findings revealed that these specific regulators were involved in the proanthocyanidins biosynthetic network in response to various environmental conditions. This paper reviews the current knowledge regarding the control of key regulators in the underlying proanthocyanidins biosynthetic and molecular mechanisms in response to environmental stress. Furthermore, it discusses the directions for future research on the metabolic engineering of proanthocyanidins production to improve food and fruit crop quality.

PEAS AND PRODUCTS OF ITS PROCESSING OF - NONCONVENTIONAL RAW MATERIAL RESOURCES

2020 ◽  
Author(s):  
D.Y. Bolgova ◽  
◽  
N.A. Tarasenko ◽  
Z.S. Mukhametova ◽  
◽  
...  
Keyword(s):  
Chemical Composition ◽  
Human Health ◽  
Food Production ◽  
Food Industry ◽  
Raw Material ◽  
Plant Proteins ◽  
Material Resources ◽  
The Rich

Nutrition is an important factor that affects human health. The use of plant proteins as various additives in food production has now been actively developed. The rich chemical composition of pea grains determines the possibility of application in the food industry. Peas are characterized by good assimilability and degree of digestion.

Food, Water and the Consequences of Society Not Valuing the Environment

2019 ◽  
pp. 858-878 ◽  
Author(s):  
Tony Allan
Keyword(s):  
Political Economy ◽  
Human Health ◽  
Food Production ◽  
Food System ◽  
Food Prices ◽  
The Political ◽  
Environmental Services ◽  
Accounting Systems ◽  
The Impact

The first purpose of this chapter is to highlight the impact of the food system on environmental and human health. The delivery of secure affordable food is a political imperative. Unfortunately, the food system that delivers it is environmentally blind. Food prices do not effectively reflect the value of food and often seriously mislead on the costs and impacts of food production. For example, actual food production takes place in a failed market—the value of environmental services such as water and the supporting ecosystems are not taken into account. The second purpose is to summarize and expose the political economy of the different ‘market’ modes of the food system. It is shown that there are weak players such as underrewarded and undervalued farmers who support society by producing food and stewarding our unvalued environment. The inadequacies of accounting systems are also critiqued.

scholarly journals Lactobacillus Reuteri DSM 17938 (Limosilactobacillus reuteri) in Diarrhea and Constipation: Two Sides of the Same Coin?

Medicina ◽  
2021 ◽  
Vol 57 (7) ◽  
pp. 643
Author(s):  
Angela Saviano ◽  
Mattia Brigida ◽  
Alessio Migneco ◽  
Gayani Gunawardena ◽  
Christian Zanza ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Emergency Department ◽  
Abdominal Pain ◽  
Human Health ◽  
Bowel Disease ◽  
Chronic Constipation ◽  
Lactobacillus Reuteri ◽  
Current Knowledge ◽  
Gastrointestinal Symptoms ◽  
Inflammatory Bowel

Background and Objectives: Lactobacillus reuteri DSM 17938 (L. reuteri) is a probiotic that can colonize different human body sites, including primarily the gastrointestinal tract, but also the urinary tract, the skin, and breast milk. Literature data showed that the administration of L. reuteri can be beneficial to human health. The aim of this review was to summarize current knowledge on the role of L. reuteri in the management of gastrointestinal symptoms, abdominal pain, diarrhea and constipation, both in adults and children, which are frequent reasons for admission to the emergency department (ED), in order to promote the best selection of probiotic type in the treatment of these uncomfortable and common symptoms. Materials and Methods: We searched articles on PubMed® from January 2011 to January 2021. Results: Numerous clinical studies suggested that L. reuteri may be helpful in modulating gut microbiota, eliminating infections, and attenuating the gastrointestinal symptoms of enteric colitis, antibiotic-associated diarrhea (also related to the treatment of Helicobacter pylori (HP) infection), irritable bowel syndrome, inflammatory bowel disease, and chronic constipation. In both children and in adults, L. reuteri shortens the duration of acute infectious diarrhea and improves abdominal pain in patients with colitis or inflammatory bowel disease. It can ameliorate dyspepsia and symptoms of gastritis in patients with HP infection. Moreover, it improves gut motility and chronic constipation. Conclusion: Currently, probiotics are widely used to prevent and treat numerous gastrointestinal disorders. In our opinion, L. reuteri meets all the requirements to be considered a safe, well-tolerated, and efficacious probiotic that is able to contribute to the beneficial effects on gut-human health, preventing and treating many gastrointestinal symptoms, and speeding up the recovery and discharge of patients accessing the emergency department.

General principle of primary and secondary plant metabolites: Biogenesis, metabolism, and extraction

2021 ◽  
pp. 3-23
Author(s):  
Charles Oluwaseun Adetunji ◽  
Santwana Palai ◽  
Chika Precious Ekwuabu ◽  
Chukwuebuka Egbuna ◽  
Juliana Bunmi Adetunji ◽  
...  
Keyword(s):  
General Principle ◽  
Plant Metabolites ◽  
Secondary Plant Metabolites ◽  
Secondary Plant

scholarly journals Liquid–liquid phase separation in human health and diseases

2021 ◽  
Vol 6 (1) ◽  
Author(s):  
Bin Wang ◽  
Lei Zhang ◽  
Tong Dai ◽  
Ziran Qin ◽  
Huasong Lu ◽  
...  
Keyword(s):  
Phase Separation ◽  
Liquid Phase ◽  
Human Health ◽  
Essential Role ◽  
Current Knowledge ◽  
Vital Role ◽  
Liquid Phase Separation ◽  
Eukaryotic Cells ◽  
Liquid Liquid Phase Separation

AbstractEmerging evidence suggests that liquid–liquid phase separation (LLPS) represents a vital and ubiquitous phenomenon underlying the formation of membraneless organelles in eukaryotic cells (also known as biomolecular condensates or droplets). Recent studies have revealed evidences that indicate that LLPS plays a vital role in human health and diseases. In this review, we describe our current understanding of LLPS and summarize its physiological functions. We further describe the role of LLPS in the development of human diseases. Additionally, we review the recently developed methods for studying LLPS. Although LLPS research is in its infancy—but is fast-growing—it is clear that LLPS plays an essential role in the development of pathophysiological conditions. This highlights the need for an overview of the recent advances in the field to translate our current knowledge regarding LLPS into therapeutic discoveries.

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