Abdominal Muscles and Metabolic Syndrome According to Patient Sex: A Retrospective Cross-Sectional Study

Computed tomography (CT) is a reference method for measuring skeletal muscle mass, and the amount of fat in the skeletal muscle can be calculated based on CT attenuation. This study aimed to comprehensively investigate the effect of muscle quality and quantity on metabolic syndrome (MetS) according to sex. This retrospective cross-sectional study enrolled 8081 individuals aged ≥20 years who underwent self-referral abdominopelvic CT at our hospital. The total abdominal muscle area (TAMA), low-attenuation abdominal muscle area (LAMA), normal-attenuation abdominal muscle area (NAMA), and extramyocellular lipid area (EMCLA) were measured using cross-sectional CT data of the L3 lumbar vertebrae. The TAMA and NAMA showed negative correlations with risk factors for MetS and a positive correlation with high-density lipoprotein cholesterol, whereas the LAMA and EMCLA showed an inverse trend in both the sexes (p < 0.001). After adjusting for various factors, a higher LAMA index and the ratio of LAMA to TAMA were associated with a higher prevalence of MetS. High TAMA indices were associated with a lower prevalence of MetS. Furthermore, muscle quality and quantity were associated with the prevalence of MetS in both males and females. However, the LAMA showed a stronger association with MetS in males than in females.

Download Full-text

Association Between Muscle Quality Measured by Abdominal Computed Tomography and Subclinical Coronary Atherosclerosis

Arteriosclerosis Thrombosis and Vascular Biology ◽

10.1161/atvbaha.120.315054 ◽

2020 ◽

Author(s):

Min Jung Lee ◽

Hong-Kyu Kim ◽

Eun Hee Kim ◽

Sung Jin Bae ◽

Kyung Won Kim ◽

...

Keyword(s):

Computed Tomography ◽

Skeletal Muscle ◽

Adipose Tissue ◽

Coronary Artery ◽

Coronary Artery Calcification ◽

Coronary Atherosclerosis ◽

Abdominal Muscle ◽

Muscle Quality ◽

Muscle Area ◽

Cross Sectional

Objective: Low muscle mass was known to be associated with cardiovascular diseases. However, only few studies investigated the association between muscle quality and subclinical coronary atherosclerosis. Thus, we evaluated whether muscle quality measured by abdominal computed tomography is associated with the risk of coronary artery calcification. Approach and Results: We conducted a cross-sectional study on 4068 subjects without cardiovascular disease who underwent abdominal and coronary computed tomography between 2012 and 2013 during health examinations. The cross-sectional area of the skeletal muscle was measured at the L3 level (total abdominal muscle area, total abdominal muscle area) and segmented into normal attenuation muscle area, low attenuation muscle area, and intramuscular adipose tissue. We calculated the normal attenuation muscle area/total abdominal muscle area index, of which a higher value reflected a higher proportion of good quality muscle (normal attenuation muscle area) and a lower proportion of myosteatosis (low attenuation muscle area and intramuscular adipose tissue). In women, as the normal attenuation muscle area/total abdominal muscle area quartiles increased, the odds ratios (95% CIs) for significant coronary artery calcification (>100) consistently decreased (0.44 [0.24–0.80], 0.39 [0.19–0.81], 0.34 [0.12–0.98]; P =0.003) after adjusting for cardiovascular risk factors including visceral fat area and insulin resistance. In men, the odds ratios in the Q2 group were significantly lower than those in the Q1, but the association was attenuated in Q3–4 after adjustment. Conclusions: A higher proportion of good quality muscle was strongly associated with a lower prevalence of significant coronary artery calcification after adjustment, especially in women. Poor skeletal muscle quality may be an important risk factor for subclinical coronary atherosclerosis.

Download Full-text

Association between metabolic syndrome and thyroid stimulating hormone - A cross sectional study

Medpusle International Journal of Medicine ◽

10.26611/1021922 ◽

2019 ◽

Vol 9 (2) ◽

pp. 87-90

Author(s):

Karanam Madhuri ◽

◽

Rishi Kumar Venkatachalam ◽

A Nasreen Begum ◽

Shamsheer Khan P ◽

...

Keyword(s):

Metabolic Syndrome ◽

Cross Sectional Study ◽

Thyroid Stimulating Hormone ◽

Sectional Study ◽

Cross Sectional ◽

Stimulating Hormone

Download Full-text

Impact of high visceral adiposity index associated with metabolic syndrome on erectile function in sexually active men: results of a cross‐sectional study

International Journal of Clinical Practice ◽

10.1111/ijcp.14111 ◽

2021 ◽

Author(s):

Mustafa Suat Bolat ◽

Mustafa Latif Ozbek ◽

Bekir Şahin ◽

Merve Yılmaz ◽

Fatih Kocamanoglu ◽

...

Keyword(s):

Metabolic Syndrome ◽

Erectile Function ◽

Cross Sectional Study ◽

Visceral Adiposity ◽

Visceral Adiposity Index ◽

Sexually Active ◽

Sectional Study ◽

Cross Sectional ◽

Adiposity Index

Download Full-text

The association between dietary antioxidant quality score with metabolic syndrome and its components in Iranian adults: A cross‐sectional study

Food Science & Nutrition ◽

10.1002/fsn3.2067 ◽

2020 ◽

Author(s):

Mahshid Shahavandi ◽

Hossein Shahinfar ◽

Nastaran payande ◽

Fatemeh Sheikhhossein ◽

Kurosh Djafarian ◽

...

Keyword(s):

Metabolic Syndrome ◽

Cross Sectional Study ◽

Quality Score ◽

Sectional Study ◽

Cross Sectional ◽

Dietary Antioxidant

Download Full-text

Association of Serum Bilirubin Level with Metabolic Syndrome and Non-Alcoholic Fatty Liver Disease: A Cross-Sectional Study of 1672 Obese Children

Journal of Clinical Medicine ◽

10.3390/jcm10132812 ◽

2021 ◽

Vol 10 (13) ◽

pp. 2812

Author(s):

Cristina Bellarosa ◽

Giorgio Bedogni ◽

Annalisa Bianco ◽

Sabrina Cicolini ◽

Diana Caroli ◽

...

Keyword(s):

Metabolic Syndrome ◽

Fatty Liver ◽

Fatty Liver Disease ◽

Serum Bilirubin ◽

Cross Sectional Study ◽

Sectional Study ◽

Obese Children ◽

Cross Sectional ◽

Alcoholic Fatty Liver ◽

Alcoholic Fatty Liver Disease

As in adults, obesity also plays a central role in the development of metabolic syndrome (MS) in children. Non-alcoholic fatty liver disease (NAFLD) is considered a manifestation of MS. Not only MS but also NAFLD seem to be inversely associated with serum bilirubin concentrations, an important endogenous tissue protector when only mild elevated. The aim of the study was to evaluate the association between serum bilirubin levels and the prevalence of MS and NAFLD in Italian obese children and adolescents. A retrospective cross-sectional study was performed in 1672 patients aged from 5 to 18 years. Clinical and laboratory parameters were assessed. NAFLD was measured by liver ultrasonography. The study was approved by the Ethical Committee of the Istituto Auxologico Italiano (research project code 1C021_2020, acronym BILOB). MS was present in 24% and fatty liver (FL) in 38% of this population. Bilirubin was not associated with FL and MS as a whole, but it was inversely associated only with selected components of MS, i.e., large WC, high blood pressure and high triglycerides. Our data suggest that bilirubin is not protective against MS and NAFLD in the presence of severe obesity.

Download Full-text