3D-Analysis of Mouth, Nose and Eye Parameters in Children with Fetal Alcohol Syndrome (FAS)

Background: Fetal alcohol spectrum disorder (FASD) is a developmental disorder with severe negative lifetime consequences for the affected person. Numerous diagnostic methods for facial assessment in FAS exist, but most of them are based on subjective evaluations. Our aim was therefore to find objective methods for the verification of FAS(D). Methods: 58 children (28 FAS; 30 controls) were examined prospectively. 3D facial scans were performed for each child and facial parameters at the mouth, nose and eye regions were measured and compared between the groups. Results: Significant differences could be found for the distance between right and left sulcus nasi at the transition point to the philtrum (p < 0.001), for the inner canthal distance (p = 0.001) as well as for the right and left palpebral fissure length (p < 0.001). No significant difference between the FAS and control children could be found for the measurements of mouth breadth (p = 0.267) and breadth between the left and right alares nasi (p = 0.260). Conclusions: Measurements of mouth breadth and nose breadth for the alares nasi are not suitable for FAS diagnosis. In contrast, digital contactless measurements of the distance between the right and left sulcus nasi at the transition point to the philtrum, as well as the inner canthal distance and palpebral fissure length of the left and right eyes, showed significant differences when comparing children with FAS to healthy controls. These measurements could thus be additional objective means for the verification of FAS.

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The Effect of Reflexology on Lactation in Women Who Had Cesarean Section: A Randomized Controlled Pilot Study

Complementary Medicine Research ◽

10.1159/000513924 ◽

2021 ◽

pp. 1-8

Author(s):

Sevde Aksu ◽

Pelin Palas Karaca

Keyword(s):

Pilot Study ◽

Cesarean Section ◽

Intervention Group ◽

Control Group ◽

Breast Pain ◽

Randomized Controlled ◽

Significant Difference ◽

The Right ◽

Documentation Tool ◽

And Control

Aim: The research was conducted as a randomized controlled pilot study to evaluate the effects of reflexology on lactation in mothers who delivered by cesarean section (CS). Methods: A single-blind randomized controlled experimental study was conducted with a total of 60 postpartum women in the reflexology application (n = 30) and control groups (n = 30). After the CS, the mothers in the control group were given approximately 3-h routine nursing care after recovering from the effects of anesthesia; the introductory information form was applied, and the Breastfeeding Charting System and Documentation Tool (LATCH) and visual analog scale (VAS) for the signs of the onset of lactation were implemented on the first and second days. Reflexology was applied to the women in the intervention group after an average of 3 h following the mother’s condition had become stable and she had recovered from the effects of anesthesia. Reflexology was applied a total of 20 min – 10 min for the right foot, 10 min for the left foot – twice a day with 8-h intervals on the first and second days after CS. After the last reflexology application, the LATCH and VAS for the signs of the onset of lactation were applied. Results: Of the women, 70% breastfed their babies within 60 min after delivery; 46.7% of the mothers received breastfeeding training and 81.7% needed support for breastfeeding after the CS. The LATCH breastfeeding scores of the women in the intervention group on both days were significantly higher compared to those of the women in the control group (p < 0.001). On the first day after the CS, apart from breast pain, there was no significant difference between the two groups in terms of breast heat and breast tension (p > 0.05). On the second day after the CS, apart from breast tension, there was no significant difference between the groups in terms of breast heat and breast pain (p < 0.05). In the study, women in the intervention group were found to have higher scores in terms of all three symptoms compared to the control group (p < 0.05). Conclusions: In the study, it was determined that LATCH scores and signs of the onset of breastfeeding increased in the mothers who received reflexology after CS.

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Somatosensory Evoked Potentials in Schizophrenia a Lateralisation Study

The British Journal of Psychiatry ◽

10.1192/bjp.157.6.881 ◽

1990 ◽

Vol 157 (6) ◽

pp. 881-887 ◽

Cited By ~ 4

Author(s):

Paul Furlong ◽

Paul Barczak ◽

Gwilym Hayes ◽

Graham Harding

Keyword(s):

Index Finger ◽

Objective Measure ◽

Control Group ◽

Temporal Region ◽

Control Groups ◽

Significant Difference ◽

Schizophrenic Patients ◽

Left And Right ◽

And Control ◽

Stimulation Of

The SSEPs obtained from 19 schizophrenics defined by RDC, DSM–III and PSE criteria Were compared with those from a control group of healthy volunteers. Previous findings of an abnormal lack of lateralising response in schizophrenic patients were not replicated. No significant difference in either amplitude or morphology between the traces obtained from the two groups were recorded. Ipsilateral and contralateral latencies for stimulation of the left and right index finger showed no significant difference in peak latency for any component between patient and control group. When mean peak-to-peak amplitudes were plotted the contralateral component was always greater in amplitude than the ipsilateral one. An objective measure of the degree of lateralisation, the percentage lateralisation quotient, showed no lateralisation differences between the patient and control groups. A case of myogenic contamination of ipsilateral components was observed calling into doubt findings where no temporal region monitoring has been performed.

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A radiological evaluation of alveolar bone regeneration between the left and right mandibles and maxillae of the Chacma baboon

Journal of the South African Veterinary Association ◽

10.4102/jsava.v87i1.1310 ◽

2016 ◽

Vol 87 (1) ◽

Cited By ~ 1

Author(s):

Marthinus J. Kotze ◽

Kurt-W. Bütow ◽

Steve A. Olorunju ◽

Harry F. Kotze

Keyword(s):

Healing Rate ◽

Alveolar Bone ◽

Sufficient Information ◽

Digital Radiology ◽

Grey Scale ◽

Lack Of Information ◽

Significant Difference ◽

Left And Right ◽

Maxilla And Mandible ◽

The Right

There is a lack of information in comparing the healing rate between the left and right sides of the maxilla and mandible. Osteogenesis of alveolar bone was evaluated with digital radiology by comparing differences in bone density (BD) at different time points within the left and right maxilla and mandible. Alveolar bone defects were created in five healthy Chacma baboons. Standardised x-ray images were acquired over time and the densities of the selected trauma areas were measured pre-operatively, post-operatively and at 3 and 6 weeks post-operatively. Differences in densities were statistically tested. There was no significant difference when the grey scale averages of the combined first and fourth quadrants (right side) and combined second and third quadrants (left side) were compared pre-operatively (t = 0.70), immediately post-operatively (t = 0.34), 3 weeks post-operatively (t = 0.40) and 6 weeks post-operatively (t = 0.66). There was also no significant difference between the values for the first and second quadrants (maxilla) pre-operatively (t = 0.37), immediately post-operatively (t = 0.30), 3 weeks post-operatively (t = 0.30) and 6 weeks post-operatively (t = 0.38); the third and fourth quadrants (mandible) were also not significantly different pre-operatively (t = 0.29), immediately post-operatively (t = 0.69), 3 weeks post-operatively (t = 0.07) and 6 weeks postoperatively (t = 0.06). However, the results showed an increased predisposition of the right side to regenerate faster than the left side and indicated sufficient information to investigate the effect of laterality and preferred side of mastication on the rate of healing and alveolar BD in the maxilla and mandible.

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The outcome of ablation for non-paroxysmal atrial fibrillation targeting spatiotemporal electrogram dispersion compared with ganglionated plexi ablation

European Heart Journal ◽

10.1093/ehjci/ehaa946.0617 ◽

2020 ◽

Vol 41 (Supplement_2) ◽

Author(s):

K Sakata ◽

T Tanaka ◽

S Yamashita ◽

K Yamashiro

Keyword(s):

Atrial Fibrillation ◽

Study Groups ◽

Atrial Arrhythmia ◽

Single Procedure ◽

Ganglionated Plexi ◽

Kaplan Meier ◽

Significant Difference ◽

Left And Right ◽

Fibrillatory Conduction ◽

And Control

Abstract Background Although catheter ablation targeting ganglionated plexi (GP) playing an important role in formation of triggers and substrates of atrial fibrillation (AF) has been reported as one of the effective ablation strategies in non-paroxysmal AF (non-PAF) patients, its effectiveness varies among the study groups. More recently, ablation targeting spatiotemporal electrogram dispersion (STED) areas, assumed to contain AF drivers in forms of rotational activation is proposed. However, the optimal ablation strategy for non-PAF is still controversial since the exact mechanisms of non-PAF are not well understood. Purpose To investigate the effectiveness of GP ablation for autonomic modification and STED ablation for modulation of AF drivers. Methods Consecutive 149 non-PAF patients who underwent STED ablation in our center were enrolled. We detected STED areas within the whole left and right atrium during AF using PentaRay®, and ablated them. If AF was terminated during STED ablation, we finished the procedure without burning the remaining STED areas. If not, electrical cardioversion was applied. The outcome was compared with that in consecutive 156 non-PAF patients undergoing GP ablation previously in our center. Results (1) The clinical characteristics were comparable between two groups (see Table). (2) A Kaplan-Meier curve showed that there was no significant difference between the freedom rates from non-PAF/non-paroxysmal atrial tachycardia (non-PAT) after single procedure in STED group and GP group (Figure, left). (3) However, the freedom rates from non-PAT in STED group was significantly lower than that GP group (Figure, right). Conclusions The recurrence type of atrial arrhythmia after ablation was remarkably different between ablation of STED and GP. STED ablation might eliminate fibrillatory conduction and control AF driver in patients with non-PAF. Freedom from atrial arrhythmia Funding Acknowledgement Type of funding source: None

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Behavior of Cellulose Biosynthetic Membrane as a Peritendinous Implant in Foals

Acta Scientiae Veterinariae ◽

10.22456/1679-9216.90825 ◽

2019 ◽

Vol 47 (1) ◽

Author(s):

Jackson Schade ◽

Maria Eduarda Gomes das Neves Oliveira ◽

Renato Silva de Souza ◽

Ivan Deconto ◽

William Timboni Teixeira ◽

...

Keyword(s):

Inflammatory Infiltrate ◽

Histopathological Examination ◽

Adhesion Formation ◽

Tendon Injuries ◽

Cellulose Membrane ◽

Superficial Digital Flexor Tendon ◽

Significant Difference ◽

The Right ◽

And Control ◽

Surgically Induced

Background: Tendon injuries are common in horses and are commonly associated with lameness and athletic career disruption. Adhesions formed between the tendons and the surrounding tissues compromise the sliding and movement of the structures, compromising their functionality. Therefore, the control of adhesion formation is critical to restore the structural integrity of the tendon, as well as its biomechanical function. The aim of this study was to evaluate the behavior of the biosynthetic cellulose membrane implanted in foals with surgically induced tendinitis of the superficial digital flexor.Materials, Methods & Results: Six healthy foals were used, which underwent tendinitis induction in the superficial digital flexor of the right and left forelimbs. The lesions was induced by local ischemia by crushing the tendon with hemostatic forceps. The biosynthetic cellulose membranewas implanted only in the right forelimb, involving the superficial digital flexor tendon in the region of the ischemia and the left forelimb was used as control. After surgery, both forelimb were immobilized with synthetic plaster cast for 15 days. Ultrasonography was performed in six foals immediately before (M0), at 15° (M1) at and 30° (M2) day, and three were evaluate at 45° (M3) and 60° (M4) day after surgery. Incisional biopsies were performed in three animals on the 30° day and in three animals on the 60° day after surgery. Histopathological examination involved the analysis of tissue disorganization, presence and type of inflammatory infiltrate and neovascularization, according to the score of 0 to 3. Ultrasonography allowed visualization of the membrane, which was characterized as a continuous hyperechoic line at the edges of the tendon at 15 days (M1). In addition, at 30 and 45 days after surgery, interruption of the hyperechoic line and reduction of echogenicity were observed, and no echogenic lines were observed at 60 days after surgery. During the biopsies, the fragments obtained from the treated limb were presented with easily detachable layers and separate layers of tissue during histological cutting and the slides preparations. There was no significant difference in relation to the histopathological scores between the treated and control member. The inflammatory infiltrate was predominantly of mononuclear cells and fibroblasts, with identification of giant cell in a foal at 30 days. Neovascularization was observed in all limbs, treated and controls at 30 days and in two treated limbs and three control at 60 days. It was possible to identify the synthetic cellulose membrane by histopathology in only two limbs treated at 30 days and in no limb at 60 days.Discussion: The degree of tendonitis induced in the present study was considered mild according to ultrasonographic analysis at 15 days after surgery. This fact limited the evaluation of the biosynthetic cellulose membrane in the prevention of adhesions, since they were not observed in both groups. However, the ability of the membrane to minimize adhesion formation can be suggest by the macroscopically observed individualization of the tissue layers during histological sections and slides preparation. Ultrasonographic analysis allowed the visualization of the membrane, as well as its positioning and the absorption process. Therefore, ultrasonography can be used in post-implantation monitoring of the membrane. The comparison of the histopathological scores demonstrates the biocompatibility of the biosynthetic cellulose membrane when implanted in foals submitted to surgically induced tendinitis, since there was no difference when compared to treated and control limbs. Therefore, it can be used safely in the treatment of tendon injuries in horses.

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A Study on the Optimization of High School Buildings for Evacuation Safety: Classroom Layout and Ramps in Korea

Turkish Journal of Computer and Mathematics Education (TURCOMAT) ◽

10.17762/turcomat.v12i5.961 ◽

2021 ◽

Vol 12 (5) ◽

pp. 358-368

Author(s):

Chang-Jun Choi, Ha-Sung Kong

Keyword(s):

High School ◽

Grade Level ◽

School Buildings ◽

Layout Analysis ◽

The Third ◽

School Year ◽

Significant Difference ◽

Left And Right ◽

Evacuation Safety ◽

The Right

This study used the Pathfinder program to evaluate evacuation safety by assuming evacuation training in high school buildings and changing classroom layout. Analysis of the final evacuation requirements for Scenario 2, which currently has a concentration of classrooms on the third floor of the building, showed that Scenario 2 reduced 29.6 seconds to 173.9 seconds compared to Scenario 1's 203.5 seconds. However, the analysis of Scenario 3, in which 10 classrooms and personnel of three grades were placed equally on the left and right sides of the building, showed that the final evacuation requirements were reduced 3.9 seconds to 170.0 seconds compared to Scenario 2, but there was no significant difference. Scenario 3, which has more the efficiency of school year operation by placing classroom layout on the same floor by grade level than Scenario 2, in which more classrooms and students were placed downstairs. In each scenario, an analysis of the final evacuation requirements showed that the evacuation exit T1 on the left side of the building was 28 seconds or more shorter than T3 on the right side of the building. Therefore, it was analyzed that proper classroom layout and ramp facilities in high school buildings ensure evacuation safety

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Changes in the Stiffness of Thigh Muscles in the Left and Right Limbs During Six Weeks of Plyometric Training in Volleyball Players

Polish Journal of Sport and Tourism ◽

10.2478/pjst-2018-0010 ◽

2018 ◽

Vol 25 (2) ◽

pp. 20-24 ◽

Cited By ~ 2

Author(s):

Dariusz Mroczek ◽

Edward Superlak ◽

Marek Konefał ◽

Krzysztof Maćkała ◽

Paweł Chmura ◽

...

Keyword(s):

Good Method ◽

Optimal Level ◽

Muscle Stiffness ◽

Plyometric Training ◽

Thigh Muscles ◽

Left Limb ◽

Significant Difference ◽

Volleyball Players ◽

Left And Right ◽

The Right

Abstract Introduction. Monitoring muscle stiffness in athletes can be a good method of assessing fatigue caused by high training loads, and the early detection of fatigue can help prevent the occurrence of micro-trauma in the muscles that can cause contusions. The research carried out by Wilson et al. [1] confirmed that an optimal level of muscle stiffness is significantly correlated with high muscle loads. The aim of the current study was to determine changes in muscle stiffness of the left and right thighs during six weeks of plyometric training (PT) in volleyball players. Material and methods. The study involved 16 volleyball players from the second-league Opole University of Technology Club (age = 21.12 ± 1.66 years, height = 191.62 ± 5.73 cm, and weight = 86.25 ± 6.66 kg) with at least five years of competitive experience (7.5 ± 2.44 years). Muscle stiffness was measured during three stages of the plyometric training using a MYOTON PRO device (Estonia). Results. An RM-ANOVA analysis showed a significant difference in the resting stiffness of the semitendinosus (posterior thigh) muscles of the left and right limbs before the plyometric training began, but no significant differences were found in the stiffness of these muscles in the fourth or sixth weeks of training. The results of the measurement performed for the anterior muscles of the thigh did not reveal a significant difference in the stiffness of the left limb compared to that of the right limb in subsequent weeks of training. Conclusion. The loads used in plyometric training in volleyball players caused a decrease in the differences in muscle stiffness between the left and right limbs, and in both limbs, adaptation trended towards an increase or a decrease in stiffness.

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Pulmonary clearance of 99mTc-DTPA: influence of background activity

Journal of Applied Physiology ◽

10.1152/jappl.1988.64.3.1045 ◽

1988 ◽

Vol 64 (3) ◽

pp. 1045-1049 ◽

Cited By ~ 17

Author(s):

M. P. Barrowcliffe ◽

C. Otto ◽

J. G. Jones

Keyword(s):

Background Activity ◽

Left Lung ◽

Scintillation Detectors ◽

Half Time ◽

Left Chest ◽

Tissue Accumulation ◽

Pulmonary Clearance ◽

Significant Difference ◽

Left And Right ◽

The Right

We examined the effect of intravascular and tissue accumulation of tracer when measuring pulmonary clearance of sodium pertechnetate-labeled diethylenetriamine pentaacetate (99mTc-DTPA). Pigs were intubated with endobronchial tubes, permitting deposition of an aerosol of 99mTc-DTPA only into the left lung. Scintillation detectors recorded radioactivity separately from one thigh and from the lung and chest wall on the left and right side. 99mTc-DTPA was given intravenously after 30 min, so that the chest counts from the left lung could be corrected for background activity in either the right lung or the thigh. The uncorrected clearance half time (t1/2) mean± SE from the left chest was 118.5 ± 14.4 min. When corrected for background activity in the right chest, the t1/2 was 82.1 ± 10.5 min, and when corrected for background activity in the thigh, the t1/2 was 80.9 ± 10.6 min. There was no significant difference between t1/2 corrected by the measurements from the right chest or the thigh, and in four of five animals the corrected t1/2 by either method was significantly different from the uncorrected t1/2 (P less than 0.05). There was no correlation between the uncorrected t1/2 and the magnitude of the required correction. We conclude that correction for intravascular and tissue accumulation of tracer is an important refinement of the technique and can easily be accomplished by measuring accumulation of tracer in the thigh.

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Lateral comparisons using Fishman's skeletal maturation assessment

The Angle Orthodontist ◽

10.2319/043014-312.1 ◽

2014 ◽

Vol 85 (3) ◽

pp. 408-412 ◽

Cited By ~ 2

Author(s):

Abraham N. Safer ◽

Peter Homel ◽

David D. Chung

Keyword(s):

Bone Development ◽

Surgical Patients ◽

Skeletal Maturation ◽

Age And Gender ◽

Left Hand ◽

Right Hand ◽

Significant Difference ◽

Left And Right ◽

And Gender ◽

The Right

ABSTRACT Objective: To assess lateral differences between ossification events and stages of bone development in the hands and wrists utilizing Fishman's skeletal maturation indicators (SMIs). Materials and Methods: The skeletal ages of 125 subjects, aged 8 to 20 years, were determined with left and right hand-wrist radiographs using Fishman's SMI assessment. Each subject was also given the Edinburgh Handedness Questionnaire to assess handedness. The skeletal ages of both hand-wrist radiographs were analyzed against each other, handedness, chronologic age, and gender. Results: There were no significant differences overall in right and left SMI scores (P = .70); 79% of all patients showed no difference in right and left SMI scores, regardless of handedness, gender, or age. However, when patients were categorized based on clinical levels of SMI score for the right hand-wrist, there was a significant difference (P = .01) between the SMI 1-3 group and the SMI 11 group. Subjects in the SMI 1-3 group were more likely to show a left > right SMI score, while subjects in the SMI 11 group were likely to show a right > left SMI score. Conclusion: Although no significant overall lateral differences in SMI scores were noted, it may be advisable to obtain a left hand-wrist radiograph and/or additional diagnostic information to estimate completion of growth in young surgical patients.

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Growth-Related Differences in Maximum Laterotrusion and Retrusion between Children and Adults

The Angle Orthodontist ◽

10.2319/011508-21.1 ◽

2009 ◽

Vol 79 (2) ◽

pp. 265-270 ◽

Cited By ~ 6

Author(s):

Claudia A. Reicheneder ◽

Peter Proff ◽

Uwe Baumert ◽

Tomas Gedrange

Keyword(s):

Temporomandibular Joint ◽

Null Hypothesis ◽

Population Based ◽

Adult Group ◽

Population Based Study ◽

Significant Difference ◽

Left And Right ◽

The Mean ◽

The Right

Abstract Objective: To test the null hypothesis that there are no differences between children and adults in maximum laterotrusion and maximum retrusion on the right and left sides. Materials and Methods: This population-based study included 81 randomly selected children between the ages of 6 and 10 years and 67 adults. Kinematic variables were measured with the ultrasonic JMA-System for registration. Results: The mean maximum laterotrusion of the children's group (10.6 ± 1.5 mm on the left, 11.0 ± 1.7 mm on the right) was significantly smaller than that of the adult group (11.7 ± 2.0 mm on the left, 12.2 ± 1.7 mm on the right). The maximum laterotrusion of the children's group corresponded to about 90% on the left and right sides of that of the adult group. The mean maximum retrusion of the children's group was significantly bigger than that of the adult group. There, the adult values corresponded to 66.7% on the left and 50% on the right side of the children's values. No significant difference in maximum laterotrusion and retrusion was noted on the right and left sides, and no significant differences according to gender specificities were observed in either group. Conclusions: The hypothesis is rejected. In development of the temporomandibular joint, maximum laterotrusion on the right and left sides increases significantly with age, and maximum retrusion decreases significantly with age.

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