scholarly journals Quality of Life of Cancer Patients Treated with Chemotherapy

2020 ◽  
Vol 17 (19) ◽  
pp. 6938
Author(s):  
Anna Lewandowska ◽  
Grzegorz Rudzki ◽  
Tomasz Lewandowski ◽  
Michał Próchnicki ◽  
Sławomir Rudzki ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Karnofsky Performance Status ◽  
Performance Status ◽  
Life Quality ◽  
Disease Process ◽  
Well Being ◽  
Life Questionnaire ◽  
Cross Sectional

Background: Life-quality tests are the basis for assessing the condition of oncological patients. They allow for obtaining valuable information from the patients regarding not only the symptoms of disease and adverse effects of the treatment but also assessment of the psychological, social and spiritual aspects. Taking into account assessment of the quality of life made by the patient in the course of disease has a positive effect on the well-being of patients, their families and their caregivers as well as on satisfaction with the interdisciplinary and holistic oncological care. Methods: A population-based, multi-area cross-sectional study was conducted among patients with cancer in the study in order to assess their life quality. The method used in the study was a clinical interview. Quality of life was measured using the EQ-5D-5L Quality of Life Questionnaire, the Karnofsky Performance Status, our own symptom checklist, Edmonton Symptom Assessment and Visual Analogue Scale. Results: In the subjective assessment of fitness, after using the Karnofsky fitness index, it was shown that 28% (95% CI (confidence interval): 27–30) of patients declared the ability to perform normal physical activity. In the assessment the profile, quality of life and psychometric properties of EQ-5D-5L, it was shown that patients had the most severe problems in terms of self-care (81%, 95% CI: 76–89) and feeling anxious and depressed (63%, 95% CI: 60–68). Conclusions: Cancer undoubtedly has a negative impact on the quality of life of patients, which is related to the disease process itself, the treatment used and the duration of the disease.

scholarly journals Psychological and spiritual well-being aspects of the quality of life in colostomy patients

2018 ◽  
Vol 75 (6) ◽  
pp. 611-617
Author(s):  
Gordana Repic ◽  
Suncica Ivanovic ◽  
Cedomirka Stanojevic ◽  
Sanja Trgovcevic
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Age Groups ◽  
Well Being ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Psychological Well Being ◽  
Spiritual Well Being ◽  
The Mean

Background/Aim. Colorectal cancer and its treatment can have a negative impact on the quality of life which has become an important outcome measure for cancer patients. The aim of this work was assessment of psychological and spiritual dimension of the quality of life in colostomy patients, regarding the gender and age. Methods. This is a cross-sectional study conducted at the Abdominal Surgery Polyclinic in the Clinical Canter of Vojvodina among colostomy patients operated between January 2010 and June 2011. The instrument used in this study was Quality of Life Questionnaire for a Patient with an Ostomy (QOL-O). Results. Majority of respondents were male (M:F = 50.7% : 49.3%). The age ranged between 36?86 years. Respondents did not report difficulties in adjustment to stoma, but their great difficulty was to look at it and the sense of depression and anxiety. The care of stoma was worse perceived by younger respondents (p = 0.014). Respondents were mostly satisfied with their memorizing ability and having the sense of control. The lowest score was found in sensing satisfaction or enjoyment in life. The age had a significant impact on positive aspects of psychological well-being (p < 0.05). Higher scores were found among younger age groups. The mean score of spiritual well-being (6.47 ? 3.01) was lower than the mean score of psychological well-being (7.76 ? 2.35). There were no statistically significant differences regarding gender (t = -0.738, df = 65, p = 0.463) or age (F = 1.307, p = 0.280). Conclusion. Psychological and spiritual well-being in colostomy patients appeared to be at satisfactory level, but it is necessary to provide tailor made support in order to prevent and resolve negative responses to stoma.

Assessment of Quality of Life in Outpatients With Advanced Cancer: The Accuracy of Clinician Estimations and the Relevance of Spiritual Well-Being—A Hoosier Oncology Group Study

2003 ◽  
Vol 21 (14) ◽  
pp. 2754-2759 ◽  
Author(s):  
Michael J. Fisch ◽  
Michael L. Titzer ◽  
Jean L. Kristeller ◽  
Jianzhao Shen ◽  
Patrick J. Loehrer ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Advanced Cancer ◽  
Performance Status ◽  
Well Being ◽  
Categorical Variables ◽  
Therapeutic Trial ◽  
Slight Variation ◽  
Cross Sectional ◽  
Spiritual Well Being

Purpose: To evaluate the association between quality-of-life (QOL) impairment as reported by patients and QOL impairment as judged by nurses or physicians, with and without consideration of spiritual well-being (SWB). Patients and Methods: A total of 163 patients with advanced cancer were enrolled onto a therapeutic trial, and cross-sectional data were derived from clinical and demographic questionnaires obtained at baseline, including assessment of patient QOL and SWB. Clinicians rated the QOL impairment of their patients as mild, moderate, or severe. Clinician-estimated QOL impairment and patient-derived QOL categories were compared. Correlation coefficients were estimated to associate QOL scores using different instruments. The analysis of variance method was used to compare Functional Assessment of Cancer Therapy–General scores on categorical variables. Results: There was no significant association between self-assessment scores and marital status, education level, performance status, or predicted life expectancy. However, a strong relationship between SWB and QOL was noted (P < .0001). Clinician-estimated QOL impairment matched the level of patient-derived QOL correctly in approximately 60% of cases, with only slight variation depending on the method of categorizing patient-derived QOL scores. The accuracy of clinician estimates was not associated with the level of SWB. Interestingly, a subset analysis of the inaccurate estimates revealed an association between lower SWB and clinician underestimation of QOL impairment (P = .0025). Conclusion: Clinician estimates of QOL impairment were accurate in more than 60% of patients. SWB is strongly associated with QOL, but it is not associated with the overall accuracy of clinicians’ judgments about QOL impairment.

scholarly journals Influence of Sleep Disturbances on Quality of Life of Iranian Menopausal Women

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Zohreh Yazdi ◽  
Khosro Sadeghniiat-Haghighi ◽  
Amir Ziaee ◽  
Khadijeh Elmizadeh ◽  
Masomeh Ziaeeha
Keyword(s):  
Quality Of Life ◽  
Daytime Sleepiness ◽  
Sleep Disturbances ◽  
Negative Impact ◽  
Berlin Questionnaire ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Obstructive Sleep ◽  
Menopausal Women

Background. Subjective sleep disturbances increase during menopause. Some problems commonly encountered during menopause, such as hot flushes and sweating at night, can cause women to have difficulty in sleeping. These complaints can influence quality of life of menopausal women.Methods. This cross-sectional study was performed on menopausal women attending health centers in Qazvin for periodic assessments. We measured excessive daytime sleepiness by Epworth sleepiness scale (ESS), obstructive sleep apnea (OSA) by the Berlin questionnaire, and insomnia by the insomnia severity index (ISI). We evaluate quality of life by the Menopause specific quality of life questionnaire (MENQOL).Results. A total of 380 menopausal women entered the study. Mean age of participated women was 57.6 ± 6.02. Mean duration of menopause was 6.3 ± 4.6. The frequency of severe and moderate insomnia was 8.4% (32) and 11.8% (45). Severe daytime sleepiness (ESS ≥ 10) was present in 27.9% (80) of the participants. Multivariate analytic results show that insomnia and daytime sleepiness have independent negative impact on each domain and total score of MENQOL questionnaire.Conclusion. According to our findings, EDS and insomnia are frequent in menopausal women. Both EDS and insomnia have significant quality of life impairment.

scholarly journals Quality of Life (QOL) in Patients with Acromegaly Is Severely Impaired: Use of a Novel Measure of QOL: Acromegaly Quality of Life Questionnaire

2005 ◽  
Vol 90 (6) ◽  
pp. 3337-3341 ◽  
Author(s):  
Susannah V. Rowles ◽  
L. Prieto ◽  
X. Badia ◽  
Steven M. Shalet ◽  
Susan M. Webb ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Signs And Symptoms ◽  
Well Being ◽  
Cross Sectional Study ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Quality Of Life Questionnaire ◽  
Utility Index ◽  
Igf I

Acromegaly Quality of Life Questionnaire (AcroQoL) is a new disease-generated quality of life (QOL) questionnaire comprising 22 questions covering physical and psychological aspects of acromegaly and subdivided into “appearance” and “personal relations” categories. We have performed a cross-sectional study of QOL in 80 patients [43 male (mean age, 54.2 yr; range, 20–84); median GH, 0.93ng/ml (range, &lt;0.3 to 23.7); IGF-I, 333.1 ng/ml (range, 47.7–899)] with acromegaly. In addition to AcroQoL, patients completed three generic QOL questionnaires: Psychological General Well-Being Schedule (PGWBS), EuroQol, and a signs and symptoms score (SSS). All three generic questionnaires confirmed impairment in QOL [mean scores: PGWBS, 69.6; EuroQol, visual analog scale, 66.4 (range, 20–100) and utility index, 0.7 (range, −0.07 to 0.92); and SSS, 12 (range, 0–27)]. There was no correlation between biochemical control and any measure of QOL. AcroQoL (57.3%; range, 18.2–93.2) correlated with PGWBS (r = 0.73; P &lt; 0.0001); and in patients with active disease, AcroQoL-physical dimension correlated with SSS (r = −0.67; P &lt; 0.0003). In all questionnaires, prior radiotherapy was associated with impaired QOL. In conclusion, these data underline the marked impact that acromegaly has on patients’ QOL and provide the first evidence validating AcroQoL against well-authenticated measures of QOL. This indicates the potential of AcroQoL as a patient-friendly measure of disease activity.

scholarly journals Perception of parents and caregivers regarding the impact of malocclusion on adolescents’ quality of life: a cross-sectional study

2016 ◽  
Vol 21 (6) ◽  
pp. 74-81 ◽  
Author(s):  
Lucas Guimarães Abreu ◽  
Camilo Aquino Melgaço ◽  
Mauro Henrique Abreu ◽  
Elizabeth Maria Bastos Lages ◽  
Saul Martins Paiva
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Functional Limitations ◽  
Well Being ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
The Impact ◽  
Parents And Caregivers

ABSTRACT Objective: The objective of this article was to assess the perception of parents and caregivers regarding the impact of malocclusion on adolescents’ oral health -related quality of life (OHRQoL). Methods: This cross-sectional study consisted of a sample of 280 parents/caregivers of 11 and 12-year-old adolescents who answered the Parental-Caregiver Perceptions Questionnaire (P-CPQ). Parent-assessed quality of life of adolescents was the dependent variable. The main independent variable was adolescents’ malocclusion which was diagnosed by means of the Dental Aesthetic Index (DAI). Based on DAI cut-off points, adolescents were classified into four grades of malocclusion, with different orthodontic treatment recommendations assigned to each grade: no need/slight treatment need, elective treatment, highly desirable treatment and mandatory treatment. Adolescents’ age and sex, as well as family monthly income, were considered as confounding variables. Statistical analysis involved descriptive statistics, bivariate analyses, and Poisson regression with robust variance. Results: Of the 280 parents/caregivers initially accepted in this study, 18 refused to answer the P-CPQ. Therefore, 262 individuals participated in this assessment, providing a response rate of 93.5%. The severity of adolescents’ malocclusion was significantly associated with a higher negative impact on parents’/caregivers’ perception on the oral symptoms (p< 0.05), functional limitations (p < 0.001), emotional well-being (p < 0.001), and social well-being (p < 0.001) subscale scores as well as on the overall P-CPQ score (p < 0.001), even after having been adjusted for the controlling variables. Conclusions: Parents/caregivers reported a negative impact of malocclusion on adolescents’ OHRQoL. Increased severity of malocclusion is associated with higher adverse impact on OHRQoL.

scholarly journals Análisis de la situación de salud en Cerro Guayabal

2017 ◽  
Vol 1 (1) ◽  
pp. 29
Author(s):  
Yira Annabell Vásquez Giler ◽  
Alina González Hernández ◽  
Paula Salomé Macías Moreira ◽  
Olimpia Victoria Carrillo Farnés
Keyword(s):  
Quality Of Life ◽  
Teaching Practice ◽  
Life Quality ◽  
Disease Process ◽  
Health State ◽  
Cross Sectional ◽  
Calidad De Vida ◽  
Critical Issues ◽  
Quality Health

El Análisis de Situación de Salud es una herramienta que busca mejorar la salud y calidad de vida de poblaciones. Se diseñó una investigación transversal, descriptiva; con doble propósito: relacio- nar condiciones de vida y comportamiento del proceso salud y enfermedad en la comunidad Cerro de Guayabal y realizar ejercicio práctico-docente con estudiantes del quinto semestre de Medicina. Se encuestaron 266 familias, 1134 personas (91%) de la población total. El 71% solo alcanza nivel de formación primaria. Más de la mitad tiene viviendas en condiciones regulares y cultura sanita- ria entre regular y mal. El 87% no tiene necesidades básicas cubiertas. Más del 50% son familias disfuncionales. El 56% se dispensarizó de riesgo y 11% enfermos. Dada las condiciones de vida y ausencia de centro de salud parece existir morbilidad oculta. Existe riesgo de accidentes de tránsito y laboral. Resultó un tema crítico la recolección de residuos, el acceso a agua potable y la conta- minación ambiental. Existe imperiosa necesidad de intervenciones de salud para mejorar el estado de salud y calidad de vida de esta comunidad. Palabras clave: calidad de vida, estado de salud, salud pública. Abstract: The Health Situation Analysis is a tool that seeks to improve the health and quality of life of pop- ulations. A cross-sectional descriptive study was designed; with dual purpose: to relate living con- ditions and health behavior and disease process in the Cerro de Guayabal community and make practical-teaching practice with students of the fifth semester of Medicine. 266 families, 1134 people (91%) of the total population were surveyed. Only 71% reached primary level. More than half are in regular housing conditions and health culture fair to poor. 87% do not cover basic needs. More than 50% are dysfunctional families. 56% were risk dispensary and 11% were sick. Given the living conditions and lack of health center it seems to be hidden morbidity. There is a risk of traffic and labor accidents. Waste collection, access to drinking water and environmental pollution were critical issues. There is an urgent need for health interventions to improve the health state and quality of life of this community. Key words: life quality, health state, public health.

Correlation Between Spiritual Well-being and Quality of Life in Patients With Urinary Incontinence: A Cross-sectional Descriptive Study

2020 ◽  
Vol 66 (12) ◽  
pp. 23-28
Author(s):  
Emel Gülnar ◽  
Hüsna Özveren ◽  
Ercan Yuvanç
Keyword(s):  
Quality Of Life ◽  
Urinary Incontinence ◽  
Well Being ◽  
Descriptive Study ◽  
University Hospital ◽  
Life Questionnaire ◽  
Cross Sectional ◽  
Chronic Illness Therapy ◽  
Spiritual Well Being

Urinary incontinence (UI) increases the risk of medical complications and psychosocial, physical, and emotional problems. PURPOSE: This cross-sectional descriptive study investigated the correlation between spiritual well-being (SWB) and quality of life (QOL) in patients with UI. METHODS: Patients with UI visiting an outpatient urology clinic of a university hospital in Turkey were invited to participate. Data were collected using the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being 12 Item Scale (FACIT-Sp-12) (range 0–48 with higher scores indicating better SWB) and the Incontinence Quality of Life Questionnaire (I-QOL) (range 0–100 with higher scores indicating better QOL). RESULTS: The sample consisted of 383 patients. Most were female (235; 61%), had completed high school (169; 44%), had experienced UI for an average of 3.54 years (SD 3.44), and were between 21 and 92 years of age (mean 52.7; SD 14). The mean I-QOL score was 65.31 ± 19.71 with subscores ranging from a low of 59.69 for social embarrassment to a high of 71.44 for psychosocial impact. The average FACIT-Sp-12 score was 28.00 ± 6.08. Overall I-QOL and FACIT-Sp-12 scores were weakly positively correlated (r = .235). CONCLUSION: In this study both QOL and SWB scores were good; higher UI-specific QOL scores and some subscores were associated with higher SWB scores and subscores. Incontinence QOL should be determined together with SWB in patients with UI.

scholarly journals The Relationship Between Periodontal Disease and Public Health: A Population-Based Study

2015 ◽  
Vol 8 (7) ◽  
pp. 110 ◽  
Author(s):  
Somaye Ansari Moghadam ◽  
Zohre Abdollahi ◽  
Sirous Risbaf Fakour ◽  
Alireza Ansari Moghaddam ◽  
Farin Kiany ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Periodontal Diseases ◽  
Smoking Habit ◽  
Life Quality ◽  
Well Being ◽  
Population Based ◽  
The Body ◽  
Life Questionnaire ◽  
The Relationship

<p><strong>BACKGROUND:</strong> Periodontal diseases, such as periodontitis, are considered the main cause of tooth loss in the elderly.The present study is aimed to determine the relationship between periodontal condition and quality of life. Quality of life consists of a range of people’s objective needs related to the self-perception of well-being.</p><p><strong>METHODS:</strong> This study was done from January 2014 to June 2015 in a healthcare clinic in Zahedan, southeast Iran. Using the random sampling method, the researchers enrolled 700 individuals over 35 years of age. The participants initially completed a demographic questionnaire consisting of data, such as age, sex, educational level, and smoking habit. Then, the periodontal chart was completed. Moreover, patients, based on the number of their natural teeth, were divided into two groups (≥10 teeth in both maxillary and mandible arches and &lt;10 teeth in at least one arch). The body mass index (BMI) was also measured.To assess the participants’ general health, the WHO’s quality of life questionnaire (WHOQOL-BREF) was used.</p><p><strong>RESULTS: </strong>Of the 700 enrolled individuals, 53.3% were womenand 47.7% were men. Moreover, most of the participants (63.71%) had BMI of less than 25 and 68% did not smoke.We found that as the people’s periodontal status deteriorated, their quality of life also declined and the total mean score in all four health domains decreased (P&lt;0.001)<strong>.</strong>Moreover, people with more than 10 teeth in both arches scored higher with respect to life quality than those with less than 10 teeth in at least one arch (P&lt;0.001).</p><p><strong>CONCLUSION: </strong>This studyindicates a decrease in the general quality of life in patients with periodontal disease.The authors suggest performing studies with larger sample sizes andcohort studies for more reliable results.</p>

scholarly journals Quality of life in women with endometriosis: a cross-sectional survey

2020 ◽  
Vol 29 (10) ◽  
pp. 2669-2677
Author(s):  
Agnieszka Bień ◽  
Ewa Rzońca ◽  
Marta Zarajczyk ◽  
Katarzyna Wilkosz ◽  
Artur Wdowiak ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Negative Impact ◽  
Perceived Health ◽  
Pain Scale ◽  
Moderate Intensity ◽  
Life Questionnaire ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Acceptance Of Illness

Abstract Purpose The aim of the study was to assess QoL and identify and analyse its determinants in women with endometriosis. Methods The study was performed in 2019 in health centres in Lublin (Poland) on 309 women with diagnosed endometriosis. In order to verify which factors affect QoL of the study participants, regression for qualitative variables (CATREG) was used. The applied research instruments included the WHOQOL-BREF quality of life questionnaire, the Acceptance of Illness Scale (AIS), the Laitinen Pain Scale, and a general questionnaire. Results The overall QoL score of the respondents was 3.30, whereas their overall perceived health score was 2.37. The highest QoL scores were found for the psychological domain 13.33, whereas the lowest QoL were found for the physical domain 11.52. Women with endometriosis have a moderate level of illness acceptance (24.64) and experience daily pain of moderate intensity (5.83). Conclusion Women with endometriosis rate their overall QoL higher than their overall perceived health. Perceived QoL in women with endometriosis is most commonly associated with their acceptance of illness, BMI, negative impact of symptoms on the relationship with the partner, and dyspareunia. To improve these women’s lives, care should also respond to the social, emotional, and sexual issues resulting from the illness. Such interventions will contribute to improved comfort and QoL among these women.

scholarly journals Clinical and Quality of Life Outcomes among Ixekizumab Treated Psoriasis Patients in a Real-World Setting

2021 ◽  
Vol 7 (3) ◽  
pp. 1-8
Author(s):  
William N Malatestinic ◽  
Keyword(s):  
Quality Of Life ◽  
Real World ◽  
Negative Impact ◽  
Life Quality ◽  
Well Being ◽  
Skin Condition ◽  
Physician Global Assessment ◽  
Significant Negative Impact

Introduction: Psoriasis is a chronic immune-mediated inflammatory skin condition that has a significant negative impact on the physical, emotional, and psychosocial well-being of those affected. This study aimed to assess the speed of onset and long-term clinical and quality of life (QOL) outcomes among Ixekizumab (IXE) treated plaque psoriasis patients. Method: A retrospective cohort study was conducted at a single US dermatology referral center. Medical charts were reviewed for adult psoriasis patients starting IXE (index date) between March 22, 2016, and February 28, 2018.Disease severity and QOL data were collected up to one-year pre-IXE initiation and up to 35 months post-IXE initiation. Static Physician Global Assessment (sPGA), Body Surface Area (BSA), and Dermatology Life Quality Index (DLQI) were summarized at 1-month post-index and at 3-month intervals. Logistic regressions were performed to evaluate the 1-month response in relation to long-term sPGA, BSA, and DLQI outcomes. Results: A total of 153 patients (median age at index: 47.7 years; 65.4% male; 93.5% Caucasian) were included in the study. Majority of patients (69%; n=106) were biologic-experienced prior to IXE initiation. At 1-month post-index 58.8% of patients achieved sPGA (0,1), 55.9% achieved DLQI (0,1), and 66.9% achieved BSA≤1%. Patients with sPGA (0,1) at 1-month post-index had greater odds of remaining sPGA (0,1) and BSA≤1% at 24-month (sPGA 0,1: OR=10.1; 95% CI: 2.1-47.9; BSA≤1%: OR=13.3; 95% CI: 2.2-80.2). Among patients who achieved sPGA (0,1) at 1-month post-index, the observed proportion of patients with sPGA (0,1), DLQI (0,1), and BSA≤1% remained largely the same for the 24-month follow-up. Conclusion: This real-world study demonstrated that the majority of patients initiating IXE achieved sPGA (0, 1), DLQI (0, 1) and BSA ≤1% targets within the first month of treatment and were able to maintain treatment response for up to 24 months independent of prior biologic exposure.

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