scholarly journals Vine Waste Valorisation: Integrated Approach for the Prospection of Bioactive Lipophilic Phytochemicals

2019 ◽  
Vol 20 (17) ◽  
pp. 4239 ◽  
Author(s):  
Ângelo C. Salvador ◽  
Mário M. Q. Simões ◽  
Artur M. S. Silva ◽  
Sónia A. O. Santos ◽  
Sílvia M. Rocha ◽  
...  
Keyword(s):  
Dry Weight ◽  
Integrated Approach ◽  
Gas Chromatography Mass Spectrometry ◽  
Vitis Vinifera L ◽  
Grape Vine ◽  
Chemical Profiling ◽  
Waste Valorisation ◽  
Health Promoting ◽  
Integrated Study

Substantial amounts of vine wastes are produced during vineyard management, and the chemical profiling of high-value lipophilic phytochemicals is becoming crucial in order to find a complementary route towards their integrated valorisation. The prospection of bioactive phytochemicals from unripe grape, vine shoot, vine cane, stalk and leaf dichloromethane extracts was carried out by gas chromatography–mass spectrometry (GC–MS), analysing samples from a mixture of four red Vitis vinifera L. varieties (Baga, Aragonez, Água Santa and Shiraz), collected at Bairrada Appellation, as a representative case study of typical multi-variety Portuguese vineyards. Vine wastes showed distinct amounts of lipophilic extract, ranging from 0.68% (vine canes) to 13.35% (vine leaves) at dry weight (dw). Thirty-three components were identified, including fatty acids and alcohols, sterols and triterpenoids accounting for amounts from 118.9 mg/100 g dw to 1512.0 mg/100 g dw. The integrated study revealed that unripe grape, stalk and leaf dichloromethane extracts stood out as possible sources of triterpenic compounds (103.2 to 653.5 mg/100 g dw), with lupeol, ursolic and oleanolic acids prevailing. Leaf extract is also reported as an undervalued source of α-tocopherol, as the major component detected in this matrix (300.5 mg/100 g dw). These exploratory results are a relevant contribution for the exploitation of undervalued vine residues as a source of health-promoting components with the potential to be used as supplements or nutraceutical ingredients.

scholarly journals Characterizing Concealed Fault Systems by Integrating Field Data Mapping and Laboratory Experiments: A Case Study of the Huawa Area in East China

2021 ◽  
Vol 9 ◽  
Author(s):  
Huiting Hu ◽  
Shuang Hu ◽  
Rui Zhang ◽  
Xiaofei Fu ◽  
Chongyu Ren ◽  
...  
Keyword(s):  
Three Dimensional ◽  
Reference Value ◽  
Integrated Approach ◽  
East China ◽  
Fluid Distribution ◽  
Data Mapping ◽  
Series Of Experiments ◽  
Seismic Sections ◽  
Integrated Study

Concealed faults can be important for understanding the regional structural geology and the subsurface fluid distribution. However, such faults are usually difficult to identify and characterize because of their small size and complex mechanism. To address this issue, we present an integrated approach of three-dimensional seismic data mapping and physical modeling experiments to examine the geometrical and kinematic characteristics of concealed faults and their relationship with the main faults in the Huawa area, east China. Three series of experiments were designed to characterize the differences in the scale of concealed faults and main faults, which also allowed us to examine how the concealed faults grow with the main faults in the area. Through this integrated study, we have demonstrated that: 1) NE-SW-striking concealed faults are below the resolution of the available seismic datasets and not easily recognized in seismic sections and that most of them grew later than the E-W-striking main faults, with some of them having grown at the same time; 2) pre-existing faults, rather than asymmetry of the basin structure, affect the faults that develop during subsequent episodes of extension; 3) E-W-striking pre-existing faults under a NW-SE stress direction of extension are most likely the formation mechanism of concealed faults. This study is of reference value in the interpretation of concealed faults in other regions.

Commitment To Coax Subtleties From Seismic By Means Of An Intelligent Integrated Approach - A Case Study

2009 ◽  
Author(s):  
Vincent Wai Tin Kong ◽  
Alexis Carrillat ◽  
John Ross Gaither ◽  
Ahmad Bukhari Ibrahim ◽  
Irmawaty Abdullah ◽  
...  
Keyword(s):  
Integrated Approach

scholarly journals A protocol for sampling vascular epiphyte richness and abundance

2009 ◽  
Vol 25 (2) ◽  
pp. 107-121 ◽  
Author(s):  
Jan H. D. Wolf ◽  
S. Robbert Gradstein ◽  
Nalini M. Nadkarni
Keyword(s):  
Tree Height ◽  
Dry Weight ◽  
Mantel Test ◽  
Tree Size ◽  
Tree Level ◽  
Trunk Diameter ◽  
Host Trees ◽  
Epiphyte Communities ◽  
Vascular Epiphyte

Abstract:The sampling of epiphytes is fraught with methodological difficulties. We present a protocol to sample and analyse vascular epiphyte richness and abundance in forests of different structure (SVERA). Epiphyte abundance is estimated as biomass by recording the number of plant components in a range of size cohorts. Epiphyte species biomass is estimated on 35 sample-trees, evenly distributed over six trunk diameter-size cohorts (10 trees with dbh > 30 cm). Tree height, dbh and number of forks (diameter > 5 cm) yield a dimensionless estimate of the size of the tree. Epiphyte dry weight and species richness between forests is compared with ANCOVA that controls for tree size. SChao1 is used as an estimate of the total number of species at the sites. The relative dependence of the distribution of the epiphyte communities on environmental and spatial variables may be assessed using multivariate analysis and Mantel test. In a case study, we compared epiphyte vegetation of six Mexican oak forests and one Colombian oak forest at similar elevation. We found a strongly significant positive correlation between tree size and epiphyte richness or biomass at all sites. In forests with a higher diversity of host trees, more trees must be sampled. Epiphyte biomass at the Colombian site was lower than in any of the Mexican sites; without correction for tree size no significant differences in terms of epiphyte biomass could be detected. The occurrence of spatial dependence, at both the landscape level and at the tree level, shows that the inclusion of spatial descriptors in SVERA is justified.

scholarly journals Therapeutic Potentials of Syzygium fruticosum Fruit (Seed) Reflected into an Array of Pharmacological Assays and Prospective Receptors-Mediated Pathways

Life ◽  
2021 ◽  
Vol 11 (2) ◽  
pp. 155
Author(s):  
Jannatul Nasma Rupa Moni ◽  
Md. Adnan ◽  
Abu Montakim Tareq ◽  
Md. Imtiazul Kabir ◽  
A.S.M. Ali Reza ◽  
...  
Keyword(s):  
Bioactive Compounds ◽  
Integrated Approach ◽  
Gas Chromatography Mass Spectrometry ◽  
Clot Lysis ◽  
Lipinski’S Rule ◽  
Lysis Activity ◽  
In Silico Studies ◽  
Immobility Time

Syzygium fruticosum (SF), a valuable Bangladeshi fruit, is considered an alternative therapeutic agent. Mainly, seeds are used as nutritional phytotherapy to ease physical and mental status by preventing chronic diseases. Here, we scrutinized the S. fruticosum seed’s fundamental importance in traditional medicine by following an integrated approach combining in vivo, in vitro, and in silico studies. The SF was fractionated with different solvents, and the ethyl acetate fraction of SF (EaF-SF) was further studied. Mice treated with EaF-SF (200 and 400 mg/kg) manifested anxiolysis evidenced by higher exploration in elevated plus maze and hole board tests. Similarly, a dose-dependent drop of immobility time in a forced swimming test ensured significant anti-depressant activity. Moreover, higher dose treatment exposed reduced exploratory behaviour resembling decreased movement and prolonged sleeping latency with a quick onset of sleep during the open field and thiopental-induced sleeping tests, respectively. In parallel, EaF-SF significantly (p < 0.001) and dose-dependently suppressed acetic acid and formalin-induced pain in mice. Also, a noteworthy anti-inflammatory activity and a substantial (p < 0.01) clot lysis activity (thrombolytic) was observed. Gas chromatography-mass spectrometry (GC–MS) analysis resulted in 49 bioactive compounds. Among them, 12 bioactive compounds with Lipinski’s rule and safety confirmation showed strong binding affinity (molecular docking) against the receptors of each model used. To conclude, the S. fruticosum seed is a prospective source of health-promoting effects that can be an excellent candidate for preventing degenerative diseases.

scholarly journals A New Integrated Approach for Municipal Landfill Siting Based on Urban Physical Growth Prediction: A Case Study Mashhad Metropolis in Iran

2021 ◽  
Vol 13 (5) ◽  
pp. 949
Author(s):  
Salman Qureshi ◽  
Saman Nadizadeh Shorabeh ◽  
Najmeh Neysani Samany ◽  
Foad Minaei ◽  
Mehdi Homaee ◽  
...  
Keyword(s):  
Urban Growth ◽  
Integrated Approach ◽  
Physical Growth ◽  
Support Vector ◽  
Markov Chain Method ◽  
Physical Expansion ◽  
Hierarchy Process ◽  
The City

Due to irregular and uncontrolled expansion of cities in developing countries, currently operational landfill sites cannot be used in the long-term, as people will be living in proximity to these sites and be exposed to unhygienic circumstances. Hence, this study aims at proposing an integrated approach for determining suitable locations for landfills while considering their physical expansion. The proposed approach utilizes the fuzzy analytical hierarchy process (FAHP) to weigh the sets of identified landfill location criteria. Furthermore, the weighted linear combination (WLC) approach was applied for the elicitation of the proper primary locations. Finally, the support vector machine (SVM) and cellular automation-based Markov chain method were used to predict urban growth. To demonstrate the applicability of the developed approach, it was applied to a case study, namely the city of Mashhad in Iran, where suitable sites for landfills were identified considering the urban growth in different geographical directions for this city by 2048. The proposed approach could be of use for policymakers, urban planners, and other decision-makers to minimize uncertainty arising from long-term resource allocation.

scholarly journals Evaluating Life Cycle of Buildings Using an Integrated Approach Based on Quantitative-Qualitative and Simplified Best-Worst Methods (QQM-SBWM)

2021 ◽  
Vol 13 (8) ◽  
pp. 4487
Author(s):  
Maghsoud Amiri ◽  
Mohammad Hashemi-Tabatabaei ◽  
Mohammad Ghahremanloo ◽  
Mehdi Keshavarz-Ghorabaee ◽  
Edmundas Kazimieras Zavadskas ◽  
...  
Keyword(s):  
Life Cycle ◽  
Computer Software ◽  
Integrated Approach ◽  
Comfort Level ◽  
Combination Method ◽  
New Combination ◽  
Numerical Examples ◽  
Environmental Consequences ◽  
Time Required

Evaluating the life cycle of buildings is a valuable tool for assessing sustainability and analyzing environmental consequences throughout the construction operations of buildings. In this study, in order to determine the importance of building life cycle evaluation indicators, a new combination method was used based on a quantitative-qualitative method (QQM) and a simplified best-worst method (SBWM). The SBWM method was used because it simplifies BWM calculations and does not require solving complex mathematical models. Reducing the time required to perform calculations and eliminating the need for complicated computer software are among the advantages of the proposed method. The QQM method has also been used due to its ability to evaluate quantitative and qualitative criteria simultaneously. The feasibility and applicability of the SBWM were examined using three numerical examples and a case study, and the results were evaluated. The results of the case study showed that the criteria of the estimated cost, comfort level, and basic floor area were, in order, the most important criteria among the others. The results of the numerical examples and the case study showed that the proposed method had a lower total deviation (TD) compared to the basic BWM. Sensitivity analysis results also confirmed that the proposed approach has a high degree of robustness for ranking and weighting criteria.

scholarly journals A Unique Transdisciplinary Engineering-Based Integrated Approach for the Design of Temporary Refugee Housing Using Kano, HOQ/QFD, TRIZ, AD, ISM and DSM Tools

Designs ◽  
2021 ◽  
Vol 5 (2) ◽  
pp. 31
Author(s):  
Daniel Moran ◽  
Atila Ertas ◽  
Utku Gulbulak
Keyword(s):  
Rural Areas ◽  
Social Issues ◽  
Integrated Approach ◽  
Interpretive Structural Modeling ◽  
Design Problems ◽  
Design Structure ◽  
Function Design ◽  
Complex Engineering ◽  
Design Conflicts

The continued displacement of refugees from their homes and homelands (now greater than 50 million people worldwide) places increased focus and attention on evolving the designs of temporary housing that is available to be provided to the refugee population, especially in rural areas where housing does not already exist and must be constructed in very little time. Complex engineering problems involving social issues, such as this case study, benefit from the use of Integrated Transdisciplinary (TD) Tools (ITDT) to effectively and efficiently address the design questions related to them. The integrated use of TD Tools such as Kano Analysis, KJ Diagrams, Critical to Quality (CTQ), House of Quality (HOQ)/Quality Function Design (QFD), Theory of Inventive Problem Solving (TRIZ), Axiomatic Design (AD), Interpretive Structural Modeling (ISM), and Design Structure Matrix (DSM) through an end-to-end unique design process leads to innovation and elimination of design conflicts for especially complicated design problems. The objective of this study is to examine the design of temporary refugee housing using integrated TD tools mentioned above. This research concludes that the use of the ITDT approach provides an innovative, decoupled design.

scholarly journals Teacher Perspectives on Teaching the STEM Approach to Educational Coding and Robotics in Primary Education

2021 ◽  
Vol 11 (2) ◽  
pp. 64
Author(s):  
Christian García-Carrillo ◽  
Ileana María Greca ◽  
María Fernández-Hawrylak
Keyword(s):  
Primary Education ◽  
Classroom Practice ◽  
Integrated Approach ◽  
Practical Training ◽  
Training Process ◽  
Integrated Stem ◽  
Teaching Learning ◽  
And Robotics ◽  
Insight Into

An analysis is presented in this study that provides insight into a practical training process and its impact on teachers and their viewpoints toward the integrated STEM approach used in that training process, together with educational coding and robotics, over the first years of compulsory primary education, where STEM implementations are relatively new. A case study was developed by two teachers following the practical training course, including pre- and post-interviews and nonparticipative observation of their classroom practices during the teacher-training sessions. The results revealed the positive perspectives that the teachers held toward the STEM-integrated approach and educational coding and robotics, despite the difficulties that arose in classroom practice. It was concluded that the STEM approach and its methods were beneficial both to pupils and to teachers alike for improving the teaching–learning process.

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