Implant Survival in Immediately Loaded Full-Arch Rehabilitations following an Anatomical Classification System—A Retrospective Study in 1200 Edentulous Jaws

This retrospective study analyzed implant survival of immediate implant-supported fixed complete denture (IFCD) treatment options (TOs) based on the level of alveolar atrophy (CC). Records of 882 patients receiving a total of 6042 implants at one private referral clinic between 2004 and 2020 were considered. The mean follow-up period was 3.8 ± 2.7 years. Cumulative implant survival rates (CSRs) were analyzed as a function of CCs and TOs according to Mantel-Haenszel and Mantel-Cox. Hazard risk ratios for implant loss were compared using Cox regression. Confounding factors were identified using mixed Cox regression models. The 2- and 5-year CSRs were 98.2% and 97.9%, respectively. Maxillary 2- and 5-year CSRs were lower (97.7% and 97.3%) compared to mandibular CSRs (99.8% and 98.6%) (p = 0.030 and 0.0020, respectively). The CC did not influence CSRs of IFCDs in the mandible (p = 0.1483 and 0.3014, respectively) but only in the maxilla (p = 0.0147 and 0.0111), where CSRs decreased with increasing atrophy. TOs did not statistically differ in terms of survival rate for a given level of alveolar atrophy. The adaption of IFCD treatments to the level of atrophy and patient-specific risk factors can result in high CSRs, even at different levels of bone atrophy.

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Survival Rate of 1008 Short Dental Implants with 21 Months of Average Follow-Up: A Retrospective Study

Journal of Clinical Medicine ◽

10.3390/jcm9123943 ◽

2020 ◽

Vol 9 (12) ◽

pp. 3943

Author(s):

João Caramês ◽

Ana Catarina Pinto ◽

Gonçalo Caramês ◽

Helena Francisco ◽

Joana Fialho ◽

...

Keyword(s):

Retrospective Study ◽

Survival Rate ◽

Dental Implants ◽

Cox Regression ◽

Survival Rates ◽

High Survival ◽

Implant Survival ◽

Posterior Maxilla ◽

Clinical Records

This retrospective study evaluated the survival rate of short, sandblasted acid-etched surfaced implants with 6 and 8 mm lengths with at least 120 days of follow-up. Data concerning patient, implant and surgery characteristics were retrieved from clinical records. Sandblasted and acid-etched (SLA)-surfaced tissue-level 6 mm (TL6) or 8 mm (TL8) implants or bone-level tapered 8 mm (BLT8) implants were used. Absolute and relative frequency distributions were calculated for qualitative variables and mean values and standard deviations for quantitative variables. A Cox regression model was performed to verify whether type, length and/or width influence the implant survival. The cumulative implant survival rate was assessed by time-to-event analyses (Kaplan–Meier estimator). In all, 513 patients with a mean age of 58.00 ± 12.44 years received 1008 dental implants with a mean follow-up of 21.57 ± 10.77 months. Most implants (78.17%) presented a 4.1 mm diameter, and the most frequent indication was a partially edentulous arch (44.15%). The most frequent locations were the posterior mandible (53.97%) and the posterior maxilla (31.55%). No significant differences were found in survival rates between groups of type, length and width of implant with the cumulative rate being 97.7% ± 0.5%. Within the limitations of this study, the evaluated short implants are a predictable option with high survival rates during the follow-up without statistical differences between the appraised types, lengths and widths.

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PR612: Analysis of implant survival rates and implant-failure predictors: a retrospective study in a university setting

Journal Of Clinical Periodontology ◽

10.1111/jcpe.616_12915 ◽

2018 ◽

Vol 45 ◽

pp. 330-330

Keyword(s):

Retrospective Study ◽

Survival Rates ◽

Implant Failure ◽

Implant Survival ◽

University Setting

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Prognostic impact of additive chemotherapy after curative resection of metachronous colorectal liver metastasis: a single-centre retrospective study

BMC Cancer ◽

10.1186/s12885-021-07941-2 ◽

2021 ◽

Vol 21 (1) ◽

Author(s):

Matthias Kelm ◽

Julia Schollbach ◽

Friedrich Anger ◽

Armin Wiegering ◽

Ingo Klein ◽

...

Keyword(s):

Retrospective Study ◽

Curative Resection ◽

Randomized Clinical Trials ◽

Cox Regression ◽

Survival Rates ◽

Disease Free Survival ◽

Disease Recurrence ◽

Prognostic Impact ◽

Single Centre ◽

The Impact

Abstract Background A prognostic benefit of additive chemotherapy in patients following resection of metachronous colorectal liver metastases (CRLM) remains controversial. Therefore, the goal of this retrospective study was to investigate the impact of perioperative chemotherapy on disease-free survival (DFS) and overall survival (OS) of patients after curative resection of metachronous CRLM. Methods In a retrospective single-centre study, patients after curative resection of metachronous CRLM were included and analysed for DFS and OS with regard to the administration of additive chemotherapy. The Kaplan-Meier method was applied to compare DFS and OS while Cox regression models were used to identify independent prognostic variables. Results Thirty-four of 75 patients were treated with additive 5-FU based chemotherapy. OS was significantly prolonged in this patient subgroup (62 vs 57 months; p = 0.032). Additive chemotherapy significantly improved 10-year survival rates (42% vs 0%, p = 0.023), but not 5-year survival (58% vs 42%, p = 0.24). Multivariate analysis identified additive chemotherapy (p = 0.016, HR 0.44, 95% CI 0.23–0.86), more than five CRLM (p = 0.026, HR 2.46, 95% CI 1.16–10.32) and disease recurrence (0.009, HR 2.70, 95% CI 1.29–5.65) as independent risk factors for OS. Conclusion Additive chemotherapy significantly prolonged OS and 10-year survival in patients after curative resection of metachronous CRLM. Randomized clinical trials are needed in the future to identify optimal chemotherapy regimens for those patients.

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A Three-Year Retrospective Study on Survival of Ceramic-Veneered Zirconia (Y-TZP) Fixed Dental Prostheses Performed in Private Practices

International Journal of Dentistry ◽

10.1155/2017/9618306 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 2

Author(s):

Veronika Norström Saarva ◽

Göran Bjerkstig ◽

Anders Örtorp ◽

Per Svanborg

Keyword(s):

Retrospective Study ◽

Cox Regression ◽

Survival Rates ◽

Promising Alternative ◽

Private Practices ◽

Dental Prostheses ◽

Kaplan Meier ◽

Metal Ceramic ◽

Fixed Dental Prostheses ◽

Posterior Area

Objectives. The aim of this retrospective study was to evaluate the three-year clinical outcome for ceramic-veneered zirconia fixed dental prostheses (FDPs). Methods. All patients who were treated with ceramic-veneered zirconia FDPs, in three private practices in Sweden, during the period June 2003 to April 2007 were included. Case records from 151 patients, treated with a total of 184 zirconia FDPs (692 units), were analysed for clinical data. All complications noted in the charts were registered and compared to definitions for success and survival and statistical analysis was performed using the Kaplan-Meier method and a Cox regression model. Results. In total, 32 FDPs in 31 patients experienced some type of complication (17.4% of FDPs, 20.5% of patients). Core fractures occurred in two (1.1%) FDPs. Two (1.1%) FDPs or 0.6% of units showed adhesive veneer fractures. Cohesive veneer fractures occurred in 10 (5.4%) FDPs (1.6% of units). The three-year cumulative success and survival rates (CSR) were 82.3% and 95.2%, respectively. Conclusions. Ceramic-veneered zirconia is a promising alternative to metal-ceramic FDPs, even in the posterior area. However, the higher survival rate of metal-ceramic FDPs should be noted and both dentists and patients must be aware of the risks of complications.

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Effects of Red Blood Cell Transfusions on Distant Metastases of Oral Squamous Cell Carcinomas

Cancers ◽

10.3390/cancers14010138 ◽

2021 ◽

Vol 14 (1) ◽

pp. 138

Author(s):

Leonard Simon Brandenburg ◽

Marc Christian Metzger ◽

Philipp Poxleitner ◽

Pit Jacob Voss ◽

Kirstin Vach ◽

...

Keyword(s):

Surgical Treatment ◽

Blood Cell ◽

Squamous Cell ◽

Red Blood Cell ◽

Cox Regression ◽

Cox Model ◽

Univariate Analysis ◽

Survival Rates ◽

Distant Metastases ◽

Patient Specific

There is no consensus on the effect of red blood cell (RBC) transfusions on patients with oral squamous cell carcinoma (OSCC). The aim of this study was to investigate the association between RBC administration and the occurrence of distant metastases (M+) after surgical treatment of OSCC. All medical records of patients who underwent primary surgery for OSCC in our department (2003–2019) were analyzed retrospectively (n = 609). Chi and Cox regression models were used to analyze the influence of transfusion on the development of M+, and survival rates. Kaplan–Meier curves were used for graphical presentation. A multitude of patient-specific factors showed a statistical impact in univariate analysis (transfusion, age, gender, diabetes, pT, pN, L, V, Pn, G, UICC, adjuvant therapy, free microvascular transplant, preoperative hemoglobin level). Transfusion status and pN stage were the only variables that showed a significant correlation to M+ in the multivariate Cox model. The hazard ratios for the occurrence of M+ were 2.42 for RBC transfusions and 2.99 for pN+. Administration of RBC transfusions was identified as a significant prognostic parameter for the occurrence of distant metastases after surgical treatment of OSCC. Hence, the administration of RBC transfusions should be considered carefully in the perioperative management.

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Sinus Grafting With a Natural Flourohydroxyapatite for Immediate Load: A Study With Histologic Analysis and Histomorphometry

Journal of Oral Implantology ◽

10.1563/1548-1336-35.4.164 ◽

2009 ◽

Vol 35 (4) ◽

pp. 164-175 ◽

Cited By ~ 11

Author(s):

Cameron Y. S. Lee ◽

Michael D. Rohrer ◽

Hari S. Prasad ◽

John D. Stover ◽

Jon B. Suzuki

Keyword(s):

Retrospective Study ◽

Dental Implants ◽

Platelet Rich Plasma ◽

Survival Rates ◽

Bone Sample ◽

Autogenous Bone ◽

Osteotomy Site ◽

Graft Material ◽

Implant Survival ◽

Posterior Maxilla

Abstract The goal of this retrospective study was to evaluate the survival rates of dental implants placed in sinuses grafted with a 50:50 composite ratio of autogenous bone and a natural flourohydroxyapatite (FHA) combined with platelet-rich plasma (PRP) using an immediate-load protocol. The authors hypothesized that a 50:50 composite ratio of FHA and autogenous bone combined with PRP would permit immediate loading without compromising implant survival rates. Eleven patients with bilateral partial edentulism of the posterior maxilla were enrolled in this retrospective study. Autogenous bone used in the graft procedure was harvested from the tibia of the left lower extremity. Each patient was grafted with a 50:50 composite ratio of autogenous bone and FHA. Membranes were not used to cover the lateral wall osteotomy site. Platelet-rich plasma was added to the graft material to accelerate and enhance bone regeneration. Four to 6 months after the grafting procedure, 37 hydroxyapatite-coated dental implants were surgically placed and immediately loaded between 72 hours and 5 days later with custom titanium abutments and acrylic provisional restorations placed out of functional occlusion. Six months later, definitive ceramometal restorations were cemented on to the custom abutments. Patients were observed over a 52-week period. The overall implant survival rate was 97.3%. Histologic and histomorphometric analysis of core samples revealed formation of new vital bone in different graft specimens ranging from 23% to 34%. In each core bone sample, 100% of the bone sample was determined to be vital. In the grafted maxillary sinus, the natural FHA combined with autogenous bone in a 50:50 composite ratio with PRP is a suitable graft material permitting immediate load without compromising implant survival rates while decreasing the overall healing time.

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Clinical Performance of Implant Crown Retained Removable Partial Dentures for Mandibular Edentulism—A Retrospective Study

Journal of Clinical Medicine ◽

10.3390/jcm10102170 ◽

2021 ◽

Vol 10 (10) ◽

pp. 2170

Author(s):

Soo-Yeon Yoo ◽

Seong-Kyun Kim ◽

Seong-Joo Heo ◽

Jai-Young Koak ◽

Hye-Rin Jeon

Keyword(s):

Retrospective Study ◽

Bone Loss ◽

Clinical Performance ◽

Survival Rates ◽

Treatment Modalities ◽

Implant Survival ◽

Marginal Bone Loss ◽

Final Recall ◽

Patient Reported ◽

Implant Crown

The studies on implant-crown-retained removable partial dentures (IC-RPDs) for edentulism are scarce. The purpose of this study was to evaluate survival rates and marginal bone loss (MBL) of IC-RPDs compared to implant overdentures (IODs) in mandibular edentulism. Variables that influenced survival and marginal bone loss (MBL) of implants in both treatment modalities were analyzed and the functional/esthetic satisfaction of patients as well as prosthetic complications were also observed. Eighteen IC-RPDs with a total of 60 implant-supported survey crowns and 24 IODs with a total 94 implants retained with magnet attachments were observed. After a median observation period of 46.6 months (up to 149 months), we observed 98.3% implant survival rates for IC-RPDs and 92.5% for IODs. Kaplan–Meier survival curves based on the treatment modality showed that, at 96 months, cumulative survival rates were 98.3% in IC-RPD and 83.1% in IOD. For implant survival rates, no statistical differences were observed according to age, sex, opposing dentition, or implant positions (p = 0.515, 0.666, 0.201, 0.749, respectively). The implant MBL measurements for IC-RPD and IOD groups at the final recall check were 0.93 ± 1.22 mm and 2.12 ± 2.09 mm, respectively. Additionally, there were no significant differences between groups (p = 0.554). The implants with peri-implantitis at year 1 showed significantly higher MBL at final check-up (p < 0.001). The MBL of implants showed significant differences based on age (p = 0.008) and opposing dentition (p = 0.003). No significant differences of implant MBL were observed for the position of placed implants (p = 0.621) or sex (p = 0.666). Patient-reported outcome measures (PROMs) on functional and esthetic satisfaction were significantly improved after IC-RPD or IOD treatment (p < 0.001). The most frequent prosthetic complication of IC-RPD was clasp loosening, while for IOD group, it was attachment dislodgement. Within the limitations of this retrospective study, we concluded that IC-RPDs could be considered as a viable treatment option for edentulous patients who need few fixed abutments for satisfaction.

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