scholarly journals The Complex Relationship Between Serum Uric Acid, Endothelial Function and Small Vessel Remodeling in Humans

2020 ◽  
Vol 9 (7) ◽  
pp. 2027
Author(s):  
Stefano Masi ◽  
Georgios Georgiopoulos ◽  
George Alexopoulos ◽  
Konstantinos Pateras ◽  
Javier Rosada ◽  
...  
Keyword(s):  
Uric Acid ◽  
Endothelial Function ◽  
Serum Uric Acid ◽  
Structural Equation ◽  
Equation Modeling ◽  
Cross Sectional ◽  
Heart Score ◽  
Additional Information ◽  
Microvascular Remodeling ◽  
The Relationship

Aims: The relationship between serum uric acid (SUA) and microvascular remodeling in humans remains largely unexplored. We assessed whether SUA provides additional information on the severity of microvascular remodeling than that obtained from the European Heart Score (HS), the patterns of microvascular remodeling associated with changes in SUA levels and the mediation by endothelial function and nitric oxide (NO) availability on this relationship. Methods: A total of 162 patients included in the microvascular dataset of the Italian Society of Hypertension with available information on SUA, media-to-lumen (M/L) ratio, media cross-sectional area (MCSA), endothelial function, NO availability and HS were included in the analysis. The top tertile of M/L ratio and MCSA were used to define severe microvascular remodeling. Results: A U-shaped association was observed between SUA and both M/L ratio and MCSA. Adjustment for HS did not affect these associations. SUA was able to reclassify a significant number of subjects without, and with, severe M/L ratio and MCSA remodeling over the HS alone. The microvascular remodeling associated with SUA levels presented a predominant hypertrophic pattern. SUA was inversely associated with endothelial function and NO availability. Structural equation modeling analysis controlling for the HS suggested that the association of SUA with M/L ratio and MCSA was mediated through changes in endothelial function and NO availability. Conclusions: The addition of SUA to the HS improves the identification of subjects with greater microvascular remodeling. The relationship between SUA and microvascular remodeling is mediated by endothelial function and NO availability.

scholarly journals Perceived discrimination and psychological distress among immigrants to Canada: The mediating role of bicultural identity orientations

2021 ◽  
pp. 136843022199008
Author(s):  
Mustafa Firat ◽  
Kimberly A. Noels
Keyword(s):  
Psychological Distress ◽  
Undergraduate Students ◽  
Structural Equation ◽  
Perceived Discrimination ◽  
The Other ◽  
Equation Modeling ◽  
Bicultural Identity ◽  
Cross Sectional ◽  
Mediating Role ◽  
The Relationship

Bicultural identity orientations have rarely been examined in relation to both perceived discrimination and psychological distress. Furthermore, these constructs have usually been studied in isolation, but their intersection is essential for understanding intercultural relations in multicultural societies. Using cross-sectional data from 1,143 Canadian undergraduate students from immigrant families, this study explored the relationship between perceived discrimination and psychological distress, and how bicultural identity orientations might mediate this relationship. The structural equation modeling results indicated that perceived discrimination was associated with higher levels of psychological distress and hybrid, monocultural, alternating, and conflicted orientations, but lower levels of complementary orientation. Alternating and conflicted orientations were related to higher psychological distress, whereas the other orientations were not. Alternating and conflicted orientations mediated the relationship between perceived discrimination and psychological distress, whereas the other orientations did not. The findings are discussed in light of theories on identity integration, rejection–identification, and acculturation.

Serum uric acid levels and risk of prehypertension: a meta-analysis

2017 ◽  
Vol 55 (3) ◽  
Author(s):  
Menglin Jiang ◽  
Dandan Gong ◽  
Yu Fan
Keyword(s):  
Uric Acid ◽  
Serum Uric Acid ◽  
Meta Analysis ◽  
Elevated Serum ◽  
China National Knowledge Infrastructure ◽  
Cross Sectional ◽  
Knowledge Infrastructure ◽  
Increased Risk ◽  
Cross Sectional Studies ◽  
The Relationship

AbstractElevated serum uric acid (SUA) levels may increase the risk of prehypertension. However, the findings from these studies remain conflicting. The objective of this study was to determine the relationship between SUA levels and risk of prehypertension by conducting a meta-analysis. We conducted a comprehensive literature search of PubMed, Embase, China National Knowledge Infrastructure, VIP, and the Wangfang database without language restrictions through May 2015. Observational studies assessing the relationship between SUA levels and prevalence of prehypertension were included. Pooled adjust odds ratio (OR) and corresponding 95% confidence intervals (CI) of prehypertension were calculated for the highest vs. lowest SUA levels. Prehypertension was defined as systolic blood pressure (BP) ranging from 120 to 139 mmHg or diastolic BP ranging from 80 to 89 mmHg. Eight cross-sectional studies with a total of 21,832 prehypertensive individuals were included. Meta-analysis showed that elevated SUA levels were associated with increased risk of prehypertension (OR: 1.84; 95% CI: 1.42–2.38) comparing the highest vs. lowest level of SUA levels. Subgroup analyses showed that elevated SUA levels significantly increased the risk of prehypertension among men (OR: 1.60; 95% CI: 1.12–2.21) and women (OR: 1.59; 95% CI: 1.17–2.16). Elevated SUA levels are positively associated with the risk of prehypertension in the general population. However, more well-designed longitudinal studies are needed before a definitive conclusion can be drawn due to the cross-sectional studies included are susceptible to bias.

scholarly journals Stereotype threat and older worker’s attitudes: a mediation model

2018 ◽  
Vol 47 (1) ◽  
pp. 187-205 ◽  
Author(s):  
Eduardo Oliveira ◽  
Carlos Cabral Cardoso
Keyword(s):  
Stereotype Threat ◽  
Older Workers ◽  
Structural Equation ◽  
Work Attitudes ◽  
Equation Modeling ◽  
Mediation Model ◽  
Cross Sectional ◽  
Content Type ◽  
Negative Work ◽  
The Relationship

Purpose Taking a social identity approach, the purpose of this paper is to examine the extent to which age-based stereotype threat mediates the relationships between older workers’ negative age-based metastereotypes and two negative work attitudes: organizational disidentification and work disengagement. Design/methodology/approach A two-wave cross-sectional design was adopted to collect data from 423 blue-collar older workers of the Portuguese manufacturing sector. Structural equation modeling was used to test the mediation model. Findings The analyses show that age-based stereotype threat partially mediates the relationship between negative age-based metastereotypes and negative work attitudes. Moreover, findings suggest that older workers respond to negative age-based metastereotypes through threat reactions, and undesirable work attitudes. Originality/value This paper contributes to the literature by showing the importance of negative age-based metastereotypes and age-based stereotype threat in workplace dynamics. It also provides evidence that age threats impair the relationship older workers keep with their organization and their work.

scholarly journals Psychological Capital and Family Satisfaction among Employees: Do Occupational Stressors Moderate the Relationship?

2021 ◽  
Vol 18 (22) ◽  
pp. 12260
Author(s):  
Oi-Ling Siu ◽  
Qianting Kong ◽  
Ting-Kin Ng
Keyword(s):  
Structural Equation ◽  
Online Survey ◽  
Psychological Capital ◽  
Positive Association ◽  
Family Satisfaction ◽  
Equation Modeling ◽  
Occupational Stressors ◽  
Cross Sectional ◽  
Personal Resource ◽  
The Relationship

The COVID-19 pandemic has created more occupational stressors, particularly work–family interface issues. The purpose of this study was to investigate the moderating role of occupational stressors in the relationship between a personal resource (psychological capital) and family satisfaction. A cross-sectional study was carried out with a sample of 787 employees (367 males, 420 females) from the Greater Bay Area of China between October and November 2020. Participants completed an online survey which included the Chinese version of the Psychological Capital Questionnaire, measures of occupational stressors from the Work Stress Management DIY Kit and a measure of family satisfaction. Latent moderated structural equation modeling revealed that family satisfaction was positively associated with psychological capital and negatively associated with occupational stressors. Furthermore, occupational stressors weakened the positive association between psychological capital and family satisfaction. These findings provided empirical evidence for the work–home resources model and may suggest that it would be beneficial to boost psychological capital and reduce occupational stressors of employees.

The individual side of ambidexterity

2019 ◽  
Vol 41 (3) ◽  
pp. 592-613 ◽  
Author(s):  
Andrés Salas Vallina ◽  
Maria D. Moreno-Luzon ◽  
Anna Ferrer-Franco
Keyword(s):  
Structural Equation ◽  
Public Hospitals ◽  
Equation Modeling ◽  
Exploration And Exploitation ◽  
Cross Sectional ◽  
Learning Capability ◽  
Content Type ◽  
Individual Level ◽  
The Individual ◽  
The Relationship

PurposeThe purpose of this paper is twofold: first, to examine whether inspirational leadership of heads of specialized medical units is related to individual ambidexterity of their dependent physicians; and second, to study the possible mediating role of organizational learning capability (OLC) in the relationship between inspirational leadership and individual ambidexterity.Design/methodology/approachStructural equation modeling was used on a sample of 194 medical specialists from Spanish public hospitals.FindingsResults show that inspirational leadership is positively related to individual ambidexterity among healthcare physicians. In addition, the results of the study revealed that the relationship between inspirational leadership and individual ambidexterity is mediated by conditions that facilitate learning, namely, OLC.Research limitations/implicationsThis study uses cross-sectional data, which do not guarantee causality relationships among the examined variables.Practical implicationsThe results of this paper suggest first that heads of healthcare units should inspire followers to achieve both exploration and exploitation. Second, it is also necessary to consider that inspirational leaders promote those conditions that facilitate learning, which should be particularly taken into account to enhance both physician’s exploration and exploitation.Originality/valueIn stressing an evident gap in the relationship between leadership and ambidexterity at the individual level, this paper attempts to advance in the leadership literature by revealing how the action or power of moving the intellect or emotions, and enhancing enthusiasm and confidence, empowers physicians to both explore and exploit knowledge. The results also indicate that the inspiration transmitted by the heads of medical services, facilitate physician’s perceived learning conditions which, in turn, fosters their individual ambidexterity.

scholarly journals Reporting Skill: The Missing Ingredient in Concussion Reporting Intention Assessment

2019 ◽  
Vol 11 (5) ◽  
pp. 416-424 ◽  
Author(s):  
Dee Warmath ◽  
Andrew P. Winterstein
Keyword(s):  
Structural Equation ◽  
Age Groups ◽  
Cross Sectional Study ◽  
Equation Modeling ◽  
Level Of Evidence ◽  
Cross Sectional ◽  
Confirmatory Factor Analyses ◽  
Concussion Knowledge ◽  
The Relationship ◽  
Reporting Intentions

Background: Extant literature suggests that a substantial portion of athletes may not report a possible concussion and that concussion knowledge is insufficient to predict concussion reporting behavior. One area that has not been explored is reporting skill; that is, mastery of the actions required to report a concussion. This study evaluated the relationship between reporting skill and reporting intention, introducing a measure of the reporting skill construct. Hypotheses: Reporting intentions will be more closely associated with reporting skill than with concussion/symptom knowledge. The relationship between concussion (or symptom) knowledge and reporting intentions will differ by level of reporting skill. Study Design: Repeated cross-sectional study. Level of Evidence: Level 2. Methods: A set of items was administered to young adults aged 18 to 24 years from the Survey Sampling International panel. Exploratory/confirmatory factor analyses were conducted on 2 waves of data to develop the scale (n = 899). Hypotheses were tested using structural equation modeling on the responses from the third wave of participants (n = 406). Results: Knowing the actions to take in reporting was more important than having knowledge of concussions or concussion symptoms. Reporting skill, not concussion or concussion symptom knowledge, was associated with higher intentions to report symptoms. Among those with higher levels of reporting skill, concussion symptom knowledge (but not general concussion knowledge) was associated with higher intentions to report symptoms. Conclusion: Reporting skill is an important and, until now, missing ingredient in the concussion literature and practice. Clinical Relevance: Incorporating reporting skill development in concussion education and team activities to teach athletes how to report is likely to improve actual reporting intentions. While further study is needed with particular sports and additional age groups, reporting skill holds promise as a new avenue for increased concussion reporting.

Sexualization of the work environment and emotional exhaustion

2019 ◽  
Vol 40 (4) ◽  
pp. 558-573
Author(s):  
Hong T.M. Bui ◽  
Jonathan Pinto ◽  
Abhishek Srivastava
Keyword(s):  
Work Environment ◽  
Emotional Exhaustion ◽  
Structural Equation ◽  
Negative Impact ◽  
High Rate ◽  
Dark Side ◽  
Equation Modeling ◽  
Cross Sectional ◽  
Content Type ◽  
The Relationship

Purpose The purpose of this paper is to explore the relationship between sexualization of the work environment and emotional exhaustion, and develop some key antecedents of sexualization of the work environment. It was conducted in an emerging society, India, which has a high rate of crime against women, particularly related to sexual harassment and sexual assault. Design/methodology/approach To test the hypotheses, structural equation modeling was performed. The hypotheses were tested with data from 1,098 white collar workers in India in three ways. Findings Contact with other gender and flexible work arrangements were positively associated with sexualization of the work environment; and sexualization of the work environment was positively associated with emotional exhaustion. In addition, sexualization of the work environment mediated the relationship between the two antecedent variables and emotional exhaustion. Research limitations/implications There is a possible bias arising from the use of cross-sectional data. However, a number of methods were implemented to minimize it, including survey design and data analysis. Practical implications The study offers some important suggestions for workplaces with a greater proportion of young male employees, particularly in a societal context like India. Originality/value The paper provides evidence of the negative impact of sexualization of the work environment, and thereby contributes to current understanding of the “dark side” of behavior at work that might have significant impact on society.

The relationship between cultural intelligence and i-deals

2016 ◽  
Vol 24 (5) ◽  
pp. 908-931 ◽  
Author(s):  
Tuan Trong Luu ◽  
Chris Rowley
Keyword(s):  
Structural Equation ◽  
Cultural Intelligence ◽  
Equation Modeling ◽  
Cross Sectional ◽  
Content Type ◽  
Knowledge Based ◽  
Synergy Effects ◽  
Business Setting ◽  
Identity Based ◽  
The Relationship

Purpose Cultural intelligence is the capacity to decode and harmonize with another culture for cultural synergy effects. This paper aims to examine whether cultural intelligence can activate idiosyncratic deals (i-deals) through trust as a mediator and HR localization as a moderator. Design/methodology/approach Cross-sectional data from respondents from joint ventures or 100 per cent foreign-invested firms in Vietnam business setting, which were tested through the structural equation modeling, provide the evidence for the research model. Findings Research results confirmed the positive effect of cultural intelligence on identity-based trust and knowledge-based trust, which in turn influence i-deals. HR localization was also found to play a moderating role on the relationship between identity-based trust or knowledge-based trust and i-deals. Originality/value Cultural intelligence literature, from this study, is further deepened through its role as a trigger for the path from cultural intelligence to i-deals.

scholarly journals Work Intention as Mediator in the Relationship between Work Passion and Organizational Commitment among Teachers in Malaysia

2019 ◽  
Vol 8 (2S10) ◽  
pp. 102-110
Keyword(s):  
Organizational Commitment ◽  
Structural Equation ◽  
Sampling Technique ◽  
Equation Modeling ◽  
Cluster Sampling ◽  
School Teachers ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
The Relationship ◽  
Work Passion

Organizational commitment among employees is important to determine organizational effectiveness as employees with higher organizational commitment have higher motivation to stay with their organization. In recent years, previous studies have shown that the teachers’ organizational commitment are low and moderate. Therefore, this study focuses on the effect of work passion toward organizational commitment with work intention as the mediator. The objectives of this study was to determine the effect of work passion on work intention and organizational commitment among teachers and to determine the role of work intention as a mediator in the effect of work passion on organizational commitment among teachers. This study employed a cross-sectional survey involving 355 school teachers in Malaysia through multi-stage cluster sampling technique. Data were analyzed using descriptive analysis, while confirmatory factor analysis (CFA) and structural equation modeling (SEM) were used to determine the fitness of the model with the data. Findings showed that organizational commitment and work passion among school teachers were moderate, while work intention was at a higher level. SEM analysis showed that the model has a good fit with CMIN/df= 3.22, GFI = 0.95, CFI=0.97, TLI=0.95, RMSEA=0.08. In addition, job factors have a significant direct effect on work intention and organizational commitment. Results also showed that work intention mediated the relationship between work passion and organizational commitment. The results of this imply the importance of work passion and work intention in enhancing organizational commitment among teachers in Malaysia.

Sign in / Sign up

Export Citation Format

Share Document