scholarly journals Altered Gut Microbiota in Irritable Bowel Syndrome and Its Association with Food Components

2021 ◽  
Vol 11 (1) ◽  
pp. 35
Author(s):  
Zahra A. Barandouzi ◽  
Joochul Lee ◽  
Kendra Maas ◽  
Angela R. Starkweather ◽  
Xiaomei S. Cong
Keyword(s):  
Irritable Bowel Syndrome ◽  
Gut Microbiota ◽  
Alpha Diversity ◽  
Diversity Indices ◽  
Cross Sectional Study ◽  
Caffeine Intake ◽  
Caffeine Consumption ◽  
Cross Sectional ◽  
Food Components ◽  
Irritable Bowel

The interplay between diet and gut microbiota has gained interest as a potential contributor in pathophysiology of irritable bowel syndrome (IBS). The purpose of this study was to compare food components and gut microbiota patterns between IBS patients and healthy controls (HC) as well as to explore the associations of food components and microbiota profiles. A cross-sectional study was conducted with 80 young adults with IBS and 21 HC recruited. The food frequency questionnaire was used to measure food components. Fecal samples were collected and profiled by 16S rRNA Illumina sequencing. Food components were similar in both IBS and HC groups, except in caffeine consumption. Higher alpha diversity indices and altered gut microbiota were observed in IBS compared to the HC. A negative correlation existed between total observed species and caffeine intake in the HC, and a positive correlation between alpha diversity indices and dietary fiber in the IBS group. Higher alpha diversity and gut microbiota alteration were found in IBS people who consumed caffeine more than 400 mg/d. Moreover, high microbial diversity and alteration of gut microbiota composition in IBS people with high caffeine consumption may be a clue toward the effects of caffeine on the gut microbiome pattern, which warrants further study.

scholarly journals Irritable Bowel Syndrome Among University Students in Jordan

2019 ◽  
Author(s):  
Amjad Al-Shdaifat ◽  
Anwar Al-Kassar ◽  
Asgeir Johannessen ◽  
Zaid Al-Dabbagh ◽  
Mohamed Al-Ethawi ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
University Students ◽  
Multivariable Analysis ◽  
Cross Sectional Study ◽  
Poor Sleep ◽  
Rome Iii Criteria ◽  
Cross Sectional ◽  
Rome Iii ◽  
Irritable Bowel ◽  
Hashemite University

Abstract Background Irritable bowel syndrome (IBS) is one of the commonest diagnosed gastrointestinal disorders (GI) in primary care and gastroenterology practices. This study aimed to explore the prevalence of IBS, and identify associated factors, among university students in Jordan. Methods A cross-sectional study was conducted among students at the Hashemite University in Jordan. A validated, confidential, self-administered data collection questionnaire was used for the collection of personal and sociodemographic data, and the Rome III criteria were used to define IBS. Logistic regression analysis was done to identify factors associated with IBS. Results A total of 198 students participated in the study, of whom 163 had complete data and could be assessed by the Rome III criteria. The age range of the students was 18 to 35 years, and 91 (55.8%) were women. Overall, 26 (16.0%) of the respondents were diagnosed with IBS. Poor sleep (Adjusted Odds Ratio [AOR] 3.9; 95% confidence interval [CI] 1.5-10.4; p<0.01), being married (AOR 7.6; 95% CI 2.0-28.8; p<0.01) and a family history of IBS (AOR 2.9; 95% CI 1.1-7.7; p=0.03) were independently associated with IBS in multivariable analysis. Conclusion IBS was common among otherwise healthy university student in Jordan. Lifestyle factors such as poor sleep appeared to be associated with IBS symptoms.

scholarly journals Predictive value of alarm symptoms in Rome IV irritable bowel syndrome: A multicenter cross-sectional study

2022 ◽  
Vol 10 (2) ◽  
pp. 563-575
Author(s):  
Qian Yang ◽  
Zhong-Cao Wei ◽  
Na Liu ◽  
Yang-Lin Pan ◽  
Xiao-Sa Jiang ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Predictive Value ◽  
Cross Sectional Study ◽  
Sectional Study ◽  
Cross Sectional ◽  
Irritable Bowel ◽  
Rome Iv

scholarly journals Prevalence of Organic Colonic Lesions by Colonoscopy in Patients Fulfilling ROME IV Criteria of Irritable Bowel Syndrome

2018 ◽  
Vol 56 (209) ◽  
pp. 487-492 ◽  
Author(s):  
Mukesh Sharma Paudel ◽  
Amrendra Kumar Mandal ◽  
Barun Shrestha ◽  
Nandu Silwal Poudyal ◽  
Sudhamshu KC ◽  
...  
Keyword(s):  
Irritable Bowel Syndrome ◽  
Histopathological Examination ◽  
Malignant Lesion ◽  
Recurrent Abdominal Pain ◽  
Cross Sectional Study ◽  
Cross Sectional ◽  
Irritable Bowel ◽  
Histopathology Examination ◽  
Rome Iv ◽  
Organic Lesions

Introduction: Irritable bowel syndrome occurs as recurrent abdominal pain that is related to defecation and associated with change in frequency and/or form of stool. Few Patients with IBS may have organic lesions detectable at colonoscopy. Methods: A cross sectional study was carried out in 140 consecutive patients of IBS fulfilling the ROME IV criteria. The study was conducted in Gastroenterology unit, Department of Medicine, Bir hospital, Kathmandu from July 2016 to September 2017. All patients underwent full colonoscopy along with biopsy from sigmoid colon and any visibly abnormal areas. Results: The average age of patients was 37.5 years with 76 (52.8%) males. Forty-two (30%) had IBS-D, 36 (26%) had IBS-C, 31 (22%) had IBS-M and 31 (22%) had IBS-U. Dyspepsia was seen in 16 (11.4%) and fear of TB/Malignancy/IBD was seen in 27 (19.2%). Organic lesions were seen in 39 (27.85%) patients. Nonspecific colitis was seen in 10 (7.1%) followed by ileal erosions in 7 (5%), polyps in 8 (5.7%), hemorrhoids in 6 (4.2%) and diverticula in 3 (2.1%). Only one (0.71%) patient had microscopic colitis and one (0.71%) had malignant lesion seen at histopathological examination. Females with IBS-D had more organic findings than males (P=0.03, RR=4.13, 95% CI=1.21-15.71). Conclusions: The prevalence of organic lesions in patients with IBS fulfilling ROME IV criteria is 27%. Dyspepsia is the most common comorbidity and fear of TB/malignancy/IBD is the most common reason for seeking health care. Females with IBS-D have a higher risk of detecting organic lesions by colonoscopy and histopathology examination.

scholarly journals Assessment of the levels of caffeine consumption among Saudi Arabian university students

2021 ◽  
Vol 8 (3) ◽  
pp. 36-39
Author(s):  
Sami Abdulrahman Alhamidi ◽  
◽  
Seham Mansour Alyousef ◽  
Keyword(s):  
Nursing Students ◽  
University Students ◽  
Undergraduate Students ◽  
Saudi Arabian ◽  
Cross Sectional Study ◽  
Caffeine Intake ◽  
Caffeine Consumption ◽  
Cross Sectional ◽  
Undergraduate Nursing ◽  
Typical Day

This study aimed to assess the caffeine consumption of Saudi Arabian undergraduate students and to determine if the average amount consumed is within healthful parameters. Caffeine consumption in Saudi Arabia is a major cultural and social feature. Consumption of excessive amounts of caffeine can be deleterious to the health of university students. This is a cross-sectional study. A total of 145 male undergraduate nursing students were surveyed using the Caffeine Consumption Questionnaire to assess their caffeine intake on a typical day. Among this group, 34.5% of students exceeded the 400mg daily safe levels for caffeine consumption. The average consumption of the total group, those consuming below 400mg and those exceeding 400mg were 325.1, 201.2, and 570.1 mg, respectively. Tea and coffee were the major contributors to total caffeine intake ranging from 0-8 (240ml) servings per day. Health promotion aimed at illuminating health risks of caffeine consumption exceeding safe limits may assist in modification of intake to more healthful levels.

The relationship of caffeinated beverages with depressive symptoms and decision-making

2021 ◽  
pp. 1-10
Author(s):  
Hatice Çolak ◽  
Emel Erdeniz ◽  
Esra Tansu Sarıyer ◽  
Ekin Çevik ◽  
Didem Yangın
Keyword(s):  
Decision Making ◽  
Depressive Symptoms ◽  
Linear Regression Analysis ◽  
Cross Sectional Study ◽  
Caffeine Intake ◽  
Caffeine Consumption ◽  
Cross Sectional ◽  
Decision Making Styles ◽  
Intuitive Decision Making ◽  
The Relationship

BACKGROUND: Caffeine can affect depressive symptoms and decision-making. OBJECTIVE: This study aims to examine the relationship between caffeinated beverages consumption with depressive symptoms and decision-making styles. METHODS: This cross-sectional study was conducted with 432 adults working in office environment. The questionnaire consisting of individuals’ socio-demographic attributes, the frequency and the amount of caffeinated beverages consumption, the “Epidemiological Research Center-Depression (CES-D) Scale” and the “Decision-Making Styles Scale” were used. The frequency and amount of caffeinated beverages were determined using the food frequency questionnaire (FFQ). The participants were asked to choose which cup/mug they prefer to drink their caffeinated beverages and what amount they consume that beverage at a time. All the data were collected using online platforms. RESULTS: In the study, 76.7%of the participants were female and the mean age was 31.5±8.0 years. The average daily total caffeine intake of the participants was 425.8±461.4 mg and the total CES-D scale score was 17.7±11.2 points. It was found that as the amount of caffeine consumed increased, intuitive decision-making decreased and depressive symptoms increased (p <  0.05). In linear regression analysis, total caffeine consumption was found to be a significant predictor for the intuitive decision-making score (B: –0.151; p:0.002). When caffeine consumption is controlled, intuitive and rational decision making decreases with increasing depressive symptoms while addiction and avoidance decision making increased (p <  0.05). CONCLUSIONS: As a result, the amount of caffeine consumed daily was related to intuitive decision-making but did not effect depression. It has been observed that depressive symptoms affect decision-making styles in different ways. To our knowledge, our study is the first to examine the effects of caffeine consumption on depression and decision-making styles. Accordingly, future studies may focus on the link between caffeine consumption, depression, and decision-making styles in larger populations and the mechanisms that influence this relationship.

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