scholarly journals Association of Prenatal Maternal Anemia with Tics and Tourette’s Syndrome in Offspring

2021 ◽  
Vol 11 (10) ◽  
pp. 1038
Author(s):  
Yi-Chun Liu ◽  
Vincent Chin-Hung Chen ◽  
Yin-To Liao ◽  
Yi-Lung Chen
Keyword(s):  
Iron Deficiency ◽  
Gestational Age ◽  
Low Income ◽  
Tourette's Syndrome ◽  
Deficiency Anemia ◽  
Tourette’S Syndrome ◽  
Research Database ◽  
Maternal Anemia ◽  
Increased Risk ◽  
The Relationship

Iron deficiency anemia (IDA) accounts for most of the anemia in pregnancy, and iron is essential for neurodevelopment. Tics and Tourette’s syndrome (TS) are neurodevelopmental disorders that manifest in childhood. A few studies reported an inconclusive association between iron deficiency and tics in children. No study has investigated the relationship between prenatal maternal anemia and tics in children. We aimed to assess the relationship between prenatal anemia exposure and the incidence of tics or TS in offspring. We linked the Taiwan National Health Insurance Research Database to the Maternal and Child Health Database for the analysis and identified 153,854 children with prenatal anemia exposure and 2,014,619 children without prenatal anemia exposure from 2004 to 2016 and followed them through 2017. Cox regression models were applied to compare the risk of tics or TS between the exposed and nonexposed groups. Among the exposed group, 37,832 were exposed at ≤12 weeks of gestational age (GA) and 116,022 at >12 weeks of GA. We observed an increased risk of tics and TS in those exposed at ≤12 weeks compared with the nonexposed group (adjusted hazard ratio (aHR) = 1.23, 95% confidence interval (CI): 1.12–1.34). The result remained consistent after adjusting for birth year, sex, birth order, maternal age, low-income levels, gestational age, birth weight, and alcohol use and smoking during pregnancy (aHR = 1.16, CI: 1.04–1.28). Fetuses exposed to maternal anemia at ≤12 weeks of GA are at high risk of tics or TS. However, this effect was attenuated to insignificance in the sibling comparison. Our study highlights the importance of detection of anemia during pregnancy and proper timing of iron supplementation.

The Relationship between Iron Deficiency Anemia and Dental caries

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Salahuldeen Hamid AbdelFattah ◽  
Wafaa Ezzat Ibrahim ◽  
Rasha Adel Fathy ◽  
Reham Khaled Abou-El-Fadl
Keyword(s):  
Dental Caries ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Multiple Regression Model ◽  
Deficiency Anemia ◽  
Dmf Index ◽  
Gingival Health ◽  
Increased Risk ◽  
Iron Profile ◽  
The Relationship

Abstract Background Iron deficiency anemia and dental caries are among the most prevalent diseases in some developing countries. However, few studies have been conducted to assess the association between Iron deficiency anemia (IDA) and early childhood caries (ECC). Objectives The aim of the study was to assess the association between IDA and ECC. Methods 40 children with proved iron deficiency anemia (using iron profile panel done initially) and another 40 healthy age and sex-matched children were examined by one trained and calibrated dentist where the oral status of all enrolled children was assessed in terms of the Decayed, Missing, Filled (DMF) index and gingival health using Gingival index of Loe and Sillness. Results Children with anemia had a significantly higher DMF index (4.37±4.44) than children without anemia (0.50±0.90) (P < 0.001). It was found that there was a negative significant correlation between DMF index and the presence of anemia (r= -0.60, P < 0.001), hemoglobin level (r= -0.454, P < 0.001) and MCH level (r= -0.380, P = 0.001). The multiple regression model statistically significantly predicted DMF index (P = 0.001), (R2=0.34) and only the presence of anemia was found to add significantly to the model (P = 0.027). Conclusion Children with iron deficiency anemia have increased risk for development of dental caries than children without anemia. Any children with significant dental caries should be investigated for IDA and anemia should be treated if present.

scholarly journals The risk of fibromyalgia in patients with iron deficiency anemia: a nationwide population-based cohort study

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Wei-Cheng Yao ◽  
Hsuan-Ju Chen ◽  
Kam-Hang Leong ◽  
Kai-Lan Chang ◽  
Yu-Ting Tina Wang ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Blood Transfusion ◽  
Iron Deficiency Anemia ◽  
Proportional Hazards ◽  
Cox Proportional Hazards ◽  
Deficiency Anemia ◽  
Incidence Density ◽  
Research Database ◽  
Iron Supplement ◽  
Increased Risk

AbstractSince iron is essential for neurotransmitter synthesis, decreased iron stores might lead to reduced production of biogenic amines which phenomenon was shown in Fibromyalgia (FM) patients. The aims are to investigate the association of iron deficiency anemia (IDA) and FM and to find the effects of different interventions. We conducted a study using the Taiwan National Health Insurance Research Database. The IDA cohort consisted of 13,381 patients with newly diagnosed IDA between 2000 and 2008. Each patient with IDA was frequency-matched with one people without IDA, by sex, age and index year. The Cox proportional hazards regression analysis was conducted to estimate the association between IDA and FM risk. The event was the occurrence of FM. The overall incidence density rate of FM in the IDA cohort was higher than in the non-IDA cohort with a multivariable Cox proportional hazards model measured adjusted hazard ratio [HR], 1.19; 95% confidence interval [CI], 1.13–1.25). When using non-IDA group as reference, we compared with different therapies for IDA. The adjusted HRs of FM were 1.38 (95% CI = 1.30–1.47), 1.10 (95% CI = 1.03–1.16), 1.18 (95% CI = 0.98–1.43) and 0.73 (95% CI = 0.58–0.90) for IDA patient without therapy, iron supplement alone, blood transfusion alone and both iron supplement and blood transfusion respectively. Our results suggest IDA is associated with an increased risk of FM. All patients should have iron supplementation both to correct anemia and replenish body stores.

Iron Deficiency Anemia Following Prenatal Nutrition Interventions

2007 ◽  
Vol 68 (4) ◽  
pp. 222-225
Author(s):  
Caroline P. Leblanc ◽  
France M. Rioux
Keyword(s):  
Iron Deficiency ◽  
Pregnant Women ◽  
Iron Deficiency Anemia ◽  
Low Income ◽  
Mean Corpuscular Volume ◽  
Serum Iron ◽  
Transferrin Saturation ◽  
Deficiency Anemia ◽  
Corpuscular Volume ◽  
Prevalence Of Anemia

Purpose: Iron deficiency anemia (IDA) during pregnancy and infancy is still common in developed countries, especially in low-income groups. We examined the prevalence of anemia and IDA in healthy low-income pregnant women participating in the Early Childhood Initiatives (ECI) program, and in their infants when they reached six months of age. Methods: Pregnant women were recruited by nutritionists. In mothers, hemoglobin (Hb), mean corpuscular volume, and serum ferritin (SF) were measured at 36 ± 2 weeks of gestation. In infants, Hb, mean corpuscular volume, SF, serum iron, total iron binding capacity (TIBC), and transferrin saturation (TS) were measured at six months of age. Thirty-one mother-infant pairs participated. Results: Among the 31 pregnant women participating in the ECI program, six (19.4%) were anemic (Hb <110 g/L) and five (16.1%) suffered from IDA (Hb <110 g/L and SF <10 µg/L). Among infants, seven of 23 (30.4%) were anemic (Hb <110 g/L) and five of 23 (21.7%) suffered from IDA (Hb <110 g/L plus two of the following: TIBC >60 µmol/L, SF <10 µg/L, serum iron <5.3 µmol/L, TS ≤15%). Conclusions: The prevalence of anemia in this group of lowincome pregnant women is comparable to that in privileged women. The prevalence of IDA in infants is comparable to that observed in other high-risk groups. Effective strategies are needed to prevent IDA in vulnerable groups.

scholarly journals Study of efficacy of intravenous iron sucrose therapy in iron deficiency anaemia of pregnancy

2013 ◽  
Vol 11 (2) ◽  
pp. 107-110
Author(s):  
M Vijayasree
Keyword(s):  
Iron Deficiency ◽  
Gestational Age ◽  
Economic Status ◽  
Intravenous Iron ◽  
Lower Class ◽  
Iron Sucrose ◽  
Deficiency Anemia ◽  
P Value ◽  
Economic Class ◽  
Target Haemoglobin

Background: Anaemia is the most common medical disorder in pregnancy and is responsible for higher of the maternal deaths in the developing countries. Objective: To determine the efficacy of intravenous iron sucrose, in anemic pregnant women, presenting at Mamata General Hospital, Khammam. Methods: Fifty patients with proved iron deficiency anemia having haemoglobin between 8-10gm% were included in the study. Total iron deficit was calculated by standard formula. Target haemoglobin to be achieved was 11gm%. Iron sucrose was administered by intravenous infusion in divided doses. Haemoglobin was repeated 3 weeks after the last dose of intravenous iron sucrose. Gestational Age, Socio economic class distribution was calculated in percentage , Pre and post treatment Hb% was calculated by mean and standard deviation and P-value was Assessed. Results: Majority of the patients i.e. 60% had gestational age between 32-34 weeks, 30% were in between 29-31 weeks of gestational age while 10% were between 26-28 weeks gestation. The Mean gestational age was 32.4±2.7. Distribution of cases by socio economic status showed, 40% belonged to lower class, 32% belonged to middle class and 28% were from upper class. Intravenous iron sucrose therapy was effective in 90% of the patients without any side effects. There were no allergic reactions. Conclusion: This study showed a significant improvement in the haemoglobin of the patients who received iron sucrose infusion. Patients achieved the target of 11 gram % haemoglobin. It was safe and well tolerated. Health Renaissance, January-April 2013; Vol. 11 No.1; 107-110 DOI: http://dx.doi.org/10.3126/hren.v11i2.8216

Comparison of Various Treatment Modalities of Iron Deficiency Anemia in Pregnancy

2017 ◽  
Vol 1 (1) ◽  
pp. 23-26
Author(s):  
Pramya Nanjundan
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Low Income ◽  
Low Income Countries ◽  
Treatment Modalities ◽  
Deficiency Anemia ◽  
Health Goal ◽  
Public Health Goal ◽  
Anemia In Pregnancy ◽  
In Pregnancy

ABSTRACT More than a quarter of the world’s population is anemic, with about one half of the burden from iron deficiency. Iron deficiency anemia occurs when iron deficiency is severe enough to diminish erythropoiesis and cause the development of anemia. The prevention and treatment of iron deficiency is a major public health goal especially in women, children, and individuals from low-income countries. How to cite this article Nanjundan P. Comparison of Various Treatment Modalities of Iron Deficiency Anemia in Pregnancy. World J Anemia 2017;1(1):23-26.

The relationship between iron parameters and platelet parameters in women with iron deficiency anemia and thrombocytosis

Platelets ◽  
2012 ◽  
Vol 24 (5) ◽  
pp. 348-351 ◽  
Author(s):  
Mi-Jung Park ◽  
Pil-Whan Park ◽  
Yiel-Hea Seo ◽  
Kyung-Hee Kim ◽  
Soon-Ho Park ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Iron Parameters ◽  
The Relationship
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