scholarly journals Association between Adverse Effects and Parental Beliefs about Antiepileptic Medicines

Medicina ◽  
2018 ◽  
Vol 54 (4) ◽  
pp. 60 ◽  
Author(s):  
Violeta Ilić ◽  
Dragana Bogićević ◽  
Branislava Miljković ◽  
Sandra Vezmar-Kovačević
Keyword(s):  
Adverse Effects ◽  
Antiepileptic Drugs ◽  
Parental Education ◽  
Febrile Seizures ◽  
Parental Beliefs ◽  
Parental Concerns ◽  
Upset Stomach ◽  
Antiepileptic Medications ◽  
The University ◽  
Beliefs About Medications

Background and Aim: Adverse effects are common in children treated with antiepileptic medications and may affect parental beliefs about treatment. The aim of the study was to investigate the relationship between adverse effects and parental beliefs about antiepileptic drugs used for the treatment of their children. Methods: The study was performed at the University Children’s Hospital, Belgrade, Serbia from 2013–2015. Parents of children treated with valproic acid, carbamazepine or lamotrigine, were eligible. They were asked to fill in the Beliefs about Medications Questionnaire (BMQ) and The Liverpool Adverse Events Profile (LAEP). Results: Parents of 127 children (average age 9.88 ± 4.16 years) of whom 111 had epilepsy (67 generalized, 44 focal) and 16 with febrile seizures participated in the study. Nervousness and/or agitation, weight gain, restlessness, headache, difficulty in concentrating, feeling of aggression and upset stomach were most frequent adverse effects, reported in 37% of the population. BMQ-specific necessity scores significantly correlated with parental education; parents with elementary school showed lower scores than those with higher education. The presence of difficulty in concentrating of their child was associated with higher BMQ concern scores (20.73 ± 4.25 vs. 18.99 ± 3.60, p = 0.043) as well as necessity scores (18.42 ± 3.31 vs. 16.40 ± 2.73, p = 0.017). Higher scores of BMQ-general overuse were reported in the presence of a headache (8.79 ± 2.81 vs. 7.64 ± 2.72, p = 0.027). Conclusions: The main finding of our study is that parental beliefs about antiepileptic drugs were associated with the presence of adverse effects. Understanding this relationship could allow physicians and pharmacists to structure better educational programs for parents of children treated with antiepileptic drugs. Education should be more focused towards understanding the adverse effects of antiepileptics which could alleviate parental concerns and strengthen their beliefs about the necessity of medication use in their children.

Children With Seizures: When Can Treatment Be Deferred?

1994 ◽  
Vol 9 (2_suppl) ◽  
pp. 288-2S13 ◽  
Author(s):  
Elaine Wyllie
Keyword(s):  
Adverse Effects ◽  
Focal Epilepsy ◽  
Febrile Seizures ◽  
Individual Case ◽  
Benefit Analysis ◽  
Unprovoked Seizure ◽  
Clinical Scenarios ◽  
Antiepileptic Drug Treatment ◽  
Antiepileptic Medications ◽  
Risk Benefit Analysis

The decision whether or not to recommend chronic antiepileptic drug treatment for a child with seizures requires a risk-benefit analysis tailored to each individual case. Because all of the available antiepileptic medications have some potential adverse effects, the analysis may weigh in favor of a decision not to treat. Three clinical scenarios in pediatrics in which the no-treatment option may often be appropriate include a single unprovoked seizure, febrile seizures, and benign focal epilepsy of childhood. (J Child Neurol 1994;9(Suppl);2S8-2S13).

Overview of Lamotrigine and the New Antiepileptic Drugs: The Challenge

1997 ◽  
Vol 12 (1_suppl) ◽  
pp. S48-S52 ◽  
Author(s):  
John M. Pellock
Keyword(s):  
Adverse Effect ◽  
Adverse Effects ◽  
Antiepileptic Drugs ◽  
Adjunctive Therapy ◽  
Dose Titration ◽  
Childhood Epilepsy ◽  
Major Advance ◽  
New Antiepileptic Drugs ◽  
Life Threatening ◽  
Titration Schedule

Lamotrigine, like all antiepileptic drugs, can be effective when used as monotherapy or adjunctive therapy. In general, adverse effects are reduced when monotherapy is employed. The most frequent adverse effect prompting withdrawal of lamotrigine is rash. This potentially life-threatening adverse effect occurs more frequently in children, is increased when a rapid dose titration schedule is employed, and is greater when lamotrigine is prescribed in combination with valproate. The availability of lamotrigine and other antiepileptic drugs represents a major advance for the treatment of childhood epilepsy. The challenge in using all of the new antiepileptic drugs, including lamotrigine, is to balance the expected improved efficacy with the potentially serious adverse effects. (J Child Neurol 1997;12(Suppl 1):S48-S52).

scholarly journals Understanding parent concerns about children’s diet, activity and weight status: an important step towards effective obesity prevention interventions

2009 ◽  
Vol 13 (8) ◽  
pp. 1221-1228 ◽  
Author(s):  
Amy Slater ◽  
Jane Bowen ◽  
Nadia Corsini ◽  
Claire Gardner ◽  
Rebecca Golley ◽  
...  
Keyword(s):  
Parental Education ◽  
Weight Status ◽  
Well Being ◽  
Computer Assisted ◽  
Parental Education Level ◽  
Parental Concerns ◽  
Parental Characteristics ◽  
Prevention Interventions ◽  
Influence Of Food ◽  
Parent Concerns

AbstractObjectiveTo identify parents’ concerns and attitudes towards children’s diets, activity habits and weight status.DesignComputer-assisted telephone interviewing administration of a 37-item survey. Data were weighted for parental education level. Descriptive results are presented, and comparisons are made by the age, gender and parental characteristics of the child.SettingOnline research panel of Australian parents.SubjectsA total of 1202 randomly selected parents of children aged 2–16 years, broadly representative of the Australian population.ResultsParents were concerned about their child’s education (reported by 35 % of respondents), child’s health and well-being (25 %), and violence, drugs and alcohol (20 %). Concern about nutrition was indicated by 14 % of respondents and concern about fitness/exercise was indicated by 3 % of the sample. Factors perceived as making a healthy diet difficult to achieve for their child were child resistance (89 %), the availability of healthy food (72 %), a busy lifestyle (67 %) and the influence of food advertising (63 %). Ninety-two per cent of parents thought that it was realistic for their child to be active for at least 1 h/d, with 75 % of parents feeling that it was realistic for their child to have less than 2 h recreational screen time per d. Despite this, common barriers to achieving the activity guidelines were lack of time, weather and keeping children occupied.ConclusionsInsights into parental concerns from the current study may be useful in guiding development of interventions to improve children’s nutrition and physical activity habits by framing messages in a way that are most likely to resonate with parents.

scholarly journals The Cultural Revolution in David Lodge’s Changing Places

2019 ◽  
Author(s):  
AWEJ-tls for Translation & Literary Studies ◽  
Noureddine Friji
Keyword(s):  
Adverse Effects ◽  
University Students ◽  
Cultural Heritage ◽  
Cultural Revolution ◽  
Aesthetic Value ◽  
Cultural Traditions ◽  
One Dimensional ◽  
German Philosopher ◽  
The Aesthetic ◽  
The University

Utilizing Herbert Marcuse’s One-Dimensional Man (1962) and Counterrevolution and Revolt (1972) as a theoretical backdrop, this article seeks to gauge the extent to which the teachings of the German philosopher and political theorist lay the groundwork for the protests mounted by the university students in David Lodge’s campus novel Changing Places (1975). Admittedly, the Student Revolution spilled over into numerous fields. However, given space restrictions, only its cultural manifestations will be examined. It will be clear that at the root of Lodge’s students’ uprising lies an overpowering urge to break with the cultural heritage and with the academics upholding it. It will be equally clear, nonetheless, that these young activists’ faith in Marcuse’s political doctrine is unwelcome to conservative academics on the ground that it has diverse adverse effects on universities. Not only are politically oriented texts and discourses given precedence over traditional ones but also teachers and administrators are, at times, hindered from doing their duties. The plausible conclusion to draw, in the light of the research’s findings, is that although cultural revolutions undeniably pave the way for a number of personal and collective achievements and help us modernize many aspects of life, they should not blind us to the enduring significance of previous cultural traditions and of the aesthetic value of literary works.

scholarly journals The use of social networking sites and their relation to the behavior of the university student: استخدام مواقع التواصل الاجتماعي وعلاقتها بالسلوك الانحرافي لدى الطالب الجامعي

2017 ◽  
Vol 1 (5) ◽  
Author(s):  
Djeboub Walid
Keyword(s):  
Adverse Effects ◽  
Social Networking ◽  
Social Networking Sites ◽  
Deviant Behavior ◽  
Negative Impact ◽  
Sampling Technique ◽  
Simple Random Sampling ◽  
The University ◽  
The Impact ◽  
University Community

This study aimed to show the extent of teenagers who represent students Tèbessa University contents of violence and crime that is seen or published or traded them through the media and communication affected, especially through social networking sites and networks, such as Facebook and stringing YouTube and Skype, etc., which may contribute to the formation and strengthening of behaviors negative in these through the following problem: Do you contribute to social networking sites through the implications of violence and crime in a negative impact on the behaviors of the students within the university community ?, also deliberately researcher to sample the estimated inventory of 50 students schooled at the Faculty of Economics and Commercial Sciences and Management Sciences of each section by an estimated 10% of the study population as a whole's (2000) the adoption of simple random sampling technique, the results have also been addressing the adoption system (SPSS) , Which resulted in the results: the presence of a statistically significant correlation between the students' use of social networking sites and the spread of deviant behavior within the university community?, And no statistically significant differences in the adverse effects of the use of social networking sites on the behavior of students depending on the sex variable, the largest of any female average for the benefit of, No statistically significant differences in the adverse effects of the use of social networking sites on the behavior of students depending on the variable physical level ?,No statistically significant differences in the adverse effects of the use of social networking sites on the behavior of the students due to the level of scientific student ?,The study also called attention to the recent media study the impact of the implications of violence and crime across social networking on the behavior of young people and adolescents sites, spreading awareness programs to help solve the problems of this phenomenon.

Antiepileptic Medication Use in Neurosurgical Patients

2019 ◽  
pp. 74-87
Author(s):  
Megan Margiotta ◽  
Timothy Ambrose
Keyword(s):  
United States ◽  
Antiepileptic Drugs ◽  
Medication Use ◽  
The United States ◽  
Inpatient Setting ◽  
Risks And Benefits ◽  
Antiepileptic Medication ◽  
Neurosurgical Patients ◽  
Potential Risks ◽  
Antiepileptic Medications

When caring for neurosurgical patients, many will either be started on a new antiepileptic medication or will be continued on a regimen that had been started prior to hospitalization. Because of this, it is important for a hospitalist to be familiar with the potential risks and benefits of these medications, even though they may be initiated by a neurosurgeon or neurologist. This chapter discusses several common antiepileptic drugs and their uses in the inpatient setting. This is not intended to be an exhaustive discussion; as of this writing, there are at least 27 unique antiepileptic medications available in the United States alone, with more being studied and produced.

scholarly journals The Political Knowledge of University Students (A Comparative Study between Jordan and Libya)

2017 ◽  
Vol 13 (11) ◽  
pp. 13
Author(s):  
Alfeetouri Salih Mohammed Alsati ◽  
Al-Sayed Abd ulmutallab Ghanem
Keyword(s):  
University Students ◽  
Political Institutions ◽  
Parental Education ◽  
Political Process ◽  
Political Knowledge ◽  
The Political ◽  
The Social ◽  
The Difference ◽  
The University

The current research aims at identifying and measuring the political knowledge of the students of the two universities of Al- Balqaa in Jordan and Omar Al- Mokhtar in Libya. The two communities are almost similar in terms of the social formation, Arab customs and traditions, the Bedouin values, the difference in the institutional age and the political stability.The study attempts to measure and compare the political knowledge in the communities of the two universities using the descriptive and comparative analytical method. The study uses a 400 random questionnaire of 30 paragraphs to measure eight indicators divided into internal and external political knowledge, and other aspects of knowledge: general political knowledge, knowledge of the political institutions and leaders, the political interest, the geographical and historical knowledge, and knowledge of the methods of exercising the political process. The study also attempts to identifying the most important sources and the role of the university in university students’ political knowledge.The results show that the level of the political knowledge is medium while its level in the sample of the Jordanian students is high. According to the samples, the internal political knowledge is more than the external knowledge with a lack of interest in the political matters. The samples do not consider the political matters as their priorities. The political knowledge as a whole needs to much effort to be exerted to confront the current circumstances. The variables of the place of resident, age and the educational level make big difference in the political knowledge. In contrast, the level of the parental education does not create big differences.

Should Off Label Antiepileptic Drugs Be Used for Treatment of Infancy and Childhood Epilepsy? Discussions Based on a Dravet Syndrome Case Report

2020 ◽  
Vol 9 (03) ◽  
pp. 080-082
Author(s):  
Mihaela-Adela Vintan
Keyword(s):  
Antiepileptic Drugs ◽  
Febrile Seizures ◽  
Dravet Syndrome ◽  
Psychomotor Development ◽  
Older Children ◽  
Off Label ◽  
Infancy And Childhood ◽  
Term Administration ◽  
Long Term Prognosis

AbstractEpilepsy represents a burdensome neurological disorder with higher incidence before the age of 18 years. The treatment is medical and involves long-term administration of antiepileptic drugs (AED). There are known high-resistant syndromes with onset in infancy and childhood, Dravet syndrome, being one of them. It is a well-known fact that early seizures treatment prevents associated comorbidities, cognitive and motor disabilities, and improve long-term prognosis. There are several AEDs available but not all of them are approved for use in infants. This is due to the need for additional toxicology studies at this age and for development of suitable formulations.A 14-month-old girl with Dravet syndrome was presented here. Prompt diagnosis was made based on clinical features and confirmed by the genetic tests. She partially responded to valproate and clobazam but continued to have prolonged febrile seizures. We added stiripentol after consulting reports of studies in infants younger than 2 years and after obtaining family consent. She responded well with decrease in episodes of status epilepticus and improvement in psychomotor development and stiripentol was tolerated well. Off label use of certain AEDs can benefit infants when there are no major pharmacokinetic differences in comparison to older children.

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