scholarly journals Porous Titanium Surfaces to Control Bacteria Growth: Mechanical Properties and Sulfonated Polyetheretherketone Coatings as Antibiofouling Approaches

Metals ◽  
2019 ◽  
Vol 9 (9) ◽  
pp. 995 ◽  
Author(s):  
Ana M. Beltrán ◽  
Ana Civantos ◽  
Cristina Dominguez-Trujillo ◽  
Rocío Moriche ◽  
José A. Rodríguez-Ortiz ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Mean Free Path ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Equivalent Diameter ◽  
Bacterial Strains ◽  
Bacteria Growth ◽  
Chemical Surface ◽  
Titanium Surfaces ◽  
Synthetic Coating

Here, titanium porous substrates were fabricated by a space holder technique. The relationship between microstructural characteristics (pore equivalent diameter, mean free-path between pores, roughness and contact surface), mechanical properties (Young’s modulus, yield strength and dynamic micro-hardness) and bacterial behavior are discussed. The bacterial strains evaluated are often found on dental implants: Methicillin-resistant Staphylococcus aureus (MRSA) and Pseudomonas aeruginosa. The colony-forming units increased with the size of the spacer for both types of studied strains. An antibiofouling synthetic coating based on a sulfonated polyetheretherketone polymer revealed an effective chemical surface modification for inhibiting MRSA adhesion and growth. These findings collectively suggest that porous titanium implants designed with a pore size of 100–200 µm can be considered most suitable, assuring the best biomechanical and bifunctional anti-bacterial properties.

scholarly journals Electrical Impedance of Surface Modified Porous Titanium Implants with Femtosecond Laser

Materials ◽  
2022 ◽  
Vol 15 (2) ◽  
pp. 461
Author(s):  
Paula Navarro ◽  
Alberto Olmo ◽  
Mercè Giner ◽  
Marleny Rodríguez-Albelo ◽  
Ángel Rodríguez ◽  
...  
Keyword(s):  
Cell Culture ◽  
Femtosecond Laser ◽  
Laser Treatment ◽  
Electrical Impedance ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Electrical Impedance Spectroscopy ◽  
Wide Range ◽  
Titanium Surfaces ◽  
Surface Modified

The chemical composition and surface topography of titanium implants are essential to improve implant osseointegration. The present work studies a non-invasive alternative of electrical impedance spectroscopy for the characterization of the macroporosity inherent to the manufacturing process and the effect of the surface treatment with femtosecond laser of titanium discs. Osteoblasts cell culture growths on the titanium surfaces of the laser-treated discs were also studied with this method. The measurements obtained showed that the femtosecond laser treatment of the samples and cell culture produced a significant increase (around 50%) in the absolute value of the electrical impedance module, which could be characterized in a wide range of frequencies (being more relevant at 500 MHz). Results have revealed the potential of this measurement technique, in terms of advantages, in comparison to tiresome and expensive techniques, allowing semi-quantitatively relating impedance measurements to porosity content, as well as detecting the effect of surface modification, generated by laser treatment and cell culture.

Anodization: A Promising Nano-Modification Technique of Titanium Implants for Orthopedic Applications

2006 ◽  
Vol 6 (9) ◽  
pp. 2682-2692 ◽  
Author(s):  
Chang Yao ◽  
Thomas J. Webster
Keyword(s):  
Titanium Oxide ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Protective Oxide ◽  
Surface Features ◽  
Modification Technique ◽  
Titanium Surfaces ◽  
Anodized Titanium ◽  
Orthopedic Applications ◽  
Porous Titanium Oxide

Anodization is a well-established surface modification technique that produces protective oxide layers on valve metals such as titanium. Many studies have used anodization to produce micro-porous titanium oxide films on implant surfaces for orthopedic applications. An additional hydrothermal treatment has also been used in conjunction with anodization to deposit hydroxyapatite on titanium surfaces; this is in contrast to using traditional plasma spray deposition techniques. Recently, the ability to create nanometer surface structures (e.g., nano-tubular) via anodization of titanium implants in fluorine solutions have intrigued investigators to fabricate nano-scale surface features that mimic the natural bone environment. This paper will present an overview of anodization techniques used to produce micro-porous titanium oxide structures and nano-tubular oxide structures, subsequent properties of these anodized titanium surfaces, and ultimately their in vitro as well as in vivo biological responses pertinent for orthopedic applications. Lastly, this review will emphasize why anodized titanium structures that have nanometer surface features enhance bone forming cell functions.

A porous bioactive titanium implant for spinal interbody fusion: an experimental study using a canine model

2007 ◽  
Vol 7 (4) ◽  
pp. 435-443 ◽  
Author(s):  
Mitsuru Takemoto ◽  
Shunsuke Fujibayashi ◽  
Masashi Neo ◽  
Kazutaka So ◽  
Norihiro Akiyama ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Histological Examination ◽  
Interbody Fusion ◽  
Average Pore Size ◽  
Spinous Process ◽  
Fibrous Tissue ◽  
Porous Titanium ◽  
Titanium Implants ◽  
Average Pore ◽  
New Generation

Object Porous biomaterials with adequate pore structure and appropriate mechanical properties are expected to provide a new generation of devices for spinal interbody fusion because of their potential to eliminate bone grafting. The purpose of this study was to evaluate the fusion characteristics of porous bioactive titanium implants using a canine anterior interbody fusion model. Methods Porous titanium implants sintered with volatile spacer particles (porosity 50%, average pore size 303 μm, compressive strength 116.3 MPa) were subjected to chemical and thermal treatments that give a bioactive microporous titania layer on the titanium surface (BT implant). Ten adult female beagle dogs underwent anterior lumbar interbody fusion at L6–7 using either BT implants or nontreated (NT) implants, followed by posterior spinous process wiring and facet screw fixation. Radiographic evaluations were performed at 1, 2, and 3 months postoperatively using X-ray fluoroscopy. Animals were killed 3 months postoperatively, and fusion status was evaluated by manual palpation and histological examination. Results Interbody fusion was confirmed in all five dogs in the BT group and three of five dogs in the NT group. Histological examination demonstrated a large amount of new bone formation with marrowlike tissue in the BT implants and primarily fibrous tissue formation in the NT implants. Conclusions Bioactive treatment effectively enhanced the fusion ability of the porous titanium implants. These findings, coupled with the appropriate mechanical properties in load-bearing conditions, indicate that these porous bioactive titanium implants represent a new generation of biomaterial for spinal interbody fusion.

Mechanical Properties of Porous Titanium Structure Fabricated by Investment Casting with Pressurization/Depressurization System

2014 ◽  
Vol 52 (3) ◽  
pp. 203-209 ◽  
Author(s):  
San Kang ◽  
Ji Woon Lee ◽  
Soong Keun Hyun ◽  
Byong Pil Lee ◽  
Myoung Gyun Kim ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Investment Casting ◽  
Porous Titanium ◽  
Titanium Structure

scholarly journals Understanding long-term silver release from surface modified porous titanium implants

2017 ◽  
Vol 58 ◽  
pp. 550-560 ◽  
Author(s):  
Anish Shivaram ◽  
Susmita Bose ◽  
Amit Bandyopadhyay
Keyword(s):  
Porous Titanium ◽  
Titanium Implants ◽  
Silver Release ◽  
Surface Modified

The Effect of Curcumin against In Vitro Adhesion of Implant Device-Associated Bacteria on Nanosized Titanium Dioxide

2013 ◽  
Vol 23 ◽  
pp. 83-90
Author(s):  
Seung Han Oh ◽  
In Young Na ◽  
Kyoung Hee Choi
Keyword(s):  
Titanium Dioxide ◽  
Bacterial Adhesion ◽  
Curcuma Longa ◽  
Human Tooth ◽  
Bacterial Strains ◽  
Associated Bacteria ◽  
Tooth Surfaces ◽  
Titanium Surfaces ◽  
Main Component

Although titanium dioxide (TiO2) is an implantable biomaterial with its antibacterial activity, infection on TiO2 surfaces remains a problem for medical settings. According to our previous studies, curcumin, the main component of turmeric (Curcuma longa), partially hindered the attachment of Streptococcus mutans to human tooth surfaces. Therefore, it was examined whether several implant device-associated bacteria were able to adhere to nanosized TiO2 surfaces. In addition, the effect of curcumin on the bacterial adhesion was investigated. Bacterial strains were cultured on pure Ti and TiO2 surfaces with various nanotube sizes in the absence or presence of curcumin and observed by scanning electron microscopy. Consequently, most bacteria adhered to Ti and TiO2 surfaces. However, curcumin increased the adhesion of bacteria including S. mutans. The results suggest that bacterial adhesion to implant titanium surfaces can be augmented via curcumin ingestion.

Microstructure Evolution and Mechanical Properties of Rheoformed YL112 Aluminum Alloy

2008 ◽  
Vol 141-143 ◽  
pp. 163-168 ◽  
Author(s):  
Xiang Jie Yang ◽  
Hong Min Guo
Keyword(s):  
Mechanical Properties ◽  
Aluminum Alloy ◽  
Shape Factor ◽  
Die Casting ◽  
Equivalent Diameter ◽  
Uniform Microstructure ◽  
Casting Aluminum Alloy ◽  
Casting Aluminum ◽  
Semi Solid ◽  
Secondary Solidification

Rheo-die casting (RDC) based on LSPSF (low superheat pouring with a shear field) rheocasting process has been exploited. In case of secondary die casting aluminum alloy YL112, LSPSF allowed for preparation of sound semi-solid slurry in 15-20s that fully meet the production rate of HPDC, the primary α-Al exhibiting a mean equivalent diameter of 70 μm and shape factor of 0.93, without any entrapped eutectic. Compared to conventional HPDC, RDC improves microstructures in castings. Secondary solidification of semi-solid slurry takes place uniformly throughout the entire cavity, producing an extremely fine and uniform microstructure. The experimental results show the RDC 380 alloy has much improved integrity and mechanical properties, particularly elongation, and heat treatment can be used to enhance the mechanical properties.

Effect of Cellulose Functionalization on Thermal and Mechanical Properties of Epoxy Resin

2017 ◽  
Vol 757 ◽  
pp. 62-67 ◽  
Author(s):  
Kritsanachai Leelachai ◽  
Supissara Ruksanak ◽  
Tarakol Hongkeab ◽  
Supakeat Kambutong ◽  
Raymond A. Pearson ◽  
...  
Keyword(s):  
Mechanical Properties ◽  
Fracture Toughness ◽  
Diglycidyl Ether ◽  
Cellulose Content ◽  
Thermal And Mechanical Properties ◽  
Chemical Surface ◽  
Pull Out ◽  
Fiber Bridging ◽  
Surface Modified ◽  
Modified Epoxy

In this study, diglycidyl ether of bisphenol A (DGEBA) cured cycloaliphatic polyamine was modified with functionalized celluloses for improved thermal and mechanical properties. Three different types of surface-modified cellulose, polyacrylamide-g-cellulose (PGC), aminopropoxysilane-g-cellulose (SGC), and carboxymethyl cellulose (CMC), were investigated and used as reinforcing agents in epoxy resins. The storage modulus of these modified epoxy systems was found to significantly increase with addition of cellulose fillers (up to 1 wt. % cellulose content). An improved fracture toughness (KIC) was also observed with increasing cellulose loading content with PGC and SGC. Among the surface-modified celluloses, epoxy modified with SGC was found to have the highest fracture toughness followed by PGC and CMC at 1.0 wt.% cellulose addition due to the chemical surface compatibility. The toughening mechanisms of the cellulose/epoxy composites, measured by scanning electron microscopy (SEM), revealed that fiber-debonding, fiber-bridging, and fiber-pull out were responsible for increased toughness.

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