scholarly journals The Applications of 3D Printing for Craniofacial Tissue Engineering

Micromachines ◽  
2019 ◽  
Vol 10 (7) ◽  
pp. 480 ◽  
Author(s):  
Owen Tao ◽  
Jacqueline Kort-Mascort ◽  
Yi Lin ◽  
Hieu M. Pham ◽  
André M. Charbonneau ◽  
...  

Three-dimensional (3D) printing is an emerging technology in the field of dentistry. It uses a layer-by-layer manufacturing technique to create scaffolds that can be used for dental tissue engineering applications. While several 3D printing methodologies exist, such as selective laser sintering or fused deposition modeling, this paper will review the applications of 3D printing for craniofacial tissue engineering; in particular for the periodontal complex, dental pulp, alveolar bone, and cartilage. For the periodontal complex, a 3D printed scaffold was attempted to treat a periodontal defect; for dental pulp, hydrogels were created that can support an odontoblastic cell line; for bone and cartilage, a polycaprolactone scaffold with microspheres induced the formation of multiphase fibrocartilaginous tissues. While the current research highlights the development and potential of 3D printing, more research is required to fully understand this technology and for its incorporation into the dental field.

2020 ◽  
Vol 1 (2) ◽  
pp. 81-91
Author(s):  
Frince Marbun ◽  
Richard A.M. Napitupulu

3D printing technology has great potential in today's manufacturing world, one of its uses is in making miniatures or prototypes of a product such as a piston. One of the most famous and inexpensive 3D printing (additive manufacturing) technologies is Fused Deposition Modeling (FDM), the principle FDM works by thermoplastic extrusion through a hot nozzle at melting temperature then the product is made layer by layer. The two most commonly used materials are ABS and PLA so it is very important to know the accuracy of product dimensions. FDM 3D Printing Technology is able to make duplicate products accurately using PLA material. FDM machines work by printing parts that have been designed by computer-aided design (CAD) and then exported in the form of STL or .stl files and uploaded to the slicer program to govern the printing press according to the design. Using Anet A8 brand 3D printing tools that are available to the public, Slicing of general CAD geometry files such as autocad and solidwork is the basis for making this object. This software is very important to facilitate the design process to be printed. Some examples of software that can be downloaded and used free of charge such as Repetier-Host and Cura. by changing the parameters in the slicer software is very influential in the 3D printing manufacturing process.


Author(s):  
B. Li ◽  
T. Dutta Roy ◽  
C. M. Smith ◽  
P. A. Clark ◽  
K. H. Church

Numerous solid freeform fabrication (SFF) or rapid prototyping (RP) techniques have been employed in the field of tissue engineering to fabricate specially organized three-dimensional (3-D) structures such as scaffolds. Some such technologies include, but are not limited to, laminated object manufacturing (LOM), three-dimensional printing (3-DP) or ink-jet printing, selective laser sintering (SLS), and fused deposition modeling (FDM). These techniques are capable of rapidly producing highly complex 3-D scaffolds or other biomedical structures with the aid of a computer-aided design (CAD) system. However, they suffer from lack of consistency and repeatability, since most of these processes are not fully controlled and cannot reproduce the previous work with accuracy. Also, these techniques (excluding FDM) are not truly direct-print processes. Certain material removing steps are involved, which in turn increases the complexity and the cost of fabrication. The FDM process has good repeatability; however, the materials that can be used are limited due to the high temperature needed to melt the feedstock. Some researchers also reported that the scaffolds fabricated by FDM lack consistency in the z-direction. In this paper, we will present a true direct-print technology for repeatedly producing scaffolds and other biomedical structures for tissue engineering with the aid of our Computer Aided Biological (CAB) tool. Unlike other SFF techniques mentioned above, our direct-print process fabricates scaffolds or other complex 3-D structures by extruding (dispensing) a liquid material onto the substrate with a prescribed pattern generated by a CAD program. This can be a layer-by-layer 2.5 dimension build or a true 3-D build. The dispensed liquid material then polymerizes or solidifies, to form a solid structure. The flexibility in the types of materials that can be extruded ranges from polymers to living cells, encapsulated in the proper material. True 3-D structures are now possible on a wide range of substrates, including even in vivo. Some of the advantages of the process are a) researchers have full control over the patterns to be created; b) it is a true direct-print process with no material removing steps involved; c) it is highly consistent and repeatable; and d) it is highly efficient and cost-effective. This paper will first give a detailed description of the CAB tool. Then, it will present a detailed process for printing polycaprolactone (PCL) into a defined 3-D architecture, where the primary focus for these constructs is for use in tissue engineering applications. Finally, mechanical characterization results of the printed scaffolds will be included in the paper.


2021 ◽  
Author(s):  
Mobina Movahedi

Additive manufacturing (AM), 3D printing, is defined as a process of depositing materials layer by layer to create three-dimensional printed models, as opposed to subtractive manufacturing methodologies. It has the potential of revolutionizing field of manufacturing, which allows us to create more complex geometries with lower cost and faster speed in comparison to injection molding, compression forming, and forging. Therefore, 3D printing can shorten the design manufacturing cycle, reduce the production cost, and increase the competitiveness. Due to the improvements of processes and advancements of modeling and design, Fused Deposition Modeling (FDM) technologies, a common 3D printing technique, have been involved in wide various applications in the past three decades and numerous studies have been gathered. This research work studies directional properties of FDM 3D printed thermoplastic parts per ASTM D638. Tensile strength and modulus of the coupons along and perpendicular to the printing direction are evaluated. It is observed that FDM 3D printing introduces anisotropic behavior to the manufactured part, e.g. tensile strength of 57.7 and 30.8 MPa for loading along and perpendicular to the printing direction, respectively. FDM 3D printers are not ideal and introduce defects into the manufactured parts, e.g. in the form of missing material, gap. This study investigates the impact of gaps on tensile strength and modulus of 3D printed parts. A maximum reduction of 20% in strength is found for a gap (missing bead) along the loading direction.


2021 ◽  
Author(s):  
Mobina Movahedi

Additive manufacturing (AM), 3D printing, is defined as a process of depositing materials layer by layer to create three-dimensional printed models, as opposed to subtractive manufacturing methodologies. It has the potential of revolutionizing field of manufacturing, which allows us to create more complex geometries with lower cost and faster speed in comparison to injection molding, compression forming, and forging. Therefore, 3D printing can shorten the design manufacturing cycle, reduce the production cost, and increase the competitiveness. Due to the improvements of processes and advancements of modeling and design, Fused Deposition Modeling (FDM) technologies, a common 3D printing technique, have been involved in wide various applications in the past three decades and numerous studies have been gathered. This research work studies directional properties of FDM 3D printed thermoplastic parts per ASTM D638. Tensile strength and modulus of the coupons along and perpendicular to the printing direction are evaluated. It is observed that FDM 3D printing introduces anisotropic behavior to the manufactured part, e.g. tensile strength of 57.7 and 30.8 MPa for loading along and perpendicular to the printing direction, respectively. FDM 3D printers are not ideal and introduce defects into the manufactured parts, e.g. in the form of missing material, gap. This study investigates the impact of gaps on tensile strength and modulus of 3D printed parts. A maximum reduction of 20% in strength is found for a gap (missing bead) along the loading direction.


2020 ◽  
Vol 3 (01) ◽  
pp. 1-11
Author(s):  
Katia-Emiko Guima ◽  
Felipe L. B. Fialho ◽  
Cauê Alves Martins

Additive manufacturing or 3D-printing is a revolutionary technique for prototyping and building objects for final use. Since the first registers at ~1890 the improved technology has boosted the applications of such technique, decreasing its market price. The most affordable 3D-print technique is Fuse Deposition Modeling (FDM), which is based on a layer-by-layer deposition of a fused polymer on a cooled table. Although FDM has been used by industrials, students and researchers, there are few published protocols dealing with small challenges and daily problems. Here we use a basic object to detail pre- and post-printing steps. This technical note offers the reader tools to model, print and treat the 3D-object. We point out basic challenges, such as positioning the objects on the virtual table of the slicing software, that may lead towards undesirable printed pieces. The protocols described here do not cover the uncountable possibilities of 3D-printing by FDM, but surely help researchers and industrials to start working with it.   DOI: http://dx.doi.org/10.30609/JETI.2020-8625


2020 ◽  
Vol 870 ◽  
pp. 73-80
Author(s):  
Nuha Hadi Jasim Al Hasan

3D printing innovation, as a quick prototyping, utilize plastic or metal as the crude material to print the genuine parts layer by layer. In this way, it is likewise called added substance producing procedure. Contrasted and conventional assembling innovation, 3D printing innovation has evident points of interest in assembling items with complex shapes and structures. Fused deposition modeling (FDM) is one of the most broadly utilized 3D printing advances. Fibers of thermoplastic materials, for example, polylactic acid is for the most part utilized as crude materials. The present examination will concentrate on the effect of the infill density, percent on the flexural strength of polylactic acid. Bending test was performed on different infill density, percent of specimens. According to ASTM D638.14 standards, samples for testing are made in different infill density, percent (20, 30, 40, 50 and 60 %) by using a polylactic acid in 3D machine printing and their tensile tested and the parameters include different fill density, layer high of 0.1 mm , 0.2mm and 0.3 have an effect on the mechanical characterized while the time of printing the sample would be increased with increasing of fill density%. The tensile strength of polylactic acid samples was found at different fill density and a layer thickness. According to test measuring results that the tensile strength, maximum 47.1,47.4, and 48 MPa at 30%,40%,and 50% fill density respectively and 0.1mm height layer and the tensile strength minimum at 60% and 70 % fill density and 0.1 mm height layer thickness. The higher strength results as higher layer thickness 0.3 mm as compared with 0.1 and 0.2 at 30%fill density.


2021 ◽  
Vol 11 (7) ◽  
pp. 3230
Author(s):  
Dimitrios G. Dimogianopoulos ◽  
Dionysios E. Mouzakis

A vibration-testing framework for detecting and identifying failing joints between composite structural members without dedicated equipment (accelerometers, amplifiers) or time-consuming system modeling methods is introduced. The sensing element is a 2826MB Metglas® magnetoelastic strip embedded in one of the members during its 3D-printing (layer-by-layer) fabrication process in fused deposition modeling mode. External dynamic loading of the structure causes changes to the strip’s magnetization, thus inducing voltage to a nearby placed coil in a contactless manner. The resulting signal depends on the structure’s behavior under loading (and therefore its condition), and may be recorded without amplification or filtering by conventional oscilloscopes. Its frequency analysis reveals patterns of shifted frequency and/or altered damping at specific modes attributed to failing joints. Apart from yielding results using less dedicated equipment than other vibration-testing methods, the current framework offers two additional benefits: (i) Excitation may be applied to the same structural point for all monitored joints; (ii) estimation of damping values for a given mode does not have to rely on empirical or system modelling techniques (both requiring dedicated expertise). Test runs with structures formed by two or three composite slabs joined in-series indicate promising results with successful detection and identification of failing joints.


2020 ◽  
Vol 861 ◽  
pp. 182-187
Author(s):  
Vinh Du Nguyen ◽  
Thai Xiem Trinh ◽  
Son Minh Pham ◽  
Trong Huynh Nguyen

Additive manufacturing (3D printing) is a hopeful technique that is used to produce complex geometry parts in a layer-by-layer method. Fused deposition modeling (FDM) is a popular 3D printing technology for producing components of thermoplastic polymers. In FDM process, the part quality is influenced strongly by the printing parameters. Until now, these parameters stil need to be investigated. Therefore, in this study, the influence of FDM 3D printing parameters on the tensile strength of product will be investigated. By experiment, three parameters, that is, layer height, solid layer top, and first-layer height, were studied. The investigation shows that the layer height is the only parameter impacted the tensile strength of the product.


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